Neuropsychology Review最新文献_第8页

Post-stroke Cognition is Associated with Stroke Survivor Quality of Life and Caregiver Outcomes: A Systematic Review and Meta-analysis 中风后认知与中风幸存者的生活质量和照顾者的结果有关：系统回顾与元分析

IF 5.8 2区心理学

Neuropsychology Review Pub Date : 2024-03-11 DOI: 10.1007/s11065-024-09635-5

Renerus J. Stolwyk, Tijana Mihaljcic, Dana K. Wong, Diana Ramirez Hernandez, Brittany Wolff, Jeffrey M. Rogers

{"title":"Post-stroke Cognition is Associated with Stroke Survivor Quality of Life and Caregiver Outcomes: A Systematic Review and Meta-analysis","authors":"Renerus J. Stolwyk, Tijana Mihaljcic, Dana K. Wong, Diana Ramirez Hernandez, Brittany Wolff, Jeffrey M. Rogers","doi":"10.1007/s11065-024-09635-5","DOIUrl":"https://doi.org/10.1007/s11065-024-09635-5","url":null,"abstract":"Disability arising from post-stroke cognitive impairment is a likely contributor to the poor quality of life (QoL) stroke survivors and their carers frequently experience, but this has not been summarily quantified. A systematic literature review and meta-analysis was completed examining the association between general and domain-specific post-stroke cognitive functioning and adult stroke survivor QoL, caregiver QoL, and caregiver burden. Five databases were systematically searched, and eligibility for inclusion, data extraction, and study quality were evaluated by two reviewers using a standardised protocol. Effects sizes (r) were estimated using a random effects model. Thirty-eight studies were identified, generating a sample of 7365 stroke survivors (median age 63.02 years, range 25–93) followed for 3 to 132 months post-stroke. Overall cognition (all domains combined) demonstrated a significant small to medium association with QoL, r = 0.23 (95% CI 0.18–0.28), p < 0.001. The cognitive domains of speed, attention, visuospatial, memory, and executive skills, but not language, also demonstrated a significant relationship with QoL. Regarding caregiver outcomes, 15 studies were identified resulting in a sample of 2421 caregivers (median age 58.12 years, range 18–82) followed for 3 to 84 months post-stroke. Stroke survivor overall cognitive ability again demonstrated a significant small to medium association with caregiver outcomes (QoL and burden combined), r = 0.17 (95% CI 0.10–0.24), p < 0.001. In conclusion, lower post-stroke cognitive performance is associated with significant reductions in stroke survivor QoL and poorer caregiver outcomes. Cognitive assessment is recommended early to identify those at risk and implement timely interventions to support both stroke survivors and their caregivers.","PeriodicalId":49754,"journal":{"name":"Neuropsychology Review","volume":"1 1","pages":""},"PeriodicalIF":5.8,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140099046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Systematic Review of Cognition in Cervical Dystonia. 颈性肌张力障碍认知的系统性回顾。

IF 5.8 2区心理学

Neuropsychology Review Pub Date : 2024-03-01 Epub Date: 2023-01-25 DOI: 10.1007/s11065-022-09558-z

Sarah O'Connor, David Hevey, Tom Burke, Shameer Rafee, Niall Pender, Fiadhnait O'Keeffe

{"title":"A Systematic Review of Cognition in Cervical Dystonia.","authors":"Sarah O'Connor, David Hevey, Tom Burke, Shameer Rafee, Niall Pender, Fiadhnait O'Keeffe","doi":"10.1007/s11065-022-09558-z","DOIUrl":"10.1007/s11065-022-09558-z","url":null,"abstract":"Growing evidence points to a spectrum of non-motor symptoms, including cognitive difficulties that have a greater impact on functional outcomes and quality of life than motor symptoms in cervical dystonia (CD). Some cognitive impairments have been reported; however, findings are inconsistent, and described across mixed groups of dystonia. The current review aimed to examine the evidence for cognitive impairments in CD. MEDLINE, EMBASE, PsychINFO and Web of Science databases were searched. Studies were included if they met the following criteria (i) cross-sectional or longitudinal studies of adults with CD, (ii) where the results of standardised measures of cognitive or neuropsychological function in any form were assessed and reported, (iii) results compared to a control group or normative data, and (iv) were published in English. Results are presented in a narrative synthesis. Twenty studies were included. Subtle difficulties with general intellectual functioning, processing speed, verbal memory, visual memory, visuospatial function, executive function, and social cognition were identified while language, and attention and working memory appear to be relatively spared. Several methodological limitations were identified that should be considered when interpreting the evidence to describe a specific profile of cognitive impairment in CD. Clinical and research implications are discussed.","PeriodicalId":49754,"journal":{"name":"Neuropsychology Review","volume":" ","pages":"134-154"},"PeriodicalIF":5.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10920436/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10619621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Does Olfactory Training Improve Brain Function and Cognition? A Systematic Review. 嗅觉训练能改善大脑功能和认知能力吗？系统回顾。

IF 5.8 2区心理学

Neuropsychology Review Pub Date : 2024-03-01 Epub Date: 2023-02-02 DOI: 10.1007/s11065-022-09573-0

David E Vance, Victor A Del Bene, Vidyulata Kamath, Jennifer Sandson Frank, Rebecca Billings, Do-Yeon Cho, Jun Y Byun, Alexandra Jacob, Joseph N Anderson, Kristina Visscher, Kristen Triebel, Karli M Martin, Wei Li, Frank Puga, Pariya L Fazeli

{"title":"Does Olfactory Training Improve Brain Function and Cognition? A Systematic Review.","authors":"David E Vance, Victor A Del Bene, Vidyulata Kamath, Jennifer Sandson Frank, Rebecca Billings, Do-Yeon Cho, Jun Y Byun, Alexandra Jacob, Joseph N Anderson, Kristina Visscher, Kristen Triebel, Karli M Martin, Wei Li, Frank Puga, Pariya L Fazeli","doi":"10.1007/s11065-022-09573-0","DOIUrl":"10.1007/s11065-022-09573-0","url":null,"abstract":"Olfactory training (OT), or smell training,consists of repeated exposure to odorants over time with the intended neuroplastic effect of improving or remediating olfactory functioning. Declines in olfaction parallel declines in cognition in various pathological conditions and aging. Research suggests a dynamic neural connection exists between olfaction and cognition. Thus, if OT can improve olfaction, could OT also improve cognition and support brain function? To answer this question, we conducted a systematic review of the literature to determine whether there is evidence that OT translates to improved cognition or altered brain morphology and connectivity that supports cognition. Across three databases (MEDLINE, Scopus, & Embase), 18 articles were identified in this systematic review. Overall, the reviewed studies provided emerging evidence that OT is associated with improved global cognition, and in particular, verbal fluency and verbal learning/memory. OT is also associated with increases in the volume/size of olfactory-related brain regions, including the olfactory bulb and hippocampus, and altered functional connectivity. Interestingly, these positive effects were not limited to patients with smell loss (i.e., hyposmia & anosmia) but normosmic (i.e., normal ability to smell) participants benefitted as well. Implications for practice and research are provided.","PeriodicalId":49754,"journal":{"name":"Neuropsychology Review","volume":" ","pages":"155-191"},"PeriodicalIF":5.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891899/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10696074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment Response Following Adaptive PASAT Training for Depression Vulnerability: a Systematic Review and Meta-Analysis. 针对抑郁症易感人群的自适应 PASAT 训练后的治疗反应：系统回顾与 Meta 分析。

IF 5.8 2区心理学

Neuropsychology Review Pub Date : 2024-03-01 Epub Date: 2023-02-28 DOI: 10.1007/s11065-023-09581-8

Yannick Vander Zwalmen, Eveline Liebaert, Kristof Hoorelbeke, Constance Nève de Mévergnies, Chris Baeken, Nick Verhaeghe, Ernst H W Koster

{"title":"Treatment Response Following Adaptive PASAT Training for Depression Vulnerability: a Systematic Review and Meta-Analysis.","authors":"Yannick Vander Zwalmen, Eveline Liebaert, Kristof Hoorelbeke, Constance Nève de Mévergnies, Chris Baeken, Nick Verhaeghe, Ernst H W Koster","doi":"10.1007/s11065-023-09581-8","DOIUrl":"10.1007/s11065-023-09581-8","url":null,"abstract":"In recent years, cognitive control training (CCT) has gained momentum as an intervention to remediate cognitive impairments and decrease depressive symptoms. One promising operationalization to train cognitive control is the adaptive Paced Auditory Serial Addition Task (aPASAT). In this systematic review and meta-analysis of aPASAT training, the efficacy of the intervention and potential moderators were examined. The PsycINFO, MEDLINE, Embase, Web of Science and Cochrane Library electronic databases were searched for studies examining aPASAT training for depressive symptomatology or rumination. Nineteen studies (n = 1255) were included, comprising of depressed patients, remitted depressed patients, at-risk, and healthy participants. We found small significant effects directly after training for both depressive symptomatology and rumination, with similar effect sizes at follow-up. Subgroup analyses suggest a significantly higher mean effect of aPASAT training in non-healthy populations for rumination immediately following training, but not for depressive symptomatology. The amount of training sessions did not moderate effects of CCT. aPASAT has a small but significant effect on depressive symptoms, with direct effects immediately after training, as well as sustained long-term effects. It is currently unclear how many sessions are required for sustained effects due to heterogeneity in training dosage and absence of sufficient trials. Our results suggest that aPASAT training may be most effective for at-risk, remitted- and clinically depressed populations. The effect sizes resulting from this meta-analysis could be used to adequately power future research, which could investigate a dose-response relationship and examine potential treatment gains when combining CCT with other antidepressant interventions.","PeriodicalId":49754,"journal":{"name":"Neuropsychology Review","volume":" ","pages":"232-249"},"PeriodicalIF":5.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9117677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Performance Validity Test Failure in the Clinical Population: A Systematic Review and Meta-Analysis of Prevalence Rates. 临床人群中的性能效度测试失败：流行率的系统回顾和元分析。

IF 5.8 2区心理学

Neuropsychology Review Pub Date : 2024-03-01 Epub Date: 2023-03-06 DOI: 10.1007/s11065-023-09582-7

Jeroen J Roor, Maarten J V Peters, Brechje Dandachi-FitzGerald, Rudolf W H M Ponds

{"title":"Performance Validity Test Failure in the Clinical Population: A Systematic Review and Meta-Analysis of Prevalence Rates.","authors":"Jeroen J Roor, Maarten J V Peters, Brechje Dandachi-FitzGerald, Rudolf W H M Ponds","doi":"10.1007/s11065-023-09582-7","DOIUrl":"10.1007/s11065-023-09582-7","url":null,"abstract":"Performance validity tests (PVTs) are used to measure the validity of the obtained neuropsychological test data. However, when an individual fails a PVT, the likelihood that failure truly reflects invalid performance (i.e., the positive predictive value) depends on the base rate in the context in which the assessment takes place. Therefore, accurate base rate information is needed to guide interpretation of PVT performance. This systematic review and meta-analysis examined the base rate of PVT failure in the clinical population (PROSPERO number: CRD42020164128). PubMed/MEDLINE, Web of Science, and PsychINFO were searched to identify articles published up to November 5, 2021. Main eligibility criteria were a clinical evaluation context and utilization of stand-alone and well-validated PVTs. Of the 457 articles scrutinized for eligibility, 47 were selected for systematic review and meta-analyses. Pooled base rate of PVT failure for all included studies was 16%, 95% CI [14, 19]. High heterogeneity existed among these studies (Cochran's Q = 697.97, p < .001; I2 = 91%; τ2 = 0.08). Subgroup analysis indicated that pooled PVT failure rates varied across clinical context, presence of external incentives, clinical diagnosis, and utilized PVT. Our findings can be used for calculating clinically applied statistics (i.e., positive and negative predictive values, and likelihood ratios) to increase the diagnostic accuracy of performance validity determination in clinical evaluation. Future research is necessary with more detailed recruitment procedures and sample descriptions to further improve the accuracy of the base rate of PVT failure in clinical practice.","PeriodicalId":49754,"journal":{"name":"Neuropsychology Review","volume":" ","pages":"299-319"},"PeriodicalIF":5.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10920461/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10821240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Variability in Hemispheric Functional Segregation Phenotypes: A Review and General Mechanistic Model. 半球功能分离表型的变异性：回顾与一般机制模型

IF 5.8 2区心理学

Neuropsychology Review Pub Date : 2024-03-01 Epub Date: 2022-12-28 DOI: 10.1007/s11065-022-09575-y

Robin Gerrits

引用次数: 0

Coactivation of Autonomic and Central Nervous Systems During Processing of Socially Relevant Information in Autism Spectrum Disorder: A Systematic Review. 自闭症谱系障碍患者在处理社交相关信息时自主神经系统和中枢神经系统的共同激活：系统回顾

IF 5.8 2区心理学

Neuropsychology Review Pub Date : 2024-03-01 Epub Date: 2023-02-27 DOI: 10.1007/s11065-023-09579-2

Suvi Karjalainen, Tuija Aro, Tiina Parviainen

{"title":"Coactivation of Autonomic and Central Nervous Systems During Processing of Socially Relevant Information in Autism Spectrum Disorder: A Systematic Review.","authors":"Suvi Karjalainen, Tuija Aro, Tiina Parviainen","doi":"10.1007/s11065-023-09579-2","DOIUrl":"10.1007/s11065-023-09579-2","url":null,"abstract":"Body-brain interaction provides a novel approach to understand neurodevelopmental conditions such as autism spectrum disorder (ASD). In this systematic review, we analyse the empirical evidence regarding coexisting differences in autonomic (ANS) and central nervous system (CNS) responses to social stimuli between individuals with ASD and typically developing individuals. Moreover, we review evidence of deviations in body-brain interaction during processing of socially relevant information in ASD. We conducted systematic literature searches in PubMed, Medline, PsychInfo, PsychArticles, and Cinahl databases (until 12.1.2022). Studies were included if individuals with ASD were compared with typically developing individuals, study design included processing of social information, and ANS and CNS activity were measured simultaneously. Out of 1892 studies identified based on the titles and abstracts, only six fulfilled the eligibility criteria to be included in synthesis. The quality of these studies was assessed using a quality assessment checklist. The results indicated that individuals with ASD demonstrate atypicalities in ANS and CNS signalling which, however, are context dependent. There were also indications for altered contribution of ANS-CNS interaction in processing of social information in ASD. However, the findings must be considered in the context of several limitations, such as small sample sizes and high variability in (neuro)physiological measures. Indeed, the methodological choices varied considerably, calling for a need for unified guidelines to improve the interpretability of results. We summarize the current experimentally supported understanding of the role of socially relevant body-brain interaction in ASD. Furthermore, we propose developments for future studies to improve incremental knowledge building across studies of ANS-CNS interaction involving individuals with ASD.","PeriodicalId":49754,"journal":{"name":"Neuropsychology Review","volume":" ","pages":"214-231"},"PeriodicalIF":5.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10920494/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10793981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Embodying Time in the Brain: A Multi-Dimensional Neuroimaging Meta-Analysis of 95 Duration Processing Studies. 时间在大脑中的体现：对 95 项时间处理研究的多维神经成像元分析》。

IF 5.8 2区心理学

Neuropsychology Review Pub Date : 2024-03-01 Epub Date: 2023-03-01 DOI: 10.1007/s11065-023-09588-1

Narges Naghibi, Nadia Jahangiri, Reza Khosrowabadi, Claudia R Eickhoff, Simon B Eickhoff, Jennifer T Coull, Masoud Tahmasian

{"title":"Embodying Time in the Brain: A Multi-Dimensional Neuroimaging Meta-Analysis of 95 Duration Processing Studies.","authors":"Narges Naghibi, Nadia Jahangiri, Reza Khosrowabadi, Claudia R Eickhoff, Simon B Eickhoff, Jennifer T Coull, Masoud Tahmasian","doi":"10.1007/s11065-023-09588-1","DOIUrl":"10.1007/s11065-023-09588-1","url":null,"abstract":"Time is an omnipresent aspect of almost everything we experience internally or in the external world. The experience of time occurs through such an extensive set of contextual factors that, after decades of research, a unified understanding of its neural substrates is still elusive. In this study, following the recent best-practice guidelines, we conducted a coordinate-based meta-analysis of 95 carefully-selected neuroimaging papers of duration processing. We categorized the included papers into 14 classes of temporal features according to six categorical dimensions. Then, using the activation likelihood estimation (ALE) technique we investigated the convergent activation patterns of each class with a cluster-level family-wise error correction at p < 0.05. The regions most consistently activated across the various timing contexts were the pre-SMA and bilateral insula, consistent with an embodied theory of timing in which abstract representations of duration are rooted in sensorimotor and interoceptive experience, respectively. Moreover, class-specific patterns of activation could be roughly divided according to whether participants were timing auditory sequential stimuli, which additionally activated the dorsal striatum and SMA-proper, or visual single interval stimuli, which additionally activated the right middle frontal and inferior parietal cortices. We conclude that temporal cognition is so entangled with our everyday experience that timing stereotypically common combinations of stimulus characteristics reactivates the sensorimotor systems with which they were first experienced.","PeriodicalId":49754,"journal":{"name":"Neuropsychology Review","volume":" ","pages":"277-298"},"PeriodicalIF":5.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10920454/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10806520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Association Between Neurocognitive Disorders and Gustatory Dysfunction: A Systematic Review and Meta-Analysis. 神经认知障碍与味觉功能障碍之间的关联：系统回顾与元分析》。

IF 5.8 2区心理学

Neuropsychology Review Pub Date : 2024-03-01 Epub Date: 2023-02-20 DOI: 10.1007/s11065-023-09578-3

Elisa Mantovani, Alice Zanini, Maria Paola Cecchini, Stefano Tamburin

{"title":"The Association Between Neurocognitive Disorders and Gustatory Dysfunction: A Systematic Review and Meta-Analysis.","authors":"Elisa Mantovani, Alice Zanini, Maria Paola Cecchini, Stefano Tamburin","doi":"10.1007/s11065-023-09578-3","DOIUrl":"10.1007/s11065-023-09578-3","url":null,"abstract":"Olfactory and gustatory dysfunction have been reported in mild and major neurocognitive disorders (NCDs), with variable results. While olfactory dysfunction has been consistently explored, reports on gustatory alterations are limited. We systematically reviewed case-control studies evaluating gustatory function in NCDs with various etiologies and different neuropathology. Eighteen studies were included in the systematic review, and eight were included in the meta-analysis. Most studies were on Alzheimer's disease (AD) and Parkinson's disease (PD). Pooled analyses showed worse global taste threshold and identification (sour in particular) scores in AD than controls and worse global, sweet, and sour scores in AD compared to mild cognitive impairment (MCI). PD with MCI showed worse global, sweet, salty, and sour scores than controls and cognitively unimpaired PD. Taste dysfunction was differentially associated with the severity of cognitive deficits. Gustatory dysfunction may represent a potential cross-disease chemosensory biomarker of NCD. Whether gustatory alterations may be a pre-clinical biomarker of NCD requires further studies.","PeriodicalId":49754,"journal":{"name":"Neuropsychology Review","volume":" ","pages":"192-213"},"PeriodicalIF":5.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10920407/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10740786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neuropsychological Changes in Isolated REM Sleep Behavior Disorder: A Systematic Review and Meta-analysis of Cross-sectional and Longitudinal Studies. 孤立快速眼动睡眠行为障碍的神经心理学变化：横断面和纵向研究的系统回顾和元分析》。

IF 5.8 2区心理学

Neuropsychology Review Pub Date : 2024-03-01 Epub Date: 2023-01-02 DOI: 10.1007/s11065-022-09572-1

Caterina Leitner, Giada D'Este, Laura Verga, Shady Rahayel, Samantha Mombelli, Marco Sforza, Francesca Casoni, Marco Zucconi, Luigi Ferini-Strambi, Andrea Galbiati

{"title":"Neuropsychological Changes in Isolated REM Sleep Behavior Disorder: A Systematic Review and Meta-analysis of Cross-sectional and Longitudinal Studies.","authors":"Caterina Leitner, Giada D'Este, Laura Verga, Shady Rahayel, Samantha Mombelli, Marco Sforza, Francesca Casoni, Marco Zucconi, Luigi Ferini-Strambi, Andrea Galbiati","doi":"10.1007/s11065-022-09572-1","DOIUrl":"10.1007/s11065-022-09572-1","url":null,"abstract":"The aim of this meta-analysis is twofold: (a) to assess cognitive impairments in isolated rapid eye movement (REM) sleep behavior disorder (iRBD) patients compared to healthy controls (HC); (b) to quantitatively estimate the risk of developing a neurodegenerative disease in iRBD patients according to baseline cognitive assessment. To address the first aim, cross-sectional studies including polysomnography-confirmed iRBD patients, HC, and reporting neuropsychological testing were included. To address the second aim, longitudinal studies including polysomnography-confirmed iRBD patients, reporting baseline neuropsychological testing for converted and still isolated patients separately were included. The literature search was conducted based on PRISMA guidelines and the protocol was registered at PROSPERO (CRD42021253427). Cross-sectional and longitudinal studies were searched from PubMed, Web of Science, Scopus, and Embase databases. Publication bias and statistical heterogeneity were assessed respectively by funnel plot asymmetry and using I2. Finally, a random-effect model was performed to pool the included studies. 75 cross-sectional (2,398 HC and 2,460 iRBD patients) and 11 longitudinal (495 iRBD patients) studies were selected. Cross-sectional studies showed that iRBD patients performed significantly worse in cognitive screening scores (random-effects (RE) model = -0.69), memory (RE model = -0.64), and executive function (RE model = -0.50) domains compared to HC. The survival analyses conducted for longitudinal studies revealed that lower executive function and language performance, as well as the presence of mild cognitive impairment (MCI), at baseline were associated with an increased risk of conversion at follow-up. Our study underlines the importance of a comprehensive neuropsychological assessment in the context of iRBD.","PeriodicalId":49754,"journal":{"name":"Neuropsychology Review","volume":" ","pages":"41-66"},"PeriodicalIF":5.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10461018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0