Nutrition Metabolism and Cardiovascular Diseases最新文献_第10页

Association between uric acid to high-density lipoprotein cholesterol ratio and peripheral arterial disease in hypertensive patients: A cohort study 高血压患者尿酸与高密度脂蛋白胆固醇比值与外周动脉疾病的关系：一项队列研究

IF 3.3 3区医学

Nutrition Metabolism and Cardiovascular Diseases Pub Date : 2025-03-27 DOI: 10.1016/j.numecd.2025.104026

Congcong Yan , Zaohuang Zhen , Yumeng Shi , Peixu Zhao , Xiaoli Song , Qingling Peng , Xinyi Wang , Wei Zhou , Chao Yu , Tao Wang , Lingjuan Zhu , Huihui Bao , Jianhua Yu , Xiaoshu Cheng

{"title":"Association between uric acid to high-density lipoprotein cholesterol ratio and peripheral arterial disease in hypertensive patients: A cohort study","authors":"Congcong Yan , Zaohuang Zhen , Yumeng Shi , Peixu Zhao , Xiaoli Song , Qingling Peng , Xinyi Wang , Wei Zhou , Chao Yu , Tao Wang , Lingjuan Zhu , Huihui Bao , Jianhua Yu , Xiaoshu Cheng","doi":"10.1016/j.numecd.2025.104026","DOIUrl":"10.1016/j.numecd.2025.104026","url":null,"abstract":"<div><h3>Background and aims</h3><div>Uric acid (UA) to high-density lipoprotein cholesterol (HDL-C) ratio (UHR) is a new indicator of inflammation and metabolism proposed by recent researches. Previous researches have confirmed a positive association between UHR and the risk of cardiovascular death. However, it is undetermined that the association between UHR and peripheral arterial disease (PAD).</div></div><div><h3>Methods and results</h3><div>The research is a prospective cohort study that included a total of 6,867 participants from the Chinese Hypertension Registry Study. 328 participants were identified with PAD during a median follow-up period of 48 months. Multiple logistic regression analysis and smooth curve fitting were applied to explore the association between UHR and PAD among men and women. After adjusting for potential confounders, UHR was positively associated with PAD both in men (HR: 1.27, 95 % CI: 1.07–1.51) and women (HR: 1.45, 95 % CI: 1.19–1.77). Subgroup analyses showed that the association between UHR and PAD remained stable across subgroups of men and women (all P for interaction >0.05).</div></div><div><h3>Conclusions</h3><div>There is a significant positive association between UHR and new-onset PAD in the Chinese hypertensive population both in men and women. An elevated UHR predicted increased risk of PAD.</div></div>","PeriodicalId":49722,"journal":{"name":"Nutrition Metabolism and Cardiovascular Diseases","volume":"35 8","pages":"Article 104026"},"PeriodicalIF":3.3,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between remnant cholesterol and arterial stiffness: Evidence from NHANES 1999–2018 残余胆固醇与动脉硬化之间的关系：来自NHANES 1999-2018的证据。

IF 3.3 3区医学

Nutrition Metabolism and Cardiovascular Diseases Pub Date : 2025-03-27 DOI: 10.1016/j.numecd.2025.104013

Tianjie Lai , Yiyin Liang , Fenglei Guan , Yunxian Chen , Konghe Hu

{"title":"Association between remnant cholesterol and arterial stiffness: Evidence from NHANES 1999–2018","authors":"Tianjie Lai , Yiyin Liang , Fenglei Guan , Yunxian Chen , Konghe Hu","doi":"10.1016/j.numecd.2025.104013","DOIUrl":"10.1016/j.numecd.2025.104013","url":null,"abstract":"<div><h3>Background and aim</h3><div>Remnant cholesterol (RC), an emerging cardiovascular risk factor, has garnered increasing attention in atherosclerotic cardiovascular disease (ASCVD) research, though its relationship with arterial stiffness remains incompletely understood. This study investigated the association between RC and estimated pulse wave velocity (ePWV), a reliable marker of arterial stiffness, with the goal of enhancing our understanding of RC's role in cardiovascular risk assessment.</div></div><div><h3>Methods and results</h3><div>This study utilized the National Health and Nutrition Examination Survey (NHANES) data from 1999 to 2018, including 12,505 participants aged 20 years and above. Weighted linear regression, restricted cubic splines (RCS), and subgroup analyses were used to explore the association between RC levels and ePWV. Analysis revealed a significant positive association between RC levels and ePWV, with participants in the highest RC quintile (Q5) exhibiting substantially elevated ePWV compared to those in the lowest quintile (Q1). Notably, RCS analysis demonstrated a non-linear relationship characterized by a saturation effect (p-nonlinear <0.05). Subgroup analyses indicated stronger associations among specific demographic groups, including individuals under 40 years, females, non-Hispanic whites, and those above the poverty level (all interaction p < 0.05). Furthermore, mediation analysis found that various inflammatory markers such as neutrophil count (NEU), neutrophil-to-lymphocyte ratio (NLR), and monocyte-to-lymphocyte ratio (MLR) played a mediating role in this association.</div></div><div><h3>Conclusion</h3><div>Increased arterial stiffness is associated with higher RC levels, demonstrating a saturation effect at elevated concentrations. This association is partially mediated by NLR, MLR, and NEU, and was stronger among younger, females, non-Hispanic whites, and non-impoverished individuals.</div></div>","PeriodicalId":49722,"journal":{"name":"Nutrition Metabolism and Cardiovascular Diseases","volume":"35 8","pages":"Article 104013"},"PeriodicalIF":3.3,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Causal relationship between serum 25-hydroxyvitamin D and coronary heart disease: A bi-directional two-sample Mendelian randomization study 血清25-羟基维生素D与冠心病的因果关系：一项双向双样本孟德尔随机研究

IF 3.3 3区医学

Nutrition Metabolism and Cardiovascular Diseases Pub Date : 2025-03-26 DOI: 10.1016/j.numecd.2025.104020

Xingping Li , Wenqing Wang , Huanyu Liu , Ronghui Xia , Yang Lin , Guanghui Pan

{"title":"Causal relationship between serum 25-hydroxyvitamin D and coronary heart disease: A bi-directional two-sample Mendelian randomization study","authors":"Xingping Li , Wenqing Wang , Huanyu Liu , Ronghui Xia , Yang Lin , Guanghui Pan","doi":"10.1016/j.numecd.2025.104020","DOIUrl":"10.1016/j.numecd.2025.104020","url":null,"abstract":"<div><h3>Background and aim</h3><div>Coronary heart disease (CHD) is the leading cause of severe cardiovascular events, such as acute myocardial infarction. This study investigates the interaction between serum 25-hydroxyvitamin D (25(OH)D) levels and CHD. However, most current studies are observational, which may introduce bias into the results.</div></div><div><h3>Methods and results</h3><div>We conducted a two-way, two-sample Mendelian randomization study. The CHD sample was drawn from the 2021 population in the FinnGen database (cases: 21,012; controls: 197,780), while the serum 25(OH)D sample was obtained from the 2020 European population in the GWAS Catalog database (417,580 cases). Based on the inverse variance weighted (IVW) results, we found that the risk of CHD decreased with increasing serum 25(OH)D concentrations (P < 0.05), and that higher CHD risk was associated with lower serum 25(OH)D concentrations (P = 0.04).</div></div><div><h3>Conclusions</h3><div>Our study found that increased serum 25(OH)D concentration may serve as a protective factor against CHD. Additionally, we found that CHD can be a risk factor that affects serum 25(OH)D concentrations in humans.</div></div>","PeriodicalId":49722,"journal":{"name":"Nutrition Metabolism and Cardiovascular Diseases","volume":"35 6","pages":"Article 104020"},"PeriodicalIF":3.3,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143804499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serum uric acid fluctuations and cardiovascular outcomes in hospitalized acute heart failure patients 急性心力衰竭住院患者血清尿酸波动与心血管预后

IF 3.3 3区医学

Nutrition Metabolism and Cardiovascular Diseases Pub Date : 2025-03-24 DOI: 10.1016/j.numecd.2025.104025

Guang-Zhi Liao , Jia-Yu Feng , Jing-Xi Wang , Ping Zhou , Chun-Hui He , Xiao-Feng Zhuang , Yan Huang , Qiong Zhou , Mei Zhai , Yu-Hui Zhang , Jian Zhang

{"title":"Serum uric acid fluctuations and cardiovascular outcomes in hospitalized acute heart failure patients","authors":"Guang-Zhi Liao , Jia-Yu Feng , Jing-Xi Wang , Ping Zhou , Chun-Hui He , Xiao-Feng Zhuang , Yan Huang , Qiong Zhou , Mei Zhai , Yu-Hui Zhang , Jian Zhang","doi":"10.1016/j.numecd.2025.104025","DOIUrl":"10.1016/j.numecd.2025.104025","url":null,"abstract":"<div><h3>Background and aims</h3><div>This study examined the association between serum uric acid (SUA) fluctuation patterns during hospitalization in acute heart failure (HF) patients and clinical outcomes, a relationship not fully understood.</div></div><div><h3>Methods and results</h3><div>A cohort of 1403 acute HF patients was enrolled with a median follow-up of 20.5 months. Outcomes assessed included cardiovascular (CV) death and/or heart failure hospitalization (CV death & HHP), CV death alone, and all-cause mortality (ACM). Restricted cubic splines analyzed the relationship between admission SUA levels and outcomes. Patients were categorized based on admission and discharge SUA levels into four groups: 1) Normal SUA at both points (N&N), 2) Elevated SUA at admission, normalized at discharge (H&N), 3) Normal SUA at admission, elevated at discharge (N&H), and 4) Elevated SUA at both points (H&H). Associations between SUA categories and outcomes were assessed using COX multivariate regression analysis. Results showed elevated SUA at admission predicted poor outcomes. However, neither N&H nor H&N groups displayed significant increases in CV death & HHP, CV death, or ACM compared to N&N. The H&H group had the highest risks for CV death (adjusted HR 1.79, 95 % CI 1.10–2.93) and ACM (adjusted HR 1.64, 95 % CI 1.08–2.49), with a non-significant trend towards increased risk of CV death & HHP (adjusted HR 1.79, 95 % CI 0.99–2.93).</div></div><div><h3>Conclusion</h3><div>Persistently elevated SUA levels during hospitalization were independently associated with adverse cardiovascular outcomes and ACM in patients with acute HF, whereas fluctuations in SUA levels did not exhibit a similar association.</div></div>","PeriodicalId":49722,"journal":{"name":"Nutrition Metabolism and Cardiovascular Diseases","volume":"35 6","pages":"Article 104025"},"PeriodicalIF":3.3,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lipid profiles and their association with incident carotid atherosclerosis: A community-based prospective study in Taiwan 血脂及其与颈动脉粥样硬化的关系：台湾一项社区前瞻性研究。

IF 3.3 3区医学

Nutrition Metabolism and Cardiovascular Diseases Pub Date : 2025-03-21 DOI: 10.1016/j.numecd.2025.104023

Tzu-Wei Wu , Chao-Liang Chou , Chun-Chieh Liu , Chuen-Fei Chen , Chun-Fang Cheng , Li-Yu Wang

{"title":"Lipid profiles and their association with incident carotid atherosclerosis: A community-based prospective study in Taiwan","authors":"Tzu-Wei Wu , Chao-Liang Chou , Chun-Chieh Liu , Chuen-Fei Chen , Chun-Fang Cheng , Li-Yu Wang","doi":"10.1016/j.numecd.2025.104023","DOIUrl":"10.1016/j.numecd.2025.104023","url":null,"abstract":"<div><h3>Background and aims</h3><div>Dyslipidemia, characterized by abnormal blood lipid levels, contributes to atherosclerosis, a condition involving arterial plaque buildup and cardiovascular events. While LDL-C and LDL-to-HDL-C ratios are established atherosclerosis predictors, the role of non-HDL-C is less explored.</div></div><div><h3>Methods and results</h3><div>A cohort of 1062 participants without carotid plaque at baseline was analyzed over a 4.0-year follow-up. Age-specific incidence rates were calculated, and baseline characteristics of those who developed plaques were compared using logistic regression and area under the ROC curve (AUROC) analysis to evaluate predictive models. Carotid plaques developed in 284 participants (87 males, 197 females). Incidence rates increased with age, reaching 41.2 % in females and 60.0 % in males aged 70–74 years. Participants with plaques were older (58.2 vs. 55.4 years, p < 0.0001), had higher BMI, blood pressure, and lipid markers, and were more likely to be male, hypertensive, or hyperlipidemic. Logistic regression identified age (OR 1.26 per 5 years), BMI (OR 1.23 per 5 kg/m<sup>2</sup>), LDL-C (OR 1.07 per 10 mg/dL), and LDL-to-HDL-C ratio (OR 1.41) as significant predictors, with HDL-C offering a protective effect. Models incorporating lipid ratios (non-HDL-to-HDL-C or LDL-to-HDL-C) showed similar predictive power (AUROC 0.636).</div></div><div><h3>Conclusion</h3><div>Carotid plaque progression correlates with age, male sex, elevated BMI, hypertension, and adverse lipid profiles. Lipid ratios and age are consistent predictors, with HDL-C demonstrating protective effects. Comparable AUROC values across models underscore the value of lipid ratios for assessing atherosclerosis risk.</div></div>","PeriodicalId":49722,"journal":{"name":"Nutrition Metabolism and Cardiovascular Diseases","volume":"35 6","pages":"Article 104023"},"PeriodicalIF":3.3,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143804526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative association of MAFLD/MASLD and Subtypes with Cardiovascular Diseases Outcomes MAFLD/MASLD和亚型与心血管疾病结果的比较关联。

IF 3.3 3区医学

Nutrition Metabolism and Cardiovascular Diseases Pub Date : 2025-03-19 DOI: 10.1016/j.numecd.2025.104024

Huizhen Jin , Zhuoshuai Liang , Xinmeng Hu , Xiaoyang Li , Zhantong Liu , Yichun Qiao , Yi Cheng , Hanxin Yao , Yawen Liu

{"title":"Comparative association of MAFLD/MASLD and Subtypes with Cardiovascular Diseases Outcomes","authors":"Huizhen Jin , Zhuoshuai Liang , Xinmeng Hu , Xiaoyang Li , Zhantong Liu , Yichun Qiao , Yi Cheng , Hanxin Yao , Yawen Liu","doi":"10.1016/j.numecd.2025.104024","DOIUrl":"10.1016/j.numecd.2025.104024","url":null,"abstract":"<div><h3>Background and aims</h3><div>Metabolic dysfunction-associated steatotic liver disease (MASLD) acts as an alternative for demarcating metabolic dysfunction-associated fatty liver disease (MAFLD). This study aimed to investigate the factors that significantly influence the relationship between MAFLD and MASLD in relation to the incidence of major cardiovascular outcomes.</div></div><div><h3>Methods and results</h3><div>A total of 340,998 participants in the UK Biobank study were included. Multivariable Cox proportional hazards models were used to estimate the effect of MAFLD and MASLD on the outcomes of cardiovascular diseases (CVDs) (coronary artery disease, stroke, heart failure, and CVD-related death) with hazard ratios (HRs) and 95 % confidence intervals (CIs). A total of 126,077 (36.97 %) participants had MAFLD and 97,418 (28.57 %) had MASLD. Over a median follow-up of 13.5 years (interquartile range 12.6–14.2), there were 41,548 new events of CVDs recorded. MAFLD (HR = 1.52; 95 % CI: 1.49–1.55) and MASLD (HR = 1.42; 95 % CI: 1.39–1.45) were associated with high risks of CVDs. Among the subtypes of MAFLD and steatotic liver disease (SLD), MAFLD diabetes subtype (HR = 2.26; 95 % CI: 2.17–2.35) and alcohol-associated liver disease (ALD) (HR = 1.65; 95 % CI: 1.55–1.76) exhibited the highest risk of CVDs. MAFLD overweight without MD subtype were not associated with CVDs. The effect of MAFLD on the CVD outcomes was consistent regardless of the presence of MASLD.</div></div><div><h3>Conclusion</h3><div>The metabolic health status and alcohol consumption function as more critical factors than obesity in assessing CVD outcomes in participants with MAFLD or MASLD.</div></div>","PeriodicalId":49722,"journal":{"name":"Nutrition Metabolism and Cardiovascular Diseases","volume":"35 6","pages":"Article 104024"},"PeriodicalIF":3.3,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Moderate alcohol consumption does not necessarily equate to cardiovascular protection 适度饮酒并不一定等同于心血管保护。

IF 3.3 3区医学

Nutrition Metabolism and Cardiovascular Diseases Pub Date : 2025-03-18 DOI: 10.1016/j.numecd.2025.104022

Stephan Peronard Mayntz , Kasper Emil Rosenbech

引用次数: 0

Strawberries modestly improve cognition and cardiovascular health in older adults 草莓适度改善老年人的认知和心血管健康。

IF 3.3 3区医学

Nutrition Metabolism and Cardiovascular Diseases Pub Date : 2025-03-18 DOI: 10.1016/j.numecd.2025.104018

Kristin Delaney, Michelle Tsang, Mark Kern, Vernon Uganiza Rayo, Nathaniel Jason, Mee Young Hong, Changqi Liu, Shirin Hooshmand

{"title":"Strawberries modestly improve cognition and cardiovascular health in older adults","authors":"Kristin Delaney, Michelle Tsang, Mark Kern, Vernon Uganiza Rayo, Nathaniel Jason, Mee Young Hong, Changqi Liu, Shirin Hooshmand","doi":"10.1016/j.numecd.2025.104018","DOIUrl":"10.1016/j.numecd.2025.104018","url":null,"abstract":"<div><h3>Background and aims</h3><div>Strawberry consumption may aid in improving cognitive function and cardiovascular health given their nutrient composition and antioxidant capacities. We hypothesized that 2 cups of fresh strawberries per day provided as a freeze-dried strawberry powder (26 g/d) may improve cognitive performance and cardiovascular health relative to a control.</div></div><div><h3>Methods and results</h3><div>Using a randomized, crossover, double-blind, placebo-controlled clinical trial, 35 healthy older adults (17 women, 18 men, age 72 ± 6 years, BMI 26.4 ± 3.9 kg/m<sup>2</sup>) consumed 26 g of freeze-dried strawberry powder (strawberry) and a control powder (control) daily for 8 weeks each with a 4-week washout period. Strawberry supplementation was expected to improve cardiometabolic health parameters, and cognitive performance measured with the National Institutes of Health Toolbox. Processing speed (p < 0.001) improved during the strawberry phase and episodic memory (p = 0.002) improved during the control phase. For cardiovascular measures, strawberry consumption reduced systolic blood pressure (p = 0.044) and a significant main effect of time for reduced waist circumference (p = 0.043) was detected. Serum triglycerides increased in the control group (p = 0.012) but not after consuming strawberries. Total antioxidant capacity significantly decreased during the control phase (p = 0.032) and significantly increased with strawberry consumption (p = 0.047).</div></div><div><h3>Conclusion</h3><div>This study demonstrated that 26 g of freeze dried strawberries improve cognitive processing speed, lower systolic blood pressure, and increase antioxidant capacity, potentially promoting cognitive function and improving cardiovascular risk factors in cognitively healthy individuals. <em>Clinical Trial Registry: NCT04786665.</em></div></div>","PeriodicalId":49722,"journal":{"name":"Nutrition Metabolism and Cardiovascular Diseases","volume":"35 8","pages":"Article 104018"},"PeriodicalIF":3.3,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Response to the letter on the article: Effect of moderate alcohol intake on blood apolipoproteins concentrations: A meta-analysis of human intervention studies 对文章《适度饮酒对血液载脂蛋白浓度的影响：一项人为干预研究的荟萃分析》的回复。

IF 3.3 3区医学

Nutrition Metabolism and Cardiovascular Diseases Pub Date : 2025-03-17 DOI: 10.1016/j.numecd.2025.104021

Anila Khatiwada , Anju Rawal , Gabriele Berg-Beckhoff , Trine Levring Wilkens

引用次数: 0

Effects of whole-body vibration exercise on cardiorespiratory fitness, muscular strength and body fat in women with overweight and obesity: A randomized pilot study 全身振动运动对超重和肥胖女性心肺健康、肌肉力量和体脂的影响：一项随机先导研究

IF 3.3 3区医学

Nutrition Metabolism and Cardiovascular Diseases Pub Date : 2025-03-17 DOI: 10.1016/j.numecd.2025.104019

Seongmin Kim , Serim Cho , SoJung Lee

{"title":"Effects of whole-body vibration exercise on cardiorespiratory fitness, muscular strength and body fat in women with overweight and obesity: A randomized pilot study","authors":"Seongmin Kim , Serim Cho , SoJung Lee","doi":"10.1016/j.numecd.2025.104019","DOIUrl":"10.1016/j.numecd.2025.104019","url":null,"abstract":"<div><h3>Background and aim</h3><div>Whole-body vibration (WBV) exercise has been acknowledged as an alternative exercise method for improving functional capacity. We examined the effects of an 8-week WBV exercise on cardiorespiratory fitness (CRF), muscular strength (MS) and body composition in young women.</div></div><div><h3>Methods and results</h3><div>Twenty-six inactive women with overweight and obesity (age: 30.2 ± 8.0 years, BMI: 25.7 ± 1.9 kg/m<sup>2</sup>) were randomly assigned to WBV exercise (<em>n</em> = 13) or control (<em>n</em> = 13) groups. The WBV exercise group participated in static and dynamic exercises on a vibration platform (3 sessions/week, 60 min/session) for 8 weeks. The control group maintained their usual lifestyle without structured exercise. CRF was measured by VO<sub>2peak</sub> and MS index was measured by the 1-RM (kg) for the chest and leg press, expressed relative to body weight (kg). Body composition was assessed by bioelectrical impedance analysis. Of the 26 participants randomized, 23 participants (13 WBV and 10 controls) completed the intervention, with 94.2 % exercise adherence rate. A two-way repeated measures ANOVA revealed that the WBV exercise group had reductions (<em>p</em> < 0.05 for all) in body weight (−2.4 kg), BMI (−0.9 kg/m<sup>2</sup>), body fat (−2.8 kg) and waist circumference (−3.5 cm) compared to the control group. VO<sub>2peak</sub> (pre: 27.9 ± 4.8 vs. post: 30.7 ± 4.4 ml/kg/min, <em>p</em> = 0.005) and MS index (pre: 2.0 ± 0.4 vs. post: 3.0 ± 0.7, <em>p</em> < 0.001) increased in the WBV exercise group, but not in the control group.</div></div><div><h3>Conclusion</h3><div>WBV exercise is effective for improving fitness and body fat in young women with overweight and obesity.</div></div>","PeriodicalId":49722,"journal":{"name":"Nutrition Metabolism and Cardiovascular Diseases","volume":"35 6","pages":"Article 104019"},"PeriodicalIF":3.3,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0