The American journal of medical sciences and pharmaceutical research最新文献

{"title":"SURGICAL TREATMENT OF FEMORAL SHAFT FRACTURES IN POLYTRAUMATIZED PATIENTS","authors":"Melissa Alves Aires Marques, Bianca Gabriella de Oliveira, Ábila Dutra Oliveira, Ana Teresa Bastos Tinoco, Kleina Da Silva Damas, Laís Ferreira Camacho, Lívia Piñeiro Nery, Matheus Velasco Brito Gonçalves","doi":"10.37547/tajmspr/volume05issue10-09","DOIUrl":"https://doi.org/10.37547/tajmspr/volume05issue10-09","url":null,"abstract":"Fractures of the femur are common, usually serious and are the result of high-energyaccidents. They can be associated with involvement of other organs, causing deformities and sequelae for the patient, due to immediate or late complications. Anatomical reduction and stable internal fixation are essential in order to achieve the treatment objectives in patients with good bone quality. Treatment is eminently surgical as it allows early rehabilitation and reduces the risk of systemic complications. There are numerous therapeutic options, but osteosynthesis with an intramedullary plate and nail stands out. However, some factors influence the choice of the type of surgical intervention to be performed, such as hospital resources, availability of suitable material for the procedure, trained staff and availability of an image intensifier.","PeriodicalId":494509,"journal":{"name":"The American journal of medical sciences and pharmaceutical research","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136246724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DESCRIPTION OF THE ONE FLAP TECHNIQUE FOR THE SURGICAL TREATMENT OF SYNDACTYLY","authors":"Leandro Azevedo De Figueiredo, Bianca Gabriella De Oliveira, Pedro Hemerly Figueiredo, Marcella Rodrigues Costa Simoes","doi":"10.37547/tajmspr/volume05issue10-08","DOIUrl":"https://doi.org/10.37547/tajmspr/volume05issue10-08","url":null,"abstract":"Syndactyly is a congenital defect of the fingers or toes that can cause aesthetic and functional problems. In this condition there is a defect in the separation of the parts, according to the Swanson Classification, determined between the sixth and eighth week of intrauterine life and representing approximately 20% of all hand malformations. This pathology is the second most common congenital anomaly of the hand and has an incidence of 1:2000 to 3000 live births. It is one of the most heterogeneous deformities known in the literature, with unilateral, bilateral, symmetrical and asymmetrical variations. It occurs twice as often in boys. The aim of this study is to describe a new skin flap design for the treatment of syndactyly. This is a descriptive study, as it aims to detail the surgical technique using different processes for the treatment of simple or complex, incomplete or complete syndactyly.The study maintains the principles of the digital commissure reconstruction approach, adequate skin coverage and reconstruction of the nail bed, presenting a new flap associated with polypropylene coverage, solving the disadvantages of using a skin graft, such as deformities at the recipient site and morbidity of the donor area.","PeriodicalId":494509,"journal":{"name":"The American journal of medical sciences and pharmaceutical research","volume":"141 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136246609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"REHABILITATION OF PATIENTS AFTER SURGERY WITH POST-COVID ASEPTIC NECROSIS OF THE FEMORAL HEAD","authors":"Asilova S.U., Mirzaev A., Ernazarov Zh.G., Nazarova F. N., Nazirova M.U., Umarova G.Sh.","doi":"10.37547/tajmspr/volume05issue05-14","DOIUrl":"https://doi.org/10.37547/tajmspr/volume05issue05-14","url":null,"abstract":"We carried out rehabilitation of patients after surgery with post-COVID aseptic necrosis of the femoral head according to the method developed by us in 49 patients. The patients were divided into 2 groups: the main group of 25 and the control group of 24 patients. The main group underwent rehabilitation developed by us, the control group by the traditional method. The results of rehabilitation were checked by the Coordination-speed test, the test parameters before the operation to the main group of the operated leg and after the operation, the difference in the number of movements in 10 seconds was estimated. when performing the test with an operated and non-operated leg, at the same time, the hip abduction index increased to the greatest extent after the operation. The data of the coordination test showed that the control group before the operation on the operated leg (retraction, step forward, backward) was within 9.0 m. These indicators after the operation on the 3rd- 5th day became 8.5 m, on the 14th day they were noted within 9.4 m . The data of the coordination test were noted before the operation to the main group on the operated leg (retraction, step forward, backward) was within 9.4 m. These indicators after the operation on the 3rd- 5th day became 9.8 m, on the 14th day they were noted within 12.4 m. The data obtained shows that the result in all parameters is better in the main group than in the control group, and the difference in the dynamics of indicators is clearly visible. Conducting better postoperative rehabilitation shows the performance of the gluteal muscles, as it is most important in terms of prevention of dislocations of endoprostheses. Thus, the method of stage-by-stage rehabilitation developed by us, post-COVID femoral head aseptic necrosis, contributes to improving the results of treatment. A differentiated approach to the rehabilitation of patients with post-COVID femoral head aseptic necrosis has reduced the duration of rehabilitation and disability.","PeriodicalId":494509,"journal":{"name":"The American journal of medical sciences and pharmaceutical research","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134992642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"GLUTATHIONE: THE MASTER ANTIOXIDANT AND ITS ROLE IN HEALTH AND DISEASE","authors":"Dr. Saibal Sonkusare, Dr. Abhijeet Chaturvedi","doi":"10.37547/tajmspr/volume05issue05-01","DOIUrl":"https://doi.org/10.37547/tajmspr/volume05issue05-01","url":null,"abstract":"Glutathione is a tripeptide composed of three amino acids: glutamate, cysteine, and glycine. It plays a crucial role in protecting cells against oxidative stress by acting as an antioxidant. Glutathione also has other important functions, such as detoxification, immune system modulation, and regulation of cellular proliferation and apoptosis. Decreased levels of glutathione have been associated with various diseases, including cancer, Alzheimer's disease, and Parkinson's disease. This article reviews the current literature on glutathione, its role as an antioxidant and other functions, and its association with various diseases.","PeriodicalId":494509,"journal":{"name":"The American journal of medical sciences and pharmaceutical research","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135288360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}