{"title":"GLUTATHIONE: THE MASTER ANTIOXIDANT AND ITS ROLE IN HEALTH AND DISEASE","authors":"Dr. Saibal Sonkusare, Dr. Abhijeet Chaturvedi","doi":"10.37547/tajmspr/volume05issue05-01","DOIUrl":null,"url":null,"abstract":"Glutathione is a tripeptide composed of three amino acids: glutamate, cysteine, and glycine. It plays a crucial role in protecting cells against oxidative stress by acting as an antioxidant. Glutathione also has other important functions, such as detoxification, immune system modulation, and regulation of cellular proliferation and apoptosis. Decreased levels of glutathione have been associated with various diseases, including cancer, Alzheimer's disease, and Parkinson's disease. This article reviews the current literature on glutathione, its role as an antioxidant and other functions, and its association with various diseases.","PeriodicalId":494509,"journal":{"name":"The American journal of medical sciences and pharmaceutical research","volume":"13 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The American journal of medical sciences and pharmaceutical research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.37547/tajmspr/volume05issue05-01","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Glutathione is a tripeptide composed of three amino acids: glutamate, cysteine, and glycine. It plays a crucial role in protecting cells against oxidative stress by acting as an antioxidant. Glutathione also has other important functions, such as detoxification, immune system modulation, and regulation of cellular proliferation and apoptosis. Decreased levels of glutathione have been associated with various diseases, including cancer, Alzheimer's disease, and Parkinson's disease. This article reviews the current literature on glutathione, its role as an antioxidant and other functions, and its association with various diseases.