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Taiwanese Journal of Obstetrics & Gynecology最新文献

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OHVIRA syndrome: A case report treated with delayed diagnosis and multidisciplinary approaches OHVIRA综合征：延迟诊断和多学科方法治疗1例报告
IF 2 4区 医学
Taiwanese Journal of Obstetrics & Gynecology Pub Date : 2025-07-01 DOI: 10.1016/j.tjog.2024.08.014
Emrullah Akay, Alime Dilayda Uzun Gül
{"title":"OHVIRA syndrome: A case report treated with delayed diagnosis and multidisciplinary approaches","authors":"Emrullah Akay,&nbsp;Alime Dilayda Uzun Gül","doi":"10.1016/j.tjog.2024.08.014","DOIUrl":"10.1016/j.tjog.2024.08.014","url":null,"abstract":"<div><h3>Objective</h3><div>OHVIRA syndrome is a rare condition involving genitourinary anomalies, where early diagnosis and intervention can reduce the need for complex treatment processes and surgical interventions.</div></div><div><h3>Case report</h3><div>A 42-year-old female patient was diagnosed with OHVIRA syndrome and treated with antibiotic therapy and vaginal septectomy; however, due to elevated CRP levels and severe abdominal pain, a hysterectomy was performed. Post-surgery, the patient showed improvement and was discharged.</div></div><div><h3>Conclusion</h3><div>OHVIRA syndrome is a rare congenital anomaly that manifests with symptoms during adolescence. The diagnostic and treatment process can be challenging and may involve various complications. Early diagnosis and minimally invasive surgery alleviate symptoms and preserve reproductive potential. This case report highlights the multidisciplinary management of OHVIRA syndrome and the complexities of the treatment processes.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 4","pages":"Pages 693-699"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144518501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is the far-advanced endometrial cancer curable? 晚期子宫内膜癌可以治愈吗？
IF 2 4区 医学
Taiwanese Journal of Obstetrics & Gynecology Pub Date : 2025-07-01 DOI: 10.1016/j.tjog.2025.04.005
Peng-Hui Wang, Chia-Hao Liu, Wen-Shiung Liou
{"title":"Is the far-advanced endometrial cancer curable?","authors":"Peng-Hui Wang,&nbsp;Chia-Hao Liu,&nbsp;Wen-Shiung Liou","doi":"10.1016/j.tjog.2025.04.005","DOIUrl":"10.1016/j.tjog.2025.04.005","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 4","pages":"Pages 596-598"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144518682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent advances in cervical cancer treatment: Innovations from early-stage to advanced disease 宫颈癌治疗的最新进展：从早期到晚期疾病的创新
IF 2 4区 医学
Taiwanese Journal of Obstetrics & Gynecology Pub Date : 2025-07-01 DOI: 10.1016/j.tjog.2025.04.006
Hao Lin , Chen-Hsuan Wu , Hung-Chun Fu , Yu-Che Ou
{"title":"Recent advances in cervical cancer treatment: Innovations from early-stage to advanced disease","authors":"Hao Lin ,&nbsp;Chen-Hsuan Wu ,&nbsp;Hung-Chun Fu ,&nbsp;Yu-Che Ou","doi":"10.1016/j.tjog.2025.04.006","DOIUrl":"10.1016/j.tjog.2025.04.006","url":null,"abstract":"<div><div>This article provides a comprehensive review of recent advancements in cervical cancer treatment, highlighting significant breakthroughs in managing the disease at various stages. Traditional treatments, such as radical surgery for early-stage disease and concurrent chemoradiation (CCRT) for advanced stages, have dominated clinical practice for decades. However, recent phase III studies have challenged these norms, leading to new treatment paradigms. For early-stage cervical cancer, the LACC trial revealed that minimally invasive surgery results in poorer outcomes compared to open surgery, prompting updates in clinical guidelines. Additionally, the SHAPE trial suggested that simple hysterectomy might be sufficient for low-risk cases, offering comparable oncological outcomes with fewer complications than radical hysterectomy. In locally advanced diseases, the INTERLACE study demonstrated the benefits of adding short-course induction chemotherapy before CCRT, improving progression-free and overall survival rates. Immunotherapy has also emerged as a promising treatment, with trials like KEYNOTE-A18 showing that pembrolizumab combined with CCRT enhances progression-free survival in high-risk cases. For recurrent or metastatic cervical cancer, the KEYNOTE-826 trial highlighted the efficacy of pembrolizumab with chemotherapy, showing significant survival benefits across various patient subgroups. The antibody–drug conjugates tisotumab vedotin and trastuzumab deruxtecan also showed promising results, even if patients have progressed after multiple lines of treatment including immunotherapy. These advances represent a shift towards more personalized and effective treatments for cervical cancer, improving outcomes for patients across different disease statuses.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 4","pages":"Pages 608-615"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144518685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Detection of a rare maternal 6q27 microduplication in a fetus with no phenotypic abnormalities 在无表型异常的胎儿中检测罕见的母体6q27微重复
IF 2 4区 医学
Taiwanese Journal of Obstetrics & Gynecology Pub Date : 2025-07-01 DOI: 10.1016/j.tjog.2024.11.013
Ji Wu , Weihua Tian , Tou Tou , Shuqin Xu
{"title":"Detection of a rare maternal 6q27 microduplication in a fetus with no phenotypic abnormalities","authors":"Ji Wu ,&nbsp;Weihua Tian ,&nbsp;Tou Tou ,&nbsp;Shuqin Xu","doi":"10.1016/j.tjog.2024.11.013","DOIUrl":"10.1016/j.tjog.2024.11.013","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 4","pages":"Pages 745-746"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144518678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abnormal methylation of ST8SIA4 in low-motility sperm: A genome-wide identification approach 低活力精子中ST8SIA4异常甲基化：全基因组鉴定方法
IF 2 4区 医学
Taiwanese Journal of Obstetrics & Gynecology Pub Date : 2025-07-01 DOI: 10.1016/j.tjog.2025.02.005
Chia-Ching Chang , Li-Chun Liu , Yu-Ting Chou , Chia-Wei Chen , Chih-Chi Guo , Chying-Chyuan Chan , Ta-Jen Lin , Ching-Hui Chen , Ming-Tzeung Chung
{"title":"Abnormal methylation of ST8SIA4 in low-motility sperm: A genome-wide identification approach","authors":"Chia-Ching Chang ,&nbsp;Li-Chun Liu ,&nbsp;Yu-Ting Chou ,&nbsp;Chia-Wei Chen ,&nbsp;Chih-Chi Guo ,&nbsp;Chying-Chyuan Chan ,&nbsp;Ta-Jen Lin ,&nbsp;Ching-Hui Chen ,&nbsp;Ming-Tzeung Chung","doi":"10.1016/j.tjog.2025.02.005","DOIUrl":"10.1016/j.tjog.2025.02.005","url":null,"abstract":"<div><h3>Objective</h3><div>To identify abnormally methylated genes associated with low motility sperm and to validate the DNA methylation level of our candidate gene ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 (ST8SIA4) in low-motility sperm.</div></div><div><h3>Materials and methods</h3><div>The MethylationEPIC Array which can measure methylation at &gt;850,000 CpG sites and a pooled DNA strategy were used to investigate the genome-wide methylation profiles in sperm with different motility. A total of seventy semen samples, including 52 normozoospermic controls and 18 asthenozoospermic samples, were used to examine the quantitative DNA methylation level of ST8SIA4 gene.</div></div><div><h3>Results</h3><div>Using the gene function classification in the DAVID Bioinformatics Resources, we found that the abnormally methylated genes in the asthenozoospermia samples were predominantly associated with transcription regulation, metal binding, microtubules, meiosis, palmitate, zinc, and developmental proteins. Interestingly, these glycosyltransferase-associated genes were all hypomethylated in asthenozoospermia, except for ST8SIA4.</div></div><div><h3>Conclusion</h3><div>The promoter methylation level of ST8SIA4 was significantly higher in sperm samples with low motility compared with normal control samples.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 4","pages":"Pages 650-654"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144518364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is the less the better for early-stage low-risk cervical cancer? 早期低风险子宫颈癌越少越好吗？
IF 2 4区 医学
Taiwanese Journal of Obstetrics & Gynecology Pub Date : 2025-07-01 DOI: 10.1016/j.tjog.2025.05.013
Peng-Hui Wang, Wei-Ting Chao, Jae-Weon Kim
{"title":"Is the less the better for early-stage low-risk cervical cancer?","authors":"Peng-Hui Wang,&nbsp;Wei-Ting Chao,&nbsp;Jae-Weon Kim","doi":"10.1016/j.tjog.2025.05.013","DOIUrl":"10.1016/j.tjog.2025.05.013","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 4","pages":"Pages 602-604"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144518684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prenatal diagnosis and genetic counselling of a paternal inherited GLI3 frameshift deletion in a Chinese family 一个中国家庭父系遗传性GLI3移码缺失的产前诊断和遗传咨询
IF 2 4区 医学
Taiwanese Journal of Obstetrics & Gynecology Pub Date : 2025-07-01 DOI: 10.1016/j.tjog.2024.10.025
Ru Mei , Wenjuan Tang , Yanhong Peng
{"title":"Prenatal diagnosis and genetic counselling of a paternal inherited GLI3 frameshift deletion in a Chinese family","authors":"Ru Mei ,&nbsp;Wenjuan Tang ,&nbsp;Yanhong Peng","doi":"10.1016/j.tjog.2024.10.025","DOIUrl":"10.1016/j.tjog.2024.10.025","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 4","pages":"Pages 747-748"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144518446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
“Armadillo” sign as a new prenatal ultrasound clue for Pierre Robin sequence “犰狳”标志作为皮埃尔·罗宾序列的产前超声新线索
IF 2 4区 医学
Taiwanese Journal of Obstetrics & Gynecology Pub Date : 2025-07-01 DOI: 10.1016/j.tjog.2024.12.031
Tze-Yi Yang , Philip Kuo-Ting Chen , Ksenia Olisova , Hsuan Ko , Tung-Yao Chang
{"title":"“Armadillo” sign as a new prenatal ultrasound clue for Pierre Robin sequence","authors":"Tze-Yi Yang ,&nbsp;Philip Kuo-Ting Chen ,&nbsp;Ksenia Olisova ,&nbsp;Hsuan Ko ,&nbsp;Tung-Yao Chang","doi":"10.1016/j.tjog.2024.12.031","DOIUrl":"10.1016/j.tjog.2024.12.031","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 4","pages":"Pages 749-751"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144518447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post-laparoscopic shoulder-tip pain (STP) 腹腔镜后肩尖疼痛（STP）
IF 2 4区 医学
Taiwanese Journal of Obstetrics & Gynecology Pub Date : 2025-07-01 DOI: 10.1016/j.tjog.2025.05.001
Peng-Hui Wang, Szu-Ting Yang, Wen-Ling Lee
{"title":"Post-laparoscopic shoulder-tip pain (STP)","authors":"Peng-Hui Wang,&nbsp;Szu-Ting Yang,&nbsp;Wen-Ling Lee","doi":"10.1016/j.tjog.2025.05.001","DOIUrl":"10.1016/j.tjog.2025.05.001","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 4","pages":"Pages 589-591"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144518680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recurrent cesarean scar pregnancy successfully managed by laparoscopy: Case report and current trend 腹腔镜成功治疗复发性剖宫产瘢痕妊娠：病例报告及趋势
IF 2 4区 医学
Taiwanese Journal of Obstetrics & Gynecology Pub Date : 2025-07-01 DOI: 10.1016/j.tjog.2025.04.011
Jing Wang Lin , Hsien Yung Lai , Jen Yu Tseng , Peng-Hui Wang
{"title":"Recurrent cesarean scar pregnancy successfully managed by laparoscopy: Case report and current trend","authors":"Jing Wang Lin ,&nbsp;Hsien Yung Lai ,&nbsp;Jen Yu Tseng ,&nbsp;Peng-Hui Wang","doi":"10.1016/j.tjog.2025.04.011","DOIUrl":"10.1016/j.tjog.2025.04.011","url":null,"abstract":"<div><h3>Objective</h3><div>Termination of cesarean scar pregnancy (CSP) is the recommended treatment of choice; however, how to select an appropriate treatment is often a dilemma, particularly for the women with repeated CSP (RCSP).</div></div><div><h3>Case report</h3><div>A 37-year-old woman with two previous cesarean deliveries and one previous CSP was diagnosed as RCSP at 5 + 4 gestational weeks. An early and accurate diagnosis of RCSP following laparoscopic excision and repairment of defect had obtained the uneventful outcome.</div></div><div><h3>Conclusion</h3><div>Although there are many strategies suitable for women with CSP, laparoscopic resection and primary repair may be a good choice, not only for definite removal but also for reconstruction of cesarean scar defect.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 4","pages":"Pages 711-715"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144518354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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