Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery最新文献

{"title":"The potential risks of artificial intelligence in cardiovascular care.","authors":"Hakan Göçer, Ahmet Barış Durukan","doi":"10.5606/tgkdc.dergisi.2025.26912","DOIUrl":"10.5606/tgkdc.dergisi.2025.26912","url":null,"abstract":"","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":"33 2","pages":"262-264"},"PeriodicalIF":0.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188959/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors determining early mortality in ischemic mitral regurgitation surgery.","authors":"Batuhan Yazıcı, Zinar Apaydın, Mustafa Can Kaplan, Alkım Ateşli Yazıcı, Barış Timur, Kübra Gözaçık, Elif Güneysu, Soner Sanioğlu","doi":"10.5606/tgkdc.dergisi.2025.27206","DOIUrl":"10.5606/tgkdc.dergisi.2025.27206","url":null,"abstract":"<p><strong>Background: </strong>This study aims to identify the causes of early mortality in patients undergoing mitral valve surgery performed in combination with coronary artery bypass grafting for the treatment of ischemic mitral regurgitation.</p><p><strong>Methods: </strong>Between January 2017 and January 2023, a total of 411 patients (272 males, 139 females; mean age: 63.1±9.1 years; range, 32 to 92 years) who underwent coronary artery bypass grafting and mitral valve surgery due to ischemic mitral regurgitation were retrospectively analyzed. The primary outcome measure of the study was in-hospital mortality. The patients were divided into two groups as those with and without in-hospital mortality. Variables affecting mortality were identified.</p><p><strong>Results: </strong>In-hospital mortality was observed in 13.6% (n=56) of the patients. Elective surgery was performed in 308 patients (74.9%), while priority surgery was performed in 103 patients (25.1%). Mortality rate was 9.1% in elective cases and 27.1% in priority cases. Independent risk factors for mortality included age (p=0.001), female sex (p<0.001), priority surgery (p=0.005), low left ventricular ejection fraction (p=0.005), high creatinine levels (p=0.002), the presence of extracardiac arteriopathy (p=0.042), and prolonged cardiopulmonary bypass time (p<0.001). In priority cases, a waiting period of ≤9 days was associated with higher mortality (area under the curve: 0.781, sensitivity: 75%, specificity: 72%, p<0.001).</p><p><strong>Conclusion: </strong>A comprehensive preoperative evaluation is crucial for optimizing outcomes in patients with ischemic mitral regurgitation. In high-risk cases, the use of less invasive approaches, such as percutaneous interventions, can be considered potential alternatives. In priority cases, if hemodynamic stability can be achieved, waiting nine days after the index event before performing surgical intervention may significantly reduce perioperative and in-hospital mortality rates.</p>","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":"33 2","pages":"154-164"},"PeriodicalIF":0.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of preoperative balloon atrial septostomy and intraoperative parameters on neurodevelopmental scoring in neonates operated for transposition of the great artery.","authors":"Yiğit Kılıç, Şenay Güven Baysal, Özlem Gül, Bedri Aldudak","doi":"10.5606/tgkdc.dergisi.2025.26431","DOIUrl":"10.5606/tgkdc.dergisi.2025.26431","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to investigate the effect of preoperative balloon atrial septostomy and intraoperative parameters on neurodevelopmental outcomes in neonates operated for transposition of the great arteries.</p><p><strong>Methods: </strong>Between February 2018 and March 2022, a total of 60 patients (49 male, 11 female; mean age, 23.5±8.8 days; range, 2 to 106 days) who were operated with a diagnosis of simple transposition of the great arteries and discharged uneventfully were included. Preoperative balloon atrial septostomy was performed in 33 patients (BAS+ group), while 27 patients (BAS- group) did not undergo the procedure. Finally, 13 patients from the septostomy group and 12 patients from the non-septostomy group were available for follow-up. Neurodevelopment in infants was assessed using the 3^rd edition of the Bayley Scales of Infant and Toddler Development (Bayley-III) scoring.</p><p><strong>Results: </strong>The mean cognitive, language, and motor composite scores were 85.00±11.73, 89.62±12.29, and 83.38±14.83 in the BAS+ group and 94.58±18.40, 99.83±15.71, and 90.00±18.73 in the BAS- group, respectively (p=0.131, p=0.123, and p=0.689, respectively). Ballon atrial septostomy was the only factor that caused a decrease in all composite scores according to Bayley-III scoring, although not statistically significant. There was a significant negative correlation between C-reactive protein and all composite scores. There was also a significant negative correlation between cardiopulmonary bypass time, cross-clamping time, mean plasma lactate levels (mmol/L) on postoperative Days 2-5, postoperative creatinine, and motor composite scores. There was a significant positive correlation between growth weight and head circumference and all three CSs.</p><p><strong>Conclusion: </strong>Ballon atrial septostomy may adversely affect the neurodevelopmental process in neonates. We believe that close monitoring of postoperative blood values such as lactate, C-reactive protein and creatinine, and avoiding hypoxemia and keeping them at optimal levels are crucial. Good weight gain can also contribute to the neurodevelopment of patients.</p>","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":"33 2","pages":"185-195"},"PeriodicalIF":0.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The efficacy of topical mitomycin-C in the treatment of benign tracheal stenosis: A comparative study.","authors":"Efsun Gonca Uğur Chousein, Demet Turan, Elif Tanrıverdi, Binnaz Zeynep Yıldırım, Mustafa Vedat Doğru, Halit Çınarka, Mehmet Akif Özgül, Erdoğan Çetinkaya","doi":"10.5606/tgkdc.dergisi.2025.27157","DOIUrl":"10.5606/tgkdc.dergisi.2025.27157","url":null,"abstract":"<p><strong>Background: </strong>This study aims to examine the efficacy of mitomycin-C (MMC) in patients with benign tracheal stenosis who have re-stenosis requiring repeated interventional bronchoscopy.</p><p><strong>Methods: </strong>Between January 2009 and December 2019, a total of 25 patients who underwent repeated procedures for re-stenosis were retrospectively analyzed. The study group consisted of 11 patients (7 males, 4 females; median age: 37 years; range, 16 to 63 years) who underwent MMC following routine dilation and the control group consisted of 14 patients (8 males, 6 females; median age: 52 years; range, 19 to 73 years) who underwent dilation alone and did not receive MMC. Demographic data of the patients, the etiology of stenosis, comorbidities, medications used, imaging studies, location, degree and length of re-stenosis, details of interventional bronchoscopy, pre- and post-procedural time intervals between mechanical dilation, and cost were reviewed.</p><p><strong>Results: </strong>The percentage changes of re-stenosis and mean re-stenotic segment length significantly decreased (p=0.013 and p=0.029, respectively), and the medical cost (p=0.021), and number of repeated dilations (p=0.020) were lower in the MMC-treated group, compared to the control group. However, the improvement rate was not significantly different (p=0.070) between the MMC-treated group and control group.</p><p><strong>Conclusion: </strong>Mitomycin-C is helpful to decrease the tracheal re-stenosis percentage changes and the number of repeated dilations in patients with benign tracheal stenosis. It also decreases the median re-stenotic segment lengths which may be crucial for limited reserve surgery in tracheal resections. Taken together, MMC is a cost-effective, time-saving and tracheal-sparing treatment in patients with benign tracheal stenosis.</p>","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":"33 2","pages":"217-225"},"PeriodicalIF":0.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188966/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcatheter valve-in-valve replacement for degenerated mitral bioprosthesis using Myval device.","authors":"Serkan Aslan, Ahmet Guner, Hande Uysal, Mehmet Ertürk","doi":"10.5606/tgkdc.dergisi.2025.25825","DOIUrl":"10.5606/tgkdc.dergisi.2025.25825","url":null,"abstract":"<p><p>Structural valve deterioration in surgical bioprostheses may require redo valve surgery, which is associated with significant operative mortality and poor long-term survival. As an alternative treatment option, valve-in-valve (ViV) transcatheter mitral valve replacement (TMVR) has emerged for patients with symptomatic and severely degenerated bioprosthetic valves who are at high risk for redo cardiac surgery. This case report describes the first case of transseptal valve-in-valve-transcatheter mitral valve replacement in an 85-year-old female patient in Türkiye. The patient had a degenerated mitral bioprosthesis and was at high surgical risk. The patient had previously undergone valve-in-valve transcatheter aortic valve replacement. The procedure was completed successfully, and there were no complications during the postprocedural course.</p>","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":"33 2","pages":"247-250"},"PeriodicalIF":0.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188961/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thymic IgG4-related disease presenting as a calcified mediastinal mass.","authors":"Iclal Ocak, Furkan Ufuk","doi":"10.5606/tgkdc.dergisi.2025.26894","DOIUrl":"10.5606/tgkdc.dergisi.2025.26894","url":null,"abstract":"","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":"33 2","pages":"260-261"},"PeriodicalIF":0.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188962/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term outcomes of surgery in resectable single-station N2 non-small cell lung cancer patients.","authors":"Bahar Agaoglu Sanli, Serkan Yazgan, Ahmet Ucvet, Esra Yamansavci Şirzai, Yunus Turk","doi":"10.5606/tgkdc.dergisi.2025.27229","DOIUrl":"10.5606/tgkdc.dergisi.2025.27229","url":null,"abstract":"<p><strong>Background: </strong>This study aims to examine the factors influencing prognosis and long-term survival outcomes in pathological single-station N2 (pN2a) patients undergoing surgical treatment for non-small cell lung cancer.</p><p><strong>Methods: </strong>Between January 2012 and June 2021, a total of 144 patients (125 males, 19 females; mean age: 60.5±8.4 years; range, 48 to 78 years) who underwent anatomical resection for non-small cell lung cancer and were identified with pN2a disease were retrospectively analyzed. Factors influencing prognosis were analyzed. Survival analysis was performed.</p><p><strong>Results: </strong>Forty-nine (34%) patients received neoadjuvant therapy and 87 (60.4%) patients underwent lobectomy. In terms of staging, 95 (66%) patients were classified as Stage 3A, while 49 (34%) patients were categorized as Stage 3B. Analysis of N2 subtypes revealed that 77 (53.5%) patients were classified as known N2, whereas 67 (46.5%) patients were identified as incidental. Histopathological evaluation revealed that 58 (40.3%) patients had adenocarcinoma, while 86 (59.7%) patients had non-adenocarcinoma histology. N2 disease was categorized as skip metastasis (pN0N2a) in 61 (42.4%) patients and non-skip metastasis (pN1N2a) in 83 (57.6%) patients. Adjuvant therapy was administered to 126 (87.5%) patients, with treatment modalities determined by the oncology clinics and patient characteristics. Among these, 46 (31.9%) patients received chemotherapy, 15 (10.4%) patients underwent radiotherapy, and 65 (45.1%) patients were treated with chemoradiotherapy. The five-year overall survival rate was 33.9% with a median duration of 37.1±5.0 months. The disease-free survival rate was 24.9% with a median duration of 18.2±2.3 months. Adenocarcinoma histology, non-skip N2 disease, lack of adjuvant therapy, and advanced age (>65 years) were found to be significant factors affecting the prognosis of pN2a disease.</p><p><strong>Conclusion: </strong>The findings of this study indicate that adenocarcinoma histology, advanced age, absence of adjuvant therapy, and the presence of pN1N2a are significant prognostic factors in pN2a patients undergoing curative resection for non-small cell lung cancer.</p>","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":"33 2","pages":"205-216"},"PeriodicalIF":0.5,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188972/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The importance of histology in patient selection for platinum-based neoadjuvant treatment in non-small cell lung cancer.","authors":"Gökhan Kocaman, Yusuf Kahya, Elif Berna Köksoy, Atilla Halil Elhan, Mustafa Bülent Yenigün, Murat Özkan, Cabir Yüksel, Serkan Enön, Ayten Kayı Cangır, Hakan Kutlay, Rıfat Murat Akal","doi":"10.5606/tgkdc.dergisi.2025.27340","DOIUrl":"10.5606/tgkdc.dergisi.2025.27340","url":null,"abstract":"<p><strong>Background: </strong>This study aims to evaluate the prognostic factors for overall survival and progression-free survival in non-small cell lung cancer patients receiving platinum-based neoadjuvant therapy.</p><p><strong>Methods: </strong>Between January 2008 and December 2022, a total of 163 patients with clinical Stages 2B, 3A, and 3B non-small cell lung cancer (148 males, 15 females; mean age: 59.5±7.8 years; range, 33 to 76 years) who underwent operation after neoadjuvant chemotherapy or chemoradiotherapy were retrospectively analyzed. The prognostic factors for overall survival and progression-free survival were evaluated.</p><p><strong>Results: </strong>Higher major pathological response rate (p=0.021) and lower recurrence rate (p=0.009) were observed in patients with squamous cell carcinoma. The five-year progression-free survival rates were 56.9% and 34.1% for patients with squamous and non-squamous cell cancers (p=0.007) and the five-year overall survival rates were 68.2% and 52.2%, respectively (p=0.046). Squamous cell carcinoma histology was a favorable prognostic factor for both progression-free survival (p=0.008) and overall survival OS (p=0.031).</p><p><strong>Conclusion: </strong>Tumor histology may serve as a prognostic factor, helping to predict patient outcomes and guide the selection of neoadjuvant therapies before surgery. Currently, platinum-based chemotherapies are still used as a standard. Clinicians should consider tumor histology while deciding on neoadjuvant treatment.</p>","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":"33 2","pages":"196-204"},"PeriodicalIF":0.5,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188957/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Choosing a thoracic surgeon in Türkiye: Which criteria do patients pay attention to?","authors":"Onur Derdiyok, Uğur Temel, Mehmet Oğuzhan Özyurtkan, Bülent Arslan, Şule Karadayı","doi":"10.5606/tgkdc.dergisi.2025.27110","DOIUrl":"10.5606/tgkdc.dergisi.2025.27110","url":null,"abstract":"<p><strong>Background: </strong>This study aims to identify main factors playing a role in patient's selection of a thoracic surgeon in Türkiye.</p><p><strong>Methods: </strong>Between July 2022 and June 2024, a total of 147 patients (96 males, 41 females; mean age: 56.1±14.7 years; range, 19 to 93 years) who underwent lung resection and completed an anonymous questionnaire sent via e-mail or cell-phone were included. Demographic data of the patients, surgeon's educational and medical background, advertisements and popularity, age and sex, appearance and communication skills, and surgeon's working center were evaluated.</p><p><strong>Results: </strong>\"Spending adequate time with patients\" had the highest score, while \"the distance between surgeon's center and patient's home\" had the lowest score. In general, criteria about surgeon's appearance and communication skills, and surgeon's working center had significantly the highest rates, whereas those of surgeon's advertisements and popularity had the lowest rates (p<0.05). Recommendation by another doctor or family doctor was insignificantly more important than by non-medical person. Patients were not influenced with internet reviews or scoring about the surgeon, presence of surgeon's personal web page, or social media accounts, or age/sex of the surgeon (p>0.05).</p><p><strong>Conclusion: </strong>Turkish patients mostly take into consideration the attitudes of the surgeon rather than surgeon's reputation and professional experience, while selecting a thoracic surgeon. Surgeon-patient interaction is highly important for Turkish patients. Social media and advertisements are not important criteria in the selection of thoracic surgeon in Türkiye.</p>","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":"33 1","pages":"94-101"},"PeriodicalIF":0.5,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931370/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of cardiopulmonary bypass on late-onset hyperlactatemia after pediatric cardiac surgery.","authors":"Behzat Tüzün, Servet Ergün, Şerife Özalp, Mehmet Akif Önalan, Berra Zümrüt Tan Recep, Eymen Recep, İbrahim Cansaran Tanıdır, Erkut Öztürk, Ali Can Hatemi","doi":"10.5606/tgkdc.dergisi.2025.26627","DOIUrl":"10.5606/tgkdc.dergisi.2025.26627","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to investigate the effect of operative and postoperative parameters on late-onset hyperlactatemia (LOHL) after cardiac surgery in the pediatric patient population.</p><p><strong>Methods: </strong>One hundred fifty-nine ventricular septal defect patients (77 males, 82 females; mean age: 8.0±8.6 years; range, 1 to 48 years) were retrospectively examined between August 2020 and February 2023. Patients with the highest lactate value measured between 6 to 12 h postoperatively <3 mmol/L were defined as Group 1, and those with lactate values ≥3 mmol/L (LOHL) were included in Group 2.</p><p><strong>Results: </strong>Cardiopulmonary bypass (CPB) time, aortic cross-clamp time, and CPB flow did not differ between groups (p=0.916, p=0.729, and p=0.699, respectively). The difference between partial oxygen pressure (PaO₂) in the first blood gas obtained after CPB was statistically significant (p=0.017). The lactate level measured in the first arterial blood gas obtained after CPB was 1.74±0.61 mmol/L in Group 1 and 3.01±1.63 mmol/L in Group 2 (p<0.001). The PaO₂ in the arterial blood gas measured at 6 h postoperatively was 129.22±61.20 mmHg in Group 1 and 156.07±64.49 mmHg in Group 2 (p=0.046).</p><p><strong>Conclusion: </strong>The development of hyperlactatemia due to ischemia in the early post-CPB period may affect the development of LOHL. Microcirculatory changes at the tissue level may play a role in the etiology of LOHL.</p>","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":"33 1","pages":"27-35"},"PeriodicalIF":0.5,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931366/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}