Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery最新文献

{"title":"Additional insights into the outcomes after combined heart-lung surgery.","authors":"Rohan Magoon","doi":"10.5606/tgkdc.dergisi.2025.27538","DOIUrl":"10.5606/tgkdc.dergisi.2025.27538","url":null,"abstract":"","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":"33 2","pages":"265-266"},"PeriodicalIF":0.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188955/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial intelligence to predict biomarkers for new-onset atrial fibrillation after coronary artery bypass grafting.","authors":"Birkan Akbulut, Mustafa Çakır, Mustafa Görkem Sarıkaya, Okan Oral, Mesut Yılmaz, Güzin Aykal","doi":"10.5606/tgkdc.dergisi.2025.27304","DOIUrl":"10.5606/tgkdc.dergisi.2025.27304","url":null,"abstract":"<p><strong>Background: </strong>This study aims to identify predictors of postoperative atrial fibrillation in coronary artery bypass grafting patients using routinely collected preoperative tests.</p><p><strong>Methods: </strong>Between January 2020 and December 2023, a total of 50 patients with postoperative atrial fibrillation (POAF group; 39 males, 11 females; mean age: 65.9±8.3 years; range, 38 to 77 years) and 50 without postoperative atrial fibrillation (non-POAF group; 41 males, 9 females; mean age: 61.8±10.0 years; range, 41 to 81 years) were randomly selected from a group of patients undergoing two or three-vessel coronary artery bypass grafting. We analyzed preoperative laboratory, demographic and intraoperative data using machine learning models.</p><p><strong>Results: </strong>The overall incidence of postoperative atrial fibrillation was 21.69%. The three most effective biomarkers were magnesium, total iron binding capacity, and albumin, respectively. A total of 2.0 mg/dL value of magnesium was identified as a threshold value. Magnesium values below 2.0 mg/dL were considered atrial fibrillation-positive, accounting for 25% of the dataset. Total iron binding capacity values higher than 442 µg/dL were considered atrial fibrillation-positive, accounting for 12% of the dataset. The threshold value for albumin was 29 g/dL, and patients with values under this value were considered atrial fibrillation-positive, accounting for 4% of the dataset.</p><p><strong>Conclusion: </strong>Machine learning models demonstrate encouraging results in identifying risk factors for many entities. It is of utmost importance to establish a ranking among risk factors and determine threshold values to support clinicians in decision making. This is our first experience with machine learning in this patient group after cardiac surgery. Further studies are warranted to confirm these data.</p>","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":"33 2","pages":"144-153"},"PeriodicalIF":0.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188970/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of life in patients undergoing lung resection: Evaluation of outcomes of follow-up using brief pain inventory.","authors":"Seda Kahraman Aydın, Ufuk Çağırıcı, Sercan Aydın, Ayşe Gül Ergönül, Tevfik İlker Akçam, Kutsal Turhan, Ali Özdil, Alpaslan Çakan, Ömer Faruk Dadaş","doi":"10.5606/tgkdc.dergisi.2025.27233","DOIUrl":"10.5606/tgkdc.dergisi.2025.27233","url":null,"abstract":"<p><strong>Background: </strong>The aim of the study was to evaluate preoperative anxiety, postoperative pain and functional impairment using Brief Pain Inventory (BPI) in patients undergoing surgery for malignancy.</p><p><strong>Methods: </strong>Between September 2020 and May 2022, a total of 94 patients (60 males, 34 females; mean age 59.5±12.2 years; range, 32 to 84 years) who underwent surgery for lung cancer were prospectively analyzed. The patients were evaluated using the BPI preoperatively and on postoperative Days 0, 3, and 30. The preoperative emotional impacts of patient variables and the influence of surgical management on postoperative pain were examined.</p><p><strong>Results: </strong>Females experienced more preoperative emotional distress and insomnia (p=0.046, p=0.033, respectively). Patients diagnosed with cancer and had a history of surgery or thoracotomy demonstrated higher preoperative emotional distress (p=0.001, p<0.001, p<0.001, respectively). Postoperatively, patients who underwent thoracotomy reported greater pain with higher functional impairment compared to the video-assisted thoracoscopic surgery group (p=0.002, p=0.018, respectively). Patients whose drains were completely removed by the postoperative Day 3 had reduced discomfort and improved ability to perform breathing exercise (p=0.005, p=0.045, respectively). Thoracotomy and the placement of double drains were identified as independent factors contributing to difficulties in performing breathing exercises and coughing on Day 30 (p<0.05 for all). There was no significant difference in the pain scores and affected functions between the patients with a thoracotomy incision size of <10 cm and ≥10 cm (p=0.200, p=0.113, respectively).</p><p><strong>Conclusion: </strong>Our study results indicate that a preference for minimal invasive procedures, the use of a single thoracic drain, and the prompt removal of the drain minimize pain and functional impairment. Women, patients with a preoperative diagnosis of malignancy requiring metastasectomy, and history of thoracotomy or surgery experience elevated levels of anxiety. Therefore, consistent monitoring and psychological support may be recommended to improve the quality of life for this patient population.</p>","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":"33 2","pages":"238-246"},"PeriodicalIF":0.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188964/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Truncus bicaroticus and aberrant right subclavian artery: A rare case mimicking aortic dissection.","authors":"Gokhan Arslan, Ugur Bozlar","doi":"10.5606/tgkdc.dergisi.2025.26213","DOIUrl":"10.5606/tgkdc.dergisi.2025.26213","url":null,"abstract":"","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":"33 2","pages":"257-259"},"PeriodicalIF":0.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188956/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to Letter to the Editor: Additional insights into the outcomes after combined heart-lung surgery.","authors":"Mehmet Şanser Ateş, Zümrüt Tuba Demirözü, Suat Erus, Eray Aksoy, Kadir Burak Özer, Sami Gürkahraman, Ekin Ezgi Cesur, Serhan Tanju","doi":"10.5606/tgkdc.dergisi.2025.50267","DOIUrl":"10.5606/tgkdc.dergisi.2025.50267","url":null,"abstract":"","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":"33 2","pages":"267-268"},"PeriodicalIF":0.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188969/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The prognostic value of the TAPSE/PASP ratio in lung transplant candidates.","authors":"Kadir Bıyıklı, Berhan Keskin, Ali Karagöz, Pınar Atagün Güney, Erdal Taşçı, Mustafa Vayvada, Neşri Danışman, Gökhan Alıcı","doi":"10.5606/tgkdc.dergisi.2025.26847","DOIUrl":"10.5606/tgkdc.dergisi.2025.26847","url":null,"abstract":"<p><strong>Background: </strong>In this study, we aimed to investigate the prognostic value of the tricuspid annular systolic excursion/pulmonary arterial systolic pressure (TAPSE/PASP) ratio as a marker of right ventricle-pulmonary artery uncoupling in patients listed for lung transplantation.</p><p><strong>Methods: </strong>Between January 2011 and December 2020, a total of 173 patients (114 males, 59 females; mean age: 53.1±12.5 years; range, 18 to 77 years) who had advanced lung disease or pulmonary vascular disease and were included in the lung transplant list were retrospectively analyzed. Demographic characteristics, laboratory values, long-term mortality data, and clinical and cardiac catheterization data of the patients were compared using a TAPSE/PASP cut-off value of 0.55 mm/mmHg. The univariate and multivariate regression analyses were performed to identify the value of TAPSE/PASP ratio in predicting long-term mortality. The maximal selective rank test was carried out to determine the optimal cut-off value for TAPSE/PASP ratio.</p><p><strong>Results: </strong>The univariate regression analysis revealed that the TAPSE/PASP ratio, six-minute walk distance, and albumin level were found to be predictors of mortality (hazard ratio [HR]=0.61, 95% confidence interval [CI]: 0.46-0.80, p=0.007; HR=0.72, 95% CI: 0.56-0.91, p=0.007; and HR=0.77, 95% CI: 0.59-0.99, p=0.04, respectively). In the multivariate regression analysis, the TAPSE/PASP ratio, body mass index, and six-minute walk distance were the predictors of mortality (HR=0.49, 95% CI: 0.34-0.70, p=0.004; HR=0.71, 95% CI: 0.51-0.97, p=0.03; and HR=0.71, 95% CI: 0.54-0.94, p=0.01, respectively).Through the maximal selective rank test, the optimal threshold value for TAPSE/PASP ratio was found to be 0.29 mm/mmHg. Patients with TAPSE/PASP >0.29 mm/ mmHg had an average life expectancy of 47.8 months, while the patients with TAPSE/PASP <0.29 mm/mmHg had an average life expectancy of 17.2 months.</p><p><strong>Conclusion: </strong>Our study results suggest that a TAPSE/PASP ratio of <0.29 mm/mmHg is a poor prognostic factor for long-term mortality in patients on the waiting list for lung transplantation.</p>","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":"33 2","pages":"165-175"},"PeriodicalIF":0.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188960/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The potential risks of artificial intelligence in cardiovascular care.","authors":"Hakan Göçer, Ahmet Barış Durukan","doi":"10.5606/tgkdc.dergisi.2025.26912","DOIUrl":"10.5606/tgkdc.dergisi.2025.26912","url":null,"abstract":"","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":"33 2","pages":"262-264"},"PeriodicalIF":0.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188959/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors determining early mortality in ischemic mitral regurgitation surgery.","authors":"Batuhan Yazıcı, Zinar Apaydın, Mustafa Can Kaplan, Alkım Ateşli Yazıcı, Barış Timur, Kübra Gözaçık, Elif Güneysu, Soner Sanioğlu","doi":"10.5606/tgkdc.dergisi.2025.27206","DOIUrl":"10.5606/tgkdc.dergisi.2025.27206","url":null,"abstract":"<p><strong>Background: </strong>This study aims to identify the causes of early mortality in patients undergoing mitral valve surgery performed in combination with coronary artery bypass grafting for the treatment of ischemic mitral regurgitation.</p><p><strong>Methods: </strong>Between January 2017 and January 2023, a total of 411 patients (272 males, 139 females; mean age: 63.1±9.1 years; range, 32 to 92 years) who underwent coronary artery bypass grafting and mitral valve surgery due to ischemic mitral regurgitation were retrospectively analyzed. The primary outcome measure of the study was in-hospital mortality. The patients were divided into two groups as those with and without in-hospital mortality. Variables affecting mortality were identified.</p><p><strong>Results: </strong>In-hospital mortality was observed in 13.6% (n=56) of the patients. Elective surgery was performed in 308 patients (74.9%), while priority surgery was performed in 103 patients (25.1%). Mortality rate was 9.1% in elective cases and 27.1% in priority cases. Independent risk factors for mortality included age (p=0.001), female sex (p<0.001), priority surgery (p=0.005), low left ventricular ejection fraction (p=0.005), high creatinine levels (p=0.002), the presence of extracardiac arteriopathy (p=0.042), and prolonged cardiopulmonary bypass time (p<0.001). In priority cases, a waiting period of ≤9 days was associated with higher mortality (area under the curve: 0.781, sensitivity: 75%, specificity: 72%, p<0.001).</p><p><strong>Conclusion: </strong>A comprehensive preoperative evaluation is crucial for optimizing outcomes in patients with ischemic mitral regurgitation. In high-risk cases, the use of less invasive approaches, such as percutaneous interventions, can be considered potential alternatives. In priority cases, if hemodynamic stability can be achieved, waiting nine days after the index event before performing surgical intervention may significantly reduce perioperative and in-hospital mortality rates.</p>","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":"33 2","pages":"154-164"},"PeriodicalIF":0.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of preoperative balloon atrial septostomy and intraoperative parameters on neurodevelopmental scoring in neonates operated for transposition of the great artery.","authors":"Yiğit Kılıç, Şenay Güven Baysal, Özlem Gül, Bedri Aldudak","doi":"10.5606/tgkdc.dergisi.2025.26431","DOIUrl":"10.5606/tgkdc.dergisi.2025.26431","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to investigate the effect of preoperative balloon atrial septostomy and intraoperative parameters on neurodevelopmental outcomes in neonates operated for transposition of the great arteries.</p><p><strong>Methods: </strong>Between February 2018 and March 2022, a total of 60 patients (49 male, 11 female; mean age, 23.5±8.8 days; range, 2 to 106 days) who were operated with a diagnosis of simple transposition of the great arteries and discharged uneventfully were included. Preoperative balloon atrial septostomy was performed in 33 patients (BAS+ group), while 27 patients (BAS- group) did not undergo the procedure. Finally, 13 patients from the septostomy group and 12 patients from the non-septostomy group were available for follow-up. Neurodevelopment in infants was assessed using the 3^rd edition of the Bayley Scales of Infant and Toddler Development (Bayley-III) scoring.</p><p><strong>Results: </strong>The mean cognitive, language, and motor composite scores were 85.00±11.73, 89.62±12.29, and 83.38±14.83 in the BAS+ group and 94.58±18.40, 99.83±15.71, and 90.00±18.73 in the BAS- group, respectively (p=0.131, p=0.123, and p=0.689, respectively). Ballon atrial septostomy was the only factor that caused a decrease in all composite scores according to Bayley-III scoring, although not statistically significant. There was a significant negative correlation between C-reactive protein and all composite scores. There was also a significant negative correlation between cardiopulmonary bypass time, cross-clamping time, mean plasma lactate levels (mmol/L) on postoperative Days 2-5, postoperative creatinine, and motor composite scores. There was a significant positive correlation between growth weight and head circumference and all three CSs.</p><p><strong>Conclusion: </strong>Ballon atrial septostomy may adversely affect the neurodevelopmental process in neonates. We believe that close monitoring of postoperative blood values such as lactate, C-reactive protein and creatinine, and avoiding hypoxemia and keeping them at optimal levels are crucial. Good weight gain can also contribute to the neurodevelopment of patients.</p>","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":"33 2","pages":"185-195"},"PeriodicalIF":0.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The importance of histology in patient selection for platinum-based neoadjuvant treatment in non-small cell lung cancer.","authors":"Gökhan Kocaman, Yusuf Kahya, Elif Berna Köksoy, Atilla Halil Elhan, Mustafa Bülent Yenigün, Murat Özkan, Cabir Yüksel, Serkan Enön, Ayten Kayı Cangır, Hakan Kutlay, Rıfat Murat Akal","doi":"10.5606/tgkdc.dergisi.2025.27340","DOIUrl":"10.5606/tgkdc.dergisi.2025.27340","url":null,"abstract":"<p><strong>Background: </strong>This study aims to evaluate the prognostic factors for overall survival and progression-free survival in non-small cell lung cancer patients receiving platinum-based neoadjuvant therapy.</p><p><strong>Methods: </strong>Between January 2008 and December 2022, a total of 163 patients with clinical Stages 2B, 3A, and 3B non-small cell lung cancer (148 males, 15 females; mean age: 59.5±7.8 years; range, 33 to 76 years) who underwent operation after neoadjuvant chemotherapy or chemoradiotherapy were retrospectively analyzed. The prognostic factors for overall survival and progression-free survival were evaluated.</p><p><strong>Results: </strong>Higher major pathological response rate (p=0.021) and lower recurrence rate (p=0.009) were observed in patients with squamous cell carcinoma. The five-year progression-free survival rates were 56.9% and 34.1% for patients with squamous and non-squamous cell cancers (p=0.007) and the five-year overall survival rates were 68.2% and 52.2%, respectively (p=0.046). Squamous cell carcinoma histology was a favorable prognostic factor for both progression-free survival (p=0.008) and overall survival OS (p=0.031).</p><p><strong>Conclusion: </strong>Tumor histology may serve as a prognostic factor, helping to predict patient outcomes and guide the selection of neoadjuvant therapies before surgery. Currently, platinum-based chemotherapies are still used as a standard. Clinicians should consider tumor histology while deciding on neoadjuvant treatment.</p>","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":"33 2","pages":"196-204"},"PeriodicalIF":0.5,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188957/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}