{"title":"Ultrasonographic Findings and Prognosis of Metastases to the Thyroid Gland.","authors":"Wenting Xie, Yaoqin Wang, Zhongshi Du, Yijie Chen, Yu Wu, Dongdong Zhu, Lina Tang","doi":"10.1177/01617346231179620","DOIUrl":"10.1177/01617346231179620","url":null,"abstract":"<p><p>Metastases to the thyroid gland (MTT) are uncommon in clinical practice. The ultrasound (US) features are easily confused with primary thyroid malignancy, Hashimoto's thyroiditis, and other thyroid diseases. Therefore, this study aimed to assess the role of US and analysis of prognosis of MTT. A total of 45 patients with MTT in the database between July 2009 and February 2022 at the Fujian Cancer Hospital were reviewed. US examinations were performed only on 20 patients, who were finally included in our study. Among the 20 patients, nine were male, and eleven were female. According to US characteristics, metastases to the thyroid gland were divided into nodular and diffuse types (17 and 3 cases, respectively). Three lesions (17.6%) had circumscribed margins, and 14 (82.4%) were uncircumscribed. Three lesions (17.6%) were regular in shape, and 14 (82.4%) were irregular. Nine metastases (52.9%) were a taller-than-wide shape, and eight (47.1%) were not a taller-than-wide shape. Ten lesions (58.8%) had rich vascularity, and seven (41.2%) had absence/not rich vascularity. The mean overall survival (OS) from the time of MTT diagnosis was 22 months (95% confidence interval: 5.95-38.05). The 1-, 3-, and 5-year OS after metastasis was 68.1%, 25.5%, and 17%, respectively. The prognosis of MTT was poor, which is closely related to the characteristics of the primary tumor and metastatic disease. The US findings and US-guided core needle biopsy may be useful in diagnosing MTT in patients with a history of the malignant tumors.</p>","PeriodicalId":49401,"journal":{"name":"Ultrasonic Imaging","volume":" ","pages":"219-226"},"PeriodicalIF":2.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9756478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Louise Zhuang, Walter Simson, Oleksii Ostras, Jeremy Dahl, cristian rios, Jahani Jirsaraei, Erica L. King, A. Bashatah, Brian M. Guthrie, Margaret T. Jones, Qi Wei, S. Sikdar, V. chitnis, David Alberico, D. DiCenzo, Joyce yip, L. Sannachi, frances Wright, M. Oelze, O. Falou, sannachi, J. czarnota, M. Kolios, Kazuyo Ito, Quan V Hoang, A. mcfadden, Jonathan Mamou
{"title":"UITC Abstracts 2023","authors":"Louise Zhuang, Walter Simson, Oleksii Ostras, Jeremy Dahl, cristian rios, Jahani Jirsaraei, Erica L. King, A. Bashatah, Brian M. Guthrie, Margaret T. Jones, Qi Wei, S. Sikdar, V. chitnis, David Alberico, D. DiCenzo, Joyce yip, L. Sannachi, frances Wright, M. Oelze, O. Falou, sannachi, J. czarnota, M. Kolios, Kazuyo Ito, Quan V Hoang, A. mcfadden, Jonathan Mamou","doi":"10.1177/01617346231186897","DOIUrl":"https://doi.org/10.1177/01617346231186897","url":null,"abstract":"Background: Speed-of-sound (SoS) in the liver has been postulated as a quantitative biomarker for stratification of non-alcoholic faty liver disease (NAFLD). SoS in adipose tissue is lower than in healthy liver. Recently, we have proposed a pulse-echo SoS reconstruction method based on full synthetic aperture (FSA) data. While existing methods apply a delay-and-sum or similar beamforming operation, in our method we apply delays and a spatio-temporal filter and then correlate channels directly without summing, thus avoiding spatial biases when the sound speed is mismatched. Here we analyze the feasibility of this method to reconstruct SoS in murine liver. Methods: We","PeriodicalId":49401,"journal":{"name":"Ultrasonic Imaging","volume":"36 1","pages":"241 - 283"},"PeriodicalIF":2.3,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79384414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ultrasonic ImagingPub Date : 2023-07-01Epub Date: 2023-04-27DOI: 10.1177/01617346231171147
Andrew P Santoso, Ivan Rosado-Mendez, Quinton W Guerrero, Timothy J Hall
{"title":"A Geometric Model of Ultrasound Backscatter to Describe Microstructural Anisotropy of Tissue.","authors":"Andrew P Santoso, Ivan Rosado-Mendez, Quinton W Guerrero, Timothy J Hall","doi":"10.1177/01617346231171147","DOIUrl":"10.1177/01617346231171147","url":null,"abstract":"<p><p>Methods to assess ultrasound backscatter anisotropy from clinical array transducers have recently been developed. However, they do not provide information about the anisotropy of microstructural features of the specimens. This work develops a simple geometric model, referred to as the <i>secant model</i>, of backscatter coefficient anisotropy. Specifically, we evaluate anisotropy of the frequency dependence of the backscatter coefficient parameterized in terms of effective scatterer size. We assess the model in phantoms with known scattering sources and in a skeletal muscle, a well-known anisotropic tissue. We demonstrate that the secant model can determine the orientation of the anisotropic scatterers, as well as accurately determining effective scatterer sizes, and it may classify isotropic versus anisotropic scatterers. The secant model may find utility in monitoring disease progression as well as characterizing normal tissue architectures.</p>","PeriodicalId":49401,"journal":{"name":"Ultrasonic Imaging","volume":"45 4","pages":"206-214"},"PeriodicalIF":2.5,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11296378/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9754719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anne-Lise Duroy, Valérie Detti, Agnès Coulon, Olivier Basset, Elisabeth Brusseau
{"title":"Regularization-Based 2D Strain Tensor Imaging in Quasi-Static Ultrasound Elastography <i>SAGE Publications</i>.","authors":"Anne-Lise Duroy, Valérie Detti, Agnès Coulon, Olivier Basset, Elisabeth Brusseau","doi":"10.1177/01617346231168982","DOIUrl":"https://doi.org/10.1177/01617346231168982","url":null,"abstract":"<p><p>Accurately estimating all strain components in quasi-static ultrasound elastography is crucial for the full analysis of biological media. In this study, 2D strain tensor imaging was investigated, focusing on the use of a regularization method to improve strain images. This method enforces the tissue property of (quasi-) incompressibility, while penalizing strong field variations, to smooth the displacement fields and reduce the noise in the strain components. The performance of the method was assessed with numerical simulations, phantoms, and in vivo breast tissues. For all the media examined, the results showed a significant improvement in both lateral displacement and strain, while axial fields were only slightly modified by the regularization. The introduction of penalty terms allowed us to obtain shear strain and rotation elastograms where the patterns around the inclusions/lesions were clearly visible. In phantom cases, the findings were consistent with the results obtained from the modeling of the experiments. Finally, the easier detectability of the inclusions/lesions in the final lateral strain images was associated with higher elastographic contrast-to-noise ratios (CNRs), with values in the range of [0.54-9.57] versus [0.08-0.38] before regularization.</p>","PeriodicalId":49401,"journal":{"name":"Ultrasonic Imaging","volume":"45 4","pages":"187-205"},"PeriodicalIF":2.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10044382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rui Wang, Haoyuan Zhou, Peng Fu, Hui Shen, Yang Bai
{"title":"A Multiscale Attentional Unet Model for Automatic Segmentation in Medical Ultrasound Images.","authors":"Rui Wang, Haoyuan Zhou, Peng Fu, Hui Shen, Yang Bai","doi":"10.1177/01617346231169789","DOIUrl":"https://doi.org/10.1177/01617346231169789","url":null,"abstract":"<p><p>Ultrasonography has become an essential part of clinical diagnosis owing to its noninvasive, and real-time nature. To assist diagnosis, automatically segmenting a region of interest (ROI) in ultrasound images is becoming a vital part of computer-aided diagnosis (CAD). However, segmenting ROIs on medical images with relatively low contrast is a challenging task. To better achieve medical ROI segmentation, we propose an efficient module denoted as multiscale attentional convolution (MSAC), utilizing cascaded convolutions and a self-attention approach to concatenate features from various receptive field scales. Then, MSAC-Unet is constructed based on Unet, employing MSAC instead of the standard convolution in each encoder and decoder for segmentation. In this study, two representative types of ultrasound images, one of the thyroid nodules and the other of the brachial plexus nerves, were used to assess the effectiveness of the proposed approach. The best segmentation results from MSAC-Unet were achieved on two thyroid nodule datasets (TND-PUH3 and DDTI) and a brachial plexus nerve dataset (NSD) with Dice coefficients of 0.822, 0.792, and 0.746, respectively. The analysis of segmentation results shows that our MSAC-Unet greatly improves the segmentation accuracy with more reliable ROI edges and boundaries, decreasing the number of erroneously segmented ROIs in ultrasound images.</p>","PeriodicalId":49401,"journal":{"name":"Ultrasonic Imaging","volume":"45 4","pages":"159-174"},"PeriodicalIF":2.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10043862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ultrasonic ImagingPub Date : 2023-07-01Epub Date: 2023-05-02DOI: 10.1177/01617346231171895
Derek Y Chan, Daniel Cody Morris, Thomas J Polascik, Mark L Palmeri, Kathryn R Nightingale
{"title":"Combined ARFI and Shear Wave Imaging of Prostate Cancer: Optimizing Beam Sequences and Parameter Reconstruction Approaches.","authors":"Derek Y Chan, Daniel Cody Morris, Thomas J Polascik, Mark L Palmeri, Kathryn R Nightingale","doi":"10.1177/01617346231171895","DOIUrl":"10.1177/01617346231171895","url":null,"abstract":"<p><p>This study demonstrates the implementation of a shear wave reconstruction algorithm that enables concurrent acoustic radiation force impulse (ARFI) imaging and shear wave elasticity imaging (SWEI) of prostate cancer and zonal anatomy. The combined ARFI/SWEI sequence uses closely spaced push beams across the lateral field of view and simultaneously tracks both on-axis (within the region of excitation) and off-axis (laterally offset from the excitation) after each push beam. Using a large number of push beams across the lateral field of view enables the collection of higher signal-to-noise ratio (SNR) shear wave data to reconstruct the SWEI volume than is typically acquired. The shear wave arrival times were determined with cross-correlation of shear wave velocity signals in two dimensions after 3-D directional filtering to remove reflection artifacts. To combine data from serially interrogated lateral push locations, arrival times from different pushes were aligned by estimating the shear wave propagation time between push locations. Shear wave data acquired in an elasticity lesion phantom and reconstructed using this algorithm demonstrate benefits to contrast-to-noise ratio (CNR) with increased push beam density and 3-D directional filtering. Increasing the push beam spacing from 0.3 to 11.6 mm (typical for commercial SWEI systems) resulted in a 53% decrease in CNR. In human <i>in vivo</i> data, this imaging approach enabled high CNR (1.61-1.86) imaging of histologically-confirmed prostate cancer. The <i>in vivo</i> images had improved spatial resolution and CNR and fewer reflection artifacts as a result of the high push beam density, the high shear wave SNR, the use of multidimensional directional filtering, and the combination of shear wave data from different push beams.</p>","PeriodicalId":49401,"journal":{"name":"Ultrasonic Imaging","volume":"45 4","pages":"175-186"},"PeriodicalIF":2.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9687781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ultrasound Homodyned-K Contrast-Weighted Summation Parametric Imaging Based on H-scan for Detecting Microwave Ablation Zones.","authors":"Sinan Li, Zhuhuang Zhou, Shuicai Wu, Weiwei Wu","doi":"10.1177/01617346231162928","DOIUrl":"https://doi.org/10.1177/01617346231162928","url":null,"abstract":"<p><p>The homodyned-K (HK) distribution is a generalized model of envelope statistics whose parameters <i>α</i> (the clustering parameter) and <i>k</i> (the coherent-to-diffuse signal ratio) can be used to monitor the thermal lesions. In this study, we proposed an ultrasound HK contrast-weighted summation (CWS) parametric imaging algorithm based on the H-scan technique and investigated the optimal window side length (WSL) of the HK parameters estimated by the XU estimator (an estimation method based on the first moment of the intensity and two log-moments, which was used in the proposed algorithm) through phantom simulations. H-scan diversified ultrasonic backscattered signals into low- and high-frequency passbands. After envelope detection and HK parameter estimation for each frequency band, the <i>α</i> and <i>k</i> parametric maps were obtained, respectively. According to the contrast between the target region and background, the (<i>α</i> or <i>k</i>) parametric maps of the dual-frequency band were weighted and summed, and then the CWS images were yielded by pseudo-color imaging. The proposed HK CWS parametric imaging algorithm was used to detect the microwave ablation coagulation zones of porcine liver ex vivo under different powers and treatment durations. The performance of the proposed algorithm was compared with that of the conventional HK parametric imaging and frequency diversity and compounding Nakagami imaging algorithms. For two-dimensional HK parametric imaging, it was found that a WSL equal to 4 pulse lengths of the transducer was sufficient for estimating the <i><i>α</i></i> and <i>k</i> parameters in terms of both parameter estimation stability and parametric imaging resolution. The HK CWS parametric imaging provided an improved contrast-to-noise ratio over conventional HK parametric imaging, and the HK <i>α</i><sub>cws</sub> parametric imaging achieved the best accuracy and Dice score of coagulation zone detection.</p>","PeriodicalId":49401,"journal":{"name":"Ultrasonic Imaging","volume":"45 3","pages":"119-135"},"PeriodicalIF":2.3,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10043396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mirela Liana Gliga, Cristian Chirila, Paula Maria Chirila
{"title":"Ultrasound Patterns and Disease Progression in Medullary Sponge Kidney in Adults.","authors":"Mirela Liana Gliga, Cristian Chirila, Paula Maria Chirila","doi":"10.1177/01617346231165493","DOIUrl":"https://doi.org/10.1177/01617346231165493","url":null,"abstract":"<p><p>Our paper presents the ultrasound (US) patterns of a rare kidney disease-medullary sponge kidney (MSK)-that have not been described before in comparison with other causes of medullary hyperechogenicity and correlates them with the severity of the disease and prognosis. This is a clinical observational study of all US examinations in the Nephrology Department over a period of 6 years. The abdominal US focused on the kidneys was recorded. US characteristics of the medulla and cortex were analyzed. We found 10 patients with characteristic daisy flower (DF) kidneys. Positive diagnosis in association with other renal risk factors, prognosis, and evolution were evaluated. Two patterns of medullary hyperechogenicity were found and were correlated with disease severity and kidney function. The first pattern is a homogenous echogenicity of the medulla described as a \"daisy-like\" appearance. The second pattern: calcifications associated with medullar echogenicity, stone production, nephrocalcinosis, and impaired kidney function: \"atypical daisy-like.\" Medullary hyperechogenicity can have more US patterns. In MSK, if the medullary echogenicity is homogenous the evolution is benign, whereas the second, inhomogeneous pattern, has a variable clinical presentation with nephrocalcinosis and the outcome is more severe, leading to chronic kidney disease and impairing the quality of life.</p>","PeriodicalId":49401,"journal":{"name":"Ultrasonic Imaging","volume":"45 3","pages":"151-155"},"PeriodicalIF":2.3,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9678639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Synthetic Aperture Ultrasound Imaging through Adaptive Integrated Transmitting-Receiving Beamformer.","authors":"Hasti Rostamikhanghahi, Sayed Mahmoud Sakhaei","doi":"10.1177/01617346231163835","DOIUrl":"https://doi.org/10.1177/01617346231163835","url":null,"abstract":"<p><p>Synthetic aperture (SA) technique is very attractive for ultrafast ultrasound imaging, as the entire medium can be insonified by a single emission. It also permits applying the dynamic focusing as well as adaptive beamforming both in transmission and reception, which results in an enhanced image. In this paper, we firstly show that the problem of designing the transmit and receive beamformers in SA structure can be formulated as a problem of designing a one-way beamformer on a virtual array with a lateral response equal to that of the two-way beamformer on SA. It is also demonstrated that the length of the virtual aperture is increased to the sum of the transmit aperture length and the receive one, which can result in an enhanced resolution. Moreover, a better estimation of the covariance matrix can be obtained which can be utilized for applying adaptive minimum variance (MV) beamforming method on the virtual array, and consequently the resolution and contrast properties would be enhanced. The performance of the new method is compared with other existing MV-based methods and is quantified by some metrics such as the full width at half maximum (FWHM) and generalized contrast to noise ratio (GCNR). Our validations on simulations and experimental data have shown that the new method is capable of obtaining higher GCNR values while retaining or decreasing FWHM values almost all the time. Moreover, for the same subarray length for estimating the covariance matrices, the computational burden of the new method is significantly lower than those of the existing rival methods.</p>","PeriodicalId":49401,"journal":{"name":"Ultrasonic Imaging","volume":"45 3","pages":"101-118"},"PeriodicalIF":2.3,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9690787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}