A Geometric Model of Ultrasound Backscatter to Describe Microstructural Anisotropy of Tissue.

IF 2.5 4区 医学 Q1 ACOUSTICS
Ultrasonic Imaging Pub Date : 2023-07-01 Epub Date: 2023-04-27 DOI:10.1177/01617346231171147
Andrew P Santoso, Ivan Rosado-Mendez, Quinton W Guerrero, Timothy J Hall
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引用次数: 0

Abstract

Methods to assess ultrasound backscatter anisotropy from clinical array transducers have recently been developed. However, they do not provide information about the anisotropy of microstructural features of the specimens. This work develops a simple geometric model, referred to as the secant model, of backscatter coefficient anisotropy. Specifically, we evaluate anisotropy of the frequency dependence of the backscatter coefficient parameterized in terms of effective scatterer size. We assess the model in phantoms with known scattering sources and in a skeletal muscle, a well-known anisotropic tissue. We demonstrate that the secant model can determine the orientation of the anisotropic scatterers, as well as accurately determining effective scatterer sizes, and it may classify isotropic versus anisotropic scatterers. The secant model may find utility in monitoring disease progression as well as characterizing normal tissue architectures.

描述组织微观结构各向异性的超声波反向散射几何模型
最近开发出了评估临床阵列传感器超声反向散射各向异性的方法。然而,这些方法无法提供标本微观结构特征的各向异性信息。这项研究开发了一种简单的后向散射系数各向异性几何模型,称为正割模型。具体来说,我们评估了以有效散射体尺寸为参数的后向散射系数随频率变化的各向异性。我们在具有已知散射源的模型和骨骼肌(一种众所周知的各向异性组织)中对该模型进行了评估。我们证明,正割模型可以确定各向异性散射体的方向,并准确确定有效散射体的大小,还可以对各向同性散射体和各向异性散射体进行分类。该正割模型可用于监测疾病进展和描述正常组织结构。
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来源期刊
Ultrasonic Imaging
Ultrasonic Imaging 医学-工程:生物医学
CiteScore
5.10
自引率
8.70%
发文量
15
审稿时长
>12 weeks
期刊介绍: Ultrasonic Imaging provides rapid publication for original and exceptional papers concerned with the development and application of ultrasonic-imaging technology. Ultrasonic Imaging publishes articles in the following areas: theoretical and experimental aspects of advanced methods and instrumentation for imaging
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