Undersea and Hyperbaric Medicine最新文献

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A Critical Look at Soft-Sided and Hard-Sided "Mild" Hyperbaric Chambers - Risks, Regulations, and Ethical Oversights. 对软面和硬面“温和”高压舱的批判性审视——风险、法规和道德疏忽。
IF 0.6 4区 医学
Undersea and Hyperbaric Medicine Pub Date : 2026-03-01
Ryan A Murray
{"title":"A Critical Look at Soft-Sided and Hard-Sided \"Mild\" Hyperbaric Chambers - Risks, Regulations, and Ethical Oversights.","authors":"Ryan A Murray","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Soft-sided hyperbaric chambers, as well as some hard-sided (mild) hyperbaric chambers, which are low-pressure, hyperbaric chambers that are typically designed for operational pressures of 3-5psi, have gained popularity in recent years. They are marketed as safe and effective for various conditions but lack compliance with critical regulatory and safety standards and codes. This raises concerns regarding patient safety, the validity of manufacturers' claims, and the ethical obligations of medical professionals and regulators.</p><p><p>This manuscript examines the risks, regulatory gaps, and ethical implications of using soft-sided fabric chambers, as well as hard-sided (mild) hyperbaric chambers, focusing on their failure to meet FDA clearance, NFPA 99 & NFPA 101 codes, and ASME-PVHO standards.</p><p><p>A comprehensive review of regulatory guidelines, safety reports, and marketing practices was conducted, supplemented by illustrations of adverse events linked to the use of these devices. Ethical principles, including beneficence, non-maleficence, and informed consent, were applied to analyze the responsibilities of manufacturers, healthcare providers, patients, and regulators.</p><p><p>These chambers are often marketed with misleading claims about their efficacy and safety. Their non-compliance with FDA clearance, as well as not following industry standards and safety codes increases the risk of patient harm, including otic and pulmonary barotrauma, suffocation, fire hazards, structural failure, and, in extreme cases, death. Regulatory oversight remains inconsistent, allowing manufacturers to exploit loopholes. Furthermore, ethical concerns arise when patients are not fully informed of the limitations and risks of these devices.</p><p><p>The widespread use of these hyperbaric chambers poses significant safety and ethical challenges. Stricter enforcement of regulatory standards and codes, transparent marketing practices, and ethical accountability from healthcare providers and manufacturers are essential to protect patients and uphold public trust in medical technologies.</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"53 3","pages":"523-534"},"PeriodicalIF":0.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149117301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
UHMS Position Statement: Standardization of Terminology in Undersea and Hyperbaric Medicine: Adoption of "Hyperbaric Oxygen Treatment". UHMS立场声明:海底和高压氧医学术语标准化:采用“高压氧治疗”。
IF 0.6 4区 医学
Undersea and Hyperbaric Medicine Pub Date : 2026-03-01
O J O'Neill, M Kelly, D Shapshak
{"title":"UHMS Position Statement: Standardization of Terminology in Undersea and Hyperbaric Medicine: Adoption of \"Hyperbaric Oxygen Treatment\".","authors":"O J O'Neill, M Kelly, D Shapshak","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Hyperbaric medicine terminology has historically lacked standardization, with multiple terms and abbreviations used interchangeably across clinical practice, scientific publications, educational materials, and public communications.</p><p><p>Inconsistent nomenclature may contribute to confusion regarding the definition, regulation, clinical standards, and physician oversight associated with hyperbaric oxygen treatment.</p><p><p>The Undersea and Hyperbaric Medical Society (UHMS) endorses the term hyperbaric oxygen treatment as the preferred terminology for clinically delivered hyperbaric oxygen under accepted UHMS standards.</p><p><p>The Society recommends adoption of the abbreviation HBO₂ or HBO₂ treatment in place of HBOT across manuscripts, presentations, educational content, and operational documents.</p><p><p>Consistent nomenclature is intended to improve clarity and communication among clinicians, researchers, regulatory agencies, payers, referring providers, and the public.</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"53 3","pages":"541-542"},"PeriodicalIF":0.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149117502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the Effect of Hyperbaric Oxygen Preconditioning in Spinal Cord Injury Rats Using Diffusion Tensor Imaging. 应用弥散张量成像评价高压氧预处理对脊髓损伤大鼠的影响。
IF 0.6 4区 医学
Undersea and Hyperbaric Medicine Pub Date : 2026-03-01
Zhongyue Wu, Xinyi Yang, Chenlu Li, Huimin Lai, Ying Liu, Chenhui Zhang, Dairong Cao, Fang Liu
{"title":"Evaluation of the Effect of Hyperbaric Oxygen Preconditioning in Spinal Cord Injury Rats Using Diffusion Tensor Imaging.","authors":"Zhongyue Wu, Xinyi Yang, Chenlu Li, Huimin Lai, Ying Liu, Chenhui Zhang, Dairong Cao, Fang Liu","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>UTo investigate the potential value of diffusion tensor imaging (DTI) in spinal cord injury (SCI) rats undergoing hyperbaric oxygen preconditioning (HBO-PC) at different time points.</p><p><strong>Methods: </strong>Seventy-two rats were randomly allocated into three groups: sham-operated group (laminectomy only); SCI group (the spinal cord weight dropping model); HBO-PC group (HBO-PC for five consecutive days before SCI). Each group was further randomized into four time-point subgroups (6 hours, 24 hours, three days, seven days). Basso, Beattie, Bresnahan (BBB) scores and DTI parameters, including fractional anisotropy (FA), axial diffusivity (AD), radial diffusivity (RD), and mean diffusivity (MD), were collected and analyzed. Spinal cord tissues were processed for hematoxylin, eosin, and Nissl staining.</p><p><strong>Results: </strong>HBO-PC groups exhibited higher FA values than SCI groups at different time points (all p < 0.05). RD and MD values were higher in SCI groups than in HBO-PC groups from 24 hours to 7 days (all p < 0.05). The SCI group showed more pronounced inflammatory cell infiltration and neuronal atrophy than the HBO-PC group. The number of surviving neurons in the injured spinal cord in the HBO-PC group was higher than that in the SCI group at each time point (all p < 0.05). FA values were negatively correlated with BBB scores, while RD and MD values were positively correlated with BBB scores.</p><p><strong>Discussion: </strong>HBO-PC can reduce neuronal cell death and promote nerve function recovery. DTI can quantitatively evaluate HBO-PC's protective effect in rats with SCI.</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"53 3","pages":"455-466"},"PeriodicalIF":0.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149117266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Saturation Diving Decompression Treatment for Severe Type II Decompression Sickness Following Emergency Ascent. 紧急上升后严重II型减压病的饱和潜水减压治疗。
IF 0.6 4区 医学
Undersea and Hyperbaric Medicine Pub Date : 2026-03-01
Du Jishan, Shen Quan, Zhang Hao, Tang Yongmei, Wu Shasha, Wang Weiwei, Liu Yu, Wu Jianguo
{"title":"Saturation Diving Decompression Treatment for Severe Type II Decompression Sickness Following Emergency Ascent.","authors":"Du Jishan, Shen Quan, Zhang Hao, Tang Yongmei, Wu Shasha, Wang Weiwei, Liu Yu, Wu Jianguo","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Decompression sickness (DCS) is a critical concern in diving operations. Severe type II DCS, characterized by neurological involvement, is particularly disabling and life - threatening. Traditional decompression treatments often show limitations in severe cases. This case report highlights the effectiveness of saturation diving decompression in the treatment of such severe DCS.</p><p><strong>Case report: </strong>A 33-year-old male diver experienced severe type II decompression sickness (DCS) following an emergency ascent from a depth of 56 meters of seawater (msw) due to an underwater explosion. The condition was characterized by coma, as well as bleeding from the nose and ears. Initial treatment utilizing a 60 msw recompression protocol demonstrated limited efficacy, with symptom recurrence observed during the decompression process. Subsequently, a 15 msw air saturation diving decompression treatment was implemented, which extended the stay time at each station to facilitate the desaturation of gas bubbles. The patient's symptoms improved significantly. Repeat MRI 4 days later showed a ≥50 % reduction in lesion volume. The patient was discharged neurologically intact on day 11 and, at 3-month follow-up, had resumed land-based duties without sequelae.</p><p><strong>Discussion: </strong>This case underscores the effectiveness of saturation diving decompression in the management of severe DCS, highlighting the critical role of ultra-high-pressure recompression and prolonged desaturation periods.</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"53 3","pages":"417-422"},"PeriodicalIF":0.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149117325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hyperbaric Oxygen as a Treatment Modality for Radiation-Induced Breast Calcinosis. 高压氧作为放射性乳腺钙质沉着症的一种治疗方式。
IF 0.6 4区 医学
Undersea and Hyperbaric Medicine Pub Date : 2026-03-01
Derek B Asserson, Devra B Becker, Tony L Alleman, Dani Kruchevsky
{"title":"Hyperbaric Oxygen as a Treatment Modality for Radiation-Induced Breast Calcinosis.","authors":"Derek B Asserson, Devra B Becker, Tony L Alleman, Dani Kruchevsky","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Breast calcinosis is a rare late complication of radiation therapy that can present years after treatment and pose significant reconstructive challenges. Management of radiation-induced breast calcinosis requires an approach to address both tissue damage and impaired wound healing.</p><p><strong>Case report: </strong>We present a case of a 59-year-old female who developed breast calcinosis more than a decade following radiation. Our multistep treatment plan, which has not been previously published, involved hyperbaric oxygen (HBO₂) treatment, surgical excision, negative pressure wound therapy, and additional HBO₂ treatment. As a result, the patient's wound decreased to 95% of its size in less than two months.</p><p><strong>Discussion: </strong>This case highlights the potential utility of a staged multidisciplinary approach for managing radiation-induced breast calcinosis and supports further investigation of HBO₂ treatment as an adjunct to optimize wound healing in these complex patients.</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"53 3","pages":"467-470"},"PeriodicalIF":0.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149117228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Case Report of Penile Necrosis Successfully Treated With Early Hyperbaric Oxygen Treatment. 早期高压氧治疗成功治疗阴茎坏死1例。
IF 0.6 4区 医学
Undersea and Hyperbaric Medicine Pub Date : 2026-02-01
İbrahim Ethem Akın, Mustafa Özay
{"title":"A Rare Case Report of Penile Necrosis Successfully Treated With Early Hyperbaric Oxygen Treatment.","authors":"İbrahim Ethem Akın, Mustafa Özay","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Warfarin is a widely used oral anticoagulant for the treatment of thromboembolic disorders. Warfarin-induced skin necrosis (WISN), a serious but rare complication, typically affects the breasts, hips, and abdomen. Penile necrosis, however, has been reported only in exceptionally rare cases.</p><p><strong>Case report: </strong>In this report, we present the successful outcome of early hyperbaric oxygen treatment (HBO₂) in a patient who developed glans penis necrosis during warfarin treatment and was subsequently diagnosed with protein C deficiency. The patient underwent nine HBO₂ sessions initiated early in the disease course and achieved full recovery without tissue loss.</p><p><strong>Discussion: </strong>To our knowledge, this is the first reported case in which HBO₂ was used as part of a combination treatment for penile necrosis in a patient with protein C deficiency. Hyperbaric oxygen treatment may represent an effective therapeutic option in rare cases of warfarin-associated penile necrosis.</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"53 2","pages":"291-294"},"PeriodicalIF":0.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148347053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hyperbaric Oxygen Treatment for Enhancing Athletic Recovery: A Systematic Review and Meta-Analysis. 高压氧治疗促进运动恢复:系统回顾和荟萃分析。
IF 0.6 4区 医学
Undersea and Hyperbaric Medicine Pub Date : 2026-02-01
Shrinit Babel, Gerardo Bosco, Enrico Camporesi
{"title":"Hyperbaric Oxygen Treatment for Enhancing Athletic Recovery: A Systematic Review and Meta-Analysis.","authors":"Shrinit Babel, Gerardo Bosco, Enrico Camporesi","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Hyperbaric oxygen treatment (HBO₂) uses increased atmospheric pressure and fractional oxygen to enhance tissue oxygen delivery. HBO₂ has gained attention as a tool for athletic recovery and performance, but past reviews in the literature are limited or inconclusive. This systematic review and meta-analysis aim to provide an update and assess the effect of HBO₂ on athletic recovery.</p><p><strong>Methods: </strong>Literature searches were performed across PubMed, Cochrane Central, Google Scholar, and Embase (January 1, 2015-September 15, 2024), following PRISMA guidelines. Studies included healthy athletes undergoing HBO₂ to assess athletic performance, metabolic recovery, and physiological responses. Quality assessment was performed using Cochrane's risk of bias tools (ROB2 and ROBINS-1). A meta-analysis with subgroup analyses by age, body mass index, and body fat mass percentage was conducted, along with a meta-regression examining HBO₂ protocol characteristics and outcomes.</p><p><strong>Results: </strong>Eleven met the eligibility criteria; six studies were included in the meta-analysis. The meta-analysis showed that HBO₂ significantly reduced post-recovery blood lactate levels (effect size: -1.71; 95% CI: -3.10 to -0.32). Subgroup analysis revealed that younger athletes and those with lower fat mass receiving HBO₂ exhibited significant reductions in post-recovery lactate levels. Meta-regression was inconclusive but suggested treatment effect heterogeneity based on HBO₂ protocol characteristics. HBO₂ showed limited application in short-term power output and force production.</p><p><strong>Discussion: </strong>Hyperbaric oxygen treatment is an efficient method for improving athletic performance, particularly by reducing post-exercise lactate levels, thereby supporting faster metabolic recovery. Future studies should focus on standardized protocols, diverse populations, and long-term outcomes to better understand HBO₂'s potential in orthopedics and sports medicine.</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"53 2","pages":"305-318"},"PeriodicalIF":0.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148347074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hyperbaric Oxygen Treatment for Arterial Gas Embolism With Transient Cortical Blindness Following Intravenous Ozone Therapy: A Case Report. 高压氧治疗静脉臭氧治疗后动脉气体栓塞伴一过性皮质性失明1例。
IF 0.6 4区 医学
Undersea and Hyperbaric Medicine Pub Date : 2026-02-01
Som Singh, Joseph Nevarez
{"title":"Hyperbaric Oxygen Treatment for Arterial Gas Embolism With Transient Cortical Blindness Following Intravenous Ozone Therapy: A Case Report.","authors":"Som Singh, Joseph Nevarez","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Cerebral arterial gas embolism (CAGE) is a rare but potentially fatal condition that can occur when air enters the arterial circulation.</p><p><strong>Case report: </strong>This case report describes a 64-year-old female patient who experienced a sudden onset of left lower extremity weakness and bilateral vision loss following a session of intravenous ozone therapy. Initial diagnostic imaging did not reveal any acute abnormalities. However, her clinical presentation was consistent with CAGE. She was initially administered emergent hyperbaric oxygen (HBO₂) at 2.8 ATA, followed by additional sessions at 2.0 ATA, which led to progressive symptomatic improvement and full resolution of her visual and motor deficits.</p><p><strong>Discussion: </strong>This case highlights the importance of recognizing the potential complications of intravenous ozone therapy, including CAGE. Hyperbaric oxygen treatment should be considered an option for patients with AGE following this procedure.</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"53 2","pages":"243-246"},"PeriodicalIF":0.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148347089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mixed Compartment Syndromes and Neuropathy Resolution With Hyperbaric Oxygen. 混合性筋膜室综合征和高压氧治疗神经病变。
IF 0.6 4区 医学
Undersea and Hyperbaric Medicine Pub Date : 2026-02-01
Michael Strauss, Arielle Sass, Katherine Wilson, Stuart Miller
{"title":"Mixed Compartment Syndromes and Neuropathy Resolution With Hyperbaric Oxygen.","authors":"Michael Strauss, Arielle Sass, Katherine Wilson, Stuart Miller","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Skeletal muscle compartment syndrome (SMCS) and exertional compartment syndrome (ECS) are two distinct conditions. This case report describes a situation in which both conditions resulted from the same triggering events. The importance of this case lies in the fact that the residual neuropathy associated with the SMCS resolved after a single hyperbaric oxygen (HBO₂) treatment.</p><p><strong>Case report: </strong>This report was generated from a retrospective analysis of the patient's combined compartment syndromes, SMCS and ECS, residual functional deficit, and resolution of the latter with HBO₂ treatment. Severe leg pain developed after two strenuous back-to-back ballet and gymnastics sessions. Similar leg pains of lesser severity had occurred previously but always resolved after the activity was stopped. During this episode, the pain subsided; however, the next day, the patient began to walk with a steppage gait. The athlete received HBO₂ treatment, which restored her peroneal nerve function. Subsequently, the patient underwent an ECS evaluation, bilateral leg fasciotomies, and returned to athletic activities without symptoms.</p><p><strong>Discussion: </strong>A residual nerve palsy can result from an SMCS. This symptom, combined with the rapid resolution of pain symptoms consistent with an ECS, suggests that both problems resulted from the same cause. The delayed onset of the drop foot was attributed to the self-perpetuating cycle of ischemia and edema associated with the lag phase of the SMCS. The resolution of the peroneal nerve palsy with HBO₂ treatment adds additional validation for the roles of HBO₂ in SMCS.</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"53 2","pages":"227-234"},"PeriodicalIF":0.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148347102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mild and Traditional Hyperbaric Oxygenation: Clinical Uses and Safety Considerations. 温和和传统高压氧合:临床应用和安全性考虑。
IF 0.6 4区 医学
Undersea and Hyperbaric Medicine Pub Date : 2026-02-01
Kelly Johnson-Arbor
{"title":"Mild and Traditional Hyperbaric Oxygenation: Clinical Uses and Safety Considerations.","authors":"Kelly Johnson-Arbor","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Unlike traditional hyperbaric oxygen treatment, which involves the inhalation of 100% oxygen by individuals enclosed in a pressurized treatment chamber at greater than sea level, mild hyperbaric oxygen treatment is performed in a pressurized chamber using shallower treatment depths and lower oxygen concentrations.</p><p><strong>Methods: </strong>This narrative review examines the physiological differences between mild and traditional hyperbaric oxygen treatment, the clinical uses of mild hyperbaric oxygen treatment, and the safety considerations of both treatment modalities.</p><p><strong>Results: </strong>The systemic hyperoxia induced by traditional hyperbaric oxygen treatment promotes wound healing but is associated with adverse events, including oxygen free radical damage. Mild hyperbaric oxygen treatment may benefit peripheral microcirculation, parasympathetic activity, and metabolism but has not been studied extensively as a wound treatment modality. Due to the lower oxygen concentrations used in mild hyperbaric oxygen treatment, the risk of oxidative damage may be lower with this treatment than with traditional hyperbaric oxygenation. However, both mild and traditional hyperbaric oxygenation are associated with potentially life-threatening adverse events, including chamber explosion and/or fire. Careful adherence to safety standards may reduce the occurrence risk of such incidents, but compliance with those standards is not universally mandated and may vary among facilities.</p><p><strong>Discussion: </strong>Traditional and mild hyperbaric oxygen treatment differ in physiology and clinical uses. Both treatments are associated with significant risks, but adherence to safety standards may reduce the incidence of adverse events and optimize patient care.</p>","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"53 2","pages":"247-254"},"PeriodicalIF":0.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148347063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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