Zeitschrift Fur Die Gesamte Neurologie Und Psychiatrie最新文献

{"title":"Die Behandlung der ADHS im Erwachsenenalter mit retardiertem Methylphenidat","authors":"E. Ahlers","doi":"10.1055/s-0038-1672291","DOIUrl":"https://doi.org/10.1055/s-0038-1672291","url":null,"abstract":"Zusammenfassung Die Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung (ADHS) im Erwachsenenalter ist mit verhaltensbezogenen und psychopharmakologischen Maßnahmen symptomatisch behandelbar. Die Ätiologie der Störung ist noch nicht zur Gänze geklärt, wobei genetische Faktoren einen großen Stellenwert einnehmen. Neurobiologisch wird ein Defizit dopaminerger und noradrenerger Funktionen modellhaft angenommen. Zur pharmakologischen Behandlung stehen mehrere Substanzen zur Verfügung. Zugelassen sind aktuell in Deutschland zur Neueinstellung im Erwachsenenalter retardierte Methylphenidate (Medikinet® adult, Ritalin® adult) und Atomoxetin (Strattera®). Eine Behandlung mit Methylphenidat retard gilt als erste Wahl. Methylphenidat wird dabei die Wirkung im Sinne eines starken Dopamin- und Noradrenalin-Wiederaufnahmehemmers als ursächlich für den therapeutischen Effekt zugeschrieben. Unerwünschte Wirkungen in der Behandlung mit Methylphenidat ergeben sich vordringlich aus den sympathomimetischen peripheren Effekten. An ein Missbrauchspotenzial und mögliche depressiogene Effekte sollte gedacht werden. Daten aus Langzeitstudien lassen bei guter Verträglichkeit auf eine zuverlässige positive Wirkung auf die Kernsymptomatik, den Komorbiditätsstatus sowie auf assoziierte Probleme bei ADHS schließen. Es besteht weiterhin großer Forschungsbedarf was die Ursachen der Störung sowie die genaue Wirkungsweise der Substanzen angeht.","PeriodicalId":49348,"journal":{"name":"Zeitschrift Fur Die Gesamte Neurologie Und Psychiatrie","volume":"40 1","pages":"164 - 170"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87188300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Schizophrenia research priorities from the viewpoint of patients/relatives","authors":"B. Johnson","doi":"10.1055/s-0038-1672289","DOIUrl":"https://doi.org/10.1055/s-0038-1672289","url":null,"abstract":"5. Millan MJ, Agid Y, Brüne M, Bullmore ET, Carter CS, Clayton NS, Young LJ (2012). Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy. Nature Reviews Drug Discovery 2012; 11(2): 141–168. http://doi.org/10.1038/nrd3628 6. Söderlund J, Wicks S, Jörgensen L, Dalman C. Comparing cohort incidence of schizophrenia with that of bipolar disorder and affective psychosis in individuals born in Stockholm County 2015; 1955–1967. Psychological Medicine, 45(16), 3433–9. http://doi.org/10.1017/S0033291715001336 7. Turner DT, van der Gaag M, Karyotaki E, Cuijpers P. Psychological interventions for psychosis: a meta-analysis of comparative outcome studies. The American Journal of Psychiatry 2014; 171(5): 523–538. Retrieved from http://europepmc.org/abstract/ MED/24525715 8. van den Heuvel MP, Sporns O. Rich-club organization of the human connectome. The Journal of Neuroscience 2011; 31(44): 15775–15786. http://doi.org/10.1523/JNEUROSCI.3539–11.2011 9. Wittchen H-U, Knappe S, Andersson G, Araya R, Banos Rivera RM, Barkham M, Schumann G. The need for a behavioural science focus in research on mental health and mental disorders. International Journal of Methods in Psychiatric Research 2014; 23(S1): 28–40. http://doi.org/10.1002/mpr.1409 10.Wooding S, Pollitt A, Castle-Clarke S, Cochrane G, Diepeveen S, Guthrie S, Grant J. Mental Health Retrosight: Understanding the returns from research (lessons from schizophrenia). Santa Monica, CA 2013. 11.Wykes T, Haro JM, Belli SR, Obradors-Tarragó C, Arango C, AyusoMateos JL, Wittchen H-U. Mental health research priorities for Europe. The Lancet. Psychiatry 2015; 2(11): 1036–1042. http://doi.org/10.1016/S2215–0366(15)00332–6 12.Wykes T, Steel C, Everitt B, Tarrier N. Cognitive Behavior Therapy for Schizophrenia: Effect Sizes, Clinical Models, and Methodological Rigor. Schizophrenia Bulletin 2008; 34(3): 523–537. http://doi.org/10.1093/schbul/sbm114 13.Dayalu P, Chou KL. Antipsychotic-induced extrapyramidal symptoms and their management. Expert Opinion on Pharmacotherapy 2008; 9(9): 1451–1462. 14. Lazarus JH. Lithium and thyroid. Best Practice & Research: Clinical Endocrinology & Metabolism 2009; 23(6): 723–733. http://doi.org/10.1016/j.beem.2009.06.002","PeriodicalId":49348,"journal":{"name":"Zeitschrift Fur Die Gesamte Neurologie Und Psychiatrie","volume":"65 1","pages":"161 - 162"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85652923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding walkability and walking rates in Berlin: an urban form and street pattern comparison","authors":"Alvaro Valera Sosa, C. Nickl-Weller","doi":"10.1055/s-0038-1670123","DOIUrl":"https://doi.org/10.1055/s-0038-1670123","url":null,"abstract":"Summary Background: This descriptive study provides information indicative of the interaction between physical features of neighbourhood environments with health behaviours such as walking and biking which consequently affect disease rates related to lifestyle. Aim: Through a summary of systematic observations at two urban scales, the macro and mesolevels, a neighbourhood comparison was realized in Berlin, Germany, to explore how urban forms and street patterns can support walking or biking, or not, despite seasonal variations, socio-economic status, cultural backdrop or individual decisions to walk. For this study, a conceptual evaluation framework was conceived and structured to assess secondary data from public databases, conveniently decreasing time and costs. Result: The framework and preliminary results of the work aim to be a significant endeavour in promoting transdisciplinarity among researchers and practitioners mainly from public health, architecture, urban planning and design fields.","PeriodicalId":49348,"journal":{"name":"Zeitschrift Fur Die Gesamte Neurologie Und Psychiatrie","volume":"39 1","pages":"79 - 87"},"PeriodicalIF":0.0,"publicationDate":"2016-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74648570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erhöhte Stressvulnerabilität bei Großstadtbewohnern","authors":"F. Lederbogen, A. Meyer-Lindenberg","doi":"10.1055/s-0038-1670121","DOIUrl":"https://doi.org/10.1055/s-0038-1670121","url":null,"abstract":"Zusammenfassung Hintergrund: Psychische Erkrankungen, insbesondere Schizophrenie, Depression und Angsterkrankungen, treten bei Bewohnern großer Städte häufiger auf als bei Menschen, die in kleinen Städten, Dörfern oder ländlicher Umgebung leben. Es gibt gute Argumente für die Annahme, dass der Faktor „urbane Umgebung“ im Zusammenwirken mit der genetischen Disposition eine kausale Rolle bei der Risikoerhöhung spielt. Als risikoerhöhendes wirksames Agens der urbanen Umgebung favorisieren viele Experten soziale Stressoren wie soziale Isolation oder fehlende soziale Unterstützung. Diese Annahme wird durch aktuelle Forschungsergebnisse der Neurowissenschaft gestützt, die eine höhere Aktivierung bestimmter Hirnareale unter sozial-evaluativem Stress bei Menschen urbaner Herkunft nachweisen. Diese Befunde sprechen für eine höhere Stressvulnerabilität von Großstadtbewohnern. Ergebnis: Die betroffenen Hirnstrukturen spielen eine wesentliche Rolle bei der Stressverarbeitung, sind aber auch bei der Genese der oben genannten Erkrankungen beteiligt. Der Aufenthalt in der Natur hat nach neuesten Daten eine ausgleichende Wirkung auf diese Hirnstrukturen. Diese Befunde unterstreichen die Bedeutung psychosozialer Stressoren im urbanen Raum, aber auch die einer fehlenden natürlichen Umgebung.","PeriodicalId":49348,"journal":{"name":"Zeitschrift Fur Die Gesamte Neurologie Und Psychiatrie","volume":"180 1","pages":"65 - 69"},"PeriodicalIF":0.0,"publicationDate":"2016-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73169753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depression und Begleiterkrankungen: Agomelatin: hohe Response-/Remissionsraten auch bei Komorbiditäten","authors":"A. Ameri","doi":"10.1055/S-0038-1670127","DOIUrl":"https://doi.org/10.1055/S-0038-1670127","url":null,"abstract":"","PeriodicalId":49348,"journal":{"name":"Zeitschrift Fur Die Gesamte Neurologie Und Psychiatrie","volume":"27 1","pages":"106 - 107"},"PeriodicalIF":0.0,"publicationDate":"2016-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83412216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aus Forschung und Industrie","authors":"","doi":"10.1055/s-0038-1670131","DOIUrl":"https://doi.org/10.1055/s-0038-1670131","url":null,"abstract":"","PeriodicalId":49348,"journal":{"name":"Zeitschrift Fur Die Gesamte Neurologie Und Psychiatrie","volume":"24 1","pages":"109 - 110"},"PeriodicalIF":0.0,"publicationDate":"2016-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81761397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychische Gesundheitsversorgung von Flüchtlingen","authors":"W. Gaebel, P. Falkai, N. Sartorius, J. Zielasek","doi":"10.1055/S-0038-1670118","DOIUrl":"https://doi.org/10.1055/S-0038-1670118","url":null,"abstract":"Introduction: The current refugee situation in Europa also leads to an increasing number of people with mental disorders. Which measures need to be taken to ascertain adequate mental healthcare for refugees during and after fleeing from their home countries? Methods: Review of the current tasks, areas of action and future challenges of refugee mental healthcare. Results: Refugee healthcare poses new challenges for the receiving and the transit countries. Besides dealing with the acute refugee situation, long term aspects of mental and general healthcare for refugees need to be considered. This will also include the reconstruction of the healthcare systems in the countries of origin of refugees.","PeriodicalId":49348,"journal":{"name":"Zeitschrift Fur Die Gesamte Neurologie Und Psychiatrie","volume":"45 1","pages":"58 - 58"},"PeriodicalIF":0.0,"publicationDate":"2016-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87554221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urbanisierung und psychische Gesundheit","authors":"P. Falkai, A. Meyer-Lindenberg","doi":"10.1055/S-0038-1670119","DOIUrl":"https://doi.org/10.1055/S-0038-1670119","url":null,"abstract":"","PeriodicalId":49348,"journal":{"name":"Zeitschrift Fur Die Gesamte Neurologie Und Psychiatrie","volume":"44 1","pages":"60 - 60"},"PeriodicalIF":0.0,"publicationDate":"2016-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89899820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Manuskriptrichtlinien","authors":"","doi":"10.1055/s-0038-1670134","DOIUrl":"https://doi.org/10.1055/s-0038-1670134","url":null,"abstract":"","PeriodicalId":49348,"journal":{"name":"Zeitschrift Fur Die Gesamte Neurologie Und Psychiatrie","volume":"1 1","pages":"112 - 112"},"PeriodicalIF":0.0,"publicationDate":"2016-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83119800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Methadon-Tabletten vermitteln Gefühl der Sicherheit","authors":"S. Heinzl","doi":"10.1055/S-0038-1670128","DOIUrl":"https://doi.org/10.1055/S-0038-1670128","url":null,"abstract":"","PeriodicalId":49348,"journal":{"name":"Zeitschrift Fur Die Gesamte Neurologie Und Psychiatrie","volume":"17 1","pages":"108 - 108"},"PeriodicalIF":0.0,"publicationDate":"2016-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85820017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}