Dimitrios Strepkos, Michaella Alexandrou, Pedro E P Carvalho, Eleni Kladou, Nick Williford, Olga Mastrodemos, Bavana V Rangan, Yader Sandoval, Emmanouil S Brilakis
{"title":"Quantification of myocardial mass using coronary computed tomography angiography in bifurcation PCI and association with outcomes.","authors":"Dimitrios Strepkos, Michaella Alexandrou, Pedro E P Carvalho, Eleni Kladou, Nick Williford, Olga Mastrodemos, Bavana V Rangan, Yader Sandoval, Emmanouil S Brilakis","doi":"10.25270/jic/25.00382","DOIUrl":"10.25270/jic/25.00382","url":null,"abstract":"<p><strong>Objectives: </strong>To determine if quantification of the myocardial mass supplied by a side branch (SB) could be predictive of bifurcation percutaneous coronary intervention (PCI) outcomes.</p><p><strong>Methods: </strong>The authors examined the characteristics and outcomes of 73 patients (81 lesions) who underwent bifurcation PCI and had coronary computed tomography angiography (CCTA) angiography based computed flow-based calculation of myocardial mass at risk within 6 months prior.</p><p><strong>Results: </strong>The lesions analyzed were complex with high V-RESOLVE scores (12.0, 95%, interquartile range [IQR]: 9.0, 13.5). Provisional stenting was used in 67.9%, 2-stent techniques in 32.1%, and conversion from provisional to 2-stent stenting was performed in 11.1% of the lesions. The main vessel (MV) supplied 30.0% (IQR: 24.0%, 36.0%) and the SB supplied 10.0% (IQR: 7.0%, 13.0%) of the myocardium. Technical success was 94.9%. Major adverse cardiovascular events (MACE) occurred in 5.5% of the patients and SB occlusion (SBO) in 12.3% of the lesions. The ratio of SB to MV myocardial mass supply (SB/MV) was not associated with technical success (odds ratio [OR], 11.00; 95% confidence interval [CI], 0.01, 18.79; P = .500) or MACE (OR, 0.02; 95% CI, 0.00, 18.20; P = .300), but was associated with SBO (OR, 6.02*10-6; 95% CI, 2.42*10-10, 0.15; P = .020). SB/MV was normally distributed (W = 0.99, P = .467) with a mean of 0.35 (95% CI, 0.31, 0.38). In lesions where SBO occurred, V-RESOLVE scores were higher (16.0 vs 12.0, P = .017) and the SB/MV ratio was lower (0.22 vs 0.35, P = .007).</p><p><strong>Conclusions: </strong>Myocardial mass derived from CT analysis can help assess the risk of SBO after bifurcation PCI.</p>","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147787200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mireia Martínez, Paula Vela, Juan Casanova-Sandoval, Kristian Rivera
{"title":"Intravascular ultrasound-guided management of early stent thrombosis secondary to coronary intramural hematoma.","authors":"Mireia Martínez, Paula Vela, Juan Casanova-Sandoval, Kristian Rivera","doi":"10.25270/jic/26.00019","DOIUrl":"10.25270/jic/26.00019","url":null,"abstract":"","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146068110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicolas Bradt, Maxim Verlee, Christophe Borin, Hans Vandekerckhove, Laurens De Vos
{"title":"Septal coronary artery fistula after implantation of a left bundle branch area pacemaker.","authors":"Nicolas Bradt, Maxim Verlee, Christophe Borin, Hans Vandekerckhove, Laurens De Vos","doi":"10.25270/jic/26.00017","DOIUrl":"10.25270/jic/26.00017","url":null,"abstract":"","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146094732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tara Seirafi, Jeremy Y Levett, Areesha Moiz, Tetiana Zolotarova, Kristian B Filion, Adelina Dobromir Angheluta, Pauline Reynier, Mark J Eisenberg
{"title":"Extracorporeal versus conventional cardiopulmonary resuscitation for out-of-hospital cardiac arrests.","authors":"Tara Seirafi, Jeremy Y Levett, Areesha Moiz, Tetiana Zolotarova, Kristian B Filion, Adelina Dobromir Angheluta, Pauline Reynier, Mark J Eisenberg","doi":"10.25270/jic/25.00405","DOIUrl":"10.25270/jic/25.00405","url":null,"abstract":"<p><strong>Objectives: </strong>It remains unclear whether extracorporeal cardiopulmonary resuscitation (ECPR) is more efficacious than conventional cardiopulmonary resuscitation (CPR) at improving survival with favorable neurological outcomes among patients with out-of-hospital cardiac arrests (OHCA). The authors sought to determine the efficacy of ECPR vs conventional CPR among patients with OHCA in the pre-hospital setting.</p><p><strong>Methods: </strong>The authors searched MEDLINE, EMBASE, and the Cochrane Library for randomized controlled trials (RCTs) comparing ECPR with conventional CPR for patients with OHCA. The primary outcome was survival with a favorable neurological outcome at 6-month follow-up. Count data were pooled across trials through random-effects models with inverse variance weighting to estimate risk ratios (RRs) and 95% confidence intervals (CIs).</p><p><strong>Results: </strong>A total of 3 RCTs (n = 420) were included. Most patients (85%) were male, and the mean/median age ranged from 54 to 59 years. At 6 months, 28.4% of the patients randomized to ECPR survived with favorable neurological outcomes compared with 18.6% of the patients randomized to conventional CPR (RR, 1.47; 95% CI, 0.43-5.09). Similar results were obtained for survival at hospital discharge (RR, 1.35; 95% CI, 0.35-5.19). Risk of Bias 2 analysis indicated low risk in 1 trial and some concerns in others.</p><p><strong>Conclusions: </strong>ECPR may be associated with improved survival with favorable neurological outcomes at 6 months compared to conventional CPR for the treatment of OHCA. However, the available evidence remains inconclusive, and additional trials are needed to definitively assess the efficacy of ECPR compared to conventional CPR for OHCA.</p>","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147845052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jeong Hwan J Kim, Leili Pourafkari, Jonathan Lalezari, Ali Sovari
{"title":"Right internal jugular pulsed field ablation for atrial fibrillation in a patient with an inferior vena cava filter.","authors":"Jeong Hwan J Kim, Leili Pourafkari, Jonathan Lalezari, Ali Sovari","doi":"10.25270/jic/26.00023","DOIUrl":"10.25270/jic/26.00023","url":null,"abstract":"","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146094721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mechanical reperfusion of subocclusive plaque erosion: 30-month outcome of an optical coherence tomography-guided stentless strategy.","authors":"Kaïs Ouerghi, Tahar Lazizi, Victor Mateus","doi":"10.25270/jic/26.00020","DOIUrl":"10.25270/jic/26.00020","url":null,"abstract":"","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146068161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The prevalence of cardiac symptoms in Ehlers-Danlos syndrome and hypermobility spectrum disorder: a pilot study.","authors":"Ermin Tale, Riya Kaushal, Bilal Niazi, Katie Nikishina, Amy Chen, Bernadette Riley, Todd J Cohen","doi":"10.25270/jic/25.00395","DOIUrl":"10.25270/jic/25.00395","url":null,"abstract":"<p><strong>Objectives: </strong>The authors compared palpitations, presyncope, syncope, and postural orthostatic tachycardia syndrome (POTS) prevalence among patients with hypermobile Ehlers-Danlos syndrome (hEDS) and hypermobility spectrum disorder (HSD).</p><p><strong>Methods: </strong>A retrospective analysis of patients referred for cardiac evaluation at the New York Institute of Technology Ehlers-Danlos Syndrome/Hypermobility Treatment Center between January 2019 and November 2023 was conducted. hEDS and HSD patients underwent cardiac evaluation and were stratified by median age into younger (<35 years) and older (≥35 years) groups. Symptom prevalence was compared between hypermobile patients overall and by age cohort. Data were presented as mean ± SD; P < .05 was considered statistically significant.</p><p><strong>Results: </strong>One hundred-nine patients (75 hEDS, 34 HSD) underwent cardiac evaluation: 75 hEDS (71 females/4 males; age 33.9 + 11.6 years) and 34 HSD (29 females/ 5 males; age 40.0 + 13.8 years). POTS (48% vs 23.5%, P = .016) was significantly more prevalent in the hEDS group; palpitations, presyncope, and syncope were common in both groups. No significant differences were observed in Cohort 1 (age less than 35 years). In Cohort 2 (age ≥35 years), presyncope (100% vs 82.6%, P = .04) differed; palpitations, syncope, and POTS were similar. POTS was prevalent in patients younger than 35 years with hEDS (58.3% vs 29.6%, P = .022) and HSD (45.5% vs 13.0%, P = .042).</p><p><strong>Conclusions: </strong>Patients with h EDS exhibited greater symptoms than HSD patients, and symptoms were particularly more pronounced with age. POTS prevalence decreased with age in both groups. Larger prospective studies are needed to explore underlying mechanisms.</p>","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147845092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pablo Vidal-Calés, Quentin Battistolo, Maxim Ruel, Alicia Prieto-Lobato, Pedro Cepas-Guillen, Xavier Freixa, Josep Rodés-Cabau
{"title":"Early discontinuation of antithrombotic therapy following left atrial appendage closure: a systematic review and meta-analysis.","authors":"Pablo Vidal-Calés, Quentin Battistolo, Maxim Ruel, Alicia Prieto-Lobato, Pedro Cepas-Guillen, Xavier Freixa, Josep Rodés-Cabau","doi":"10.25270/jic/26.00142","DOIUrl":"https://doi.org/10.25270/jic/26.00142","url":null,"abstract":"<p><strong>Objectives: </strong>Optimal postprocedural antithrombotic management after left atrial appendage closure (LAAC) remains undefined, particularly in patients with high bleeding risk. Early complete cessation (<6 months) of antithrombotic therapy (AT) following LAAC is increasingly adopted, yet supportive evidence is limited. This study sought to evaluate the safety of early (<6 months) complete discontinuation of AT after LAAC.</p><p><strong>Methods: </strong>A systematic review and meta-analysis of observational studies was conducted. PubMed and Scopus were searched through September 2025. The primary endpoint was stroke events; secondary endpoints included all-cause mortality, major bleeding, and device-related thrombus (DRT). Random-effects models were used to calculate pooled risk ratios (RRs). Subgroup and sensitivity analyses were performed.</p><p><strong>Results: </strong>Seven studies including 1841 patients (529 with early AT cessation) were analyzed. Patients undergoing early AT discontinuation exhibited high baseline thromboembolic and bleeding risk, and most of them (67%) had prior bleeding events. Over a weighted mean follow-up of 19.2 months, early discontinuation of AT was not associated with increased risk of stroke (RR, 1.04; 95% CI, 0.40-2.66), all-cause death (RR, 1.03; 95% CI, 0.49-2.17), major bleeding (RR, 1.22; 95% CI, 0.75-2.01), or DRT (RR, 0.49; 95% CI, 0.14-1.73). No significant differences were observed between very early (<1 month) and early (<6 months) cessation strategies.</p><p><strong>Conclusions: </strong>Among high-bleeding-risk patients undergoing LAAC, early complete discontinuation of AT was not associated with an increased risk of thromboembolic events or death during mid-term follow-up. These results support the potential ischemic safety of early antithrombotic cessation in carefully selected patients and highlight the need for definite evidence from randomized trials.</p>","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148621886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katherine Rand, Roberto Valdovinos, Cynthia Herrington, Neil D Patel
{"title":"Device occlusion of giant pulmonary artery aneurysm in a 12-year-old with Behçet's disease.","authors":"Katherine Rand, Roberto Valdovinos, Cynthia Herrington, Neil D Patel","doi":"10.25270/jic/26.00239","DOIUrl":"https://doi.org/10.25270/jic/26.00239","url":null,"abstract":"","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148621895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}