International Journal of Lower Extremity Wounds最新文献

RETRACTED: The Leg Subcutaneous Tissue Calcification and Venous Ulcer-a Case Series. 撤下：小腿皮下组织钙化和静脉溃疡-病例系列。

IF 2.2 4区医学

International Journal of Lower Extremity Wounds Pub Date : 2026-09-01 Epub Date: 2022-06-05 DOI: 10.1177/15347346221106578

Zhoupeng Wu, Yukui Ma, Xiaorong Wen

{"title":"RETRACTED: The Leg Subcutaneous Tissue Calcification and Venous Ulcer-a Case Series.","authors":"Zhoupeng Wu, Yukui Ma, Xiaorong Wen","doi":"10.1177/15347346221106578","DOIUrl":"10.1177/15347346221106578","url":null,"abstract":"Ultrasonography of patients with venous ulcers showed subcutaneous tissue calcification （STC）in some patients. However, calcification is rarely included in venous ulcer-related changes. The aim of this study was to evaluate the prevalence and morphological changes of STC in patients with ultrasonographically diagnosed with venous ulcers. A total of 80 legs of 40 patients with venous ulcers (28 women and 12 men, mean age 48 years, range 18-83 years) were included in this study. After ultrasonographic evaluation of the patient's deep, superficial, and perforating veins, continue to use ultrasonography to examine the patient's subcutaneous tissue for the presence of STC. According to the CEAP (Clinical, Etiological, Anatomical, Pathophysiological) classification of Group C, 18 legs were classified as C5 and 62 as C6. STC was present in 38 of the 80 legs, most of which were patients classified as C6.STC are easily detected by ultrasound, especially in the injured area of the leg in C6 patients. STC may be associated with chronic inflammation of the subcutaneous tissue. It is recommended to remove it from the ulcer bed to promote ulcer healing and prevent recurrence. Further studies are needed to determine its prognostic significance and other possible clinical implications.","PeriodicalId":49181,"journal":{"name":"International Journal of Lower Extremity Wounds","volume":" ","pages":"1059-1062"},"PeriodicalIF":2.2,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9556910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Elephant in the Room. 房间里的大象。

IF 1.5 4区医学

International Journal of Lower Extremity Wounds Pub Date : 2026-06-01 Epub Date: 2023-07-31 DOI: 10.1177/15347346231191229

Alberto Piaggesi, Roberto Ferraresi, Mauro Gargiulo

引用次数: 0

Prescribing Home Digital Thermometry Coupled with Activity Dosing and Optimized Offloading to Prolong Diabetic Foot Remission: A Case Report. 家庭数字测温与活动剂量和优化卸载相结合，延长糖尿病足缓解期：病例报告。

IF 1.5 4区医学

International Journal of Lower Extremity Wounds Pub Date : 2026-06-01 Epub Date: 2023-07-04 DOI: 10.1177/15347346231184008

Malindu E Fernando, Virginie Blanchette, Stephanie L Woelfel, Alexandria Armstrong, Charles DuBourdieu, Laura Shin, David G Armstrong

{"title":"Prescribing Home Digital Thermometry Coupled with Activity Dosing and Optimized Offloading to Prolong Diabetic Foot Remission: A Case Report.","authors":"Malindu E Fernando, Virginie Blanchette, Stephanie L Woelfel, Alexandria Armstrong, Charles DuBourdieu, Laura Shin, David G Armstrong","doi":"10.1177/15347346231184008","DOIUrl":"10.1177/15347346231184008","url":null,"abstract":"People with a history of diabetic foot ulcers (DFUs) experience diminished health-related quality of life and are at a 40% annual risk of DFU recurrence. Due to a fear of DFU recurrence, people in DFU remission participate less in physical activity and moderate-intensity exercise when compared to people with diabetes who have not had wounds. There is novel evidence to suggest that too little activity during DFU remission contributes to only low magnitudes of repetitive tissue loading creating a higher susceptibility to skin trauma during inadvertent high-activity bouts. Conversely, a hasty return to too much activity could lead to rapid recurrence. There is now high-level evidence from multiple meta-analyses to indicate that home-based foot temperature monitoring, coupled with activity modification and daily inspection of the feet for impending signs of ulceration, could reduce the risk of ulcer recurrence by 50%. There is little evidence, however, to guide the decision-making regarding the appropriate quantity and frequency of physical activity during DFU remission and the acceptability from the patient perspective. This has resulted in limited uptake of this novel intervention in clinical practice. Earlier, we proposed that activity can be dosed for people in foot ulcer remission, just like insulin or medication is dosed. Here, we describe a patient-centered approach to implementing home foot temperature monitoring coupled with daily foot checks and dosage-based return to physical activity in a patient in DFU remission, including his perspective. We believe using such an approach could maximize ulcer-free days in remission, thereby improving quality of life.","PeriodicalId":49181,"journal":{"name":"International Journal of Lower Extremity Wounds","volume":" ","pages":"629-635"},"PeriodicalIF":1.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9803173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Usability of Different Methods to Assess and Improve Adherence to Therapeutic Footwear in Persons with the Diabetic Foot in Remission. A Systematic Review. 评估和改善糖尿病足缓解期患者治疗性鞋类依从性的不同方法的可用性。系统评价。

IF 1.5 4区医学

International Journal of Lower Extremity Wounds Pub Date : 2026-03-01 Epub Date: 2023-08-07 DOI: 10.1177/15347346231190680

Mateo López-Moral, Raúl J Molines-Barroso, María Herrera-Casamayor, Marta García-Madrid, Esther García-Morales, José Luis Lázaro-Martínez

{"title":"Usability of Different Methods to Assess and Improve Adherence to Therapeutic Footwear in Persons with the Diabetic Foot in Remission. A Systematic Review.","authors":"Mateo López-Moral, Raúl J Molines-Barroso, María Herrera-Casamayor, Marta García-Madrid, Esther García-Morales, José Luis Lázaro-Martínez","doi":"10.1177/15347346231190680","DOIUrl":"10.1177/15347346231190680","url":null,"abstract":"Therapeutic footwear (TF) has been demonstrated to decrease the rate of recurrence in patients in remission. TF adherence determines the real effect of such treatment and, therefore, an appropriate evaluation of TF adherence is critical to decrease recurrence. The aim of this systematic review was to determine the usability of different methods of assessing adherence to TF in patients with diabetic foot ulcers under remission. The search strategy retrieved 506 articles. Title and abstract review excluded 472, while the full-text review excluded an additional 18 articles because the included data did not meet the selection criteria. Finally, we included 16 articles in this systematic review. Six (37.5%) of the 16 studies combined objective (OM) and subjective methods (SM). Only five (31.25%) evaluated OM and six (37.5%) studies only evaluated SM. Objective methods (temperature sensor, activity monitor) and subjective methods (survey, questionnaire) have successfully been used in the literature to evaluate TF adherence. Objective methods provided accurate data, whereas subjective methods led to response bias or missing data. Methods of evaluation showed that patients use the TF more frequently outdoors and on weekdays than indoors or on the weekend. In conclusion, objective methods are the most usable way to measure adherence to TF.","PeriodicalId":49181,"journal":{"name":"International Journal of Lower Extremity Wounds","volume":" ","pages":"55-64"},"PeriodicalIF":1.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10319305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Implication of Peripheral Neuropathy on Unplanned Readmissions in Patients Hospitalized for Complicated Diabetic Foot Disease. 周围神经病变对合并糖尿病足病住院患者意外再入院的影响。

IF 1.5 4区医学

International Journal of Lower Extremity Wounds Pub Date : 2026-03-01 Epub Date: 2023-08-31 DOI: 10.1177/15347346231197885

Erwin Yii, Amos Au, Justin Bradley, Alan Saunder, Roger Bell, Ming K Yii

{"title":"Implication of Peripheral Neuropathy on Unplanned Readmissions in Patients Hospitalized for Complicated Diabetic Foot Disease.","authors":"Erwin Yii, Amos Au, Justin Bradley, Alan Saunder, Roger Bell, Ming K Yii","doi":"10.1177/15347346231197885","DOIUrl":"10.1177/15347346231197885","url":null,"abstract":"Introduction. Unplanned readmissions are common following discharge in patients after hospitalization for diabetic foot disease (DFD) complications. The aim of this study was to identify factors associated with readmissions in these high-risk patients, treated in a multidisciplinary setting and the implication of measures that could effectively reduce readmission rates. Methods. Patients presenting with DFDs admitted between 2015 and 2017 were studied retrospectively in a single-centre patient database. The demographics and clinical comorbidities were analyzed and comparison was made between 2 groups: patients readmitted within 30 days of discharge and those who did not require readmission. Multivariate analysis was performed to identify risk factors associated with readmissions. Results. In total, 340 patients were included. The unplanned readmission rate was 10.9%. More than half of readmissions (71%) were related to wound deterioration and infection. In the readmission group, the patients had lower body mass index, higher rate of osteomyelitis, lower rate of debridement, and evidence of peripheral vascular disease below the knee in the index admissions but these were not significant. In the multivariate analysis, peripheral neuropathy was the only significant risk associated with unplanned readmissions (odds ratio: 2.78, 95% confidence interval: 1.23-6.29, P = .014). Conclusion. This study demonstrates a significant association between peripheral neuropathy and unplanned readmissions. The implications of this nonmodifiable risk factor in reducing readmissions include all levels of patient care delivery such as adequate preparation for discharge and transition back into the community. Recognition and education in successful long-term offloading of insensate diabetic feet may help reduce rates of unplanned readmission.","PeriodicalId":49181,"journal":{"name":"International Journal of Lower Extremity Wounds","volume":" ","pages":"118-122"},"PeriodicalIF":1.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10185756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Angiolymphoid Hyperplasia With Eosinophilia Associated With Stasis Dermatitis. 血管淋巴样增生伴嗜酸性粒细胞增多伴瘀血性皮炎。

IF 1.5 4区医学

International Journal of Lower Extremity Wounds Pub Date : 2026-03-01 Epub Date: 2023-08-07 DOI: 10.1177/15347346231194111

Si-Yu Luo, Li-Jia Deng, Sheng Fang

引用次数: 0

Extracellular to Intracellular Water Ratio Determined by Bioimpedance is Associated with Mortality in Patients Admitted for Diabetic Foot Ulcers. 生物阻抗测定的细胞外与细胞内水分比与糖尿病足溃疡住院患者的死亡率相关。

IF 1.5 4区医学

International Journal of Lower Extremity Wounds Pub Date : 2026-03-01 Epub Date: 2023-06-15 DOI: 10.1177/15347346231173861

María Eugenia López-Valverde, Javier Aragón-Sánchez, Gerardo Víquez-Molina, Pilar Rodríguez Ortega

引用次数: 0

Microbiological and Clinical Characteristics of Infected Diabetic Foot Ulcers Managed in a Tertiary Level Diabetic Foot Service. 感染糖尿病足溃疡的微生物学和临床特征在三级糖尿病足服务管理。

IF 1.5 4区医学

International Journal of Lower Extremity Wounds Pub Date : 2026-03-01 Epub Date: 2023-06-01 DOI: 10.1177/15347346231178642

Cipriano Rossana, Marco Meloni, Laura Giurato, Jose Luis Lazaro-Martinez, Andreadi Aikaterini, Ruotolo Valeria, Alfonso Bellia, Davide Lauro, Luigi Uccioli

{"title":"Microbiological and Clinical Characteristics of Infected Diabetic Foot Ulcers Managed in a Tertiary Level Diabetic Foot Service.","authors":"Cipriano Rossana, Marco Meloni, Laura Giurato, Jose Luis Lazaro-Martinez, Andreadi Aikaterini, Ruotolo Valeria, Alfonso Bellia, Davide Lauro, Luigi Uccioli","doi":"10.1177/15347346231178642","DOIUrl":"10.1177/15347346231178642","url":null,"abstract":"The study aimed to evaluate the clinical and microbiological characteristics of diabetic foot infections (DFIs) in patients referring to a specialized diabetic foot service (DFS). The study is a retrospective observational study conducted in a single center, including patients who were referred for a new DFI. All patients were managed through a limb salvage protocol according to international guidelines. The following items were recorded: type of bacteria, presence of single or polymicrobial infection, and the antibiotic resistance. Overall, 268 patients were included. The mean age was 68.9 ± 10.9 years, 75% were male, and 97.2% had type 2 diabetes with a mean diabetes duration of 16 ± 9 years. One hundred thirty-nine (51.9%) DFU were ischemic, 120 (44.7%) patients had osteomyelitis, 107 (39.9%) had gangrene, 37 (13.9%) had phlegmon/abscess/cellulitis and 4 (1.5%) had necrotizing fasciitis. Among 370 bacteria isolated, gram positive were found in 207 (55.9%) cases, and gram negative in 163 (44.1%) cases. The higher rates of isolates were Staphylococcus aureus (32.9%), Pseudomonas aeruginosa (10.8%), and Enterococcus faecalis (8.9%). Polymicrobial infection was reported in 33.6% of cases and antibiotic resistance was recorded in 16.5% of isolates. Among them, 10.3% were methicillin-resistant S. aureus (MRSA). Antibiotic resistance was detected in 40.9% of cases in association with gangrene and osteomyelitis. The current study shows as polymicrobial infections and antibiotic resistance is frequently reported in DFIs, and antibiotic resistance was more associated with gangrene and osteomyelitis. Among bacteria reporting antimicrobial resistance, the highest rate was found for MRSA.","PeriodicalId":49181,"journal":{"name":"International Journal of Lower Extremity Wounds","volume":" ","pages":"74-80"},"PeriodicalIF":1.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9562452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prediction Interval in Meta-Analyses. meta分析的预测区间。

IF 1.5 4区医学

International Journal of Lower Extremity Wounds Pub Date : 2026-03-01 Epub Date: 2023-08-07 DOI: 10.1177/15347346231185615

Elena Christaina, Gregory Trypsianis, Miltos K Lazarides

引用次数: 0

The Role of Escin as a Topical Agent for Lymphedema Treatment in a Rat Model. Escin作为局部药物治疗大鼠淋巴水肿模型的作用。

IF 1.5 4区医学

International Journal of Lower Extremity Wounds Pub Date : 2026-03-01 Epub Date: 2023-08-22 DOI: 10.1177/15347346231195944

Hyung Hwa Jeong, Donggeun Kim, Taehyun Kim, HyunSuk Peter Suh, ChangSik John Pak, Jae Yong Jeon, Joon Pio Hong

{"title":"The Role of Escin as a Topical Agent for Lymphedema Treatment in a Rat Model.","authors":"Hyung Hwa Jeong, Donggeun Kim, Taehyun Kim, HyunSuk Peter Suh, ChangSik John Pak, Jae Yong Jeon, Joon Pio Hong","doi":"10.1177/15347346231195944","DOIUrl":"10.1177/15347346231195944","url":null,"abstract":"Escin, a naturally derived material isolated from horse chestnut, is used as an anti-inflammatory and anti-edema agent. This study aimed to evaluate its effects on lymphedema in a rat tail model. We divided the rats into five groups. The treatment groups received topical application of escin gel at concentrations of 20%, 10%, 2%, and 0.5% for 4 weeks. The fifth group served as a control. We performed volumetric (water displacement) tests, H&E staining, and LYVE-1 immunohistochemical staining, followed by statistical evaluation. All treatment groups showed significant volumetric reductions compared with the control group, but no significant differences were observed between the treatment groups. H&E staining showed a significant reduction in dermal thickness in the 20%, 10%, and 2% escin treatment groups compared to the control group. Within the treatment groups, the 2% escin group showed a significant difference compared with the 20% and 10% escin groups (p = 0.021 for both). LYVE-1 immunohistochemical staining revealed a significantly higher mean lymphatic vessel count in the 2% escin group compared with the 20%, 10%, and 0.5% escin-treated groups and the control group (p = 0.019, p = 0.025, p = 0.019, and p = 0.032 respectively). Topical escin applied to a rat tail model of acute lymphedema resulted in a significant reduction in tail volume, reduced dermal thickness, and increased lymphatic structures. The 2% escin concentration may be the optimal dose for improving lymphedema in this model. Further research is warranted to explore the clinical application of escin in patients with lymphedema.","PeriodicalId":49181,"journal":{"name":"International Journal of Lower Extremity Wounds","volume":" ","pages":"109-117"},"PeriodicalIF":1.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10047701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0