Negative Pressure Wound Therapy: Supra-Physiological or Just Physical Effects of Positive Pressure?

IF 1.5 4区医学 Q3 DERMATOLOGY

International Journal of Lower Extremity Wounds Pub Date : 2025-09-01 Epub Date: 2022-12-07 DOI:10.1177/15347346221144145

Valdas Macionis

引用次数: 0

Abstract

This communication provides a new insight into the unexplained physiology of beneficial effects of negative pressure wound therapy (NPWT). Possible mechanisms of beneficial effects of NPWT in failing replantation and free tissue transfer are discussed. Positive pressure generated by NPWT as well as its draining action creates exudate-free tight tissue-to-tissue interface, which may enhance neovascularization.

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负压伤口疗法：正压的超生理效应还是物理效应？

这篇通讯对负压伤口疗法（NPWT）有益效果的未知生理学提供了新的见解。文中讨论了负压疗法在失败的再植和游离组织转移中产生有益影响的可能机制。负压伤口疗法产生的正压及其引流作用可形成无渗出物的紧密组织-组织界面，这可能会促进血管新生。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Lower Extremity Wounds DERMATOLOGY-SURGERY

CiteScore

4.60

自引率

17.60%

发文量

审稿时长

>12 weeks

期刊介绍： The International Journal of Lower Extremity Wounds (IJLEW) is a quarterly, peer-reviewed journal publishing original research, reviews of evidence-based diagnostic techniques and methods, disease and patient management, and surgical and medical therapeutics for lower extremity wounds such as burns, stomas, ulcers, fistulas, and traumatic wounds. IJLEW also offers evaluations of assessment and monitoring tools, dressings, gels, cleansers, pressure management, footwear/orthotics, casting, and bioengineered skin. This journal is a member of the Committee on Publication Ethics (COPE).