International Journal of Lower Extremity Wounds最新文献_第10页

Rare Case of Pyoderma Gangrenosum in the Setting of PAPA Syndrome in a 12-Year-Old Child. 罕见的坏疽性脓皮病在PAPA综合征背景下的12岁儿童。

IF 1.7 4区医学

International Journal of Lower Extremity Wounds Pub Date : 2023-09-01 DOI: 10.1177/15347346211036023

Aminah Alhumam

{"title":"Rare Case of Pyoderma Gangrenosum in the Setting of PAPA Syndrome in a 12-Year-Old Child.","authors":"Aminah Alhumam","doi":"10.1177/15347346211036023","DOIUrl":"https://doi.org/10.1177/15347346211036023","url":null,"abstract":"We report on a 12-year-old boy who presented with an intermittently painful wound present for months without any tendency to heal after a slackline accident two years ago. A biopsy of the ulcer margin revealed epithelial hyperplasia, marked fibrosis, and vascular proliferation without evidence of vasculitis. Pretibial findings on the right side were a 3.8 × 3.1 cm fibrin-covered, flat ulcer with slight reddening of the surrounding area. Other findings were unremarkable with hypermobility of the wrists and finger joints. Local therapy with a foam dressing, topical steroid in the wound margin, and class II compression stockings showed no effect. The pediatric rheumatologist evaluated the ulcer with a camptodactyly of digit 5, subluxation of the wrists on both sides, and symmetric ulnar deviation. Elevated S100 as an isolated autoimmune phenomenon or concomitant with systemic autoimmune disease or autoinflammation (eg, Pyogenic sterile arthritis, pyoderma gangrenosum, and acne syndrome) was also observed. The therapy with oral steroids, initially 30 mg/day and gradual reduction in the course, only achieved a tissue bridge's formation with the same size extension of the ulcer. Unfortunately, the patient spontaneously developed a second ulcer on the left lateral malleolus, which is why the therapy was changed to dapsone 50 mg/day and tacrolimus in the wound margin after nine weeks. In the absence of success, further treatment with ciclosporin or tumor necrosis factor-alpha antibody therapy is planned in interdisciplinary cooperation.","PeriodicalId":49181,"journal":{"name":"International Journal of Lower Extremity Wounds","volume":"22 3","pages":"620-624"},"PeriodicalIF":1.7,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9909388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term Results After Autologous Fat Transfer for Treatment of Chronic Lower Extremity Wounds. 自体脂肪移植治疗慢性下肢创伤后的长期效果。

IF 1.7 4区医学

International Journal of Lower Extremity Wounds Pub Date : 2023-09-01 Epub Date: 2021-06-28 DOI: 10.1177/15347346211027684

Johannes Eschborn, Philipp Kruppa, Iakovos Georgiou, Manfred Infanger, Mojtaba Ghods

{"title":"Long-term Results After Autologous Fat Transfer for Treatment of Chronic Lower Extremity Wounds.","authors":"Johannes Eschborn, Philipp Kruppa, Iakovos Georgiou, Manfred Infanger, Mojtaba Ghods","doi":"10.1177/15347346211027684","DOIUrl":"10.1177/15347346211027684","url":null,"abstract":"Autologous fat transfer may offer a simple and effective treatment option for chronic wound patients, delivering adipose-derived stem cells, with potent regenerative attributes. Nevertheless, the clinical benefit has not yet been sufficiently demonstrated. A total of 39 wound patients were treated with autologous fat transfer (AFT) and matched with a control group, according to the identified confounding variables \"gender\" and \"method of defect closure.\" All data were acquired retrospectively. Primary outcome was \"wound closure\" and \"reduction of wound size.\"After a follow-up of 48 weeks, there was no significant difference in primary outcome (wound closure P = .54) between both groups. The relative wound reduction after fat transfer was 69.9% ± 42.7% compared to 53.4% ± 106.8% in the control group (P = .91). Subgroup analysis of all patients, healed by secondary intention, revealed an increased wound size reduction (P = .03) and wound closure rate (P = .20) in the case group after 12 weeks. No adverse events were recorded. Fat grafting can reduce the wound size if left to secondary healing and may be considered individually for reconstructive purposes. A repeated application of autologous fat might be beneficial due to a temporary effect.","PeriodicalId":49181,"journal":{"name":"International Journal of Lower Extremity Wounds","volume":"22 3","pages":"524-530"},"PeriodicalIF":1.7,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9915190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Suspicious Plantar Lesion-A Case Report of Angiosarcoma. 足底可疑病变-血管肉瘤1例报告。

IF 1.7 4区医学

International Journal of Lower Extremity Wounds Pub Date : 2023-09-01 DOI: 10.1177/15347346211028348

Ruijuan Wang, Jianjun Pi, Minli Zhu

引用次数: 0

A Bibliometric Analysis of the Top-Cited Articles on Diabetic Foot Ulcers. 糖尿病足溃疡的文献计量学分析。

IF 1.7 4区医学

International Journal of Lower Extremity Wounds Pub Date : 2023-09-01 DOI: 10.1177/15347346211034388

Jiaxing You, Chao Liu, Yixin Chen, Weifen Zhu, Hongye Li, Lin Li

{"title":"A Bibliometric Analysis of the Top-Cited Articles on Diabetic Foot Ulcers.","authors":"Jiaxing You, Chao Liu, Yixin Chen, Weifen Zhu, Hongye Li, Lin Li","doi":"10.1177/15347346211034388","DOIUrl":"https://doi.org/10.1177/15347346211034388","url":null,"abstract":"The aim of this study was to determine the top-cited articles in the field of diabetic foot ulcer (DFU) research. A cross-sectional bibliometric analysis was conducted in January 2021 by using Boolean search terms in the Scopus and the Web of Science databases. The 50 top-cited articles that met the inclusion criteria were ranked and evaluated for several characteristics, including year of publication, country of origin, authorship, publishing journal, topic categories, publishing type, and level of evidence. The median number of citations per article in the list was 442 (interquartile range [IQR], 320-520), with a median of 21.8 citations (IQR, 16.5-34.5) per year since publication. The publication years ranged from 1986 to 2017, with 1998 accounting for the greatest number of studies (n = 7). The citation classics were published in 20 journals and originated from institutions in 9 countries. The majority of the studies were clinical, of which expert opinion/review with Level V evidence and clinical studies with Levels I and II evidence comprised the greater proportion in the list. This study provides useful insights into the history and development of DFU research. The top-cited list may serve as a quick reference for education curriculums and clinical practice, in addition to providing a foundation for further studies on this topic.","PeriodicalId":49181,"journal":{"name":"International Journal of Lower Extremity Wounds","volume":"22 3","pages":"588-598"},"PeriodicalIF":1.7,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/15347346211034388","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10270039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Implication of Peripheral Neuropathy on Unplanned Readmissions in Patients Hospitalized for Complicated Diabetic Foot Disease. 周围神经病变对合并糖尿病足病住院患者意外再入院的影响。

IF 1.7 4区医学

International Journal of Lower Extremity Wounds Pub Date : 2023-08-31 DOI: 10.1177/15347346231197885

Erwin Yii, Amos Au, Justin Bradley, Alan Saunder, Roger Bell, Ming K Yii

{"title":"Implication of Peripheral Neuropathy on Unplanned Readmissions in Patients Hospitalized for Complicated Diabetic Foot Disease.","authors":"Erwin Yii, Amos Au, Justin Bradley, Alan Saunder, Roger Bell, Ming K Yii","doi":"10.1177/15347346231197885","DOIUrl":"https://doi.org/10.1177/15347346231197885","url":null,"abstract":"Introduction. Unplanned readmissions are common following discharge in patients after hospitalization for diabetic foot disease (DFD) complications. The aim of this study was to identify factors associated with readmissions in these high-risk patients, treated in a multidisciplinary setting and the implication of measures that could effectively reduce readmission rates. Methods. Patients presenting with DFDs admitted between 2015 and 2017 were studied retrospectively in a single-centre patient database. The demographics and clinical comorbidities were analyzed and comparison was made between 2 groups: patients readmitted within 30 days of discharge and those who did not require readmission. Multivariate analysis was performed to identify risk factors associated with readmissions. Results. In total, 340 patients were included. The unplanned readmission rate was 10.9%. More than half of readmissions (71%) were related to wound deterioration and infection. In the readmission group, the patients had lower body mass index, higher rate of osteomyelitis, lower rate of debridement, and evidence of peripheral vascular disease below the knee in the index admissions but these were not significant. In the multivariate analysis, peripheral neuropathy was the only significant risk associated with unplanned readmissions (odds ratio: 2.78, 95% confidence interval: 1.23-6.29, P = .014). Conclusion. This study demonstrates a significant association between peripheral neuropathy and unplanned readmissions. The implications of this nonmodifiable risk factor in reducing readmissions include all levels of patient care delivery such as adequate preparation for discharge and transition back into the community. Recognition and education in successful long-term offloading of insensate diabetic feet may help reduce rates of unplanned readmission.","PeriodicalId":49181,"journal":{"name":"International Journal of Lower Extremity Wounds","volume":" ","pages":"15347346231197885"},"PeriodicalIF":1.7,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10185756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk Factors for Ulcer Recurrence in Diabetic Patients Managed by an Integrated Foot Care Protocol. 综合足部护理方案管理糖尿病患者溃疡复发的危险因素。

IF 1.7 4区医学

International Journal of Lower Extremity Wounds Pub Date : 2023-08-31 DOI: 10.1177/15347346231191583

Laura Giurato, Panunzi Andrea, Marco Meloni, Chiara Pecchioli, Emanuela D'Ambrogi, Luigi Uccioli

{"title":"Risk Factors for Ulcer Recurrence in Diabetic Patients Managed by an Integrated Foot Care Protocol.","authors":"Laura Giurato, Panunzi Andrea, Marco Meloni, Chiara Pecchioli, Emanuela D'Ambrogi, Luigi Uccioli","doi":"10.1177/15347346231191583","DOIUrl":"https://doi.org/10.1177/15347346231191583","url":null,"abstract":"The aim of our study was to identify risk factors for the recurrence of diabetic foot ulcers (DFUs) in a selected population of patients in secondary prevention treated, according to International Guidelines, with an integrated foot care protocol by a referral diabetic foot clinic. A retrospective study was performed with the inclusion of selected outpatients with diabetes at higher risk for ulceration with a history of previous ulcer and/or amputation followed in our diabetic foot clinic between January 2015 and December 2021. According to the presence or absence of recurrence, patients were divided into 2 groups: ulcer recurrence and without ulcer recurrence. One hundred twenty-seven (127) patients were included, 47 patients (37%) developed an ulcer recurrence while 80 patients (63%) did not. The mean age was 71.7 years; 65% were male; 97% were affected by type 2 diabetes with a mean duration of 21.1 years, the mean HbA1c was 63 + 21 mmol/mol. Both groups of patients had foot deformities, such as claw and hammertoes; hallux valgus, and prominent metatarsal heads (MTHs). The presence of deformity was significantly associated with ulceration. The group with ulcer recurrence showed a higher rate of prominence MTHs in comparison to a group without ulcer recurrence. The MTHs resulted as the only independent predictor for recurrence. This study shows that the presence of the prominent MTH is a significant risk factor for ulcer recurrence in a selected population of diabetic foot patients treated in the best way with integrated foot care.","PeriodicalId":49181,"journal":{"name":"International Journal of Lower Extremity Wounds","volume":" ","pages":"15347346231191583"},"PeriodicalIF":1.7,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10129949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Elevator Speeches (Pitches) and the Pareto Principle. 电梯演讲(推销)和帕累托原则。

IF 1.7 4区医学

International Journal of Lower Extremity Wounds Pub Date : 2023-08-27 DOI: 10.1177/15347346231197499

Miltos K Lazarides, George S Georgiadis, Nikolaos Papanas

引用次数: 0

The Role of Escin as a Topical Agent for Lymphedema Treatment in a Rat Model. Escin作为局部药物治疗大鼠淋巴水肿模型的作用。

IF 1.7 4区医学

International Journal of Lower Extremity Wounds Pub Date : 2023-08-22 DOI: 10.1177/15347346231195944

Hyung Hwa Jeong, Donggeun Kim, Taehyun Kim, HyunSuk Peter Suh, ChangSik John Pak, Jae Yong Jeon, Joon Pio Hong

{"title":"The Role of Escin as a Topical Agent for Lymphedema Treatment in a Rat Model.","authors":"Hyung Hwa Jeong, Donggeun Kim, Taehyun Kim, HyunSuk Peter Suh, ChangSik John Pak, Jae Yong Jeon, Joon Pio Hong","doi":"10.1177/15347346231195944","DOIUrl":"https://doi.org/10.1177/15347346231195944","url":null,"abstract":"Escin, a naturally derived material isolated from horse chestnut, is used as an anti-inflammatory and anti-edema agent. This study aimed to evaluate its effects on lymphedema in a rat tail model. We divided the rats into five groups. The treatment groups received topical application of escin gel at concentrations of 20%, 10%, 2%, and 0.5% for 4 weeks. The fifth group served as a control. We performed volumetric (water displacement) tests, H&E staining, and LYVE-1 immunohistochemical staining, followed by statistical evaluation. All treatment groups showed significant volumetric reductions compared with the control group, but no significant differences were observed between the treatment groups. H&E staining showed a significant reduction in dermal thickness in the 20%, 10%, and 2% escin treatment groups compared to the control group. Within the treatment groups, the 2% escin group showed a significant difference compared with the 20% and 10% escin groups (p = 0.021 for both). LYVE-1 immunohistochemical staining revealed a significantly higher mean lymphatic vessel count in the 2% escin group compared with the 20%, 10%, and 0.5% escin-treated groups and the control group (p = 0.019, p = 0.025, p = 0.019, and p = 0.032 respectively). Topical escin applied to a rat tail model of acute lymphedema resulted in a significant reduction in tail volume, reduced dermal thickness, and increased lymphatic structures. The 2% escin concentration may be the optimal dose for improving lymphedema in this model. Further research is warranted to explore the clinical application of escin in patients with lymphedema.","PeriodicalId":49181,"journal":{"name":"International Journal of Lower Extremity Wounds","volume":" ","pages":"15347346231195944"},"PeriodicalIF":1.7,"publicationDate":"2023-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10047701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Usability of Different Methods to Assess and Improve Adherence to Therapeutic Footwear in Persons with the Diabetic Foot in Remission. A Systematic Review. 评估和改善糖尿病足缓解期患者治疗性鞋类依从性的不同方法的可用性。系统评价。

IF 1.7 4区医学

International Journal of Lower Extremity Wounds Pub Date : 2023-08-07 DOI: 10.1177/15347346231190680

Mateo López-Moral, Raúl J Molines-Barroso, María Herrera-Casamayor, Marta García-Madrid, Esther García-Morales, José Luis Lázaro-Martínez

{"title":"Usability of Different Methods to Assess and Improve Adherence to Therapeutic Footwear in Persons with the Diabetic Foot in Remission. A Systematic Review.","authors":"Mateo López-Moral, Raúl J Molines-Barroso, María Herrera-Casamayor, Marta García-Madrid, Esther García-Morales, José Luis Lázaro-Martínez","doi":"10.1177/15347346231190680","DOIUrl":"https://doi.org/10.1177/15347346231190680","url":null,"abstract":"Therapeutic footwear (TF) has been demonstrated to decrease the rate of recurrence in patients in remission. TF adherence determines the real effect of such treatment and, therefore, an appropriate evaluation of TF adherence is critical to decrease recurrence. The aim of this systematic review was to determine the usability of different methods of assessing adherence to TF in patients with diabetic foot ulcers under remission. The search strategy retrieved 506 articles. Title and abstract review excluded 472, while the full-text review excluded an additional 18 articles because the included data did not meet the selection criteria. Finally, we included 16 articles in this systematic review. Six (37.5%) of the 16 studies combined objective (OM) and subjective methods (SM). Only five (31.25%) evaluated OM and six (37.5%) studies only evaluated SM. Objective methods (temperature sensor, activity monitor) and subjective methods (survey, questionnaire) have successfully been used in the literature to evaluate TF adherence. Objective methods provided accurate data, whereas subjective methods led to response bias or missing data. Methods of evaluation showed that patients use the TF more frequently outdoors and on weekdays than indoors or on the weekend. In conclusion, objective methods are the most usable way to measure adherence to TF.","PeriodicalId":49181,"journal":{"name":"International Journal of Lower Extremity Wounds","volume":" ","pages":"15347346231190680"},"PeriodicalIF":1.7,"publicationDate":"2023-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10319305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Angiolymphoid Hyperplasia With Eosinophilia Associated With Stasis Dermatitis. 血管淋巴样增生伴嗜酸性粒细胞增多伴瘀血性皮炎。

IF 1.7 4区医学

International Journal of Lower Extremity Wounds Pub Date : 2023-08-07 DOI: 10.1177/15347346231194111

Si-Yu Luo, Li-Jia Deng, Sheng Fang

引用次数: 0