Interventional Neuroradiology最新文献

{"title":"Relationship between thrombus vWF and NETs with clinical severity and peripheral blood immunocytes' indicators in patients with acute ischemic stroke.","authors":"Shi Lin, Wei Chunxiao, Sun Li, Zhang Guimei, Zhang Yaru, Zhai Weijie, Qi Yiming, Zhou Ruolin, Meng Lingjie, Zhang Yan","doi":"10.1177/15910199241258374","DOIUrl":"10.1177/15910199241258374","url":null,"abstract":"<p><p>ObjectiveTo investigate the association between von Willebrand factor (vWF) and neutrophil extracellular traps (NETs) in thrombus with clinical severity and peripheral blood immunocytes' indicators in patients with early-stage acute ischemic stroke (AIS).MethodsA retrospective study was conducted using the clinical data of 66 patients with AIS who underwent endovascular mechanical thrombectomy and had their thrombus samples collected. The concentrations of vWF and NETs in the thrombus samples were quantitatively assessed. Peripheral blood samples taken in the early stages of the disease were analyzed for total white blood cell counts (WBC), ratios of neutrophils (NEU%), lymphocytes (LYM%), eosinophils (EOS%), and monocytes (MONO%). The severity of clinical symptoms in these patients was evaluated using the modified Rankin Scale (mRS), Essen Stroke Risk Score (ESRS), Barthel Index (BI), and National Institute of Health Stroke Scale (NIHSS).ResultsHigher vWF levels in thrombus were associated with lower NIHSS scores, while higher NETs levels were associated with higher initial NIHSS scores. In the early stages of AIS, WBC count and vWF levels were negatively correlated, as well as NEU%. LYM% was positively correlated with vWF level; however, it was negatively correlated with NETs. EOS% was positively correlated with vWF levels.ConclusionIn the early stages of AIS, a higher peripheral WBC count and NEU%, combined with decreased EOS% and LYM%, were significantly correlated with a lower vWF level in the thrombus, potentially indicating more severe symptoms. Consequently, the timely administration of vWF-targeted medications is recommended for such patients. Reduced LYM% is indicative of elevated NETs levels and correlated with more severe clinical symptoms. Therefore, the prompt initiation of NETs-targeted medication is warranted for these patients.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"1510-1517"},"PeriodicalIF":1.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11571128/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141161310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nationwide trends in intensive care unit utilization in the elective endovascular treatment of unruptured intracranial aneurysms.","authors":"Varun Padmanaban, William J Benjamin, Austin Cohrs, Francis J Jareczek, Sprague W Hazard, Joseph Christopher Zacko, Ephraim W Church, Scott D Simon, Kevin M Cockroft, Douglas L Leslie, David Andrew Wilkinson","doi":"10.1177/15910199241233028","DOIUrl":"10.1177/15910199241233028","url":null,"abstract":"<p><p>ObjectiveMultiple studies suggest routine post-operative intensive care unit (ICU) stays after endovascular treatment (EVT) of unruptured intracranial aneurysms (UIAs) is unnecessary, though rates of ICU utilization nationwide are unknown. We aim to evaluate rates and characteristics of ICU utilization in patients undergoing elective endovascular repair of UIAs.MethodsThis is a retrospective cohort study utilizing a nationwide private-payer database in the United States to evaluate the ICU utilization in patients undergoing elective endovascular repair of UIAs between 2005 and 2019. Demographics and pre-operative comorbidities as well as post-procedural complications and discharge status were compared. An analysis of charges and costs was also performed.ResultsAmong 6218 patients who underwent elective EVT of a UIA, 4890 (78.6%) were admitted to the ICU post-operatively. There were no differences in age, sex, or Charlson comorbidity scores in patients admitted to the ICU post-operatively compared to those admitted elsewhere. ICU utilization was more common in urban locations compared to rural. 12.7% of patients had ICU-specific needs sufficient to be billed by a critical care provider. Total provider costs were significantly higher in patients utilizing the ICU post-operatively, even among uncomplicated patients with routine discharges.ConclusionMost patients undergoing elective endovascular UIA repair in the United States are admitted to the ICU postoperatively. Only 12.7% have ICU needs, and these patients are predictable from pre-operative characteristics or peri-operative complications. Reducing ICU use in this subgroup of patients may be an important target to improve healthcare value in this patient population.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"1296-1302"},"PeriodicalIF":1.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569808/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140060964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A rare dissecting anterior inferior cerebellar artery aneurysm treated with flow diversion using a silk vista baby device.","authors":"Omar Kass-Hout, Ziad Darkhabani, Tibor Becske","doi":"10.1177/15910199241227467","DOIUrl":"10.1177/15910199241227467","url":null,"abstract":"<p><p>BackgroundDissecting intracranial pseudoaneurysms represent a challenge for treatment both endovascularly and surgically.MethodsWe review the treatment course of a ruptured anterior inferior cerebellar artery (AICA) dissecting pseudoaneurysm in a 50-year-old patient and review the history of dissecting aneurysms and AICA aneurysms treatment.ResultsAn aneurysm cure was achieved using flow diversion in the AICA. The recent introduction of flow diversion devices that can be deployed through 0.017\" microcatheters represents a new avenue for treatment of aneurysms.ConclusionTo the best of our knowledge this is the first published case of flow diversion in the(?) AICA to treat a dissecting aneurysm. The introduction of Silk Vista Baby and similar future devices is likely to widen the scope of aneurysm treatment utilizing flow diversion in distal distribution with small parent arteries.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"1966-1977"},"PeriodicalIF":1.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11577331/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139541312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endovascular biopsy in neurointerventional surgery: A systematic review.","authors":"Oleg Shekhtman, Georgios S Sioutas, Gennadii Piavchenko, Shubhang Bhalla, Daniel L Cooke, Ethan Winkler, Jan-Karl Burkhardt, Visish M Srinivasan","doi":"10.1177/15910199241240508","DOIUrl":"10.1177/15910199241240508","url":null,"abstract":"<p><p>IntroductionEndothelial cells (ECs) continuously line the cerebrovasculature. Molecular aberrations in the ECs are hallmarks and contributory factors to the development of cerebrovascular diseases, including intracranial aneurysms and arteriovenous malformations (AVMs). Endovascular biopsy has been introduced as a method to harvest ECs and obtain relevant biologic information. We aimed to summarize the literature on endovascular biopsy in neurointerventional surgery.MethodsWe conducted a comprehensive literature search in multiple databases, identifying eligible studies focusing on neurosurgical applications of endovascular biopsy. The systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. The relevant information was collected, including study characteristics, biopsy techniques, and key findings.ResultsNine studies met the inclusion criteria and were included. The studies involved the collection of ECs using various endovascular devices including coils, guide wires, different stents, and forceps. Endothelial-enrichment techniques, such fluorescence-activated cell sorting (FACS), collected ECs and facilitated downstream applications of bulk or single-cell RNA sequencing (scRNAseq). The studies provided insights into gene expression profiles and identified potential biomarkers associated with intracranial aneurysms. However, challenges were observed in obtaining an adequate number of ECs and identifying consistent biomarkers.ConclusionEndovascular biopsy of endothelial cells (ECs) in cerebrovascular pathologies shows promise for gene expression profiling. However, many studies have been limited in sample size and underpowered to identify \"signature genes\" for aneurysm growth or rupture. Advancements in minimally invasive biopsy methods have potential to facilitate applications of precision medicine in the treatment of cerebrovascular disorders.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"1637-1643"},"PeriodicalIF":1.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569772/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140186074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Embolization of a pseudoaneurysm of the innominate artery with a Woven EndoBridge (WEB) device.","authors":"Gil Zur, Areej Fageeh, Ange Diouf, Stacey Charette, Brigitte Charbonneau, Leila Sellami, Marlise Dos Santos, Howard Lesiuk, Brian Drake, Robert Fahed","doi":"10.1177/15910199241240504","DOIUrl":"10.1177/15910199241240504","url":null,"abstract":"<p><p>The Woven EndoBridge (WEB) is an intra-aneurysmal flow disruptor designed for the treatment of broad-based arterial aneurysms with a high safety and effectiveness profile.^{1, 2} It does not require concomitant antiplatelet therapy compared to other devices such as flow diverters or intracranial stents. Innominate artery pseudoaneurysms are a rare consequence of blunt traumatic injury, infection, or atherosclerotic disease.^{3, 4} We describe the case of an innominate artery pseudoaneurysm successfully treated with a WEB SL device instead of stenting, therefore alleviating the need for dual antiplatelet therapy. The treatment was successful and uneventful and postprocedural computed tomography angiography confirmed the complete occlusion of the pseudoaneurysm.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2069"},"PeriodicalIF":1.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11579839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140289330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metal allergy and neurovascular stenting: A systematic review.","authors":"Dhrumil Vaishnav, Muhammed Amir Essibayi, Aureliana Toma, Genesis Liriano, Raja Sandeep Perkash, Ariel Stock, Ryan Holland, Adam A Dmytriw, Stacey Q Wolfe, Sami Al Kasab, Alejandro Spiotta, Neil Haranhalli, David J Altschul","doi":"10.1177/15910199231226283","DOIUrl":"10.1177/15910199231226283","url":null,"abstract":"<p><p>BackgroundIntracranial stents and flow diverters contain significant amounts of metals, notably nickel, which can cause allergic reactions in a considerable portion of the population. These allergic responses may lead to complications like in-stent stenosis (ISS) and TIA/Stroke in patients receiving stents or flow diverters for intracranial aneurysms.MethodsWe conducted a systematic review of studies from inception until July 2023, which reported outcomes of patients with metal allergy undergoing neurovascular stenting. The skin patch test was used to group patients into those with positive, negative, or absent patch test results but with a known history of metal allergy.ResultsOur review included seven studies with a total of 39 patients. Among them, 87% had a history of metal allergy before treatment. Most aneurysms (89%) were in the anterior circulation and the rest (11%) were in the posterior circulation. Skin patch tests were performed in 59% of patients, with 24% showing positive results and 33% negative. Incidental ISS was observed in 18% of patients, and the rate of TIA/Stroke was reported in 21%. The pooled rates of ISS and TIA/Stroke were higher in the first group (43% and 38%) compared to the second (18% and 9%) and third groups (15% and 15%), but these differences were not statistically significant.ConclusionsThe current neurosurgical literature does not provide a conclusive association between metal allergy and increased complications among patients undergoing neurovascular stenting. Further studies are necessary to gain a more comprehensive understanding of this topic.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"1569-1575"},"PeriodicalIF":1.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569732/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139473016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance assessment of the Surpass Evolve flow diverter for the treatment of intracranial aneurysms: A systematic review and meta-analysis.","authors":"Aaron Rodriguez-Calienes, Juan Vivanco-Suarez, Nicole M Castillo-Huerta, David Espinoza-Martinez, Cristian Morán-Mariños, Ximena Espiritu-Vilcapoma, Valeria Rivera-Angles, Santiago Ortega-Gutierrez","doi":"10.1177/15910199241284412","DOIUrl":"10.1177/15910199241284412","url":null,"abstract":"<p><p>BackgroundThe Surpass Evolve (SE) has emerged as a promising alternative treatment from the flow diverter series. The utilization of the SE has gradually increased, however, there is a scarcity of comprehensive data on the solidity of this technology in the endovascular treatment of intracranial aneurysms (IAs). This meta-analysis aimed to evaluate the safety and effectiveness of the SE flow diverter.MethodsA systematic literature search from inception to April 2024 was conducted across five databases for studies involving IAs treated with the SE. The primary effectiveness outcome was the proportion of complete aneurysm occlusion at the final follow-up, and the primary safety outcome comprised a composite of early and delayed complications. Subgroup analyses based on aneurysm size, anatomical location, and rupture status were also conducted.ResultsOur analysis included nine studies with 645 patients and 722 IAs. Effectiveness outcomes revealed an overall complete aneurysm occlusion rate of 69% (95% confidence interval (CI) = 58%-78%; <i>I</i>²= 72%) and a favorable aneurysm occlusion rate of 91% (95% CI = 82%-96%; <i>I</i>²= 49%). Safety outcomes demonstrated an overall complications rate of 6% (95% CI = 3%-12%; <i>I</i>²= 66%), with an early complications rate of 6% (95% CI = 4%-11%; <i>I</i>²= 0%), and a delayed complications rate of 0% (95% CI = 0%-7%; <i>I</i>²= 0%).ConclusionsOur findings suggest a favorable outcome with a high rate of complete aneurysm occlusion at the last follow-up, with acceptable rates of neurological complications. Future research efforts should focus on larger, prospective studies with standardized outcome measures to further elucidate the clinical utility of the SE flow diverter in the management of IAs.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"1756-1764"},"PeriodicalIF":1.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559873/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of inferior alveolar artery and its variations using three-dimensional rotational angiography.","authors":"Emine Rana Sarıkaya, Elifhan Alagöz, Irfan Sarica, Temel Fatih Yılmaz","doi":"10.1177/15910199251380363","DOIUrl":"10.1177/15910199251380363","url":null,"abstract":"<p><p>PurposeThis study aims to evaluate the morphological features and branching patterns of the inferior alveolar artery (IAA) in living individuals using three-dimensional rotational angiography (3D-RA) and to propose a novel radiological classification based on its shape and branching pattern.MethodsA total of 101 hemifaces (53 right, 34 males/34 females) underwent 3D-RA imaging (slice thickness:0.10-0.20 mm). Morphological assessments of the maxillary artery (MA) and the IAA were performed on maximum intensity projection images. Statistical analysis used IBM SPSS Statistics 22.0 (<i>p</i> < 0.05).ResultsMean diameters of the internal carotid artery (ICA), external carotid artery (ECA), and MA were 4.62 ± 0.58 mm, 3.60 ± 0.87 mm, and 2.35 ± 0.41 mm, respectively. Females exhibited significantly smaller ICA, ECA, and MA diameters (<i>p</i> = 0.036, 0.001, 0.001), while IAA diameter (0.95 ± 0.19 mm) showed no sex difference. The IAA originated predominantly from the MA (96%), rarely from the ECA (4%), or was not observed (1%). Duplicated IAAs were detected in two cases. Branching patterns included a single vessel (71%) or a shared trunk with the posterior deep temporal artery (29%), showing significant correlation with MA course (superficial/deep) (<i>p</i> < 0.05). IAA shapes were categorized as straight, curved, or looped, addressing a literature gap.ConclusionsThis is the first in vivo study to radiologically classify variations of the IAA using 3D-RA. The technique enables high-resolution visualization of submillimeter vessels, offering valuable anatomical insights for maxillofacial surgeries. Further studies are warranted to validate these findings and explore clinical correlations.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"1552-1559"},"PeriodicalIF":1.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12460271/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Balloon-assisted U-turn Technique to Access Cortical Vein for Transvenous Embolization of Mixed Dural-pial Arteriovenous Malformation.","authors":"Muhammed Amir Essibayi, Dhrumil Vaishnav, Ryan Holland, David J Altschul","doi":"10.1177/15910199231226288","DOIUrl":"10.1177/15910199231226288","url":null,"abstract":"<p><p>Cerebral arteriovenous malformations can be classified into pure pial, mixed dural-pial, and pure dural types. Mixed pial-dural AVMs (DPAVM) are rare and often receive blood supply from dural meningeal arteries, including branches of the internal carotid, external carotid, and vertebral arteries.^{1- 6} DPAVMs, which are usually large and complex, require delicate endovascular and surgical treatment methods. The cure rate is low, and recurrence is very common, leading to high morbidity and mortality. In this case video, we present a case of PDAVM that recurred after initial endovascular onyx embolization, requiring additional endovascular coiling which resulted in obliteration of the DPAVM.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2070"},"PeriodicalIF":1.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11579843/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139473014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Monorail snare technique for retrieval of stretched coil.","authors":"Chiu-Shih Cheng, Wan-Ching Lin, Pei-Ling Lin, Cheng-Lung Lee, Chang-Hsien Ou","doi":"10.1177/15910199241239705","DOIUrl":"10.1177/15910199241239705","url":null,"abstract":"<p><p>Coil stretching is a recognized complication during cerebral aneurysm embolization.^{1, 3- 5} For over a decade, the microsnare has proven effective in retrieving migrated coils.^{1- 5} Fiorella et al. unveiled the \"Monorail Snare Technique\" in 2005, offering a specialized approach to stretched coil recovery.¹ However, to gain a complete understanding of this technique, more than just textual descriptions are necessary; a thorough, practical demonstration is essential. In our technical video (video 1), we illustrated an episode of coil stretching during aneurysm embolization, where the \"Monorail Snare Technique\" was successfully employed to retrieve a stretched coil. Our video emphasizes the meticulous preparation and modification of the microsnare, showcasing enhanced steps to mitigate the potential blood backflow triggered by the exclusive use of one-arm hemostasis valve during the \"Monorail Snare Technique.\"^{1, 5} This pivotal adjustment substantially lowers the threat of thromboembolic events. We highlighted essential precautions to ensure the procedure's safety and efficacy.^{4, 5}.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2067-2068"},"PeriodicalIF":1.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11573703/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140289331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}