Revista Internacional De Andrologia最新文献

{"title":"Evaluation of male sexual parameters in infertile couples with a history of abortion","authors":"Mehmet Caniklioglu ,&nbsp;Fatih Firat ,&nbsp;Ünal Oztekin ,&nbsp;Sercan Sari ,&nbsp;Volkan Selmi ,&nbsp;Levent Işikay","doi":"10.1016/j.androl.2021.02.001","DOIUrl":"10.1016/j.androl.2021.02.001","url":null,"abstract":"<div><h3>Introduction</h3><p>It is thought that both individuals are affected psychologically and sexually in couples experiencing abortion. In addition to the stress caused by infertility, sexual life may also be negatively affected in couples who experience psychogenic wear, such as abortion and curettage. The aim of this study is to evaluate male sexual functions in infertile couples with a history of abortion and male infertility component.</p></div><div><h3>Methods</h3><p>Five hundred forty-seven male patients’ data were evaluated retrospectively. Group 1 was the included the males of the couples without abortion history and the rest with abortion history was group 2. In addition to demographic data, abortion history, libido level, presence of morning erection and intercourse frequency were evaluated. Hormone levels of all patients were evaluated. After that we created sub-group 1 and sub-group 2 from these groups, respectively, due to whether the patients fulfilled the international index of erectile function (IIEF), Beck anxiety inventory (BAI) and Beck depression inventory (BDI).</p></div><div><h3>Results</h3><p>There were not any significant differences between the groups regarding psychiatric scale scores, hormone levels, libido, intercourse frequency and IIEF scores. Only orgasmic dysfunction was significant in the males of the couples with abortion history.</p></div><div><h3>Conclusion</h3><p>Man is not affected from abortion process in which woman get involved. Men only have orgasmic dysfunction when there is one or more abortion history in couples.</p></div>","PeriodicalId":49129,"journal":{"name":"Revista Internacional De Andrologia","volume":"20 ","pages":"Pages S48-S54"},"PeriodicalIF":0.8,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10344973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sugar-sweetened beverage intake in relation to reproductive parameters in young men","authors":"Jonathan Kiwitt-Cárdenas ,&nbsp;Julián J. Arense-Gonzalo ,&nbsp;Jaime Mendiola-Olivares ,&nbsp;Evdochia Adoamnei ,&nbsp;Alberto M. Torres-Cantero","doi":"10.1016/j.androl.2021.04.001","DOIUrl":"10.1016/j.androl.2021.04.001","url":null,"abstract":"<div><h3>Background</h3><p>There has been a decrease in sperm concentration in recent years. Concurrently, there were important dietary changes, including an increase in sugar-sweetened beverage intake (SSB). The relation between SSB and male reproduction functions in humans are barely described in the literature.</p></div><div><h3>Methods</h3><p>Cross-sectional study with 209 participants (18–23 years old) recruited during one year in Murcia, Spain. All men provided semen and blood samples the same day. SSB consumption was evaluated using a 101-item validated food frequency questionnaire. Reproductive hormones were analysed from serum samples, obtaining levels of follicle-stimulating hormone, inhibin B, luteinizing hormone, estradiol, and testosterone. The evaluation of semen analysis followed the WHO guidelines and consisted of seminal volume, sperm concentration, total sperm count, percentage of morphologically normal sperm, and percentage of motile sperm. SSB intake association with semen parameters and hormone levels were examined using multiple linear regression.</p></div><div><h3>Results</h3><p>Men in the highest quartile of the SSB intake had a higher percentage of morphologically normal sperm, 37.4% [6.1, 68.3] (<em>p</em>, trend<!--> <!-->=<!--> <!-->0.047) and higher estradiol levels (9.5% [−3.5, 22.5] (<em>p</em>, trend<!--> <!-->=<!--> <!-->0.047) than those in the first quartile. SSB intake was unrelated to other semen quality parameters or reproductive hormone levels.</p></div><div><h3>Conclusions</h3><p>Our results indicate that sperm morphology and estradiol levels may be associated with sugar-sweetened beverage intake. These findings might be explained by physiological metabolism homeostasis, though more studies are required to confirm these results and draw conclusions in other male populations.</p></div>","PeriodicalId":49129,"journal":{"name":"Revista Internacional De Andrologia","volume":"20 ","pages":"Pages S39-S47"},"PeriodicalIF":0.8,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10332458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can PCNA and LIM15 gene expression levels predict sperm retrieval success in men with non-obstructive azoospermia?","authors":"Muhammed Arif Ibis ,&nbsp;Kaan Aydos ,&nbsp;Volkan Baltaci ,&nbsp;Suleyman Aktuna ,&nbsp;Onder Yaman","doi":"10.1016/j.androl.2021.04.002","DOIUrl":"10.1016/j.androl.2021.04.002","url":null,"abstract":"<div><h3>Introduction and objectives</h3><p>It is necessary to be able to predict sperm retrieval before microdissection testicular sperm extraction (mTESE) in azoospermic men. This study established the importance of proliferating cell nuclear antigen (PCNA) and LIM15 gene expression levels in predicting the success of sperm retrieval by mTESE.</p></div><div><h3>Materials and methods</h3><p>One hundred and forty-three men who were diagnosed with non-obstructive azoospermia<span> (NOA) were included in the study. Patients’ age, total testosterone and follicle stimulating hormone values, testicular volume and testicular histology were recorded by prospectively. PCNA and LIM15 gene expression levels were determined by real-time PCR in the materials from both ejaculate and testicular specimens.</span></p></div><div><h3>Results</h3><p>Testis volume and histology were the most important factors in predicting the sperm retrieval rate (SRR). The PCNA and LIM15 gene expression levels measured in testicular tissues and the LIM15 gene expression levels measured in ejaculate significantly correlated with the SRR in mTESE (<em>p</em> <!-->=<!--> <!-->0.038, <em>p</em> <!-->=<!--> <!-->0.022, and <em>p</em> <!-->=<!--> <!-->0.004, respectively). Although the PCNA gene expression level measured in ejaculate was higher in men with successful sperm retrieval, the difference was not statistically significant (<em>p</em> <!-->=<!--> <!-->0.061). According to the multivariate logistic regression analysis, testicular volume and LIM15 gene expression level in ejaculate were independent predictive parameters for sperm retrieval.</p></div><div><h3>Conclusion</h3><p>The data showed that LIM15 gene expression level in ejaculate is a useful molecular marker to predict the SRR before mTESE.</p></div>","PeriodicalId":49129,"journal":{"name":"Revista Internacional De Andrologia","volume":"20 ","pages":"Pages S31-S38"},"PeriodicalIF":0.8,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10340777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MTHFR-c 677C>T polymorphism and male infertility: An analysis in a cohort of Pakistani men","authors":"Tasneem Fatima ,&nbsp;Usman Afzal ,&nbsp;Saeeda Shaharyar ,&nbsp;Shagufta Khan ,&nbsp;Mussarat Ashraf ,&nbsp;Wardah Rafaqat ,&nbsp;Muhammad Rohan Kayani ,&nbsp;Rehana Rehman","doi":"10.1016/j.androl.2021.05.001","DOIUrl":"10.1016/j.androl.2021.05.001","url":null,"abstract":"<div><h3>Objective</h3><p>To analyze existence of an association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism with male infertility.</p></div><div><h3>Materials and methods</h3><p>A case–control study was conducted from June 2017 to August 2018 in which 88 infertile and 40 fertile were recruited. Polymerase chain reaction (PCR) – restriction fragment length polymorphism (RFLP) assay was carried out to study the allelic frequency of C677T polymorphism. The differences in allelic and genotypic frequencies of C677T locus between fertile and infertile groups were evaluated by the Pearson chisquare test. A logistic regression model was used to calculate Odds ratios and 95% confidence intervals, <em>p</em> value<!--> <!-->&lt;<!--> <!-->0.05 was considered significant. The Hardy–Weinberg equilibrium was tested using HWE software.</p></div><div><h3>Results</h3><p><span>In infertile subjects, frequency distribution of CC allele was (60.2%), the CT allele was (30.7%) the TT allele was (9.1%) and in the fertile controls the frequency was CC allele (75%), CT allele (20%) and TT allele (5%) respectively. Analysis revealed MTHFR 677 CC genotype associated significantly with male infertility (</span><em>p</em> <!-->&lt;<!--> <!-->.046, OR<!--> <!-->=<!--> <!-->2.385; 95% CI<!--> <!-->=<!--> <!-->1.014–5.608); Frequency of CT (30.7%) and TT (9.1) genotypes were higher in infertile men as compared to CT (20%) TT (5%) in fertile controls but statistically these were not significantly different (<em>p</em> <!-->=<!--> <!-->0.097; OR<!--> <!-->=<!--> <!-->0.455; CI<!--> <!-->=<!--> <!-->0.179–1.153 and <em>p</em> <!-->=<!--> <!-->0.431; OR<!--> <!-->=<!--> <!-->0.526; CI<!--> <!-->=<!--> <!-->0.107–2.599 respectively). Significant association of age and BMI with MTHFR genotypes and infertility was observed.</p></div><div><h3>Conclusion</h3><p>Our results showed that MTHFR C677T polymorphism is not a risk factor for male infertility in our Pakistani population.</p></div>","PeriodicalId":49129,"journal":{"name":"Revista Internacional De Andrologia","volume":"20 4","pages":"Pages 274-280"},"PeriodicalIF":0.8,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40588226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Introducción","authors":"Esaú Fernández-Pascual,&nbsp;Juan Ignacio Martínez-Salamanca","doi":"10.1016/j.androl.2022.09.001","DOIUrl":"10.1016/j.androl.2022.09.001","url":null,"abstract":"","PeriodicalId":49129,"journal":{"name":"Revista Internacional De Andrologia","volume":"20 ","pages":"Page S1"},"PeriodicalIF":0.8,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33513009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Human kinematic and morphometric sperm subpopulation analysis using CASA technology: A new approach to spermatozoa classification","authors":"Almudena García-Molina ,&nbsp;Nuria Navarro ,&nbsp;Anthony Valverde ,&nbsp;Daznia Bompart ,&nbsp;Carina Caldeira ,&nbsp;Alberto Vendrell ,&nbsp;Carles Soler","doi":"10.1016/j.androl.2021.05.003","DOIUrl":"10.1016/j.androl.2021.05.003","url":null,"abstract":"<div><h3>Introduction</h3><p>Semen analysis is a clinical method aimed at determining the fertility of a male individual. The traditional subjective method lacks the reliability that can be achieved by computer-assisted sperm analysis (CASA) technology. Unfortunately, this technology has only been used when taking into consideration individually different sperm characteristics. The aim of this work is to present an integrative mathematical approach that considers different seminal variables to establish human sperm subpopulations.</p></div><div><h3>Methods</h3><p>Samples were obtained from thirteen volunteers via masturbation and were analyzed by the routine subjective method and two objective systems, CASA Motility (CASA-Mot) and CASA Morphology (CASA-Morph).</p></div><div><h3>Results</h3><p>Seminogram variables were reduced to three principal components (PC) showing two subpopulations. Kinematics and morphometric variables each rendered three PCs for four subpopulations.</p></div><div><h3>Conclusions</h3><p>These results lay the foundations for future studies including different geographical, social, ethnic and age range conditions with the aim of achieving a definitive view of the human semen picture.</p></div>","PeriodicalId":49129,"journal":{"name":"Revista Internacional De Andrologia","volume":"20 4","pages":"Pages 257-265"},"PeriodicalIF":0.8,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40592994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recuperación espermática post mortem: análisis técnico y legislativo en España a propósito de dos casos","authors":"Esther García Rojo ,&nbsp;Saturnino Lujan ,&nbsp;Manuel Alonso Isa ,&nbsp;Borja García Gómez ,&nbsp;José Medina Polo ,&nbsp;Javier Romero Otero","doi":"10.1016/j.androl.2021.02.002","DOIUrl":"10.1016/j.androl.2021.02.002","url":null,"abstract":"<div><h3>Introduction and objectives</h3><p>Advances in assisted reproductive techniques (ART) have caused an increase in requests for postmortem sperm retrieval (PMER). The use of these techniques is usually tied to legal, ethical and medical/casuistic problems. The objective of this work is to analyze technical and legal aspects of PMER in Spain using two real cases and to establish guidelines to help in decision-making after a PMER request.</p></div><div><h3>Material and methods</h3><p>Two real cases in which a PMER was requested and others published in Spain in recent years are presented. We proceed to an exposition of the techniques used in postmortem ART cases and specifically in PMER, and a detailed study of the current legal framework is carried out.</p></div><div><h3>Results</h3><p>In Spain we have a complete law on ART. Article 9 expressly requires an authorization from the deceased male partner for the use of his reproductive material in the following 12 months. Regarding the PMER, technical and logistical considerations require a quick and organized decision-making. The time until extraction should not exceed 24–36<!--> <!-->hours from death and a good choice of biological material is essential.</p></div><div><h3>Conclusions</h3><p>Medical-scientific advances now allow PMER and the use of postmortem ART. A good knowledge of the technical, logistical and legal aspects is necessary for a fast and coordinated action.</p></div>","PeriodicalId":49129,"journal":{"name":"Revista Internacional De Andrologia","volume":"20 ","pages":"Pages S61-S66"},"PeriodicalIF":0.8,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10340527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single nucleotide polymorphisms in 5-HT receptors in the etiology of premature ejaculation","authors":"Melis Danışman Sonkurt ,&nbsp;Gülcan Güleç ,&nbsp;Didem Turgut Coşan ,&nbsp;İbrahim Uğur Çalış ,&nbsp;Fezan Mutlu ,&nbsp;İyimser Üre ,&nbsp;Harun Olcay Sonkurt","doi":"10.1016/j.androl.2021.02.009","DOIUrl":"10.1016/j.androl.2021.02.009","url":null,"abstract":"<div><h3>Introduction and objectives</h3><p>Premature ejaculation (PE) is characterized by shorter intravaginal ejaculation latency time than it is acceptable for the patient or partner. It is thought that lifelong PE is a neurobiological dysfunction associated with genetic predisposition and with central serotonin neurotransmission dysfunction in receptors. To contribute to the understanding the genetic etiology of lifelong PE, it was planned to compare the 5-HT2C receptor gene rs3813929, rs518147, 5-HT1A receptor gene rs6295, 5-HT1B receptor gene rs11568817 of lifelong PE patients to healthy controls.</p></div><div><h3>Materials and methods</h3><p>For this purpose, 100 patients with premature ejaculation and 100 healthy controls were included in the study. Blood samples for DNA extraction were obtained. Appropriate procedures were applied to the probes (rs3813929, rs518147, rs6295, rs11568817) suitable for the DNA studied.</p></div><div><h3>Results</h3><p>A statistically significant relationship was found between the rs11568817 polymorphism (<em>p</em> <!-->=<!--> <!-->0.019) in the 5-HT1B receptor gene and the rs518147 polymorphism (<em>p</em> <!-->=<!--> <!-->0.016) in the 5-HT2C receptor gene. Also, no statistically significant relationship was found between 5-HT1A receptor gene rs6295 polymorphism and 5-HT2C receptor gene rs3813929 polymorphism and lifelong PE.</p></div><div><h3>Conclusions</h3><p>The relationship between rs3813929 and rs11568817 polymorphisms with lifelong PE was confirmed. Repeating the study in larger sample groups could be useful in determining the genetic etiology of PE.</p></div>","PeriodicalId":49129,"journal":{"name":"Revista Internacional De Andrologia","volume":"20 4","pages":"Pages 217-224"},"PeriodicalIF":0.8,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40561868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of triple vas deferens complaining of infertility: A challenging case report","authors":"Mohamed Yousry El-Amir,&nbsp;Sameh Fayek GamalEl Din","doi":"10.1016/j.androl.2021.04.004","DOIUrl":"10.1016/j.androl.2021.04.004","url":null,"abstract":"<div><p>There are multiple congenital structural abnormalities that affect male urogenital tract which could affect either the male external genitalia, internal genitalia or both. Congenital anomalies of the vas deferens may be unilateral or bilateral that could be complete or segmental and include (agenesis, atresia, duplication, ectopy or diverticulum). Anomalies of the vas deferens may be isolated or may be associated with other congenital anomalies especially in the male urogenital tract. These rare vas anomalies may be discovered during genital examination (either clinically or radiologically) or even accidentally during inguinal surgeries as in varicocelectomy, hernia repair, vasectomy or orchiopexy. We hereby reported the first case of triple vas deferens in a 35-year-old male that was felt on spermatic cord examination and confirmed by trans-rectal ultrasonography. Thus, proper evaluation should be made for the cases of multiple vas deferens to avoid the accidental injury during the operation and to exclude other associated congenital anomalies.</p></div>","PeriodicalId":49129,"journal":{"name":"Revista Internacional De Andrologia","volume":"20 4","pages":"Pages 281-284"},"PeriodicalIF":0.8,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40591016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corporoplasty under local anesthesia: Cost-effective improvement of the surgical treatment of Peyronie's disease","authors":"Morales Martínez Ana,&nbsp;Funes Padilla Carlos,&nbsp;Melgarejo Segura Mª Teresa,&nbsp;López Carmona Pintado Fernando,&nbsp;Arrabal Martín Miguel","doi":"10.1016/j.androl.2021.02.007","DOIUrl":"10.1016/j.androl.2021.02.007","url":null,"abstract":"<div><h3>Introduction and objectives</h3><p>Peyronie's disease produces penile curvature that leads, in certain cases, to difficulties in having satisfactory sexual relations.</p><p>The objective of this study is to evaluate the functional and cost-effectiveness results obtained in the surgical treatment of penile curvature due to Peyronie's disease under local anesthesia, comparing them with those performed under a general–spinal anesthesia regimen.</p></div><div><h3>Material and methods</h3><p>Two groups of patients undergoing corporoplasty are compared according to the type of anesthesia used. Group 1 consists of 32 patients who underwent major outpatient surgery and under local anesthesia from June 2016 to June 2019. Their data are collected prospectively. Group 2 consists of 30 patients who underwent surgery under general/spinal anesthesia with hospital admission, from January 2013 to December 2015, with their data collected retrospectively.</p><p>Anesthetic and surgical procedure, postoperative functional results, degree of satisfaction and hospital costs between both groups are analyzed, considering <em>p</em> <!-->≤<!--> <!-->0.05 as statistical significance and analyzing the results with the SPSS 20.0 program.</p></div><div><h3>Results</h3><p>Of the 32 patients included in group 1, none required admission for intra or postoperative complications. In both groups, an improvement of the PDQ-test was observed without statistically significant differences, with the degree of global satisfaction above 95% in both groups. There were also no differences in the appearance of complications secondary to the anesthetic procedure or the hospital regime. We observed differences in hospital costs, being 44% lower for the group performed with local anesthesia.</p></div><div><h3>Conclusions</h3><p>Surgical treatment of penile curvature under local anesthesia improves the cost-effectiveness ratio with the same quality of care, degree of satisfaction and postoperative functional results, maintaining a similar rate of intra/postoperative complications. For this reason, we consider that corporoplasty can be successfully performed under local anesthesia.</p></div>","PeriodicalId":49129,"journal":{"name":"Revista Internacional De Andrologia","volume":"20 4","pages":"Pages 231-236"},"PeriodicalIF":0.8,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40614052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}