{"title":"Comprehensive analysis of clinicopathologic and prognostic features in locally advanced thyroid papillary cancer","authors":"Liang Jiwang , Ye Dongman , Fang Fengqin , Zhao Yuejiao","doi":"10.1016/j.bjorl.2024.101553","DOIUrl":"10.1016/j.bjorl.2024.101553","url":null,"abstract":"<div><h3>Objective</h3><div>Differentiated thyroid cancers tend to excellent long-term survival after surgery. However, Locally Advanced Papillary Thyroid Cancers (LAPTCs) have poor prognosis. This study was to investigate the clinicopathologic features of LAPTC and the risk factors that affect its postoperative recurrence. We aimed to construct a nomogram to predict Recurrence-Free Survival (RFS) in LAPTC.</div></div><div><h3>Methods</h3><div>We retrospectively reviewed the data of patients who underwent surgery from 2011 to 2020 at a single institution. Univariate and multivariate analyses were used to investigate the clinicopathologic features of LAPTC. The risk factors that affecting recurrence of LAPTC were screened. The risk factors were subsequently integrated to establish a predictive model. C-index, receiver operating characteristic curve and calibration curve were used to validate the accuracy. A Decision Analysis Curve (DCA) was used to evaluate the clinical value.</div></div><div><h3>Results</h3><div>A total of 2530 Early Papillary Thyroid Cancer (EPTC) and 764 LAPTC were enrolled. Compared to EPTC, the proportion of male, bilaterality, multifocality, tumor size > 1 cm, ETE, central lymph node metastasis, and lateral lymph node metastasis was higher in LAPTC (all <em>p</em> < 0.05). Univariate and multivariate analyses found that age ≥ 55-years-old, male, and ETE were independent risk factors for the LAPTC patients’ RFS (all <em>p</em> < 0.05). C-index of the nomogram was 0.79. The AUC values of nomogram were 0.767 (95% CI 0.626‒0.909) and 0.798 (95% CI 0.669‒0.926) for 3- and 5-year RFS, respectively. The calibration curves of the nomogram showed good accuracy and consistency, and the DCA curves exhibited that the model had good clinical utility.</div></div><div><h3>Conclusion</h3><div>Male patients who with tumors tumor > 1 cm, bilaterality, multifocality, and ETE are more likely to become LAPTC. LAPTC patients with age ≥ 55-years-old, tumor size > 1 cm, and ETE are more likely to have postoperative recurrence. The model can help surgeons to predict 3- and 5-year RFS in LAPTC.</div></div><div><h3>Evidence level</h3><div>This article’s evidence level is four. Level 4 evidence, the case series, comes in the form of a group of patients subjected to surgical procedure. Authors may detect a statistically significant and clinically relevant outcome.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 2","pages":"Article 101553"},"PeriodicalIF":1.7,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753965/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142927892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The clinical characteristics and surgical strategy in infants with lingual thyroglossal duct cyst","authors":"Fenghua Qin, Yihua Ni, Wenxia Chen","doi":"10.1016/j.bjorl.2024.101536","DOIUrl":"10.1016/j.bjorl.2024.101536","url":null,"abstract":"<div><h3>Objectives</h3><div>Lingual Thyroglossal Duct Cysts (LTDCs) are a rare variant of thyroglossal duct Cyst (LDC). This study aimed to explore the efficacy of transoral excision of LTDC and evaluate the added benefit of concomitant management of laryngomalacia during the surgical intervention.</div></div><div><h3>Methods</h3><div>Infants with LTDCs were retrospectively collected from our department from January 2009 to January 2022. The baseline characteristics, clinical symptoms, the features of transnasal flexible fiberoptic laryngoscopy, CT and MRI, surgical treatments, and follow-up results were described and analyzed.</div></div><div><h3>Results</h3><div>50 babies with LTDCs were included. Five infants had urgent bedside cyst aspiration prior to surgery for respiratory distress. All patients underwent cyst resection. Concurrent LTDC and laryngomalacia were found in 10 patients on preoperative laryngoscopy. Due to breathing and swallowing issues, these infants underwent transoral cyst removal and supraglottoplasty in the same surgical setting. 3 large cyst cases, laryngomalacia were undetectable pre-cystectomy. When extubation failed after 1weeks, repeat laryngoscopy revealed severe laryngomalacia necessitating successful supraglottoplasty. All patients were discharged from the hospital once oral intake is safe and adequate.</div></div><div><h3>Conclusion</h3><div>Transoral surgery for LTDC is an effective and safe surgical treatment. Additionally, identifying and promptly addressing other laryngeal conditions, such as laryngomalacia, significantly enhances the success rate of the surgery.</div></div><div><h3>Level of evidence</h3><div>4.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 2","pages":"Article 101536"},"PeriodicalIF":1.7,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753967/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xuwei Duan , Jian Xu , Xueqin Liu , Duoping Wang , Biaoyou Chen
{"title":"A modified vertical pressure bandage to prevent pharyngocutaneous fistula after total laryngectomy","authors":"Xuwei Duan , Jian Xu , Xueqin Liu , Duoping Wang , Biaoyou Chen","doi":"10.1016/j.bjorl.2024.101537","DOIUrl":"10.1016/j.bjorl.2024.101537","url":null,"abstract":"<div><h3>Objective</h3><div>Pharyngocutaneous Fistula (PCF) is one of the most common and challenging postoperative complications after Total Laryngectomy (TLE). This study aimed to evaluate the impact of the modified Vertical Pressure Bandage (VPB) on the occurrence of Pharyngocutaneous Fistula (PCF) after Total Laryngectomy (TLE) for Head and Neck (H&N) cancer.</div></div><div><h3>Methods</h3><div>This retrospective study included patients with H&N cancer who underwent TLE at our hospital between January 2010 and January 2021. The patients were grouped according to whether modified VPB was used or not after surgery. The primary outcome was the occurrence of PCF. The secondary outcomes were the interval from operation to PCF, the healing time of PCF, and the length of hospital stay.</div></div><div><h3>Results</h3><div>This study included 133 patients: 82 (aged 57.93 ± 10.18 years, 80 males) in the VPB group and 51 (aged 54.98 ± 9.22 years, 51 males) in the conventional group. Patients who received the modified VPB had a significantly lower occurrence of PCF compared with those did not (9.8% vs. 33.3%, <em>p</em> = 0.001). In addition, the patients in the VPB group had similar interval from the operation to the PCF (<em>p</em> = 0.374) and healing time of PCF (<em>p</em> = 0.256) but a significantly shorter length of hospital stay (<em>p</em> < 0.001) compared with those in conventional group. Moreover, multivariable logistic regression analysis showed that, after adjusting for age, preoperative radiotherapy, postoperative hematocrit < 35%, VPB (RR = 0.165, 95% CI 0.057‒0.474, <em>p</em> = 0.001) was an independent protective factor for PCF.</div></div><div><h3>Conclusion</h3><div>The modified VPB might reduce the occurrence of PCF after TLE for H&N cancers.</div></div><div><h3>Level of evidence</h3><div>Level 4.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 2","pages":"Article 101537"},"PeriodicalIF":1.7,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753971/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142927888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Photobiomodulation in Brazil: Current scenario and evidence-based practice in the voice clinic","authors":"Gustavo Polacow Korn , Renata Rangel Azevedo , Viviane Souza Bicalho Bacelete, Claudia Alessandra Eckey","doi":"10.1016/j.bjorl.2024.101543","DOIUrl":"10.1016/j.bjorl.2024.101543","url":null,"abstract":"","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 1","pages":"Article 101543"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11699270/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142830606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative outcomes of video-assisted thyroidectomy and traditional open surgery: a 5-year analysis of a single center experience","authors":"Kenzo Ohara , Takumi Kumai , Kan Kishibe , Hidekiyo Yamaki, Hiroki Komatsuda , Tatsuya Hayashi, Miki Takahara","doi":"10.1016/j.bjorl.2024.101539","DOIUrl":"10.1016/j.bjorl.2024.101539","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to evaluate and compare the outcomes of patients undergoing video-assisted thyroidectomy versus those undergoing traditional open surgery.</div></div><div><h3>Methods</h3><div>In this retrospective study, we reviewed the clinical records of 449 patients who underwent thyroid surgery at our institution between April 2017 and March 2022. Of these, 209 underwent video-assisted thyroidectomy, while 248 underwent traditional open surgery. After excluding those who received total thyroidectomy, central node dissection, or lateral node dissection, we focused our analysis on 136 patients with video-assisted lobectomy and 92 patients with traditional open surgery. We compared patient outcomes, including surgical results and adverse events, between these groups.</div></div><div><h3>Results</h3><div>Significant differences were observed in the maximum tumor diameter between the video-assisted lobectomy and traditional open surgery groups. However, no significant differences were noted in surgical time, bleeding, or adverse events.</div></div><div><h3>Conclusion</h3><div>Video-Assisted Neck Surgery (VANS) offers great cosmetic benefits and is comparable to traditional open surgery in terms of adverse events.</div></div><div><h3>Level of evidence</h3><div>IV.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 2","pages":"Article 101539"},"PeriodicalIF":1.7,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698927/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fetih Furkan Şahin , İsa Kaya , Hakan Ceylan , Tayfun Kirazlı
{"title":"The modified asymmetric chondro-perichondrial island graft in type I tympanoplasty: A retrospective analysis of 784 patients","authors":"Fetih Furkan Şahin , İsa Kaya , Hakan Ceylan , Tayfun Kirazlı","doi":"10.1016/j.bjorl.2024.101540","DOIUrl":"10.1016/j.bjorl.2024.101540","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to assess the efficacy of a novel modified asymmetric chondro-perichondrial island graft in tympanoplasty. The design features a longer anterior segment compared to the posterior segment, addressing limitations of symmetrical grafts. We investigated the impact of this modified graft on hearing improvement and graft success rates in patients undergoing tympanoplasty surgery.</div></div><div><h3>Methods</h3><div>This retrospective study evaluated 784 patients with chronic otitis media who underwent primary type I tympanoplasty with a modified asymmetric chondro-perichondrial island graft technique. Demographics and characteristics of all patients, preoperative location of the perforation, and Pure-Tone Audiometry (PTA) were assessed preoperatively, and graft success and postoperative hearing outcomes were evaluated at the 12-month follow-up.</div></div><div><h3>Results</h3><div>This study evaluated the efficacy of a modified asymmetric chondro-perichondrial island graft in tympanoplasty. In 784 patients, the mean 12-month postoperative Air-Bone Gap (ABG) improvement was 17.3 dB with a 99% graft success rate. Preoperative ABG significantly improved from 24 dB to 6.6 dB postoperatively (<em>p</em> < 0.001). Perforation location did not affect ABG improvement (<em>p</em> = 0.193) but did influence graft success rate (<em>p</em> < 0.001). No sensorineural hearing loss, retraction pockets, or cholesteatoma were observed postoperatively.</div></div><div><h3>Conclusion</h3><div>Tympanoplasty offers a well-established surgical approach for restoring hearing function and preventing recurrent otorrhea. The asymmetric cartilage-perichondrium island graft design has emerged as a promising technique to achieve optimal functional and anatomical outcomes in tympanoplasty.</div></div><div><h3>Level of evidence</h3><div>Level 4.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 2","pages":"Article 101540"},"PeriodicalIF":1.7,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11699043/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wildna Sharon Martins da Costa , Lucas Barbosa de Araújo , Henrique de Paula Bedaque , Lidiane Maria de Brito Macedo Ferreira , Karyna Myrelly Oliveira Bezerra de Figueiredo Ribeiro
{"title":"Impact of the somatosensory influence on annoyance and quality of life of individuals with tinnitus: A cross-sectional study","authors":"Wildna Sharon Martins da Costa , Lucas Barbosa de Araújo , Henrique de Paula Bedaque , Lidiane Maria de Brito Macedo Ferreira , Karyna Myrelly Oliveira Bezerra de Figueiredo Ribeiro","doi":"10.1016/j.bjorl.2024.101542","DOIUrl":"10.1016/j.bjorl.2024.101542","url":null,"abstract":"<div><h3>Objective</h3><div>To assess the impact of the somatosensory influence on annoyance and quality of life of individuals with tinnitus.</div></div><div><h3>Methods</h3><div>This cross-sectional study included individuals with tinnitus of both sexes, aged ≥18 years, recruited from a specialized otolaryngology outpatient, and evaluated by a multidisciplinary team (otorhinolaryngologists, physical therapists, and audiologists). An evaluation adapted from the Diagnostic Criteria of Somatosensory Tinnitus (ST) was performed to verify the influence of the somatosensory system on the cause of tinnitus. The intensity of discomfort from tinnitus was assessed by the Numerical Rating Scale, the impact on quality of life by the Tinnitus Handicap Inventory (THI), and factors of exacerbation of tinnitus were self-reported. Individuals were divided into ST and non-ST groups. Unpaired <em>t</em>-test and Chi-Square were used for group comparisons; Cohen's <em>d</em> and Phi measured effect sizes.</div></div><div><h3>Results</h3><div>A total of 100 individuals were evaluated: 46 from the ST group and 54 from the non-ST group. The ST group demonstrated greater discomfort from tinnitus (<em>p</em> < 0.01); stress was identified as a factor of exacerbation 82.6 (<em>p</em> < 0.01), and sleep disturbance as a consequence of tinnitus 63% (<em>p</em> = 0.04). Additionally, the ST group presented a greater impact on quality of life in the functional domain (<em>p</em> = 0.03) and total THI score (<em>p</em> = 0.05) than the non-ST group.</div></div><div><h3>Conclusion</h3><div>Individuals with ST reported greater discomfort from tinnitus and a more significant impact on the quality of life.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 2","pages":"Article 101542"},"PeriodicalIF":1.7,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11699070/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jérôme R. Lechien , Luigi A. Vaira , Bianca M. Georgescu , Antonino Maniaci , Stéphane Hans , Sven Saussez
{"title":"Recovery of misattributed congenital anosmia after platelet-rich plasma injections: Report of two cases","authors":"Jérôme R. Lechien , Luigi A. Vaira , Bianca M. Georgescu , Antonino Maniaci , Stéphane Hans , Sven Saussez","doi":"10.1016/j.bjorl.2024.101538","DOIUrl":"10.1016/j.bjorl.2024.101538","url":null,"abstract":"","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 2","pages":"Article 101538"},"PeriodicalIF":1.7,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ling Tian , Min Zhao , Qing Yang , Xiaojiang Li , Yun Chen , Xifang Wu , Yan-Xin Ren
{"title":"Impact of smoking and alcohol drinking on the prognosis of 721 nasopharyngeal carcinoma","authors":"Ling Tian , Min Zhao , Qing Yang , Xiaojiang Li , Yun Chen , Xifang Wu , Yan-Xin Ren","doi":"10.1016/j.bjorl.2024.101534","DOIUrl":"10.1016/j.bjorl.2024.101534","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to examine the correlation between smoking, alcohol drinking, and the prognosis of Nasopharyngeal Carcinoma (NPC).</div></div><div><h3>Methods</h3><div>Clinical data from 721 NPC cases treated at our hospital between January 2005 and December 2010 were collected. Information on smoking and drinking, including duration, daily quantity, and cumulative amount, was recorded and graded according to WHO standards. Statistical analysis was performed to assess the influence of smoking and alcohol drinking on NPC patient prognosis. After controlling for confounding factors, survival analysis compared the 5-year Progression-Free Survival rate (PFS) and Overall Survival rate (OS) among patients with varying degrees of smoking and drinking. The association between smoking, drinking, cumulative amount, and NPC patient prognosis was evaluated. Multivariate Cox regression analysis was then employed, considering patient demographic characteristics and clinical features, to comprehensively analyze prognostic influencing factors in NPC patients. Additionally, the multivariate Cox regression analysis was utilized to comprehensively examine the influencing factors of prognosis, taking into account the patients' basic demographic characteristics and clinical features. The findings revealed significant differences in the aforementioned rates.</div></div><div><h3>Results</h3><div>(1) Analysis of PFS and OS differences in NPC patients considered smoking status, smoking duration, daily smoking quantity, and cumulative smoking amount. No significant influence of smoking on NPC patient PFS and OS within 5-years was observed (<em>p</em> > 0.05). (2) Non-drinkers with NPC exhibited higher 5-year PFS and OS rates compared to drinkers (<em>p</em> = 0.047, <em>p</em> = 0.026). Furthermore, non-drinkers and those with a drinking duration of less than 120 months or between 120–240 months showed higher 5-year PFS and OS rates than individuals with a drinking duration exceeding 240 months (<em>p</em> < 0.05). Similarly, non-drinkers and individuals consuming less than 50 g/day had higher 5-year PFS and OS rates compared to those consuming 50–100 g/day or more than 100 g/day (<em>p</em> < 0.05). Additionally, the 5-year PFS and OS rates were higher in the non-drinking and light drinking groups compared to the moderate and heavy drinking groups (<em>p</em> < 0.05). (3) A partial synergistic effect between smoking and alcohol drinking was observed in NPC. (4) Alcohol drinking emerged as an independent prognostic factor for NPC.</div></div><div><h3>Conclusion</h3><div>Alcohol drinking is a significant factor influencing the prognosis of nasopharyngeal carcinoma, with the adverse effects further amplified when combined with smoking.</div></div><div><h3>Level of evidence</h3><div>Level 2.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 2","pages":"Article 101534"},"PeriodicalIF":1.7,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Caroline da Silva Seidler, Marianne Yumi Nakai, Lucas Ribeiro Tenório, Daniela Serrano Marquezin, Renata Santos Bittencourt Silva, Marcelo Benedito Menezes, Antonio José Gonçalves
{"title":"Rehabilitation after supracricoid partial laryngectomy: cohort study","authors":"Caroline da Silva Seidler, Marianne Yumi Nakai, Lucas Ribeiro Tenório, Daniela Serrano Marquezin, Renata Santos Bittencourt Silva, Marcelo Benedito Menezes, Antonio José Gonçalves","doi":"10.1016/j.bjorl.2024.101532","DOIUrl":"10.1016/j.bjorl.2024.101532","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate vocal, swallowing and respiratory rehabilitation of patients undergoing supracricoid laryngectomy; evaluate the impact of voice changes and global quality of life.</div></div><div><h3>Methods</h3><div>It is a prospective cohort study where voice, swallowing and respiratory rehabilitation where evaluated. Quality of life was assessed using EORTC QLQ-C30 and H&N35 questionnaires.</div></div><div><h3>Results</h3><div>31 patients were included in the study. 70.4% of patients were T3. In swallowing assessment, two patients (6.4%) were considered non-rehabilitated. Ten patients (32.2%) were considered partially rehabilitated and 19 (61.3%) fully rehabilitated. Sensitivity was abnormal at 74.2%. Penetration occurred in 58.1% of patients with 29% experiencing aspiration. In voice assessment, 19 (61.3%) patients were considered rehabilitated. 77.41% had a calculated voice handicap index considered abnormal. When assessing breathing, eight patients (25.8%) were considered non-rehabilitated. Disease-free survival was 87.1% in follow-up of 5.77 years. When subjected to specific exams and evaluations, only 38.7% were completely rehabilitated. When comparing results of EORTC-C30 and H&N35 questionnaires with the reference values, global score and domain scores are better on the patients of the study, as well as some of the symptoms.</div></div><div><h3>Conclusion</h3><div>Partial supracricoid laryngectomy remains an option in patients with laryngeal tumors, especially in the most advanced ones, with a survival rate around 90%. Quality of life is impacted after surgery, but with few symptoms.</div></div><div><h3>Level of evidence</h3><div>Level 3.<span><span><sup>1</sup></span></span></div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 2","pages":"Article 101532"},"PeriodicalIF":1.7,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}