Contact Lens & Anterior Eye最新文献

{"title":"Diversity and composition of ocular microbiota in contact lens wearers: Efficacy of liposomal ozonated oil.","authors":"María Carmen Sánchez-González, Inmaculada Gallardo-Real, Estanislao Gutiérrez-Sánchez, Concepción De-Hita-Cantalejo, Raúl Capote-Puente, José-María Sánchez-González","doi":"10.1016/j.clae.2025.102368","DOIUrl":"https://doi.org/10.1016/j.clae.2025.102368","url":null,"abstract":"<p><strong>Purpose: </strong>To characterize the ocular surface microbiota in regular contact lens wearers with dry eyes and assess the effectiveness of reducing bacterial load using a liposomal ozonated oil solution.</p><p><strong>Methods: </strong>This prospective, longitudinal, controlled study randomized subjects into two groups. Group A (45 subjects) received hydroxypropylmethylcellulose (HPMC, Artific®), while Group B (41 subjects) received ozonated sunflower seed oil with soybean phospholipids (OSSO, Ozonest®). Microbial communities were analyzed via DNA metabarcoding of the 16S rRNA gene, and statistical analyses (alpha and beta diversity) were performed in R.</p><p><strong>Results: </strong>Both groups predominantly harbored Staphylococcus caprae, Streptococcus oralis, and Corynebacterium spp., with OSSO and HPMC users showing distinct bacterial profiles. Alpha diversity showed no significant differences, but beta diversity revealed differences in bacterial composition between the groups.</p><p><strong>Conclusions: </strong>The results seem to indicate that the use of ozonized oil reduces the bacterial load compared to the solution used as a control.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102368"},"PeriodicalIF":4.1,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142957574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corneal astigmatism after temporary discontinuation from long-term spherical and toric orthokeratology.","authors":"Bi Yang, Longqian Liu, Pauline Cho","doi":"10.1016/j.clae.2024.102365","DOIUrl":"https://doi.org/10.1016/j.clae.2024.102365","url":null,"abstract":"<p><strong>Objective: </strong>To investigate changes in corneal astigmatism (curvatures and corneal sagittal height difference (C-sagDiff) at 8-mm chord) after temporary discontinuation from long-term spherical and toric orthokeratology (ortho-k) lens wear in a Chinese population.</p><p><strong>Methods: </strong>Relevant data were retrieved from 110 patients (55 wearing spherical ortho-k lenses, 55 wearing toric ortho-k lenses) who have been undergoing ortho-k treatment for at least one year and stopped lens wear temporarily for scheduled lens replacement. The topographic and refraction data at baseline and post-discontinuation was collected for all the patients. Only data from the right eye was used for analysis. Corneal curvature changes and C-sagDiff at 8-mm chord in the two principal meridians within each group and the corneal astigmatism changes between the two groups were analyzed.</p><p><strong>Results: </strong>No significant differences in age, gender, baseline flat K (FK) and steep K (SK), myopia, refractive astigmatism, and duration of lens wear were noted between the two groups (P > 0.05). Baseline corneal astigmatism and C-sagDiff in toric ortho-k group was higher than spherical ortho-k group (P < 0.001). For both ortho-k groups, after treatment discontinuation of about 1-month (30-37 days), FK became flatter, SK remained unchanged, corneal astigmatism and C-sagDiff increased. Changes in corneal astigmatism for spherical and toric groups were 0.24 ± 0.33 and 0.32 ± 0.32 D, respectively. C-sagDiff increased from 22.85 ± 8.41 to 31.37 ± 12.98 μm and from 32.35 ± 12.39 to 45.40 ± 15.01 μm in the spherical and toric ortho-k groups, respectively. No significant between-group difference in corneal astigmatism change was found (P = 0.214). Corneal astigmatism change was affected by wearers' age and duration of ortho-k lens wear. The younger the subject and the longer the duration of ortho-k lens wear, the more significant the corneal astigmatism change after discontinuation of the treatment.</p><p><strong>Conclusion: </strong>After 1-month discontinuation from long-term ortho-k lens wear, corneal flat K became flatter, steep K remained unchanged, the C-sagDiff and the corneal astigmatism increased, irrespective of whether spherical or toric lenses were used. The change of corneal astigmatism was about 0.25D on average, which was not clinically significant. There was no significant difference of corneal and refractive astigmatism change between spherical and toric ortho-k groups.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102365"},"PeriodicalIF":4.1,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of transient receptor potential channel modulators for dry eye: A systematic review and meta-analysis.","authors":"Xiaohong Duan, Mohan Ju, Xinquan Liu, Jindong Hu","doi":"10.1016/j.clae.2024.102347","DOIUrl":"https://doi.org/10.1016/j.clae.2024.102347","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the efficacy and safety of transient receptor potential (TRP) channel modulators for dry eye.</p><p><strong>Methods: </strong>A thorough search for randomized clinical trials was conducted in seven databases up to February 16, 2024. Suitable studies were identified according to inclusion and exclusion criteria, extracted data were synthesized and analyzed using Review Manager 5.4, and risk of bias and quality of evidence were assessed using recommended tools.</p><p><strong>Results: </strong>Six trials with 884 patients using two kinds of TRP channel modulators (TRPV1 antagonist and TRPM8 agonist) were included. TRP channel modulators were effective in reducing subjective symptom scores (standardized mean differences [SMD], -0.41; 95 % confidence interval [CI], -0.75 to -0.07), corneal fluorescence staining (mean differences [MD], -0.19; 95 % CI, -0.37 to -0.02), impact on quality of life and daily function, and increasing the non-anesthetic Schirmer's test score (MD, 11.71; 95 % CI, 9.59 to 13.83), instant tear meniscus height (MD, 245.52; 95 % CI, 14.02 to 477.02), improvement in conjunctival hyperemia (risk ratio [RR], 2.08; 95 % CI, 1.07 to 4.06). There was no increased incidence of adverse events with TRP modulators compared to vehicle solution controls.</p><p><strong>Conclusions: </strong>TRP channel modulators have shown positive therapeutic effects in reducing the symptoms and signs of dry eye and improving the quality of life associated with the disease without raising the risk of adverse events. These modulators are expected to become a new therapy for dry eye.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102347"},"PeriodicalIF":4.1,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142927395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Celebrating 30 years of an ongoing annual international contact lens prescribing survey (1996-2025).","authors":"Philip B Morgan, Nathan Efron","doi":"10.1016/j.clae.2024.102355","DOIUrl":"https://doi.org/10.1016/j.clae.2024.102355","url":null,"abstract":"","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102355"},"PeriodicalIF":4.1,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142899630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Topical Ivermectin-metronidazole gel therapy improves Meibomian gland Function in blepharitis caused by demodex spp.","authors":"Marcel Y Ávila, Felipe Andrés Quesada, Edgar M Espana","doi":"10.1016/j.clae.2024.102354","DOIUrl":"https://doi.org/10.1016/j.clae.2024.102354","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the efficacy and safety of topical Ivermectin- Metronidazol in the management of demodex infestation and their effect in Meibomian gland dysfunction (MGD) METHODS: Fifty-four patients (108 eyes) with demodex diagnosis and Meibomian gland dysfunction received Ivermectin 0.3 %+Metronidazole 0.5 % gel in the night for 5 weeks. Parameters were evaluated before and 8 weeks after the last application of IVM-MTZ. This includes demodex counts, OSDI tests, non-invasive breakup time (NIBUT), average noninvasive breakup time (AvNIBUT), and infrared meibography with the determination of glandular dropout.</p><p><strong>Results: </strong>A complete eradication of infestation was observed with the proposed treatment. A significant improvement in NIBUT, AvNIBUT, and OSDI score. The Meibomian gland improved with the treatment with a reduction of the glandular dropout from 50 ± 1.4 % to 39.05 ± 1.2 % (P < 0.0005) CONCLUSIONS: Management of demodex infestation in MGD improves tear film parameters, reduces ocular symptoms, and induces improvement in the anatomy of Meibomian glands. This is the first intervention that induces anatomical changes in Meibomian glands and must be considered as a modality for the treatment of MGD-demodex coexistence.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102354"},"PeriodicalIF":4.1,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation and repeatability assessment of the Chinese version of the Ocular Surface Disease Index (OSDI), 5-item dry eye (DEQ-5), and contact lens dry eye questionnaire-8 (CLDEQ-8) questionnaires.","authors":"Biyue Guo, K Y Chan, Peter H Li, Jimmy S H Tse, Xulin Liao, Dylan Eng, Connie Chen, Ziqi Meng, Ruihua Wei, Allen Cheong, William Ngo, Thomas C Lam","doi":"10.1016/j.clae.2024.102353","DOIUrl":"https://doi.org/10.1016/j.clae.2024.102353","url":null,"abstract":"<p><strong>Purpose: </strong>This prospective study aimed to validate the translated Chinese versions of the Ocular Surface Disease Index (OSDI), 5-Item Dry Eye (DEQ-5), and Contact Lens Dry Eye Questionnaire-8 (CLDEQ-8) questionnaires and test their repeatability.</p><p><strong>Methods: </strong>From August 2022 to July 2023, online (qualtrics.com) English and Chinese versions of OSDI, DEQ-5, and CLDEQ-8 questionnaires were distributed to residents of Hong Kong, mainland China, Taiwan, and Singapore ≥ 18 years old who could understand both written Chinese and English. Subjects who were regular contact lens wearers (wear contact lenses > 5 days/week and > 8 h/day) were invited to complete the English and Chinese versions of the CLDEQ-8 questionnaire. Those who were not regular contact lens wearers were requested to complete the English and Chinese OSDI and DEQ-5 questionnaires. Subjects who completed the questionnaires were invited to participate for the second time three days later. Cronbach's alpha coefficient and intraclass correlation coefficient were used to test the internal consistency test-retest reliability of the translated questionnaires, respectively.</p><p><strong>Results: </strong>A total of 141 subjects completed the OSDI and DEQ-5 (50 (35 %) completed the second attempt) and 96 completed the CLDEQ-8 questionnaires (52 (54 %) completed the second time). All Chinese versions of the questionnaires showed adequate internal consistency (Cronbach's alpha coefficient ≥ 0.872) and high reliability. There were no significant differences between the two attempts for Chinese OSDI and DEQ-5, but a statistically (not clinically) significant difference for the Chinese CLDEQ-8. This indicates that the Chinese version is clinically comparable to the English version.</p><p><strong>Conclusion: </strong>The Chinese versions of OSDI, DEQ-5, and CLDEQ-8 questionnaires showed adequate internal consistency and high reliability. Despite not being identical in measured scores, the translated Chinese questionnaires could effectively provide information about dry eye conditions and be used as alternative tools for assessing and diagnosing dry eye in clinical practice.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102353"},"PeriodicalIF":4.1,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial intelligence-assisted fitting method using corneal topography outcomes enhances success rate in orthokeratology lens fitting.","authors":"Xueyi Zhou, Li Zeng, Yang Shen, Zhe Zhang, Chongyang Wang, Bingjie Wang, Pauline Kang, Xingtao Zhou, Zhi Chen","doi":"10.1016/j.clae.2024.102350","DOIUrl":"https://doi.org/10.1016/j.clae.2024.102350","url":null,"abstract":"<p><strong>Purpose: </strong>Based on ideal outcomes of corneal topography following orthokeratology (OK), an innovative machine learning algorithm for corneal refractive therapy (CRT) was developed to investigate the precision of artificial intelligence (AI)-assisted OK lens fitting.</p><p><strong>Methods: </strong>A total of 797 eyes that had been fitted with CRT lenses and demonstrated good lens centration with plus power ring intact in their topography were retrospectively included. A comprehensive AI model included spherical refraction, keratometry readings, eccentricity, corneal astigmatism, horizontal visible iris diameter, inferior-superior index, surface asymmetry index, surface regularity index and 8-mm chordal corneal height difference. A simplified AI model omitted the latter four parameters. Correlation and disparity in predicted lens parameters between the AI prediction and manufacturer's conventional lens fitting method were compared.</p><p><strong>Results: </strong>There was overall no significant difference between AI predicted parameters and the final ordered parameters (p > 0.05). The horizontal return zone depth (RZD1, p = 0.022) and vertical return zone depth (RZD2, p < 0.001) values suggested by the conventional method were significantly lower, while the horizontal landing zone angle (LZA1) was significantly larger (p = 0.002) than those of the final ordered lens. The AI predicted parameters were significantly correlated to those of the final ordered lens (p < 0.01), with the correlation coefficients of base curve radius (BCR), RZD1, RZD2, LZA1, vertical LZA (LZA2) and total lens diameter (TD) being 0.958, 0.708, 0.773, 0.697, 0.654 and 0.730, respectively, for the comprehensive AI model. The correlation coefficients were higher in RZD2, LZA1 and TD with the AI model as compared to conventional method.</p><p><strong>Conclusions: </strong>Compared with the conventional method, AI predicted lens parameters exhibit less disparity and improved accuracy, with a potential to facilitate more efficient and precise CRT OK lens fitting.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102350"},"PeriodicalIF":4.1,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Randomised controlled trial on effects of topical insulin compared to artificial tears and normal saline on tear inflammatory mediator levels and clinical parameters in diabetics with dry eye disease.","authors":"A Atikah, M Suzana, W A H Wan Haslina, M D Norshamsiah, M Mushawiahti, K S S Birinder, S F Tang, M L C Bastion","doi":"10.1016/j.clae.2024.102346","DOIUrl":"https://doi.org/10.1016/j.clae.2024.102346","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the short-term effects of topical insulin (TI) as compared to topical Systane Ultra^TM (Alcon, USA) as artificial tears (AT) and topical normal saline (NS) on tear inflammatory mediators; interleukin 1-alpha (IL-1a), interleukin 6 (IL-6) and matrix metalloproteinase 9 (MMP-9) and clinical dry eye parameters in diabetics with dry eye disease (DDED).</p><p><strong>Methods: </strong>In this randomized, multi-arm parallel single-centre trial, 73 diabetics with dry eye disease (30 female and 43 male) aged 18 to 50 years were recruited. They were randomly assigned to four weeks of treatment of either TI 0.5 unit/drop, AT or NS four times per day. Tear sample analysis and clinical parameters of dry eye (Ocular Surface Disease Index (OSDI), tear break-up time (TBUT), corneal Oxford score and Schirmers test) were evaluated at baseline and four weeks later. Objective clinical parameters for corneal Oxford score and tear break-up time were assessed by two masked investigators.</p><p><strong>Results: </strong>Significant reduction was seen in all inflammatory biomarkers (IL-1a, IL-6 and MMP-9) in all treatment groups at 4 weeks. In addition, inflammatory biomarkers demonstrated a significant reduction with TI (p < 0.001). Meanwhile, in AT and NS groups, reduction was also significant but less than TI group. Similarly, significant improvements were seen in all clinical parameters evaluated with all 3 treatments at 4 weeks; with TI group showing largest improvement as compared to AT and NS groups (p < 0.001). This is supported with the results as follows: mean difference -20.90 for OSDI as compared to -11.38 and -6.78 for AT and NS groups, respectively, 5.55 s for TBUT as compared to 3.00 s and 1.00 s for AT and NS group respectively, -2.40 for Oxford score as compared to -0.38 and -1.39 for AT and NS group respectively, and 5.20 mm for Schirmers test as compared to 3.00 mm and 1.00 mm for AT and NS group respectively.</p><p><strong>Conclusion: </strong>Treatment with TI resulted in the greatest reduction in inflammatory biomarkers and ocular eye parameters, as compared to AT and NS. TI was most effective in improving clinical parameters of DDED, although all topical therapies showed significant improvements, suggesting that use of TI may be beneficial in treating DDED.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102346"},"PeriodicalIF":4.1,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142830603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and evaluation of ocular antibiotic-loaded soluble film inserts.","authors":"Alfredo Desiato, Affiong Iyire, Gurpreet Bhogal-Bhamra, Shehzad A Naroo, Raquel Gil-Cazorla","doi":"10.1016/j.clae.2024.102352","DOIUrl":"https://doi.org/10.1016/j.clae.2024.102352","url":null,"abstract":"<p><p>Antibiotic eyedrops typically require frequent instillation due to the eye's defensive mechanisms limiting drugs from reaching target sites. This may risk patient non-adherence and treatment inefficacy. The aim of this study was to develop a biocompatible and fully soluble ocular film insert to enhance the delivery of levofloxacin, as well as the handling procedure for its administration; based on the anatomical dimensions and physiological conditions of the human eye. Inserts were prepared by solvent casting method, using HPMC, sodium alginate, gelatin, PEG 400, and levofloxacin solution, and characterised for various physicochemical properties (e.g., uniformity of weight and thickness, loss on dryness, swelling index, water uptake and surface pH). Mechanical properties were assessed and compared against a commercially available buccal film formulation. Uniformity of content and release profile of inserts were assessed by means of a validated analytical method. Antibacterial effectiveness was studied by adapted disc diffusion method on Staphylococcus aureus and Pseudomonas aeruginosa. The formulation including HPMC E15 (1250 mg), low viscosity sodium alginate (750 mg), type A gelatin (250 mg) and PEG 400 (2.5 mL) and 0.1% levofloxacin solution, resulted in high quality inserts, exhibiting uniformity of mass, thickness, and levofloxacin content, that comply with Pharmacopeial standards. Inserts were able to withstand unilinear and repeated mechanical stresses, suggesting suitability for manipulation linked to eye administration. The fully soluble levofloxacin-loaded inserts exhibited good physicochemical and mechanical characteristics, indicating good compatibility with ocular environment and administration procedure. Consistent levofloxacin content and biphasic release pattern showed immediate and sustained antimicrobial efficacy, consistently above the minimum inhibitory concentrations for the model species tested. This work also presents an experimental framework that can be adapted for designing and testing ocular drug delivery systems accounting for anatomical and physiological characteristics of the eye.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102352"},"PeriodicalIF":4.1,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital eye strain and clinical correlates in older adults.","authors":"Patrick A Moore, James S Wolffsohn, Amy L Sheppard","doi":"10.1016/j.clae.2024.102349","DOIUrl":"https://doi.org/10.1016/j.clae.2024.102349","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the screen time habits, associated symptoms and clinical characteristics of an older population (60 years and older) drawn from primary care optometry.</p><p><strong>Methods: </strong>Consecutive patients aged 60 years and older, who used a digital device for at least 1 hour per day, attending for an eye examination at a primary care optometric practice in Dublin, Ireland, were invited to participate. The study gathered information regarding the participant's use of digital devices, the types of devices used and duration of use. Best corrected distance acuity and near vision adequacy for reading and device use was recorded.</p><p><strong>Results: </strong>401 responses were included in the analysis. Based on a Computer Vision Syndrome Questionnaire (CVS-Q) score ≥6, the occurrence of DES in this population was high at 51.6 % with females having a higher median score than males. The mean number of hours devices were used for was 4 hours. 71 % of participants reported symptoms of digital eye strain (DES) when using digital devices. Smart phones were the device type used most by participants but tablets were the device type used for the longest duration. Single vision spectacles were the most commonly used method of visual correction when using digital devices. Participants with better levels of acuity used devices for longer periods than those with poorer acuity.</p><p><strong>Conclusion: </strong>This study provides a valuable insight into the screen habits and likelihood of symptoms of DES in an older population and, is to date, the first of its kind. It shows that the prevalence of DES in older age adult device users is high, at 51.6 %, with a clear link between dry eye and symptoms of DES. Its results will enable optometrists to provide specific advice to this age group on how best to reduce symptoms of DES.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102349"},"PeriodicalIF":4.1,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}