International Journal of Environmental Research and Public Health最新文献

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The Global COVID-19 Pandemic Experience: Innovation Through Environmental Assessment and Seropositivity Surveillance. 全球COVID-19大流行经验:通过环境评估和血清阳性监测进行创新。
3区 综合性期刊
International Journal of Environmental Research and Public Health Pub Date : 2025-07-18 DOI: 10.3390/ijerph22071145
Robert M Park
{"title":"The Global COVID-19 Pandemic Experience: Innovation Through Environmental Assessment and Seropositivity Surveillance.","authors":"Robert M Park","doi":"10.3390/ijerph22071145","DOIUrl":"10.3390/ijerph22071145","url":null,"abstract":"<p><strong>Objectives: </strong>To confirm a conjecture from year 2020 of the SARS-CoV-2 (COVID-19) pandemic suggesting policy alternatives to substantially reduce mortality burden.</p><p><strong>Methods: </strong>Data from a global COVID-19 database comparing different countries on cumulative mortality and vaccination were analyzed in conjunction with surveys of seropositivity. Predictions of final mortality burden under an alternate policy scenario for Japan were calculated and the COVID-19 outcomes for China were assessed.</p><p><strong>Results: </strong>By 2025, Western countries (US, UK, Brazil and Italy) had cumulative mortality rates in the range of 3339-3548 deaths per million, about 6-fold higher than East Asian and New Zealand 'zero-COVID' countries. Moderate virus suppression in Japan produced the lowest cumulative mortality of the countries analyzed; if earlier policies had been maintained, the predicted cumulative mortality rate by 2025 would be one-tenth that of the US, UK, Brazil and Italy and one-half to one-third that of other zero-COVID countries. For China, transitioning from a zero-COVID policy in 2022-2023, the estimated 2025 cumulative mortality was 1607/million, half that of Western countries.</p><p><strong>Conclusions: </strong>To minimize COVID-19 mortality would require: (1) Innovation on systematic sampling of ambient airborne virus exposure to sustain low but non-zero virus levels across entire populations, and (2) seropositivity assessment (instead of mass PCR testing for new cases) for calibrating exposure management, and tracking and protecting high-risk populations.</p>","PeriodicalId":49056,"journal":{"name":"International Journal of Environmental Research and Public Health","volume":"22 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12294177/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: Martin et al. The Health Literacy of First Year Physiotherapy and Speech Pathology Students and Their Perceived Future Roles in Supporting Their Clients' Health Literacy. Int. J. Environ. Res. Public Health 2023, 20, 6013. 更正:Martin等人。物理治疗和语言病理学一年级学生的健康素养及其在支持客户健康素养方面的作用。Int。j .包围。Res.公共卫生2023,20,6013。
3区 综合性期刊
International Journal of Environmental Research and Public Health Pub Date : 2025-07-18 DOI: 10.3390/ijerph22071134
Romany Martin, Jade Cartwright, Marie-Louise Bird
{"title":"Correction: Martin et al. The Health Literacy of First Year Physiotherapy and Speech Pathology Students and Their Perceived Future Roles in Supporting Their Clients' Health Literacy. <i>Int. J. Environ. Res. Public Health</i> 2023, <i>20</i>, 6013.","authors":"Romany Martin, Jade Cartwright, Marie-Louise Bird","doi":"10.3390/ijerph22071134","DOIUrl":"10.3390/ijerph22071134","url":null,"abstract":"<p><p>The authors have requested that the following changes be made to the original publication [...].</p>","PeriodicalId":49056,"journal":{"name":"International Journal of Environmental Research and Public Health","volume":"22 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12295365/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diminished Social and Leisure Engagement in Community Dwelling-Older Adults with Apathy. 社区居住中社会和休闲参与减少——冷漠的老年人。
3区 综合性期刊
International Journal of Environmental Research and Public Health Pub Date : 2025-07-18 DOI: 10.3390/ijerph22071138
Katherine J Valles, Emmeline Ayers, Joe Verghese, Mirnova E Ceïde
{"title":"Diminished Social and Leisure Engagement in Community Dwelling-Older Adults with Apathy.","authors":"Katherine J Valles, Emmeline Ayers, Joe Verghese, Mirnova E Ceïde","doi":"10.3390/ijerph22071138","DOIUrl":"10.3390/ijerph22071138","url":null,"abstract":"<p><strong>Background: </strong>Apathy predicts functional and cognitive decline in community-dwelling older adults. However, the behavioral correlates of apathy, which could promote cognitive decline have not been described. Our objective was to investigate the associations of apathy with leisure and social engagement.</p><p><strong>Methods: </strong><i>N</i> = 538 older adults enrolled in the Central Control of Mobility in Aging study. We used the GDS3A, a 3-item subscale of the Geriatric Depression Scale, to define apathy and the frequency of participation in cognitive, physical, and social leisure activities. Linear regression models were conducted to assess the association between apathy and its behavioral correlates: social engagement and leisure activity participation. Covariates included age, gender, education level, multimorbidity, and dysphoria.</p><p><strong>Results: </strong>Apathy was present in 29.7% of participants and was significantly associated with less frequent participation in physical activity days per week (-1.688. <i>p</i> = 0.003) but not cognitive (-1.094, <i>p</i> = 0.252) or social (-0.654, <i>p</i> = 0.103) leisure activities. Apathy was also associated with a decreased social behavior composite score (-0.055, <i>p</i> < 0.001), Social Network Index (-0.478, <i>p</i> = 0.003), and Medical Outcomes Study Social Support scores (-0.26, <i>p</i> = 0.001).</p><p><strong>Conclusions: </strong>Our findings suggest that apathy presents with reduced participation in physical leisure activities and reduced social engagement, which may provide a way for clinicians and caregivers to identify apathy in the future.</p>","PeriodicalId":49056,"journal":{"name":"International Journal of Environmental Research and Public Health","volume":"22 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12294408/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adapting a Participatory Group Programme for Caregivers of Children with Complex Neurodisability from Low-, Middle-Income Countries to a High-Income Setting: Moving from "Baby Ubuntu" to "Encompass". 将低收入和中等收入国家复杂神经残疾儿童护理人员的参与性小组方案调整到高收入环境:从“婴儿Ubuntu”到“包含”。
3区 综合性期刊
International Journal of Environmental Research and Public Health Pub Date : 2025-07-18 DOI: 10.3390/ijerph22071144
Kirsten Prest, Kirsten Barnicot, Catherine Hurt, Frances Badenhorst, Aleksandra Borek, Melanie Whyte, Phillip Harniess, Alea Jannath, Rachel Lassman, Christopher Morris, Rachel Osbourne, Tracey Smythe, Cally J Tann, Keely Thomas, Emma Wilson, Angela Harden, Michelle Heys
{"title":"Adapting a Participatory Group Programme for Caregivers of Children with Complex Neurodisability from Low-, Middle-Income Countries to a High-Income Setting: Moving from \"Baby Ubuntu\" to \"Encompass\".","authors":"Kirsten Prest, Kirsten Barnicot, Catherine Hurt, Frances Badenhorst, Aleksandra Borek, Melanie Whyte, Phillip Harniess, Alea Jannath, Rachel Lassman, Christopher Morris, Rachel Osbourne, Tracey Smythe, Cally J Tann, Keely Thomas, Emma Wilson, Angela Harden, Michelle Heys","doi":"10.3390/ijerph22071144","DOIUrl":"10.3390/ijerph22071144","url":null,"abstract":"<p><p>The \"Baby Ubuntu\" programme is a well-established, low-cost, community-based intervention to support caregivers of children with complex neurodisability, like cerebral palsy, in low- and middle-income country (LMIC) contexts. This process-focused paper describes our utilisation of the ADAPT guidance to adapt \"Baby Ubuntu\" for use in ethnically and linguistically diverse, and economically deprived urban boroughs in the United Kingdom (UK). The process was guided by an adaptation team, including parents with lived experience, who explored the rationale for the intervention from local perspectives and its fit for this UK community. Through qualitative interviews and co-creation strategies, the perspectives of caregivers and healthcare professionals substantially contributed to the \"Encompass\" programme theory, drafting the content, and planning the delivery. Ten modules were co-produced with various topics, based on the \"Baby Ubuntu\" modules, to be co-facilitated by a parent with lived experience and a healthcare professional. The programme is participatory, allowing caregivers to share information, problem solve, and form supportive peer networks. The \"Encompass\" programme is an example of a \"decolonised healthcare innovation\", as it aims to transfer knowledge and solutions developed in low- and middle-income countries to a high-income context like the UK. Piloting of the new programme is underway.</p>","PeriodicalId":49056,"journal":{"name":"International Journal of Environmental Research and Public Health","volume":"22 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12295255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association Between Diet, Sociodemographic Factors, and Body Composition in Students of a Public University in Ecuador. 厄瓜多尔一所公立大学学生饮食、社会人口因素和身体组成的关系
3区 综合性期刊
International Journal of Environmental Research and Public Health Pub Date : 2025-07-18 DOI: 10.3390/ijerph22071140
Angélica María Solís Manzano, María Victoria Padilla Samaniego, Verónica Patricia Sandoval Tamayo, Edgar Rolando Morales Caluña, Katherine Denisse Suarez Gonzalez, Tannia Valeria Carpio-Arias, Patricio Ramos-Padilla
{"title":"Association Between Diet, Sociodemographic Factors, and Body Composition in Students of a Public University in Ecuador.","authors":"Angélica María Solís Manzano, María Victoria Padilla Samaniego, Verónica Patricia Sandoval Tamayo, Edgar Rolando Morales Caluña, Katherine Denisse Suarez Gonzalez, Tannia Valeria Carpio-Arias, Patricio Ramos-Padilla","doi":"10.3390/ijerph22071140","DOIUrl":"10.3390/ijerph22071140","url":null,"abstract":"<p><p>Body composition is associated with multiple factors. The main objective of this study is to determine the association between diet and sociodemographic factors on the body structure and composition of university students at a public university in Ecuador. This cross-sectional study allowed for the collection of detailed body composition and dietary data from 204 students (41.7% men and 58.3% women, with an average age of 23.3 ± 4.4 years). The study was conducted using validated questionnaires and bioimpedance techniques. Statistical analysis included ANOVA tests, complemented by a PCA-Biplot, to examine the relationships between study variables. Statistical analysis revealed that men's birthplace had a significant impact on several body measurements, such as hip circumference and weight, but no significant differences were observed in body structure and composition based on nutrient intake. Furthermore, larger upper-arm circumference in women was correlated with higher fat intake. The results of the multivariate analysis indicated a differential influence of dietary components on body composition. The study highlights the need for nutritional intervention strategies and educational programs that consider the diversity of students' backgrounds to promote healthy habits and mitigate the negative effects of eating habits and irregular physical activity patterns on their health and body composition.</p>","PeriodicalId":49056,"journal":{"name":"International Journal of Environmental Research and Public Health","volume":"22 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12295282/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Breast Cancer Survivors' Perception on Health Promotion and Healthy Lifestyle: A Systematic Review and Qualitative Meta-Synthesis. 乳腺癌幸存者对健康促进和健康生活方式的认知:系统回顾和定性综合。
3区 综合性期刊
International Journal of Environmental Research and Public Health Pub Date : 2025-07-17 DOI: 10.3390/ijerph22071131
Luca Guardamagna, Orejeta Diamanti, Giovanna Artioli, Lorenzo Casole, Matteo Bernardi, Francesca Bonadies, Enrico Zennaro, Gloria Maria Modena, Tiziana Nania, Federica Dellafiore
{"title":"Breast Cancer Survivors' Perception on Health Promotion and Healthy Lifestyle: A Systematic Review and Qualitative Meta-Synthesis.","authors":"Luca Guardamagna, Orejeta Diamanti, Giovanna Artioli, Lorenzo Casole, Matteo Bernardi, Francesca Bonadies, Enrico Zennaro, Gloria Maria Modena, Tiziana Nania, Federica Dellafiore","doi":"10.3390/ijerph22071131","DOIUrl":"10.3390/ijerph22071131","url":null,"abstract":"<p><p><b>Aims:</b> To systematically review and synthesize qualitative research exploring the Breast Cancer Survivors (BCSs)' perception of health promotion interventions and informing strategies to mitigate recurrence risk within five years post-treatment and improve clinical outcomes. Specifically, this study addresses the question: \"How do women diagnosed with breast cancer perceive health promotion interventions for recurrence prevention?\" <b>Design</b>: A systematic review and qualitative meta-synthesis were performed. <b>Data Sources</b>: A systematic search of scientific databases (CINAHL, MEDLINE, and Scopus) was undertaken in November 2024. The reference list was cross-referenced and hand-searched to identify additional articles. <b>Review Methods</b>: Studies were included if they met the following criteria: they were primary qualitative studies focusing on BCSs within five years post-treatment, involving participants who had completed surgery, radiotherapy, or chemotherapy in the same time frame, as this period is critical for monitoring recurrence and implementing health promotion interventions. Only studies published in peer-reviewed journals and written in Italian, English, French, or Spanish were considered, provided that an abstract and the full text were available. Moreover, eligible studies had to be conducted in high-income or middle-income countries. Studies were excluded if they focused exclusively on advanced or metastatic breast cancer, if they involved mixed cancer populations without reporting separate data for BCSs, or if they were non-qualitative studies or gray literature. The review study protocol was registered in the PROSPERO database (CRD42024626033). <b>Results</b>: The literature search identified 490 records, 13 articles from databases, and 3 articles identified via other methods (web and citation searching) that met inclusion criteria. A narrative synthesis approach allowed the emerging five themes: (I) <i>Challenges</i>, (II) <i>Self-motivation and empowerment</i>, (III) <i>The relationships as a facilitator</i>, (IV) <i>Barriers to change</i>, and (V) <i>Proactive support strategies</i>. <b>Conclusions</b>: Addressing internal and external factors that influence health behaviors is essential to improve adherence, reduce recurrence risk, and enhance quality of life. Tailored interventions, social support, and healthcare engagement are crucial in this effort. <b>Impact</b>: Our meta-synthesis highlighted significant challenges as well as valuable resources for health promotion among BCSs, suggesting practical and tailored approaches to improving the adoption of healthy behaviors, supported by relationships and targeted support strategies.</p>","PeriodicalId":49056,"journal":{"name":"International Journal of Environmental Research and Public Health","volume":"22 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12294282/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implementation of Behavior Change Theories and Techniques for Physical Activity Just-in-Time Adaptive Interventions: A Scoping Review. 行为改变理论和技术在体育活动即时适应性干预中的应用:范围综述。
3区 综合性期刊
International Journal of Environmental Research and Public Health Pub Date : 2025-07-17 DOI: 10.3390/ijerph22071133
Parker Cotie, Amanda Willms, Sam Liu
{"title":"Implementation of Behavior Change Theories and Techniques for Physical Activity Just-in-Time Adaptive Interventions: A Scoping Review.","authors":"Parker Cotie, Amanda Willms, Sam Liu","doi":"10.3390/ijerph22071133","DOIUrl":"10.3390/ijerph22071133","url":null,"abstract":"<p><p>(1) Background: Physical activity (PA) is a key modifiable risk factor for chronic diseases, yet many adults do not meet PA guidelines. Just-in-time adaptive interventions (JITAIs), a type of mobile health (mHealth) intervention, offer tailored support based on an individual's context to promote PA. Integrating behavior change techniques (BCTs) and theories is critical to the design of effective mHealth interventions. Understanding which BCTs and theories work best can inform future JITAI development. (2) Objective: The objective of this study is to examine how behavior change theories and BCTs are implemented in mHealth PA JITAIs and assess their relationship with PA-related outcomes. (3) Methods: This scoping review followed the PRISMA-ScR guidelines. A total of 29 studies were included. (4) Results: The most commonly used BCTs include prompts/cues (<i>n</i> = 29), goal-setting (behavior) (<i>n</i> = 15), and feedback on behavior (<i>n</i> = 14), while self-determination theory (<i>n</i> = 4) and social cognitive theory (<i>n</i> = 4) are the most commonly used theories. However, there is insufficient evidence as to which theories and BCTs are most effective in eliciting effective PA behavior change. (5) Conclusions: Clearer reporting and integration of BCTs and behavior change theories, along with optimized user interfaces, are needed to improve the intervention quality, replicability, and long-term effectiveness of PA JITAIs.</p>","PeriodicalId":49056,"journal":{"name":"International Journal of Environmental Research and Public Health","volume":"22 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12295828/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Global Research Trends on Water Contamination by Microorganisms: A Bibliometric Analysis. 全球微生物水污染研究趋势:文献计量学分析。
3区 综合性期刊
International Journal of Environmental Research and Public Health Pub Date : 2025-07-17 DOI: 10.3390/ijerph22071128
Zoila Isabel Cárdenas Tirado, Isaías Wilmer Duenas Sayaverde, Rosario Del Socorro Avellaneda Yajahuanca, Sdenka Caballero Aparicio, Kelly Myriam Jiménez de Aliaga, Edo Gallegos Aparicio, Maria Antonieta Rubio Tyrrel, Maria do Livramento Fortes Figueiredo, José Wicto Pereira Borges, Rosilane de Lima Brito Magalhães, Denise Andrade, Daniela Reis Joaquim de Freitas, Ana Raquel Batista de Carvalho, Maria Eliete Batista Moura
{"title":"Global Research Trends on Water Contamination by Microorganisms: A Bibliometric Analysis.","authors":"Zoila Isabel Cárdenas Tirado, Isaías Wilmer Duenas Sayaverde, Rosario Del Socorro Avellaneda Yajahuanca, Sdenka Caballero Aparicio, Kelly Myriam Jiménez de Aliaga, Edo Gallegos Aparicio, Maria Antonieta Rubio Tyrrel, Maria do Livramento Fortes Figueiredo, José Wicto Pereira Borges, Rosilane de Lima Brito Magalhães, Denise Andrade, Daniela Reis Joaquim de Freitas, Ana Raquel Batista de Carvalho, Maria Eliete Batista Moura","doi":"10.3390/ijerph22071128","DOIUrl":"10.3390/ijerph22071128","url":null,"abstract":"<p><p>Water is an essential resource for life; however, the quality of available water on the planet has been compromised due to various factors, including microbiological contamination.</p><p><strong>Objective: </strong>To analyze the global scientific production of microbiological water contamination using bibliometric methods.</p><p><strong>Method: </strong>A search for scientific articles was conducted using the advanced query function in the Web of Science™ database, specifically in its core collection, on 26 February 2025. Data from 2000 articles were analyzed using the Bibliometrix package in R (version 4.2.1) and the Biblioshiny application (version 2.0).</p><p><strong>Results: </strong>The evaluated articles were published between 1952 and 2025, with a peak in publications in 2022. The journal <i>Water Research</i> stood out as the most relevant, publishing 128 articles. The Egyptian Knowledge Bank was identified as the most productive institution, while China had the highest number of contributing authors. The most cited article received 475 citations. Additionally, KeyWords Plus™ highlighted the focus of the studies on ecological and biotechnological methods for contaminant removal, as well as the presence of waterborne pathogens and their inactivation methods.</p><p><strong>Conclusions: </strong>The results show a growing interest in the development of ecological and biotechnological methods for contaminant removal and pathogen inactivation in water. The integration of artificial intelligence with real-time monitoring systems emerges as a promising strategy for improving water quality management. These findings highlight the relevance of the topic for public health and health education.</p>","PeriodicalId":49056,"journal":{"name":"International Journal of Environmental Research and Public Health","volume":"22 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12295613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Tandem MS Platform for Simultaneous Determination of Urinary Malondialdehyde and Diphenyl Phosphate. 同时测定尿丙二醛和磷酸二苯酯的串联质谱平台。
3区 综合性期刊
International Journal of Environmental Research and Public Health Pub Date : 2025-07-17 DOI: 10.3390/ijerph22071130
Gabriela Chango, Diego García-Gómez, Carmelo García Pinto, Encarnación Rodríguez-Gonzalo, José Luis Pérez Pavón
{"title":"A Tandem MS Platform for Simultaneous Determination of Urinary Malondialdehyde and Diphenyl Phosphate.","authors":"Gabriela Chango, Diego García-Gómez, Carmelo García Pinto, Encarnación Rodríguez-Gonzalo, José Luis Pérez Pavón","doi":"10.3390/ijerph22071130","DOIUrl":"10.3390/ijerph22071130","url":null,"abstract":"<p><p>This study presents an advanced analytical method for the simultaneous quantification of malondialdehyde (MDA), a biomarker of oxidative stress, and diphenyl phosphate (DPhP), a metabolite of the organophosphate flame retardant triphenyl phosphate (TPhP), in human urine. The method integrates hydrophilic interaction liquid chromatography (HILIC), a type of liquid chromatography suitable for polar compounds, for MDA separation, and an online restricted access material (RAM), a preconcentration column, for DPhP isolation, achieving high specificity and sensitivity. Validation with certified urine samples confirmed its robustness across diverse analyte concentrations and complex biological matrices. The optimized clean-up steps effectively minimized carryover, allowing for high-throughput analysis. Application to 72 urine samples revealed a significant positive correlation (ρ = 0.702, <i>p</i>-value = 1.9 × 10<sup>-7</sup>) between MDA and DPhP levels, supporting a potential link between oxidative stress and TPhP exposure. The subset analysis demonstrated a statistically significant moderate positive correlation in women (ρ = 0.622, <i>p</i>-value = 0.020), although this result should be interpreted with caution because of the limited sample size (N = 14). This method provides a powerful tool for biomonitoring oxidative stress and environmental contaminants, offering valuable insights into exposure-related health risks.</p>","PeriodicalId":49056,"journal":{"name":"International Journal of Environmental Research and Public Health","volume":"22 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12295514/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Exploratory Retrospective Analysis of Racial Disparities in Fall-Related Injuries Among Black and White Breast Cancer Survivors Receiving Chemotherapy. 接受化疗的黑人和白人乳腺癌幸存者中跌倒相关损伤的种族差异的探索性回顾性分析。
3区 综合性期刊
International Journal of Environmental Research and Public Health Pub Date : 2025-07-17 DOI: 10.3390/ijerph22071129
Asmaa Namoos, Dina Ramadan, Rashema Meekins, Vanessa Sheppard, Nicholas Thomson
{"title":"An Exploratory Retrospective Analysis of Racial Disparities in Fall-Related Injuries Among Black and White Breast Cancer Survivors Receiving Chemotherapy.","authors":"Asmaa Namoos, Dina Ramadan, Rashema Meekins, Vanessa Sheppard, Nicholas Thomson","doi":"10.3390/ijerph22071129","DOIUrl":"10.3390/ijerph22071129","url":null,"abstract":"<p><strong>Purpose: </strong>This exploratory retrospective analysis examined racial disparities in fall-related injuries among Black and White breast cancer survivors who received chemotherapy, focusing on the risks associated with specific chemotherapy regimens.</p><p><strong>Methods: </strong>Using real-world data from the TriNetX research platform, we analyzed a cohort of 3223 Stage I-III breast cancer survivors with complete data on race, chemotherapy exposure, and fall-related injuries. The final sample included only Black and White patients treated with chemotherapy between 1 January 2019 and 31 December 2023. Fall events within six months post-chemotherapy were analyzed. Logistic regression models evaluated associations between chemotherapy type and fall risk by race.</p><p><strong>Results: </strong>Black breast cancer survivors experienced a significantly higher rate of fall-related injuries (14.7%) compared to White survivors (10.0%) (<i>p</i> < 0.001). The risk was especially elevated among Black patients receiving Cyclophosphamide, Docetaxel, and Carboplatin.</p><p><strong>Conclusion: </strong>This study highlights racial differences in chemotherapy-associated fall risk. While the findings are observational and limited by data availability, they underscore the need for more inclusive survivorship care and further investigation using detailed clinical and contextual variables. Real-world platforms like TriNetX can help identify early signals of disparities that merit prospective study.</p>","PeriodicalId":49056,"journal":{"name":"International Journal of Environmental Research and Public Health","volume":"22 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12295958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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