Medizinische Klinik-Intensivmedizin Und Notfallmedizin最新文献

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Regional differences, repeated use, and costs of emergency medical services in Germany. 德国紧急医疗服务的地区差异、重复使用情况和成本。
IF 1.3 4区 医学
Medizinische Klinik-Intensivmedizin Und Notfallmedizin Pub Date : 2024-09-25 DOI: 10.1007/s00063-024-01189-x
Martin Roessler, Claudia Schulte, Christoph Bobeth, Isabelle Petrautzki, Laura Korthauer, Janosch Dahmen, Danny Wende, Christian Karagiannidis
{"title":"Regional differences, repeated use, and costs of emergency medical services in Germany.","authors":"Martin Roessler, Claudia Schulte, Christoph Bobeth, Isabelle Petrautzki, Laura Korthauer, Janosch Dahmen, Danny Wende, Christian Karagiannidis","doi":"10.1007/s00063-024-01189-x","DOIUrl":"https://doi.org/10.1007/s00063-024-01189-x","url":null,"abstract":"<p><strong>Background: </strong>Little is known about regional differences regarding the utilization and costs of emergency medical services (EMS) in Germany. Evidence on characteristics of repeated use of EMS is also scarce.</p><p><strong>Objectives: </strong>To compare German federal states regarding the utilization and costs of EMS and to analyze characteristics of repeated EMS use.</p><p><strong>Materials and methods: </strong>We used BARMER health insurance data on more than 1.4 million German EMS cases in 2022. We estimated EMS use rates (per 1000 inhabitants) and median reimbursements and costs by EMS type (ground transport with/without emergency physician (EP); helicopter emergency medical services), hospitalization status, and federal state. We applied Poisson regression to estimate incidence rate ratios (IRRs) with 95% confidence intervals (95% CI), capturing relationships between repeated use of EMS and individual characteristics, including care degree and income level.</p><p><strong>Results: </strong>Ground transport EMS use rates varied between federal states by more than 2.6-fold without EP (Bavaria: 84.6; Berlin: 223.2) and 2.1-fold with EP (Bremen: 19.1; Saxony: 41.3). Median reimbursement of ground transport with EP was 132% higher in Schleswig-Holstein (€ 1530) compared with Berlin (€ 660). Approximately one-third of all persons used EMS more than once and accounted for two-thirds of all EMS cases. Repeated EMS use was strongly related to care degree (IRR of care degree 5: 3084; 95% CI 3.012-3.158) and low income (IRR: 1.174; 95% CI 1.161-1.189).</p><p><strong>Conclusions: </strong>The substantial regional heterogeneity in terms of utilization and costs of EMS calls for a nationwide, consistent regulation of EMS in Germany. Additionally, (outpatient) primary nursing care of persons with severe health impairments and health literacy should be strengthened.</p>","PeriodicalId":49019,"journal":{"name":"Medizinische Klinik-Intensivmedizin Und Notfallmedizin","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142330672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient- vs organ-based prognostic tools for older patients in critical care units : An observational study with a 3-month follow-up. 重症监护室老年患者基于患者与器官的预后工具 :一项为期 3 个月的随访观察研究。
IF 1.3 4区 医学
Medizinische Klinik-Intensivmedizin Und Notfallmedizin Pub Date : 2024-09-25 DOI: 10.1007/s00063-024-01179-z
Melanie Hochleitner, Lena Pickert, Nick A Nolting, Anna Maria Affeldt, Ingrid Becker, Thomas Benzing, Matthias Kochanek, Maria Cristina Polidori
{"title":"Patient- vs organ-based prognostic tools for older patients in critical care units : An observational study with a 3-month follow-up.","authors":"Melanie Hochleitner, Lena Pickert, Nick A Nolting, Anna Maria Affeldt, Ingrid Becker, Thomas Benzing, Matthias Kochanek, Maria Cristina Polidori","doi":"10.1007/s00063-024-01179-z","DOIUrl":"https://doi.org/10.1007/s00063-024-01179-z","url":null,"abstract":"<p><strong>Background: </strong>Anticipating a doubling of older adults in Europe by 2050, healthcare systems face substantial challenges, particularly in critical care units. However, there is still a lack of evidence-based knowledge for treating and assessing mortality risk in older patients. This study compared the predictive accuracy of two assessment tools for long-term outcomes among older patients: the Multidimensional Prognostic Index (MPI) and the Sequential Organ Failure Assessment (SOFA). As the MPI is based on a more holistic assessment, it may provide a more accurate prediction than the organ-based SOFA.</p><p><strong>Objective: </strong>Does the MPI provide a more accurate prediction of mortality risk and quality of life for older patients in critical care units than the organ-based SOFA score?</p><p><strong>Methods: </strong>In a 6-month study, 96 patients aged 65 and older admitted to intensive (ICU) or intermediate care units (IMC) were enrolled to assess 90-day mortality using a comprehensive geriatric assessment-based MPI and the SOFA score. The follow-up (FU) involved telephone assessments 30 and 90 days after admission, focusing on posthospitalization health and quality of life.</p><p><strong>Results: </strong>Both MPI (p = 0.039) and SOFA score (p = 0.014) successfully predicted mortality among older IMC and ICU patients in logistic regressions. Receiver operating characteristic (ROC) analyses demonstrated comparable areas under the curve (AUCs) for MPI (0.618) and SOFA score (0.621), as well as a similar sensitivity and specificity (MPI 61.0% and 52.9%; SOFA score: 68.9% and 45.1%, respectively). The MPI at admission moreover correlated significantly with quality of life (p < 0.001, r = -0.631 at discharge; p = 0.005, r = -0.377 at 30-day FU; p = 0.004, r = -0.409 at 90-day FU) and nursing needs (Mann-Whitney U‑test, p = 0.002 at 30-day FU; p = 0.011 at 90-day FU) at FU, while the SOFA score did not show significant associations with respect to these parameters.</p><p><strong>Conclusions: </strong>In geriatric critical care, both the MPI and the SOFA score effectively predict mortality risk. While the SOFA score may appear more practical due to its simpler and faster implementation, only the MPI demonstrated significant correlations with quality of life and nursing needs in the FU after 30 and 90 days.</p>","PeriodicalId":49019,"journal":{"name":"Medizinische Klinik-Intensivmedizin Und Notfallmedizin","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142330671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Representation of women in senior positions in emergency medicine]. [妇女在急诊医学高级职位中的代表性]。
IF 16.4 4区 医学
Medizinische Klinik-Intensivmedizin Und Notfallmedizin Pub Date : 2024-09-24 DOI: 10.1007/s00063-024-01181-5
Nadja Spitznagel, Christine Hidas, Sylvia Schacher
{"title":"[Representation of women in senior positions in emergency medicine].","authors":"Nadja Spitznagel, Christine Hidas, Sylvia Schacher","doi":"10.1007/s00063-024-01181-5","DOIUrl":"10.1007/s00063-024-01181-5","url":null,"abstract":"<p><strong>Background: </strong>Gender equality and the empowerment of women is one of the 17 Sustainable Development Goals formulated by the United Nations. Gender-specific inequalities still exist, especially in medicine. Women are particularly lacking in leadership positions and in visible roles outside of patient care, such as at conferences and in scientific journals.</p><p><strong>Aim: </strong>The aim of the study was to analyse the proportion of women in leadership positions in emergency medicine and the visible roles at emergency medicine conferences and scientific journals.</p><p><strong>Materials and methods: </strong>A selective literature search in PubMed and an evaluation of the conference programmes from 2020-2021 as well as the editorial boards of journals were conducted with regard to the proportion of women.</p><p><strong>Results: </strong>Women continue to be significantly underrepresented on the editorial boards of emergency medicine journals and on the boards of leading emergency medicine organisations. Internationally, there are already programmes to increase the proportion of women in field of publications and scientific conferences; to date, there are only a few such programmes for women in emergency medicine in Germany.</p><p><strong>Conclusion: </strong>Women in healthcare in general and in emergency medicine in particular are not equally represented outside of patient care. To date, there are hardly any programmes to promote women in emergency medicine in Germany. Mentoring, collegial support and organisational change are key to increasing the proportion of women in nonpatient care roles in emergency medicine.</p>","PeriodicalId":49019,"journal":{"name":"Medizinische Klinik-Intensivmedizin Und Notfallmedizin","volume":" ","pages":""},"PeriodicalIF":16.4,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142308877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Multimorbidity as a predictor for inpatient admission in clinical emergency and acute medicine : Single-center cluster analysis]. [临床急诊科住院病人的多病症预测因素:单中心聚类分析]。
IF 1.3 4区 医学
Medizinische Klinik-Intensivmedizin Und Notfallmedizin Pub Date : 2024-09-11 DOI: 10.1007/s00063-024-01180-6
E Grüneberg, R Fliedner, T Beißbarth, C A F von Arnim, S Blaschke
{"title":"[Multimorbidity as a predictor for inpatient admission in clinical emergency and acute medicine : Single-center cluster analysis].","authors":"E Grüneberg, R Fliedner, T Beißbarth, C A F von Arnim, S Blaschke","doi":"10.1007/s00063-024-01180-6","DOIUrl":"https://doi.org/10.1007/s00063-024-01180-6","url":null,"abstract":"<p><strong>Background: </strong>Parallel to demographic trends, an increase of multimorbid patients in emergency and acute medicine is prominent. To define easily applicable criteria for the necessity of inpatient admission, a hierarchical cluster analysis was performed.</p><p><strong>Methods: </strong>In a retrospective, single-center study data of n = 35,249 emergency cases (01/2016-05/2018) were statistically analyzed. Multimorbidity (MM) was defined by at least five ICD-10-GM diagnoses resulting from treatment. A hierarchical cluster analysis was performed for those diagnoses initially summarized into 112 diagnosis subclusters to determine specific clusters of in- and outpatient cases.</p><p><strong>Results: </strong>Hospital admission was determined in 81.2% of all ED patients (n = 28,633); 54.7% of inpatients (n = 15,652) and 0.97% of outpatient cases (n = 64) met the criteria for multimorbidity and the age difference between them was highly significant (68.7/60.8 years; p < 0.001). Using a hierarchical cluster analysis, 13 clusters with different diagnoses were identified for inpatient multimorbid patients (MP) and 7 clusters with primarily hematological malignancies for outpatient MP. The length of stay in the ED of inpatient MP was more than twice as long (max. 8.3 h) as for outpatient MP (max. 3.2 h.).</p><p><strong>Conclusions: </strong>The combination of diagnoses typical for MM were characterized as clusters in this study. In contrast to single or combined single diagnoses, the statistically determined characterization of clusters allows for a significantly more accurate prediction of ED patients' disposition as well as for economic process allocation.</p>","PeriodicalId":49019,"journal":{"name":"Medizinische Klinik-Intensivmedizin Und Notfallmedizin","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Passive leg raising test versus rapid fluid challenge in critically ill medical patients. 重症内科病人的被动抬腿试验与快速输液挑战。
IF 1.3 4区 医学
Medizinische Klinik-Intensivmedizin Und Notfallmedizin Pub Date : 2024-09-06 DOI: 10.1007/s00063-024-01176-2
Natascha Majunke, Dan Philipp, Lorenz Weidhase, Bastian Pasieka, Kevin Kunz, Frank Seidel, Robert Scharm, Sirak Petros
{"title":"Passive leg raising test versus rapid fluid challenge in critically ill medical patients.","authors":"Natascha Majunke, Dan Philipp, Lorenz Weidhase, Bastian Pasieka, Kevin Kunz, Frank Seidel, Robert Scharm, Sirak Petros","doi":"10.1007/s00063-024-01176-2","DOIUrl":"https://doi.org/10.1007/s00063-024-01176-2","url":null,"abstract":"<p><strong>Background: </strong>The passive leg raising (PLR) test is a simple test to detect preload responsiveness. However, variable fluid doses and infusion times were used in studies evaluating the effect of PLR. Studies showed that the effect of fluid challenge on hemodynamics dissipates in 10 min. This prospective study aimed to compare PLR and a rapid fluid challenge (RFC) with a 300-ml bolus infused within 5 min in adult patients with a hemodynamic compromise.</p><p><strong>Materials and methods: </strong>Critically ill medical patients with signs of systemic hypoperfusion were included if volume expansion was considered. Hemodynamic status was assessed with continuous measurements of cardiac output (CO), when possible, and mean arterial pressure (MAP) at baseline, during PLR, and after RFC.</p><p><strong>Results: </strong>A total of 124 patients with a median age of 65.0 years were included. Their acute physiology and chronic health evaluation (APACHE) II score was 19.7 ± 6.0, with a sequential organ failure assessment (SOFA) score of 9.0 ± 4.4. Sepsis was diagnosed in 73.3%, and 79.8% of the patients were already receiving a norepinephrine infusion. Invasive MAP monitoring was established in all patients, while continuous CO recording was possible in 42 patients (33.9%). Based on CO changes, compared with those with RFC, the false positive and false negative rates with PLR were 21.7 and 36.8%, respectively, with positive and negative predictive values of 70.6 and 72.0%, respectively. Based on MAP changes, compared with those with RFC, the false positive and false negative rates with PLR compared to RFC were 38.2% and 43.3%, respectively, with positive and negative predictive values of 64.4 and 54.0%, respectively.</p><p><strong>Conclusion: </strong>This study demonstrated a moderate agreement between PLR and RFC in hemodynamically compromised medical patients, which should be considered when testing preload responsiveness.</p>","PeriodicalId":49019,"journal":{"name":"Medizinische Klinik-Intensivmedizin Und Notfallmedizin","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142141500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Skill-grade mix and shared governance in the intensive care unit: development of a management triangle and the advancement of nursing roles]. [重症监护病房的技能等级组合与共同治理:管理三角的发展与护理角色的提升]。
IF 1.3 4区 医学
Medizinische Klinik-Intensivmedizin Und Notfallmedizin Pub Date : 2024-09-04 DOI: 10.1007/s00063-024-01175-3
Christian Siegling, Esther Mertins, Franziska Wefer, Christina Bolte, Lars Krüger
{"title":"[Skill-grade mix and shared governance in the intensive care unit: development of a management triangle and the advancement of nursing roles].","authors":"Christian Siegling, Esther Mertins, Franziska Wefer, Christina Bolte, Lars Krüger","doi":"10.1007/s00063-024-01175-3","DOIUrl":"https://doi.org/10.1007/s00063-024-01175-3","url":null,"abstract":"<p><strong>Background: </strong>In the Federal Republic of Germany, it has been possible for some years to study (intensive) nursing care alongside further training in intensive care and anaesthesia. This results in a nursing skill-grade mix in the intensive care unit (ICU), which nursing management must consider.</p><p><strong>Objectives: </strong>The aim is to show the development and implementation of a new nursing management structure in the ICU and also provide an overview of the parallel role development with preliminary results at a university hospital.</p><p><strong>Materials and methods: </strong>Within a working group of nursing management, a narrative analysis of the current situation was carried out with close involvement of the ICU ward managers and the staff units for nursing development, further education and nursing education. The content was organized into subject areas and a new management model was subsequently developed. The evaluation took place narratively within the context of employee interviews.</p><p><strong>Results: </strong>The management model in the ICU was divided into the areas of nursing management, nursing education, and nursing science as a management triangle. Nursing management is staffed by at least two people as ward managers and deputies, while the nursing education and science team leaders have equal decision-making powers in terms of shared governance. The respective specialist departments work together within the hospital in networks with other ICUs. Other specialist roles such as primary nurses, advanced practice nurses, heart failure nurses or practical instructors are given specific contact persons in the management team to match their tasks, which was viewed positively.</p><p><strong>Conclusions: </strong>The development of nursing practice can be promoted through close co-operation within the management team.</p>","PeriodicalId":49019,"journal":{"name":"Medizinische Klinik-Intensivmedizin Und Notfallmedizin","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Extracorporeal treatment in poisoning]. [中毒的体外治疗]。
IF 1.3 4区 医学
Medizinische Klinik-Intensivmedizin Und Notfallmedizin Pub Date : 2024-09-01 Epub Date: 2024-07-10 DOI: 10.1007/s00063-024-01156-6
Gerald Hackl, Nikolaus Schreiber
{"title":"[Extracorporeal treatment in poisoning].","authors":"Gerald Hackl, Nikolaus Schreiber","doi":"10.1007/s00063-024-01156-6","DOIUrl":"10.1007/s00063-024-01156-6","url":null,"abstract":"<p><p>In rare cases, intoxicated patients may require an extracorporeal procedure for enhanced toxin elimination. The Extracorporeal Treatments in Poisoning (EXTRIP) workgroup provides consensus- and evidence-based recommendations regarding the use of extracorporeal procedures in the management of critically ill, poisoned patients, with ongoing updates. Extracorporeal clearance is highest for low molecular weight substances with low volume of distribution, low plasma protein binding, and high water-solubility. To maximize the effect of extracorporeal clearance, blood and dialysate flow rates should be as high as possible, and the membrane with the largest surface area should be utilized. Intermittent hemodialysis is the most commonly employed extracorporeal procedure due to its highest effectiveness, while hemodynamically compromised patients can benefit from a continuous procedure.</p>","PeriodicalId":49019,"journal":{"name":"Medizinische Klinik-Intensivmedizin Und Notfallmedizin","volume":" ","pages":"511-520"},"PeriodicalIF":1.3,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11405442/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141564889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mitteilungen der DGIIN. DGIIN 的通信。
IF 1.3 4区 医学
Medizinische Klinik-Intensivmedizin Und Notfallmedizin Pub Date : 2024-09-01 DOI: 10.1007/s00063-024-01178-0
{"title":"Mitteilungen der DGIIN.","authors":"","doi":"10.1007/s00063-024-01178-0","DOIUrl":"10.1007/s00063-024-01178-0","url":null,"abstract":"","PeriodicalId":49019,"journal":{"name":"Medizinische Klinik-Intensivmedizin Und Notfallmedizin","volume":"119 6","pages":"521-528"},"PeriodicalIF":1.3,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Ten key statements of the S3 guideline "Epidemiology, diagnosis, and treatment of adult patients with nosocomial pneumonia"]. [S3指南 "成人非典型肺炎患者的流行病学、诊断和治疗 "的十项关键声明]。
IF 1.3 4区 医学
Medizinische Klinik-Intensivmedizin Und Notfallmedizin Pub Date : 2024-09-01 Epub Date: 2024-07-10 DOI: 10.1007/s00063-024-01159-3
Jessica Rademacher, Stefan Kluge
{"title":"[Ten key statements of the S3 guideline \"Epidemiology, diagnosis, and treatment of adult patients with nosocomial pneumonia\"].","authors":"Jessica Rademacher, Stefan Kluge","doi":"10.1007/s00063-024-01159-3","DOIUrl":"10.1007/s00063-024-01159-3","url":null,"abstract":"","PeriodicalId":49019,"journal":{"name":"Medizinische Klinik-Intensivmedizin Und Notfallmedizin","volume":" ","pages":"502-505"},"PeriodicalIF":1.3,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141564890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Bleeding in liver diseases]. [肝病出血]。
IF 1.3 4区 医学
Medizinische Klinik-Intensivmedizin Und Notfallmedizin Pub Date : 2024-09-01 Epub Date: 2024-08-13 DOI: 10.1007/s00063-024-01167-3
Andreas Drolz
{"title":"[Bleeding in liver diseases].","authors":"Andreas Drolz","doi":"10.1007/s00063-024-01167-3","DOIUrl":"10.1007/s00063-024-01167-3","url":null,"abstract":"<p><p>Bleeding events are feared complications in patients with advanced liver diseases and are associated with morbidity and mortality. In this context, gastrointestinal bleeding, particularly upper gastrointestinal bleeding, has a special clinical importance. In addition to endoscopic measures for hemostasis, reducing portal pressure in particular is a key component of treatment. Although the standard coagulation parameters are often altered in patients with liver diseases, optimizing coagulation plays a secondary role. Typically, a bundle of measures are employed in patients with portal hypertensive bleeding, which nowadays in most cases can halt the bleeding and stabilize the situation. The measures include endoscopy, antibiotic treatment, vasopressor treatment and, if necessary, shunt placement (transjugular intrahepatic portosystemic shunt).</p>","PeriodicalId":49019,"journal":{"name":"Medizinische Klinik-Intensivmedizin Und Notfallmedizin","volume":" ","pages":"458-464"},"PeriodicalIF":1.3,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141976984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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