Primary Care Diabetes最新文献

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Continuous glucose monitoring patterns among pregnant individuals with varying levels of glucose intolerance 不同程度葡萄糖耐受不良孕妇的连续血糖监测模式
IF 2.3 4区 医学
Primary Care Diabetes Pub Date : 2026-02-01 Epub Date: 2025-12-03 DOI: 10.1016/j.pcd.2025.11.006
Rachel D. Gordon , Jiqiang Wu , Jennifer Grasch , Neeharika Nandam , Patrick Schneider , Steven Gabbe , Mark B. Landon , Maged M. Costantine , Kartik K. Venkatesh , Elizabeth O. Buschur
{"title":"Continuous glucose monitoring patterns among pregnant individuals with varying levels of glucose intolerance","authors":"Rachel D. Gordon ,&nbsp;Jiqiang Wu ,&nbsp;Jennifer Grasch ,&nbsp;Neeharika Nandam ,&nbsp;Patrick Schneider ,&nbsp;Steven Gabbe ,&nbsp;Mark B. Landon ,&nbsp;Maged M. Costantine ,&nbsp;Kartik K. Venkatesh ,&nbsp;Elizabeth O. Buschur","doi":"10.1016/j.pcd.2025.11.006","DOIUrl":"10.1016/j.pcd.2025.11.006","url":null,"abstract":"<div><div>We conducted a prospective observational cohort of pregnant individuals to compare continuous glucose monitoring trends between pregnant individuals with varying levels of glucose intolerance. We found that individuals who had an abnormal value on an oral glucose tolerance test had similar glucose trends to those with gestational diabetes mellitus</div></div>","PeriodicalId":48997,"journal":{"name":"Primary Care Diabetes","volume":"20 1","pages":"Pages 133-136"},"PeriodicalIF":2.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145673000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Achieving pregnancy glycemic targets and postpartum depressive symptoms among individuals with pregestational diabetes 妊娠糖尿病患者实现妊娠血糖目标和产后抑郁症状
IF 2.3 4区 医学
Primary Care Diabetes Pub Date : 2026-02-01 Epub Date: 2025-12-19 DOI: 10.1016/j.pcd.2025.12.006
Jenna Meiman , Abigail Steinbrunner , Naleef Fareed , Joshua J. Joseph , Mark B. Landon , William A. Grobman , Kartik K. Venkatesh
{"title":"Achieving pregnancy glycemic targets and postpartum depressive symptoms among individuals with pregestational diabetes","authors":"Jenna Meiman ,&nbsp;Abigail Steinbrunner ,&nbsp;Naleef Fareed ,&nbsp;Joshua J. Joseph ,&nbsp;Mark B. Landon ,&nbsp;William A. Grobman ,&nbsp;Kartik K. Venkatesh","doi":"10.1016/j.pcd.2025.12.006","DOIUrl":"10.1016/j.pcd.2025.12.006","url":null,"abstract":"<div><div>We determined whether achieving glycemic control during pregnancy was associated with fewer postpartum depressive symptoms among individuals with pregestational diabetes. We found achievement of pregnancy glycemic targets was not associated with a lower risk of postpartum depressive symptoms in a population with a high frequency of pre-existing psychiatric morbidity.</div></div>","PeriodicalId":48997,"journal":{"name":"Primary Care Diabetes","volume":"20 1","pages":"Pages 137-139"},"PeriodicalIF":2.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145795508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Routine HbA1c monitoring and cardiovascular outcomes in diabetes: Evidence from a large Spanish cohort 糖尿病患者常规HbA1c监测与心血管结局:来自西班牙大型队列的证据
IF 2.3 4区 医学
Primary Care Diabetes Pub Date : 2026-02-01 Epub Date: 2025-12-16 DOI: 10.1016/j.pcd.2025.11.012
Domingo Orozco-Beltran , Samuel Seidu , Jose Antonio Quesada
{"title":"Routine HbA1c monitoring and cardiovascular outcomes in diabetes: Evidence from a large Spanish cohort","authors":"Domingo Orozco-Beltran ,&nbsp;Samuel Seidu ,&nbsp;Jose Antonio Quesada","doi":"10.1016/j.pcd.2025.11.012","DOIUrl":"10.1016/j.pcd.2025.11.012","url":null,"abstract":"<div><h3>AIM</h3><div>Glycated hemoglobin (HbA<sub>1c</sub>) is a key indicator of diabetes control. However, the risk of missing HbA<sub>1c</sub> values in clinical records is unknown. We aimed to analyze the relationship between missing HbA<sub>1c</sub> values and the occurrence of major cardiovascular events or death from all causes.</div></div><div><h3>Methods</h3><div>Retrospective cohort study based on a national database of primary care electronic medical records in Spain (BIFAP). We included people aged 30 years and older with an incident diagnosis of diabetes mellitus. Follow-up started on the date of diabetes diagnosis between 2005 and 2019, and ended on occurrence of composite endpoint (major cardiovascular events and/or death from all causes), or <em>December 31st</em>, 2019. The baseline exposure variable was HbA<sub>1c</sub> (&lt; 7 %, 7 %–8 %, &gt; 8 %, missing). Cox models were fitted.</div></div><div><h3>Results</h3><div>Our analysis included 303,199 people with diabetes, with an average age of 62.2 years and 44.7 % were women. The mean follow-up was 5.7 years, and 10.2 % of patients had missing HbA<sub>1c</sub> values. The cardiovascular risk was 1.18 (95 %CI: 1.14–1.22) in the HbA<sub>1c</sub> 7 %-8 % group, 1.41 (95 %CI: 1.36–1.46) in HbA<sub>1c</sub> &gt; 8 %, and 2.95 (95 %CI: 2.89–3.05) in HbA<sub>1c</sub> missing, compared with HbA<sub>1c</sub> &lt; 7 %.</div></div><div><h3>Conclusions</h3><div>In this large cohort of people with newly diagnosed diabetes, missing HbA1c values was associated with a significantly higher risk of major cardiovascular events or death, more than double the risk observed in people with the worst glycemic control. These findings underscore the clinical importance of routinely recording and monitoring HbA1c at diagnosis, not only as a marker of metabolic control but also as a potential prognostic indicator. The lack of HbA1c may act as an indicator of suboptimal clinical follow-up.</div></div>","PeriodicalId":48997,"journal":{"name":"Primary Care Diabetes","volume":"20 1","pages":"Pages 13-20"},"PeriodicalIF":2.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145776969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of an online self-management programme for type 2 diabetes. The BEATdiabetes prospective service evaluation 在线自我管理程序对2型糖尿病的影响。BEATdiabetes前瞻性服务评价。
IF 2.3 4区 医学
Primary Care Diabetes Pub Date : 2026-02-01 Epub Date: 2025-10-27 DOI: 10.1016/j.pcd.2025.10.005
S. Carrod , M.B. Whyte , K. Bennett-Eastley , P. Grob , C. Steacy , M. Shabbir , M. Glover , J. Harris , K. Hart , H. Gage , M. Stedman , A. Heald , D. Cooke
{"title":"The impact of an online self-management programme for type 2 diabetes. The BEATdiabetes prospective service evaluation","authors":"S. Carrod ,&nbsp;M.B. Whyte ,&nbsp;K. Bennett-Eastley ,&nbsp;P. Grob ,&nbsp;C. Steacy ,&nbsp;M. Shabbir ,&nbsp;M. Glover ,&nbsp;J. Harris ,&nbsp;K. Hart ,&nbsp;H. Gage ,&nbsp;M. Stedman ,&nbsp;A. Heald ,&nbsp;D. Cooke","doi":"10.1016/j.pcd.2025.10.005","DOIUrl":"10.1016/j.pcd.2025.10.005","url":null,"abstract":"<div><h3>Aims</h3><div>To deliver and evaluate online, supported self-management interventions (BEATdiabetes) designed to promote lifestyle change and reduce psychological distress in type 2 diabetes (T2D).</div></div><div><h3>Design &amp; methods</h3><div>A prospective service evaluation of BEATdiabetes, delivered within primary care in the National Health Service (NHS), 2019–2021. Primary outcome was absolute change in HbA1c and secondary outcomes were BMI, blood pressure (BP) and total cholesterol (TC) analysed using adjusted regression models. Pre- and post-analysis of the Diabetes Distress Scale (DDS) in the BEATdiabetes group only. The comparator population was The Salford Integrated Record (SIR, Salford, UK) diabetes cohort (no access to BEATdiabetes); matched by age, sex, ethnicity and BMI. Odds ratios (OR) evaluated achievement of clinical targets according to national guidelines.</div></div><div><h3>Results</h3><div>BEATdiabetes (n = 574) followed for median 217 days (interquartile range [IQR] 158–328); comparator group 241 days (IQR 187–328). BEATdiabetes had greater change in mean HbA1c (0.3 % DCCT; −3.3 mmol/mol; 95 % confidence interval [CI] −4.7 to −1.9 mmol/mol), BMI (-0.81 kg/m<sup>2</sup>; 95 % CI −1.07 to −0.54), systolic BP (-2.8 mmHg; 95 % CI −4.3 to −1.3; all P &lt; 0.001), and diastolic BP (-1.3 mmHg; 95 % CI −2.3 to −0.3; P &lt; 0.01). At baseline, n = 58 had DDS of ≥ 2 and n = 39 at follow-up (P = 0.023). BEATdiabetes had greater achievement target BP (OR 1.69 [95 % CI 1.28–2.24]), HbA1c (OR 1.79 [95 % CI 1.33–2.42]) and TC (OR 0.71 [95 % CI 0.50–0.99]). Estimated average cost per intervention was £ 149; 2021/2).</div></div><div><h3>Conclusions</h3><div>Combined online nutritional, psychological and behavioural intervention was more effective for weight and glycaemic reduction among adults with T2D, compared with usual care, with associated reduction in DDS.</div></div>","PeriodicalId":48997,"journal":{"name":"Primary Care Diabetes","volume":"20 1","pages":"Pages 21-29"},"PeriodicalIF":2.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145395170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mortality in offspring of women with type 1 diabetes during pregnancy 妊娠期1型糖尿病妇女后代的死亡率。
IF 2.3 4区 医学
Primary Care Diabetes Pub Date : 2026-02-01 Epub Date: 2025-12-18 DOI: 10.1016/j.pcd.2025.12.004
Erik Somersalo , Cedric Korpijaakko , Mia D. Eriksson , Miira M. Klemetti , Hannu Kautiainen , Johan G. Eriksson , Merja K. Laine
{"title":"Mortality in offspring of women with type 1 diabetes during pregnancy","authors":"Erik Somersalo ,&nbsp;Cedric Korpijaakko ,&nbsp;Mia D. Eriksson ,&nbsp;Miira M. Klemetti ,&nbsp;Hannu Kautiainen ,&nbsp;Johan G. Eriksson ,&nbsp;Merja K. Laine","doi":"10.1016/j.pcd.2025.12.004","DOIUrl":"10.1016/j.pcd.2025.12.004","url":null,"abstract":"<div><h3>Aims</h3><div>Fetal and neonatal complications are common in pregnancies affected by maternal type 1 diabetes. The aim of this study is to investigate whether type 1 diabetes during pregnancy is reflected in offspring long-term mortality during a follow-up of up to 30 years.</div></div><div><h3>Methods</h3><div>This register-based follow-up study included 1762 offspring of women with type 1 diabetes (cases) and 8810 offspring of women without diabetes (controls). Time and causes of death between 1988 and 2018 were obtained from Statistics Finland. Clinical characteristics at birth of study participants and their mothers were obtained from the Finnish Medical Birth Register.</div></div><div><h3>Results</h3><div>Cases had an 1,67 times higher mortality than controls during the 30-year follow-up period (crude HR 1.67 [95 % CI: 1.01–2.77]), with a median follow-up of 21 years (IQR 15–28). Cases possessed an adverse risk-profile at the neonatal stage. Endocrine, nutritional and metabolic diseases (IRR 5.02/100 000 person years [95 % CI 1.01–24.88]), and diseases of the nervous system (IRR 5.03/100 000 person years [95 % CI 1.16–21.82]) were overrepresented as the cause of death in this group.</div></div><div><h3>Conclusions</h3><div>These findings suggest that maternal type 1 diabetes during pregnancy is associated with higher mortality during a 30-year follow-up.</div></div>","PeriodicalId":48997,"journal":{"name":"Primary Care Diabetes","volume":"20 1","pages":"Pages 127-132"},"PeriodicalIF":2.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145795552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of smart watch mobile application on the risk treatment of type 2 diabetes mellitus (iSMART-DM) 智能手表移动应用对2型糖尿病(iSMART-DM)风险治疗的影响
IF 2.3 4区 医学
Primary Care Diabetes Pub Date : 2026-02-01 Epub Date: 2025-10-27 DOI: 10.1016/j.pcd.2025.10.008
Min Kyoung Jang, Yun Kyung Cho, Jung Yoon Moon, Se Hee Min, Ju Hee Hwang, Chang Hee Jung
{"title":"Impact of smart watch mobile application on the risk treatment of type 2 diabetes mellitus (iSMART-DM)","authors":"Min Kyoung Jang,&nbsp;Yun Kyung Cho,&nbsp;Jung Yoon Moon,&nbsp;Se Hee Min,&nbsp;Ju Hee Hwang,&nbsp;Chang Hee Jung","doi":"10.1016/j.pcd.2025.10.008","DOIUrl":"10.1016/j.pcd.2025.10.008","url":null,"abstract":"<div><div>Mobile health (mHealth) interventions incorporating smartwatches and personalized coaching show promise in improving diabetes self-management. Although studies report modest glycemic benefits and behavioral improvements from app-based interventions, real-world data from East Asian populations remain limited.</div></div><div><h3>Aims</h3><div>To evaluate the effectiveness of a smartwatch-based, app-linked lifestyle intervention (iSMART-DM) in improving glycemic control and self-care behavior in patients with non-insulin-treated type 2 diabetes mellitus (T2DM).</div></div><div><h3>Methods</h3><div>In a 12-week, open-label randomized controlled trial, 80 adults with T2DM were randomized in a 2:1 ratio to an intervention group (n = 54; smartwatch + mobile app + structured education) or a control group (n = 26; structured education alone). The primary endpoint was the change in glycated hemoglobin (HbA1c). Secondary endpoints included fasting plasma glucose (FPG), HbA1c target attainment (&lt;6.5 %), and changes in self-care behavior scores using the Summary of Diabetes Self-Care Activities Questionnaire (SDSCA-K). Satisfaction and adherence to the digital health intervention were also assessed.</div></div><div><h3>Results</h3><div>After 12 weeks, the mean HbA1c change was −0.14 % and −0.13 % in the intervention and control groups, respectively (p = 0.837). No significant differences were observed in FPG change or HbA1c target attainment. However, the intervention group showed significantly greater improvement in SDSCA-K scores (+9.7 points; 95 % CI 4.0–15.6; p = 0.001), particularly in diet and physical activity. User satisfaction with the mobile platform was high, with &gt; 85 % reporting a positive effect on daily health management.</div></div><div><h3>Conclusions</h3><div>Although short-term glycemic control showed no significant difference, the smartwatch-based mobile intervention significantly enhanced self-care behaviors in patients with T2DM. These findings highlight the behavioral benefits of wearable-integrated mHealth platforms and support their broader application in lifestyle modification strategies</div></div>","PeriodicalId":48997,"journal":{"name":"Primary Care Diabetes","volume":"20 1","pages":"Pages 47-52"},"PeriodicalIF":2.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145380553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of pay-for-performance programs on hospitalization risks in subjects with type 1 diabetes mellitus: A nationwide cohort study 绩效薪酬计划对1型糖尿病患者住院风险的影响:一项全国性队列研究
IF 2.3 4区 医学
Primary Care Diabetes Pub Date : 2026-02-01 Epub Date: 2025-11-28 DOI: 10.1016/j.pcd.2025.11.011
Yun-Kai Yeh , Fu-Shun Yen , James Cheng-Chung Wei , Yi-Ting Tsai , Heng-Jun Lin , Ying-Hsiu Shih , Chih-Cheng Hsu , Chii-Min Hwu
{"title":"The impact of pay-for-performance programs on hospitalization risks in subjects with type 1 diabetes mellitus: A nationwide cohort study","authors":"Yun-Kai Yeh ,&nbsp;Fu-Shun Yen ,&nbsp;James Cheng-Chung Wei ,&nbsp;Yi-Ting Tsai ,&nbsp;Heng-Jun Lin ,&nbsp;Ying-Hsiu Shih ,&nbsp;Chih-Cheng Hsu ,&nbsp;Chii-Min Hwu","doi":"10.1016/j.pcd.2025.11.011","DOIUrl":"10.1016/j.pcd.2025.11.011","url":null,"abstract":"<div><h3>Aims</h3><div>This retrospective cohort study aimed to investigate the impact of pay-for-performance programs (P4P) on hospitalization rates in individuals with type 1 diabetes mellitus (T1D).</div></div><div><h3>Methods</h3><div>Using propensity score matching, we recruited 625 pairs of individuals with T1D with and without P4P care from the National Health Insurance Research Database of Taiwan between January 1, 2006, and December 31, 2018. The study used a multivariable Cox regression model to compare the risks of hospitalization for various reasons in individuals with T1D with and without P4P care.</div></div><div><h3>Results</h3><div>Individuals with T1D receiving pay-for-performance (P4P) care demonstrated a significantly lower risk of all-cause hospitalization (adjusted hazard ratio [aHR] 0.63, 95 % confidence interval [CI] 0.54–0.73). This reduction was particularly notable for hospitalizations related to glucose management or metabolic disorders, infectious diseases, pneumonia, circulatory and respiratory system diseases, and mental health, compared with those not receiving P4P care. However, no significant differences were observed in hospitalization risks for hyperglycemic crisis, severe hypoglycemia, or injury between individuals with and without P4P care.</div></div><div><h3>Conclusions</h3><div>This nationwide cohort study found that P4P participation was associated with a lower risk of hospitalization in individuals with type 1 diabetes.</div></div>","PeriodicalId":48997,"journal":{"name":"Primary Care Diabetes","volume":"20 1","pages":"Pages 68-73"},"PeriodicalIF":2.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145644130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Time-restricted eating and circadian rhythms: A new frontier in diabetes and obesity management 限时饮食和昼夜节律:糖尿病和肥胖管理的新前沿。
IF 2.3 4区 医学
Primary Care Diabetes Pub Date : 2026-02-01 Epub Date: 2025-11-22 DOI: 10.1016/j.pcd.2025.11.004
Sammra Maqsood , Saiqa Amjad , Faiyaz Ahmed , Md Faruque Ahmad
{"title":"Time-restricted eating and circadian rhythms: A new frontier in diabetes and obesity management","authors":"Sammra Maqsood ,&nbsp;Saiqa Amjad ,&nbsp;Faiyaz Ahmed ,&nbsp;Md Faruque Ahmad","doi":"10.1016/j.pcd.2025.11.004","DOIUrl":"10.1016/j.pcd.2025.11.004","url":null,"abstract":"<div><h3>Background</h3><div>A new feeding strategy called time-restricted eating (TRE) is being developed with the goal to remedy obesity and type 2 diabetes by aligning food consumption with the body's endogenous circadian rhythms. These rhythms regulate metabolic function on a daily 24-hour basis by exerting a significant impact on energy balance, lipid metabolism, and glucose homeostasis.</div></div><div><h3>Methods</h3><div>These databases were searched in an exhaustive manner: Scopus, Web of Science, Google Scholar, PubMed, Saudi Digital Library, and the Cochrane Library; the search was widened until January 2025. Essential search terms were: dieting on time constraint, metabolic health, the circadian rhythm, obesity, and diabetes.</div></div><div><h3>Results</h3><div>To optimize metabolic health, TRE takes advantage of circadian rhythms by restricting daily calorie consumption to a specified time window. TRE has been shown in clinical trials to enhance weight loss, insulin sensitivity, and glucose metabolism. Clinical evidence indicates that TRE can alter the disease trajectory of obese patients as well as patients with type 2 diabetes. The psychological and behavioral determinants of compliance with this intervention are also addressed in this review.</div></div><div><h3>Conclusion</h3><div>For the control of metabolic disease, TRE holds promise. For more insight into the therapeutic benefit of TRE, future studies should investigate its possible combination with individualized nutritional regimens and its long-term impact on metabolic and psychological health.</div></div>","PeriodicalId":48997,"journal":{"name":"Primary Care Diabetes","volume":"20 1","pages":"Pages 1-12"},"PeriodicalIF":2.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145590610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The U.S. diabetes belt and factors explaining the excess risk: Multifactorial modeling and machine learning analysis 美国糖尿病带和解释过度风险的因素:多因素建模和机器学习分析。
IF 2.3 4区 医学
Primary Care Diabetes Pub Date : 2026-02-01 Epub Date: 2025-12-11 DOI: 10.1016/j.pcd.2025.12.001
Longjian Liu , Nathalie S. May , Yuwei Hou , Jingyi Shi , Edward J. Gracely , Arthur L. Frank , Howard J. Eisen
{"title":"The U.S. diabetes belt and factors explaining the excess risk: Multifactorial modeling and machine learning analysis","authors":"Longjian Liu ,&nbsp;Nathalie S. May ,&nbsp;Yuwei Hou ,&nbsp;Jingyi Shi ,&nbsp;Edward J. Gracely ,&nbsp;Arthur L. Frank ,&nbsp;Howard J. Eisen","doi":"10.1016/j.pcd.2025.12.001","DOIUrl":"10.1016/j.pcd.2025.12.001","url":null,"abstract":"<div><h3>Aim</h3><div>Research on the epidemiology of diabetes mellitus (DM) has identified a geographically distinct region in the United States (U.S.) known as the diabetes belt (DM Belt), which represents a significant public health concern. This study aimed to examine the factors contributing to the increased risk of DM in the DM Belt compared to the non-DM Belt.</div></div><div><h3>Methods</h3><div>Data were analyzed from 398,243 adults aged ≥ 18 years who participated in the 2019 Behavior Risk Factor Surveillance System. DM status was based on participants’ self-reported physician-diagnosed DM. The DM Belt was defined at the state level according to the U.S. Center for Disease Control and Prevention’s classification. Logistic regression (LR) was used to estimate odds ratios for DM and assess the excess DM risk in the DM Belt versus the non-DM Belt. Random Forest (RF) and stepwise LR were employed to identify and rank key contributors to the excess DM risk.</div></div><div><h3>Results</h3><div>Residents of the DM Belt had a significantly higher prevalence of DM than those in the non-DM Belt (age-sex-adjusted rate: 12.5 % versus 10.5 %, p &lt; 0.001). Low socioeconomic status (SES), physical inactivity, and hypertension were identified as the top three factors explaining the excess DM risk in the DM Belt.</div></div><div><h3>Conclusions</h3><div>These findings underscore the importance of an integrated approach to improving SES, promoting healthy behaviors, managing chronic conditions for reducing DM risk. Addressing these factors can help mitigate health disparities in DM risk across the U.S.</div></div>","PeriodicalId":48997,"journal":{"name":"Primary Care Diabetes","volume":"20 1","pages":"Pages 99-105"},"PeriodicalIF":2.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145746569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantitative analysis of obesity predictors: Evidence from the Ravansar non-communicable disease (RaNCD) cohort study 肥胖预测因素的定量分析:来自Ravansar非传染性疾病(rand)队列研究的证据
IF 2.3 4区 医学
Primary Care Diabetes Pub Date : 2026-02-01 Epub Date: 2025-10-23 DOI: 10.1016/j.pcd.2025.10.007
Sharareh Rostam Niakan Kalhori , Farid Najafi , Seyed Mohammad Ayyoubzadeh , Fatemeh Sadat Mirebrahimzadeh , Soroush Heydari
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