Primary Care Diabetes最新文献

Comparative risk of osteoporosis in older women with type 2 diabetes receiving sodium–glucose cotransporter 2 inhibitor or dipeptidyl peptidase-4 inhibitor: A nationwide cohort study 接受钠-葡萄糖共转运蛋白2抑制剂或二肽基肽酶-4抑制剂治疗的老年2型糖尿病女性骨质疏松的比较风险：一项全国性队列研究

IF 2.3 4区医学

Primary Care Diabetes Pub Date : 2026-02-01 Epub Date: 2025-12-23 DOI: 10.1016/j.pcd.2025.12.005

Hyeon Jeong Lee, Pusoon Chun

{"title":"Comparative risk of osteoporosis in older women with type 2 diabetes receiving sodium–glucose cotransporter 2 inhibitor or dipeptidyl peptidase-4 inhibitor: A nationwide cohort study","authors":"Hyeon Jeong Lee, Pusoon Chun","doi":"10.1016/j.pcd.2025.12.005","DOIUrl":"10.1016/j.pcd.2025.12.005","url":null,"abstract":"<div><h3>Aim</h3><div>To compare osteoporosis risk associated with sodium–glucose cotransporter 2 inhibitor (SGLT2i) versus dipeptidyl peptidase-4 inhibitor (DPP-4i) in older women with type 2 diabetes (T2D).</div></div><div><h3>Methods</h3><div>This cohort study used the Korean National Health Insurance database. Adjusted hazard ratios (aHRs) were estimated using multivariable Cox regression. Sensitivity analysis was performed using inverse probability of treatment weighting (IPTW).</div></div><div><h3>Results</h3><div>Among 1715,337 women aged ≥ 55 years with T2D, 5364 SGLT2i users and 26,504 DPP-4i users were analyzed. The incidence rates of osteoporosis were 6.7 (95 % CI, 6.0–7.4) and 7.0 (95 % CI, 6.7–7.3) per 100 person-years in the SGLT2i and DPP-4i groups, respectively. Osteoporosis risk with SGLT2i was comparable to DPP-4i (aHR, 0.93; 95 % CI, 0.89–1.04). These results remained consistent in the sensitivity analysis using IPTW (aHR, 0.95; 95 % CI, 0.89–1.00). Subgroup analyses showed a slightly lower osteoporosis risk with SGLT2i in patients aged 55–64 years (aHR, 0.84; 95 % CI, 0.76–0.93), those without prior rheumatoid arthritis (aHR, 0.90; 95 % CI, 0.83–0.97), proton pump inhibitor use (aHR, 0.88; 95 % CI, 0.80–0.96), or oral corticosteroid use (aHRs, 0.91; 95 % CI, 0.85–0.97).</div></div><div><h3>Conclusion</h3><div>SGLT2i was comparable to DPP-4i in osteoporosis risk among older women with T2D.</div></div>","PeriodicalId":48997,"journal":{"name":"Primary Care Diabetes","volume":"20 1","pages":"Pages 106-114"},"PeriodicalIF":2.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145829564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Sociodemographic and behavioral factors associated with diet quality in low-income adults with prediabetes and type 2 diabetes 与糖尿病前期和2型糖尿病低收入成人饮食质量相关的社会人口统计学和行为因素

IF 2.3 4区医学

Primary Care Diabetes Pub Date : 2026-02-01 Epub Date: 2025-11-26 DOI: 10.1016/j.pcd.2025.11.008

Kristine D. Gu , Daniel Shinnick , Tanayott Thaweethai , Jessica Cheng , Deborah J. Wexler , Anne N. Thorndike

{"title":"Sociodemographic and behavioral factors associated with diet quality in low-income adults with prediabetes and type 2 diabetes","authors":"Kristine D. Gu , Daniel Shinnick , Tanayott Thaweethai , Jessica Cheng , Deborah J. Wexler , Anne N. Thorndike","doi":"10.1016/j.pcd.2025.11.008","DOIUrl":"10.1016/j.pcd.2025.11.008","url":null,"abstract":"<div><h3>Aims</h3><div>Low-income adults face barriers to diabetes prevention and self-management, especially healthy eating. This study assessed factors associated with diet quality in low-income adults with prediabetes or type 2 diabetes (T2D), particularly modifiable factors that could be targeted in diabetes self-management education and support (DSMES).</div></div><div><h3>Methods</h3><div>This secondary analysis of a cohort of low-income health center patients in Boston, Massachusetts determined the association between diet quality and sociodemographic (e.g., race/ethnicity, social support) and behavioral (e.g., depression) factors in adults with prediabetes or T2D. Primary outcome was Healthy Eating Index-2020 (HEI; range 0–100, higher=healthier). Random forests, interpreted using Shapley Additive Explanation values, were fit to determine relative importance of factors in predicting HEI.</div></div><div><h3>Results</h3><div>Of 278 participants, 42 % had prediabetes and 58 % had T2D. Median age (IQR) was 52 (43, 57); 58 % were Hispanic. Top factors associated with higher HEI were older age, female gender, and Hispanic ethnicity; other important factors were non-smoking, greater dietary variety, less time sitting, higher sleep quality, lower stress, more social support, and fewer depression symptoms.</div></div><div><h3>Conclusion</h3><div>Modifiable factors for low diet quality, such as dietary variety, social support, and stress, could be emphasized in diabetes prevention and DSMES programs tailored for low-income populations.</div></div>","PeriodicalId":48997,"journal":{"name":"Primary Care Diabetes","volume":"20 1","pages":"Pages 120-126"},"PeriodicalIF":2.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145644188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on ‘Non-insulin-based markers of insulin resistance at diabetes diagnosis: A pooled analysis of 14 national health surveys’ 对《糖尿病诊断中胰岛素抵抗的非胰岛素基础标志物：对14个国家健康调查的汇总分析》的评论

IF 2.3 4区医学

Primary Care Diabetes Pub Date : 2026-02-01 Epub Date: 2025-12-05 DOI: 10.1016/j.pcd.2025.11.010

Long Pu

{"title":"Comment on ‘Non-insulin-based markers of insulin resistance at diabetes diagnosis: A pooled analysis of 14 national health surveys’","authors":"Long Pu","doi":"10.1016/j.pcd.2025.11.010","DOIUrl":"10.1016/j.pcd.2025.11.010","url":null,"abstract":"<div><div>This commentary provides methodological reflections on a recent multi-country study investigating insulin resistance (IR) marker heterogeneity in adults newly diagnosed with diabetes across 14 low and middle-income countries (LMICs). While commending the significant contribution of this research, we highlight three key considerations to refine the interpretation of findings and guide future studies. First, we discuss the need for population-specific validation of non-insulin-based IR markers, as their performance varies substantially across ethnic groups. Second, we examine the implications of relying on a single fasting glucose measurement for diabetes diagnosis, which may impact phenotypic characterization and subtype differentiation. Finally, we explore the importance of quantifying the relative contributions of multi-level factors—including adiposity, lifestyle, and healthcare system variables—to better understand the observed cross-country heterogeneity. Addressing these methodological aspects in future research will strengthen the evidence base for developing tailored diabetes care strategies in diverse global populations.</div></div>","PeriodicalId":48997,"journal":{"name":"Primary Care Diabetes","volume":"20 1","pages":"Page 145"},"PeriodicalIF":2.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145688779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mental health, substance abuse, and diabetes in low-income populations: A call for targeted research 低收入人群的心理健康、药物滥用和糖尿病：呼吁进行针对性研究。

IF 2.3 4区医学

Primary Care Diabetes Pub Date : 2026-02-01 Epub Date: 2025-11-06 DOI: 10.1016/j.pcd.2025.10.009

Syeda Shajia Shahid Gillani, Zainab Binte Tahir, Mahrosh Iftikhar, Zenia Safwan

引用次数: 0

Editorial Board and Aims & Scopes 编辑委员会和目标与范围

IF 2.3 4区医学

Primary Care Diabetes Pub Date : 2026-02-01 Epub Date: 2026-02-02 DOI: 10.1016/S1751-9918(26)00010-0

引用次数: 0

Impact of real-time continuous glucose monitoring and personalized digital health coaching on glycemic control and lifestyle in patients with type 2 diabetes and prediabetes 实时连续血糖监测和个性化数字健康指导对2型糖尿病及前驱糖尿病患者血糖控制和生活方式的影响

IF 2.3 4区医学

Primary Care Diabetes Pub Date : 2026-02-01 Epub Date: 2025-12-13 DOI: 10.1016/j.pcd.2025.12.002

Yujin Park , Hye Rin Choi , Ji-eun Lee , Boram Choi , Chang-bo Noh , Jae-Heon Kang , Ye Seul Bae

{"title":"Impact of real-time continuous glucose monitoring and personalized digital health coaching on glycemic control and lifestyle in patients with type 2 diabetes and prediabetes","authors":"Yujin Park , Hye Rin Choi , Ji-eun Lee , Boram Choi , Chang-bo Noh , Jae-Heon Kang , Ye Seul Bae","doi":"10.1016/j.pcd.2025.12.002","DOIUrl":"10.1016/j.pcd.2025.12.002","url":null,"abstract":"<div><h3>Objective</h3><div>This study evaluated the impact of real-time continuous glucose monitoring (CGM) combined with personalized digital health coaching on glycemic control and lifestyle behaviors in individuals with type 2 diabetes (T2DM) and prediabetes.</div></div><div><h3>Method</h3><div>A prospective cohort study was conducted involving 110 participants recruited from a chronic disease management service. The participants underwent an 8-week intervention where CGM data were used to provide real-time feedback, complemented by personalized lifestyle coaching. Baseline and post-intervention data included fasting blood glucose (FBG), glycated hemoglobin (HbA1c), body mass index (BMI), and lifestyle factors such as physical activity and eating habits. Participants were divided into tertiles based on mean amplitude of glycemic excursion (MAGE) to evaluate the effects of the intervention by glycemic variability (GV) level.</div></div><div><h3>Results</h3><div>Significant improvements in glycemic control were observed across all tertiles. The highest GV group (T3) showed the greatest reductions in HbA1c (7.39 % to 6.82 %, p = 0.004) and FBG. The physical activity scores significantly increased in the T3 group (p = 0.005), and all tertiles reported healthier dietary habits following the intervention.</div></div><div><h3>Conclusions</h3><div>The integration of CGM with personalized digital health coaching was associated with significant short-term improvements in glycemic control and lifestyle behaviors, particularly among individuals with high GV.</div></div>","PeriodicalId":48997,"journal":{"name":"Primary Care Diabetes","volume":"20 1","pages":"Pages 61-67"},"PeriodicalIF":2.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145752347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Glycemic status and effect on mortality: Multifactorial prevention programme for cardiovascular disease in Finnish primary care 血糖状态及其对死亡率的影响：芬兰初级保健心血管疾病的多因素预防方案。

IF 2.3 4区医学

Primary Care Diabetes Pub Date : 2026-02-01 Epub Date: 2025-11-07 DOI: 10.1016/j.pcd.2025.11.001

Zhipeng Dou, Lele Peng

引用次数: 0

Impact of frailty on foot care behaviors and self-efficacy in middle-aged and older adults with type 2 diabetes 虚弱对中老年2型糖尿病患者足部护理行为和自我效能的影响

IF 2.3 4区医学

Primary Care Diabetes Pub Date : 2026-02-01 Epub Date: 2025-11-21 DOI: 10.1016/j.pcd.2025.11.009

Döndü Bilici , Meryem Kılıç

{"title":"Impact of frailty on foot care behaviors and self-efficacy in middle-aged and older adults with type 2 diabetes","authors":"Döndü Bilici , Meryem Kılıç","doi":"10.1016/j.pcd.2025.11.009","DOIUrl":"10.1016/j.pcd.2025.11.009","url":null,"abstract":"<div><h3>Background</h3><div>Frailty is increasingly recognized as a condition that negatively affects self-management in individuals with type 2 diabetes. Limited evidence exists regarding its impact on diabetic foot self-care and self-efficacy, particularly in middle-aged populations.</div></div><div><h3>Objectives</h3><div>This study aimed to examine the effect of frailty on foot care behaviors and self-efficacy among middle-aged and older adults with type 2 diabetes.</div></div><div><h3>Methods</h3><div>A descriptive, cross-sectional study was conducted with 75 middle-aged (40–64 years) and 75 older (≥65 years) adults diagnosed with type 2 diabetes. Data were collected using the FRAIL Scale, the Foot Care Behavior Scale, and the Diabetic Foot Care Self-Efficacy Scale. Group comparisons were performed using independent t-tests, and regression analyses were used to evaluate the predictive role of frailty.</div></div><div><h3>Results</h3><div>Frailty prevalence was 22.7 % in middle-aged adults and 42.7 % in older adults. Regression analyses showed that frailty was a strong predictor of both self-efficacy and foot care behaviors. Each one-point increase in frailty score was associated with a ∼12-point decrease in self-efficacy (β=-0.876; p < 0.001) and an ∼8-point decrease in foot care behaviors (β=-0.905; p < 0.001). The explanatory power of frailty was greater in middle-aged adults compared to older adults.</div></div><div><h3>Conclusion</h3><div>Frailty significantly impairs foot care behaviors and self-efficacy in adults with type 2 diabetes. Routine frailty screening, even from middle age, may support the early identification of individuals at risk for diabetic foot complications and inform preventive wound care strategies.</div></div>","PeriodicalId":48997,"journal":{"name":"Primary Care Diabetes","volume":"20 1","pages":"Pages 115-119"},"PeriodicalIF":2.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145582496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Type 2 diabetes monitoring and control in migrants and non-migrants: A population-based cohort study in primary care in the Netherlands 移民和非移民的2型糖尿病监测和控制：荷兰一项基于人群的初级保健队列研究

IF 2.3 4区医学

Primary Care Diabetes Pub Date : 2026-02-01 Epub Date: 2025-10-15 DOI: 10.1016/j.pcd.2025.10.003

B.T. Strooij , S. Remmelzwaal , M. Muilwijk , J.A. Overbeek , R.M.C. Herings , P.J.M. Elders , H.P.J. van Hout , O.R. Maarsingh , I.G.M. van Valkengoed , M.T. Blom

{"title":"Type 2 diabetes monitoring and control in migrants and non-migrants: A population-based cohort study in primary care in the Netherlands","authors":"B.T. Strooij , S. Remmelzwaal , M. Muilwijk , J.A. Overbeek , R.M.C. Herings , P.J.M. Elders , H.P.J. van Hout , O.R. Maarsingh , I.G.M. van Valkengoed , M.T. Blom","doi":"10.1016/j.pcd.2025.10.003","DOIUrl":"10.1016/j.pcd.2025.10.003","url":null,"abstract":"<div><h3>Aims</h3><div>Type 2 diabetes (T2D) disproportionally affects migrants. We compared T2D-care in primary care between migrants and non-migrants in the Netherlands.</div></div><div><h3>Methods</h3><div>We performed a dynamic cohort study based on routine care data (2015–2019) from the DIAbetes MANagement and Treatment (DIAMANT) cohort linked to databases of Statistics Netherlands. Persons aged ≥ 35years with T2D treated in primary care were included. Outcomes included annual monitoring of HbA1c, systolic blood pressure and LDL; meeting of treatment targets; and medication prescription. Generalized estimating equations logistic regression models estimated the associations between having a migration background and outcomes.</div></div><div><h3>Results</h3><div>We included 165,670 persons: 83.7 % non-migrants, 2.1 % Turkish, 3.0 % Moroccan, 2.1 % Surinamese, 3.3 % European, and 5.7 % other non-European migrants. Most migrant groups had similar or higher odds of having annual monitoring compared to non-migrants, but lower odds of meeting the HbA1c and LDL treatment targets, with the lowest odds for Turkish migrants (OR 0.61, 95 %-CI 0.57–0.64; OR 0.86, 95 %-CI 0.81–0.91). Exploratory analyses demonstrated insulins to be less often prescribed to migrants.</div></div><div><h3>Conclusions</h3><div>Most migrant groups were equally or better monitored for T2D-parameters compared to non-migrants, but were less likely to meet HbA1c targets. This might partly reflect the less frequent insulin prescriptions to migrants. Further research is needed on underlying mechanisms and the specific needs of migrant groups to optimize T2D-care for all.</div></div>","PeriodicalId":48997,"journal":{"name":"Primary Care Diabetes","volume":"20 1","pages":"Pages 53-60"},"PeriodicalIF":2.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145310542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Continuous glucose monitoring patterns among pregnant individuals with varying levels of glucose intolerance 不同程度葡萄糖耐受不良孕妇的连续血糖监测模式

IF 2.3 4区医学

Primary Care Diabetes Pub Date : 2026-02-01 Epub Date: 2025-12-03 DOI: 10.1016/j.pcd.2025.11.006

Rachel D. Gordon , Jiqiang Wu , Jennifer Grasch , Neeharika Nandam , Patrick Schneider , Steven Gabbe , Mark B. Landon , Maged M. Costantine , Kartik K. Venkatesh , Elizabeth O. Buschur

引用次数: 0