Brazilian Oral Research最新文献_第3页

Impact of COVID-19 pandemic on completed treatments and referrals during urgent dental visits. COVID-19大流行对完成治疗和紧急牙科就诊期间转诊的影响。

IF 2.5 4区医学

Brazilian Oral Research Pub Date : 2023-01-01 DOI: 10.1590/1807-3107bor-2023.vol37.0087

Luciéli Andréia Zajkowski, Roberta Kochenborger Scarparo, Heloisa Grehs E Silva, Roger Keller Celeste, Patrícia Maria Poli Kopper

{"title":"Impact of COVID-19 pandemic on completed treatments and referrals during urgent dental visits.","authors":"Luciéli Andréia Zajkowski, Roberta Kochenborger Scarparo, Heloisa Grehs E Silva, Roger Keller Celeste, Patrícia Maria Poli Kopper","doi":"10.1590/1807-3107bor-2023.vol37.0087","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2023.vol37.0087","url":null,"abstract":"This ecological study assessed the impact of the COVID-19 pandemic on completed treatments (CTs) and referrals during urgent dental visits to primary health care units in Brazil, and their associations with socioeconomic, geodemographic, and pandemic index factors in Brazilian municipalities. The difference in rates of procedures 12 months before and during the pandemic was calculated. Data were extracted at baseline from health information systems of all municipalities that provided urgent dental care (n = 5,229 out of 5,570). Multiple logistic regression predicted the factors associated with referrals and CTs. The number of dental urgencies increased from 3,987.9 to 4,272.4 per 100,000 inhabitants. The rates of referrals decreased in 44.1% of the municipalities, while 53.9% had lower rates of CTs. Municipalities with a greater number of oral health teams in the primary health care system (OR = 1.52, 95%CI:1.21-1.91) and with specialized services (OR = 1.80, 95%CI:1.50-2.16) were more likely to decrease referrals during the pandemic. Higher HDI and GDP per capita were associated with a larger decrease in referrals and smaller decrease in CTs. The calamity generated by the long pandemic period resulted in a greater demand for urgent visits. Less developed and larger cities seem to have been more likely to not complete treatments during urgent visits in primary dental care units in times of calamity. Primary dental care offices in smaller and less developed municipalities should be better equipped to provide appropriate assistance and to improve the problem-solving capacity of dental services during emergencies.","PeriodicalId":48942,"journal":{"name":"Brazilian Oral Research","volume":"37 ","pages":"e087"},"PeriodicalIF":2.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10180823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dental anomalies in syndromes displaying hypertrichosis in the clinical spectrum. 临床表现多毛综合征的牙齿异常。

IF 2.5 4区医学

Brazilian Oral Research Pub Date : 2023-01-01 DOI: 10.1590/1807-3107bor-2023.vol37.0030

Vinícius Figueiredo Carneiro, Renato Assis Machado, Mauro Costa Barbosa, Verônica Oliveira Dias, Daniella Reis Barbosa Martelli, Hercílio Martelli-Júnior

{"title":"Dental anomalies in syndromes displaying hypertrichosis in the clinical spectrum.","authors":"Vinícius Figueiredo Carneiro, Renato Assis Machado, Mauro Costa Barbosa, Verônica Oliveira Dias, Daniella Reis Barbosa Martelli, Hercílio Martelli-Júnior","doi":"10.1590/1807-3107bor-2023.vol37.0030","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2023.vol37.0030","url":null,"abstract":"Hypertrichosis and dental anomalies may occur alone or in combination in the spectrum of many syndromes. To identify genetic entities characterized by hypertrichosis and dental anomalies, a search was performed in the Mendelian Inheritance in Man database with the terms \"hypertrichosis\" or \"hirsutism\" and \"tooth\" or \"dental abnormalities.\" Nondependent androgen metabolism disturbances were classified as hypertrichosis. Genetic entities with hypertrichosis and dental anomalies were included in the study. Additional searches were performed in the PubMed and Orphanet databases, when necessary, in order to include data from scientific articles. An integrative analysis of the genes associated with the identified syndromes was conducted using STRING to characterize biological processes, pathways, and interactive networks. The p-values were subjected to the false discovery rate for the correction of multiple tests. Thirty-nine syndromes were identified, and dental agenesis was the most frequent dental anomaly present in 41.02% (n = 16) of the syndromes. Causative genes were identified in 33 out of 39 genetic syndromes. Among them, 39 genes were identified, and 38 were analyzed by STRING, which showed 148 biological processes and three pathways that were statistically significant. The most significant biological processes were the disassembly of the nucleosome (GO:0006337, p = 1.09e-06), chromosomal organization (GO:0051276, p = 1.09e-06) and remodeling of the chromatin (GO: 0006338, p = 7.86e-06), and the pathways were hepatocellular carcinoma (hsa05225, p = 5.77e-05), thermogenesis (hsa04714, p = 0.00019), and cell cycle (hsa04110, p = 0.0433). Our results showed that the identification of hypertrichosis and dental anomalies may raise the suspicion of one of the thirty-nine syndromes with both phenotypes.","PeriodicalId":48942,"journal":{"name":"Brazilian Oral Research","volume":"37 ","pages":"e030"},"PeriodicalIF":2.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9257121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of access cavities on root canal preparation, restorative protocol quality, and fracture resistance of teeth 通道腔对根管预备、修复方案质量和牙齿抗折性的影响

4区医学

Brazilian Oral Research Pub Date : 2023-01-01 DOI: 10.1590/1807-3107bor-2023.vol37.0096

Heitor Silva PRADO, Igor Bassi Ferreira PETEAN, Natália Junqueira Saud FRANCO, Rafael Verardino CAMARGO, Kleber Kildare Teodoro de CARVALHO, Jardel Francisco MAZZI-CHAVES, Fabiane Carneiro LOPES-OLHÊ, Yara Teresinha Corrêa SILVA-SOUSA, Aline Evangelista SOUZA-GABRIEL, Manoel Damião SOUSA-NETO

{"title":"Impact of access cavities on root canal preparation, restorative protocol quality, and fracture resistance of teeth","authors":"Heitor Silva PRADO, Igor Bassi Ferreira PETEAN, Natália Junqueira Saud FRANCO, Rafael Verardino CAMARGO, Kleber Kildare Teodoro de CARVALHO, Jardel Francisco MAZZI-CHAVES, Fabiane Carneiro LOPES-OLHÊ, Yara Teresinha Corrêa SILVA-SOUSA, Aline Evangelista SOUZA-GABRIEL, Manoel Damião SOUSA-NETO","doi":"10.1590/1807-3107bor-2023.vol37.0096","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2023.vol37.0096","url":null,"abstract":"The survival of endodontically treated teeth depends on the remaining tooth structure. The aim of this study was to evaluate the impact of different access cavities on root canal preparation, restorative protocol, and fracture resistance of endodontically treated teeth. Fifty-six mandibular molars were divided into control (n=8) and experimental (n=16) groups according to access cavity: Traditional, Conservative, and Truss; and redistributed (n=8) according to instrumentation protocols: Reciproc Blue and R-motion. After, teeth were scanned in micro-CT and then filled and redistributed according to composite resin restoration (n=8): Filtek One BulkFill and Filtek Z350. A new micro-CT scan was performed to analyze the restorative material. Then, samples were submitted to fracture resistance testing and the failure pattern was determined. Data were analyzed using paired T-test, ANOVA, Tukey, and chi-square tests (α=0.05). In Truss, R-Motion promoted less transportation in different thirds of root canals. Higher percentages of voids (5.05%) and filling material (11.7%) were observed in Truss. Fracture resistance values were higher for the control group, followed by Truss, Conservative, and Traditional. The predominant failure pattern was type-II. In Truss, reciprocating instruments with smaller taper showed less canal transportation. Also, Truss provided higher values of fracture resistance, although it presented a higher percentage of voids and remaining filling material. Thus, in Truss, reciprocating files with smaller taper showed less canal transportation, and these cavities provided higher values of fracture resistance, although it presented a higher percentage of voids and remaining filling material.","PeriodicalId":48942,"journal":{"name":"Brazilian Oral Research","volume":"122 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135213371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID-19 and changes in dental practices in the Brazilian Public Health System: perception of the oral health team COVID-19与巴西公共卫生系统牙科实践的变化:对口腔卫生团队的看法

4区医学

Brazilian Oral Research Pub Date : 2023-01-01 DOI: 10.1590/1807-3107bor-2023.vol37.0117

Suzely Adas Saliba MOIMAZ, Carolina Carvalho Menez Pinto NASCIMENTO, Tânia Adas SALIBA, Cléa Adas Saliba GARBIN, Nemre Adas SALIBA

{"title":"COVID-19 and changes in dental practices in the Brazilian Public Health System: perception of the oral health team","authors":"Suzely Adas Saliba MOIMAZ, Carolina Carvalho Menez Pinto NASCIMENTO, Tânia Adas SALIBA, Cléa Adas Saliba GARBIN, Nemre Adas SALIBA","doi":"10.1590/1807-3107bor-2023.vol37.0117","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2023.vol37.0117","url":null,"abstract":"The aim of this study was to verify the perception of the oral health team regarding work safety and aspects related to changes in dental practices during the COVID-19 pandemic. A descriptive, exploratory, quantitative, and qualitative cross-sectional study was conducted using an electronic questionnaire sent via email to health professionals (n = 197) affiliated with the Brazilian Public Health System (SUS), from December 2020 to September 2021, in a municipality located in the northeast of the state of São Paulo, Brazil. The variables of interest were sociodemographic characteristics and those related to the professionals’ perception of oral health care during the pandemic and its impact on these workers’ occupational safety. Descriptive statistics were performed, and the absolute and relative frequencies of quantitative variables were calculated, whereas lexical analysis was performed for textual content using the descending hierarchical classification (CHD). Out of the total sample, elective and urgent/emergency care was provided by 58.95% (n = 56); physical barriers were absent between the teams in 54.74% (n = 52); minimally invasive techniques were applied in 71.58% (n = 68); personal protective equipment (PPE) was replaced in 81.05% (n = 77) between appointments; and occupational safety was reported by 49.47% (n = 47). Textual analysis showed a decrease in appointments and consultations, with a longer interval between appointments. The professionals noticed changes in dental practices during the pandemic, mainly regarding the use of PPE, the type of treatment performed, the number of treated patients, and the greater time interval between consultations. The physical infrastructure of health units and the availability of PPE to patients needed some adjustments. A significant number of workers felt safe in providing dental care during the pandemic.","PeriodicalId":48942,"journal":{"name":"Brazilian Oral Research","volume":"136 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135611925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clarity of publications on HPV in Instagram profiles of official health agencies in Brazil 巴西官方卫生机构Instagram资料中关于HPV的出版物的清晰度

4区医学

Brazilian Oral Research Pub Date : 2023-01-01 DOI: 10.1590/1807-3107bor-2023.vol37.0103

Wanúbia Barbosa NUNES, Ramon Targino FIRMINO, Angélica Maria Cupertino Lopes MARINHO, Lílian de Sá BARRETO, Myrelle Leal Campos SOUSA, Samara Ellen da SILVA, Edja Maria Melo de Brito COSTA, Matheus França PERAZZO, Ana Flávia GRANVILLE-GARCIA

{"title":"Clarity of publications on HPV in Instagram profiles of official health agencies in Brazil","authors":"Wanúbia Barbosa NUNES, Ramon Targino FIRMINO, Angélica Maria Cupertino Lopes MARINHO, Lílian de Sá BARRETO, Myrelle Leal Campos SOUSA, Samara Ellen da SILVA, Edja Maria Melo de Brito COSTA, Matheus França PERAZZO, Ana Flávia GRANVILLE-GARCIA","doi":"10.1590/1807-3107bor-2023.vol37.0103","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2023.vol37.0103","url":null,"abstract":"The study analyzed the clarity of publications on human papillomavirus (HPV) in the Instagram profiles of official Brazilian health agencies. An infodemiological study analyzed publications on HPV in the 81 Instagram profiles selected from the Health Ministry, States' Health Departments, and dental councils and associations. The following data were collected: classification of content, type of profiles, type of media, how the content was addressed, number of posts, frequency, likes, comments, viewings, and hashtags, and how the HPV vaccine was addressed. The clarity of the educational publications was assessed using the Brazilian version of the Clear Communication Index (BR-CDC-CCI). Data analysis was performed with Spearman's correlation and the Mann-Whitney test (p < 0.05). A total of 504 publications on HPV were found. The average number of likes was 528.3 (SD = 2388.2) and the average BR-CDC-CCI score was 67.1 (SD = 14.1). The quality and clarity of the information was considered adequate (BR-CDC-CCI score ≥ 90) in 6.9% of the publications. A weak positive correlation was found between the number of likes and both the BR-CDC-CCI score (r = 0.195) and number of posts (r = 0.124). Publications from the Health Ministry had a significantly higher BR-CDC-CCI score (72.9) compared to the other profiles analyzed (p = 0.01). Most publications concerned government actions, had low engagement, and written educational information was of low clarity and quality. However, the effort to reach the population was evident, with an increase in publications over the years.","PeriodicalId":48942,"journal":{"name":"Brazilian Oral Research","volume":"133 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134883848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Does resveratrol favor peri-implant bone repair in rats with ovariectomy-induced osteoporosis? Gene expression, counter-torque and micro-CT analysis. 白藜芦醇是否有利于卵巢切除术所致骨质疏松大鼠种植体周围骨修复?基因表达，反扭矩和微ct分析。

IF 2.5 4区医学

Brazilian Oral Research Pub Date : 2023-01-01 DOI: 10.1590/1807-3107bor-2023.vol37.0003

Rodrigo Soler Zamai, Monica Grazieli Corrêa, Fernanda Vieira Ribeiro, Fabiano Ribeiro Cirano, Marcio Zaffalon Casati, Michel Reis Messora, Suzana Peres Pimentel

{"title":"Does resveratrol favor peri-implant bone repair in rats with ovariectomy-induced osteoporosis? Gene expression, counter-torque and micro-CT analysis.","authors":"Rodrigo Soler Zamai, Monica Grazieli Corrêa, Fernanda Vieira Ribeiro, Fabiano Ribeiro Cirano, Marcio Zaffalon Casati, Michel Reis Messora, Suzana Peres Pimentel","doi":"10.1590/1807-3107bor-2023.vol37.0003","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2023.vol37.0003","url":null,"abstract":"This study investigated the influence of resveratrol on peri-implant repair and its effects on bone-related markers in ovariectomy-induced osteoporosis in rats. Animals were divided into: OVX+PLAC (n = 10): ovariectomized animals treated with placebo; OVX+RESV (n = 10): OVX treated with resveratrol; OVX+PLAC+ZOL (n = 10): OVX treated with PLAC and zoledronate; OVX+RESV+ZOL (n = 10): OVX treated with RESV and ZOL; and SHOVX+PLAC (n = 10): sham ovariectomy treated with PLAC. RESV and PLAC were administrated after ovariectomy and ZOL after six weeks after OVX, until the end of experiment. One implant was inserted in each tibiae of animals 18 weeks after ovariectomy. After 4 weeks, one implant was removed for counter-torque, and peri-implant tissue was collected for mRNA quantification of several osteogenic markers by PCR. The other tibia was submitted to micro-computed tomography analysis. Reduced counter-torque values, bone-implant contact (BIC) and bone volume fraction (BV/TV), and higher bone porosity (BP) were detected in OVX+PLAC group when compared to SHOVX+PLAC (p < 0.05). OVX+RESV rats presented lower BIC, BV/TV, and trabecular number (Tb.N), and augmented BP and trabecular spacing (Tb.Sp) when compared to SHOVX+PLAC (p < 0.05). Higher Tb.N and connectivity density (Conn.Dn) and reduced Tb.Sp were observed in OVX rats treated with ZOL, independently of RESV, when compared to OVX+PLAC and OVX+RESV groups (p < 0.05), whereas the combination ZOL+RESV promoted lower BP when compared to OVT+PLAC and OVX+RESV (p < 0.05). Gene expression was not influenced by RESV (p > 0.05), whereas ZOL promoted up-regulation of BMP-2 (p<0.05). RESV did not improve peri-implant bone repair in rats with ovariectomy-induced osteoporosis.","PeriodicalId":48942,"journal":{"name":"Brazilian Oral Research","volume":"37 ","pages":"e003"},"PeriodicalIF":2.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9149230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Effect of dentin moisture on the adhesive properties of luting fiber posts using adhesive strategies. 牙本质水分对丝路纤维桩粘接性能的影响。

IF 2.5 4区医学

Brazilian Oral Research Pub Date : 2023-01-01 DOI: 10.1590/1807-3107bor-2023.vol37.0042

Renata Terumi Jitumori, Rafaela Caroline Rodrigues, Alessandra Reis, João Carlos Gomes, Giovana Mongruel Gomes

{"title":"Effect of dentin moisture on the adhesive properties of luting fiber posts using adhesive strategies.","authors":"Renata Terumi Jitumori, Rafaela Caroline Rodrigues, Alessandra Reis, João Carlos Gomes, Giovana Mongruel Gomes","doi":"10.1590/1807-3107bor-2023.vol37.0042","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2023.vol37.0042","url":null,"abstract":"The purpose of this study was to evaluate the effect of dentin moisture (moist and dry) on the bonding of fiber posts to root dentin with different adhesive strategies (etch-and-rinse, self-etch, and self-adhesive). Seventy-two extracted single-rooted human teeth were endodontically treated and divided into six groups (n = 12) according to the moisture of dentin surface and adhesive systems as follows: a) etch-and-rinse/moist, b) etch-and-rinse/dry, c) self-etch/moist, d) self-etch/dry, e) self-adhesive/moist, and 6) self-adhesive/dry. The specimens were sectioned into six slices for push-out bond strength (BS), nanoleakage (NL) by SEM, and Vickers microhardness (VHN) of the resin cement. A universal testing machine (AG-I, Shimadzu Autograph) was used at a crosshead speed of 0.5 mm/min until post extrusion, with a load cell of 50 kg for evaluation of the push-out strength. Data on BS, NL, and VHN were evaluated by two-way ANOVA and Tukey's test (α = 0.05). Dentin moisture as the main factor was not significantly different for the push-out test. However, higher BS values can be observed for the etch-and-rinse group. A lower percentage of NL was found in the dry dentin groups. The moisture pattern was not significant in the hardness values for the pre-etching groups. Additional moisture did not increase the evaluated properties.","PeriodicalId":48942,"journal":{"name":"Brazilian Oral Research","volume":"37 ","pages":"e42"},"PeriodicalIF":2.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9773962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Translation and cultural adaptation of the Illness Perception Questionnaire-Revised for Dental to Brazil. 疾病感知问卷的翻译和文化适应-为巴西牙科修订。

IF 2.5 4区医学

Brazilian Oral Research Pub Date : 2023-01-01 DOI: 10.1590/1807-3107bor-2023.vol37.0004

Marjorie Izabella Batista Aguiar, Bruna Letícia Basso, Marília Leão Goettems, Marina Sousa Azevedo, Vanessa Polina Pereira da Costa, Renata Andréa Salvitti de Sá Rocha, Maria Beatriz Duarte Gavião, Taís de Souza Barbosa

{"title":"Translation and cultural adaptation of the Illness Perception Questionnaire-Revised for Dental to Brazil.","authors":"Marjorie Izabella Batista Aguiar, Bruna Letícia Basso, Marília Leão Goettems, Marina Sousa Azevedo, Vanessa Polina Pereira da Costa, Renata Andréa Salvitti de Sá Rocha, Maria Beatriz Duarte Gavião, Taís de Souza Barbosa","doi":"10.1590/1807-3107bor-2023.vol37.0004","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2023.vol37.0004","url":null,"abstract":"This study aimed to translate and to perform the cultural adaptation of the instrument Illness Perception Questionnaire-Revised for Dental (IPQ-RD) into Brazilian Portuguese. The IPQ-RD consists of 34 items that assess the cognitive and emotional representation/perception of parents/caregivers of children with dental caries, with response options on a 5-point Likert scale, ranging from \"Strongly agree\" (score 1) to \"Strongly disagree\" (score 5). The higher the score, the lower the perception of the disease. The protocol consists of translation into Brazilian Portuguese, back-translation into English, revision by an Expert Review Committee, and pre-test (application in parents/caregivers of children in dental care). For some questions, the translated versions were identical (T1 = T2); for others, one version was preferred (T1 or T2); for still others, it was decided to modify terms to obtain greater clarity on the item (T3). In the first pre-test, three questions were misunderstood by more than 15% of the sample, after which the items were reviewed by the Expert Review Committee. In the second pre-test, the adapted version was applied to a new sample of parents/caregivers (n = 15) and the questions were understood by more than 85% of the participants. The Brazilian Portuguese version of the IPQ-RD was well understood by the evaluated population.","PeriodicalId":48942,"journal":{"name":"Brazilian Oral Research","volume":"37 ","pages":"e004"},"PeriodicalIF":2.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10608824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synchronous jawbone diseases: a multicenter retrospective study. 同步颌骨疾病:一项多中心回顾性研究。

IF 2.5 4区医学

Brazilian Oral Research Pub Date : 2023-01-01 DOI: 10.1590/1807-3107bor-2023.vol37.0011

Diogo Dos Santos da Mata Rezende, Lucas Lacerda de Souza, Daniel Cavalléro Colares Uchôa, Lais Albuquerque Fernandes, Jeanne Gisele Rodrigues de Lemos, Alan Roger Santos-Silva, Márcio Ajudarte Lopes, Lady Paola Aristizabal Arboleda, André Caroli Rocha, Fábio Luiz Neves Gonçalves, Flávia Sirotheau Corrêa Pontes, Felipe Paiva Fonseca, Hélder Antônio Rebelo Pontes

{"title":"Synchronous jawbone diseases: a multicenter retrospective study.","authors":"Diogo Dos Santos da Mata Rezende, Lucas Lacerda de Souza, Daniel Cavalléro Colares Uchôa, Lais Albuquerque Fernandes, Jeanne Gisele Rodrigues de Lemos, Alan Roger Santos-Silva, Márcio Ajudarte Lopes, Lady Paola Aristizabal Arboleda, André Caroli Rocha, Fábio Luiz Neves Gonçalves, Flávia Sirotheau Corrêa Pontes, Felipe Paiva Fonseca, Hélder Antônio Rebelo Pontes","doi":"10.1590/1807-3107bor-2023.vol37.0011","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2023.vol37.0011","url":null,"abstract":"The aim of this study is to report an original case series of synchronous jawbone diseases. Data of patients seen over 13 years were extracted from the files of three Oral Radiology and Pathology diagnostic centers in Brazil. The clinical, radiographic, and laboratory characteristics were tabulated and analyzed by the authors; the patients were described according to lesion type. Seventy-two synchronous jawbone diseases were included in this study. Florid osseous dysplasia, Gorlin-Goltz syndrome, and cherubism were the most frequent disorders reported in this case series. In addition, the posterior mandible area was the main site of manifestation. Florid osseous dysplasia and Gorlin-Goltz syndrome represented two-thirds of our samples. With the utilization of adequate demographic, clinical, and radiologic information, it is possible to diagnose most of the synchronous lesions of jawbones. Sometimes, however, we need complementary exams, such as histopathologic and biochemical analysis or dosing of calcium, phosphorus, and alkaline phosphatase.","PeriodicalId":48942,"journal":{"name":"Brazilian Oral Research","volume":"37 ","pages":"e011"},"PeriodicalIF":2.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10727463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protease-activated receptor type 2 activation downregulates osteogenesis in periodontal ligament stem cells. 蛋白酶激活受体2型激活下调牙周韧带干细胞成骨。

IF 2.5 4区医学

Brazilian Oral Research Pub Date : 2023-01-01 DOI: 10.1590/1807-3107bor-2023.vol37.0002

Bruno Nunes de França, Letícia Miquelitto Gasparoni, Emanuel Silva Rovai, Lucas Macedo Batitucci Ambrósio, Nathalia Felix de Mendonça, Marcos Hideki Hagy, Aldrin Huamán Mendoza, Carla Renata Sipert, Marinella Holzhausen

{"title":"Protease-activated receptor type 2 activation downregulates osteogenesis in periodontal ligament stem cells.","authors":"Bruno Nunes de França, Letícia Miquelitto Gasparoni, Emanuel Silva Rovai, Lucas Macedo Batitucci Ambrósio, Nathalia Felix de Mendonça, Marcos Hideki Hagy, Aldrin Huamán Mendoza, Carla Renata Sipert, Marinella Holzhausen","doi":"10.1590/1807-3107bor-2023.vol37.0002","DOIUrl":"https://doi.org/10.1590/1807-3107bor-2023.vol37.0002","url":null,"abstract":"Protease-activated receptor-2 (PAR2) is associated with the pathogenesis of many chronic diseases with inflammatory characteristics, including periodontitis. This study aimed to evaluate how the activation of PAR2 can affect the osteogenic activity of human periodontal ligament stem cells (PDLSCs) in vitro. PDLSCs collected from three subjects were treated in osteogenic medium for 2, 7, 14, and 21 days with trypsin (0.1 U/mL), PAR2 specific agonist peptide (SLIGRL-NH2) (100 nM), and PAR2 antagonist peptide (FSLLRY-NH2) (100 nM). Gene (RT-qPCR) expression and protein expression (ELISA) of osteogenic factors, bone metabolism, and inflammatory cytokines, cell proliferation, alkaline phosphatase (ALP) activity, alizarin red S staining, and supernatant concentration were assessed. Statistical analysis of the results with a significance level of 5% was performed. Activation of PAR2 led to decreases in cell proliferation and calcium deposition (p < 0.05), calcium concentration (p < 0.05), and ALP activity (p < 0.05). Additionally, PAR2 activation increased gene and protein expression of receptor activator of nuclear factor kappa-Β ligand (RANKL) (p < 0.05) and significantly decreased the gene and protein expression of osteoprotegerin (p <0. 05). Considering the findings, the present study demonstrated PAR2 activation was able to decrease cell proliferation, decreased osteogenic activity of PDLSCs, and upregulated conditions for bone resorption. PAR2 may be considered a promising target in periodontal regenerative procedures.","PeriodicalId":48942,"journal":{"name":"Brazilian Oral Research","volume":"37 ","pages":"e002"},"PeriodicalIF":2.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9072163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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