Current Opinion in Supportive and Palliative Care最新文献_第7页

Cancer cachexia in thoracic malignancy: a narrative review. 胸部恶性肿瘤的癌症恶病质：叙述性综述。

IF 2.1 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2019-12-01 DOI: 10.1097/SPC.0000000000000465

Andrew C Kidd, Marcin Skrzypski, Mariam Jamal-Hanjani, Kevin G Blyth

{"title":"Cancer cachexia in thoracic malignancy: a narrative review.","authors":"Andrew C Kidd, Marcin Skrzypski, Mariam Jamal-Hanjani, Kevin G Blyth","doi":"10.1097/SPC.0000000000000465","DOIUrl":"10.1097/SPC.0000000000000465","url":null,"abstract":"Purpose of review: Thoracic malignancies are amongst the most lethal of all cancers. Cancer cachexia lacks unanimously accepted diagnostic criteria, and therefore is referenced to as a conceptual framework whereby cancer cachexia is 'an ongoing loss of skeletal muscle mass (termed sarcopenia), with or without loss of fat mass that cannot be reversed by conventional nutritional support and leads to progressive functional impairment'. This review summarises the current evidence base in this field, including imaging techniques currently used to define sarcopenia, inflammatory and metabolic changes associated with the syndrome and ongoing research into potential treatment strategies.Recent findings: Sarcopenia is a key component of the cancer cachexia syndrome. It is common in patients with both early-stage and advanced NSCLC. Patients with sarcopenia have more treatment-related side effects and poorer overall survival compared with nonsarcopenic patients.Summary: Early identification of cancer cachexia may facilitate stratification of patients most-at-risk and initiation of emerging anticachexia treatments. If these are proven to be effective, this strategy has the potential to improve tolerance to anti-cancer therapies, improving the quality of life, and perhaps the survival, of patients with thoracic malignancies.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87338296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cardiac cachexia: the mandate to increase clinician awareness. 心脏恶病质:提高临床医生意识的任务。

IF 2.1 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2019-12-01 DOI: 10.1097/SPC.0000000000000456

A. Lena, N. Ebner, A. Coats, M. Anker

引用次数: 11

What information and resources do carers require pre and post bereavement in the acute hospital setting? A rapid review. 在急性医院环境中，护理人员在丧亲前后需要哪些信息和资源?快速回顾。

IF 2.1 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2019-12-01 DOI: 10.1097/SPC.0000000000000462

Brenda Jackson, J. McPeake, B. Johnston

{"title":"What information and resources do carers require pre and post bereavement in the acute hospital setting? A rapid review.","authors":"Brenda Jackson, J. McPeake, B. Johnston","doi":"10.1097/SPC.0000000000000462","DOIUrl":"https://doi.org/10.1097/SPC.0000000000000462","url":null,"abstract":"PURPOSE OF REVIEW\u0000This mixed-method, rapid review of published research from 2014 to 2019 aims to explore the experiences of pre and postbereaved carers, and the information that they receive in the acute hospital setting. The quality of articles was evaluated using a standardized quality matrix. The techniques of conceptual analysis and idea mapping were used to create a structured synthesis of the findings.\u0000\u0000\u0000RECENT FINDINGS\u0000From the initial search of 432 articles, ten studies met the inclusion criteria for this review. These studies generated data from 42 patients, 1968 family/carers and 139 healthcare staff. Themes that were generated from a synthesis of the included articles were clear and timely communication, workforce provision and environment.\u0000\u0000\u0000SUMMARY\u0000This review has highlighted the need for improvements in information provision for carers as part of end of life care. Furthermore, the need for specific staff education and training to enable staff to confidently communicate with dying patients and their relatives in the acute setting is also warranted. Understanding and addressing gaps in knowledge and practice are essential to develop strategies in this complex area. Simple strategies can be implemented to improve the care of carers both pre and post bereavement in acute care.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80104041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Death rattle: reassuring harbinger of imminent death or a perfect example of inadequacies in evidence-based practice. 死亡颤音:死亡即将来临的令人安心的预兆，或者是循证实践不足的完美例子。

IF 2.1 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2019-12-01 DOI: 10.1097/SPC.0000000000000463

T. Watts, Derek Willis, S. Noble, B. Johnston

引用次数: 2

Endocrinopathies and cancer cachexia.

IF 2.1 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2019-12-01 DOI: 10.1097/SPC.0000000000000464

R. Dev, E. D. Del Fabbro, S. Dalal

{"title":"Endocrinopathies and cancer cachexia.","authors":"R. Dev, E. D. Del Fabbro, S. Dalal","doi":"10.1097/SPC.0000000000000464","DOIUrl":"https://doi.org/10.1097/SPC.0000000000000464","url":null,"abstract":"PURPOSE OF REVIEW\u0000Cancer cachexia cannot be easily reversed by standard nutritional support and interventions directed at underlying metabolic derangements may be needed to prevent or reverse cachexia and maintain healthy body composition. The following review will highlight the contribution and potential therapeutic interventions for insulin resistance, alterations in ghrelin signaling, and hypogonadism in cancer patients.\u0000\u0000\u0000RECENT FINDINGS\u0000In addition to decreased caloric intake, chronic inflammation, and altered metabolism of glucose, proteins and lipids, endocrine abnormalities can propagate weight loss or changes in body composition in cancer patients.\u0000\u0000\u0000SUMMARY\u0000Cancer cachexia, loss of muscle mass with or without the loss of fat mass, is a multifactorial syndrome, which is associated with increased morbidity and mortality. Currently, limited therapeutic options for the treatment of weight loss in cancer patients exist, which lead to clinically meaningful improvements in weight gain and performance status. Treatment directed at underlying insulin resistance, low testosterone, and altered ghrelin sensitivity, in the future, may lead to potential therapeutic options for loss of lean body mass and cancer cachexia.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88938114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Online couple interventions in cancer. 在线夫妻干预癌症。

IF 2.1 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2019-11-27 DOI: 10.1097/SPC.0000000000000476

R. Vanstone, K. Fergus

{"title":"Online couple interventions in cancer.","authors":"R. Vanstone, K. Fergus","doi":"10.1097/SPC.0000000000000476","DOIUrl":"https://doi.org/10.1097/SPC.0000000000000476","url":null,"abstract":"PURPOSE OF REVIEW\u0000Cancer diagnosis and treatment can have long-lasting psychological and physical consequences that affect both patients and their intimate partners. Improved understanding of extant dyadic interventions in the context of cancer, and how access to these may be enhanced through web-based technologies, introduce new directions for how cancer-related psychological distress for couples may be ameliorated.\u0000\u0000\u0000RECENT FINDINGS\u0000Couples are negatively impacted by cancer, both individually, and as a dyad. Bolstering techniques to support effective communication about common cancer-related concerns and support for adjusting to new roles and responsibilities may help to strengthen the couple's relationship so partners are better able to cope with cancer. Although there are various intervention options available for couples dealing with cancer, many pose barriers to participation because of constraints on time and/or distance. However, online interventions have been shown to be effective, both in easing psychological distress and reducing participant burden.\u0000\u0000\u0000SUMMARY\u0000Couples dealing with cancer experience psychological distress and must learn to navigate changing roles and responsibilities in the face of the disease. Online interventions offer flexible and innovative platforms and programs that help to address couples' educational needs while strengthening dyadic coping.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2019-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89888643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Online interventions for sexual health in cancer. 癌症性健康的在线干预。

IF 2.1 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2019-11-19 DOI: 10.1097/SPC.0000000000000477

A. Matthew, Zhiyong Yang

{"title":"Online interventions for sexual health in cancer.","authors":"A. Matthew, Zhiyong Yang","doi":"10.1097/SPC.0000000000000477","DOIUrl":"https://doi.org/10.1097/SPC.0000000000000477","url":null,"abstract":"PURPOSE OF REVIEW\u0000Recent advances in digital healthcare, combined with the increasing appreciation for the need for sexual health programming in cancer, has established a zeitgeist for further development of digital health interventions for sexual health in cancer. Developers of digital health interventions should consider two equally important factors: efficacy of the intervention, and participant engagement. This review describes the status of digital health interventions in sexual health within the oncology setting.\u0000\u0000\u0000RECENT FINDINGS\u0000Sexual dysfunction and related psychological distress affecting patients and their partners is recognized as a significant survivorship care need in the oncology setting. Provision of care is challenged by traditional approaches to disease follow-up, and limited healthcare resources. Digital health interventions may offer efficient, accessible, and scalable care pathways. Digital health innovation in cancer survivorship and sexual health indicates trends toward efficacy, yet patient engagement remains a challenge. Implementation of established online patient engagement approaches are recommended.\u0000\u0000\u0000SUMMARY\u0000Studies to date may underestimate the potential of digital health interventions in sexual health and cancer due to poor patient engagement. Developers of digital health intervention will benefit from effort in employing engagement strategies and engagement-efficacy analysis.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2019-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75614368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Spirituality in heart failure: a review of the literature from 2014 to 2019 to identify spiritual care needs and spiritual interventions. 心力衰竭的精神性:2014年至2019年的文献回顾，以确定精神护理需求和精神干预措施。

IF 2.1 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2019-11-12 DOI: 10.1097/SPC.0000000000000475

L. Ross, J. Miles

{"title":"Spirituality in heart failure: a review of the literature from 2014 to 2019 to identify spiritual care needs and spiritual interventions.","authors":"L. Ross, J. Miles","doi":"10.1097/SPC.0000000000000475","DOIUrl":"https://doi.org/10.1097/SPC.0000000000000475","url":null,"abstract":"PURPOSE OF REVIEW\u0000The burden of heart failure is significant and its management is complex. Current evidence confirms a high level of spiritual distress and a strong desire for spiritual support, which is endorsed by healthcare policy, yet spiritual support is rarely provided for this patient group. There is a need to identify how spiritual support might be meaningfully included within holistic heart failure multidisciplinary care and how its effectiveness might be demonstrated.\u0000\u0000\u0000RECENT FINDINGS\u0000A literature review was undertaken to identify recent evidence (2014-2019) of the spiritual care needs of heart failure patients/carers and the nature and effectiveness of spiritual interventions in heart failure care.\u0000\u0000\u0000SUMMARY\u0000Taken as a whole, studies exploring heart failure patients'/carers' needs reflected the broad spectrum of spirituality as defined by international consensus, however, some studies focused on only some aspects of spirituality and on advanced disease. All studies were limited. No single spiritual intervention was identified as effective in enhancing quality of life in patients with heart failure. Life review and relaxation/meditation appeared ineffective. Interventions, which included elements of 'talking' about spiritual matters, 'spiritual coping' and those involving a holistic person-centred team approach to care of which spiritual care was an aspect, are worth investigating further in well designed randomized controlled trials.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2019-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85895568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Autologous haematopoietic stem cell therapy for multiple sclerosis: a review for supportive care clinicians on behalf of the Autoimmune Diseases Working Party of the European Society for Blood and Marrow Transplantation 自体造血干细胞治疗多发性硬化症:代表欧洲血液和骨髓移植学会自身免疫性疾病工作组对支持性护理临床医生的回顾

IF 2.1 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2019-10-31 DOI: 10.1097/SPC.0000000000000466

A. Ismail, B. Sharrack, R. Saccardi, J. Moore, J. Snowden

{"title":"Autologous haematopoietic stem cell therapy for multiple sclerosis: a review for supportive care clinicians on behalf of the Autoimmune Diseases Working Party of the European Society for Blood and Marrow Transplantation","authors":"A. Ismail, B. Sharrack, R. Saccardi, J. Moore, J. Snowden","doi":"10.1097/SPC.0000000000000466","DOIUrl":"https://doi.org/10.1097/SPC.0000000000000466","url":null,"abstract":"Purpose of review In this review, we summarize the recently published literature that demonstrates the efficacy and safety of autologous haematopoietic stem cell therapy (AHSCT) in multiple sclerosis (MS) and highlight the importance of supportive care required for the safe and well-tolerated delivery of AHSCT. Recent findings MS is an autoimmune inflammatory and degenerative disorder of the central nervous system (CNS). In the majority of patients, the illness runs a relapsing remitting course (RRMS), culminating in a secondary progressive phase with gradual accumulation of fixed disabilities. Currently available disease-modifying therapies suppress CNS inflammation but have a limited effect on preventing disease progression for which there remains no effective therapy. Over the last two decades, there has been increasing evidence that AHSCT is a highly effective therapeutic strategy for treatment-resistant inflammatory types of MS, especially RRMS. Concerns about the safety of AHSCT in MS, usually a nonlife-threatening disease, have previously limited its use. However, AHSCT can now be delivered safely with major long-term benefits because of increasing transplant centre experience, judicious patient selection and good supportive care. Summary MS is currently the fastest growing indication for AHSCT in Europe. Supportive care before, during and after the transplant period is key to the successful delivery of AHSCT.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2019-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/SPC.0000000000000466","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61705763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Evaluating the effects of the pharmacological and nonpharmacological interventions to manage delirium symptoms in palliative care patients: systematic review. 评估缓和治疗患者谵妄症状的药理学和非药理学干预的效果:系统综述。

IF 2.1 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2019-09-03 DOI: 10.1097/SPC.0000000000000458

Luke Skelton, P. Guo

{"title":"Evaluating the effects of the pharmacological and nonpharmacological interventions to manage delirium symptoms in palliative care patients: systematic review.","authors":"Luke Skelton, P. Guo","doi":"10.1097/SPC.0000000000000458","DOIUrl":"https://doi.org/10.1097/SPC.0000000000000458","url":null,"abstract":"PURPOSE OF REVIEW\u0000There is a high prevalence of delirium in palliative care patients. This review aims to evaluate the effects of the pharmacological and nonpharmacological interventions used to manage delirium symptoms in this patient group.\u0000\u0000\u0000RECENT FINDINGS\u0000A recent study has suggested there is no role for antipsychotic medication in the management of delirium in palliative care patients, which is a move away from previous expert opinion. In addition, recent findings suggest there may be a role for the use of antipsychotics in combination with benzodiazepines in the management of agitated delirium.\u0000\u0000\u0000SUMMARY\u0000It is too early to abandon the use of antipsychotic medication entirely in the management of delirium, however there remains inadequate evidence to support the routine use of either pharmacological or nonpharmacological interventions for delirium treatment. Clinicians should determine the delirium subtype and severity, using this to inform the most appropriate pharmacological treatment if required. Further rigorously designed research is needed to seek clarity over whether the alleviation of symptoms is dose dependent, and to determine whether there is a severity threshold over which pharmacological interventions are most effective. Future research is required to evaluate nonpharmacological interventions in this population.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2019-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79305551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6