Hong Kong Medical Journal最新文献_第7页

Professor Gerald Choa and the Hong Kong Museum of Medical Sciences. 蔡国健教授及香港医学博物馆。

IF 2.6 4区医学

Hong Kong Medical Journal Pub Date : 2026-04-01 DOI: 10.12809/hkmj-hkmms202604

T W Wong

引用次数: 0

New guidance notes to drive rational prescription of antimicrobials for community settings in Hong Kong. 新指引指引推动香港社区合理使用抗微生物药物。

IF 2.6 4区医学

Hong Kong Medical Journal Pub Date : 2026-04-01 Epub Date: 2026-04-14 DOI: 10.12809/hkmj265190

E S K Ma, L S Ko, S K Mak, M C S Wong, A M W Chan

引用次数: 0

Subacute or chronic neurological toxicity following acute diquat poisoning: a case report. 急性双奎特中毒后的亚急性或慢性神经毒性：1例报告。

IF 2.6 4区医学

Hong Kong Medical Journal Pub Date : 2026-04-01 Epub Date: 2026-04-15 DOI: 10.12809/hkmj2513436

X Jin, Y Lu

引用次数: 0

Has the bacteriology of periprosthetic joint infection after total knee arthroplasty changed over time? A retrospective cohort study of 2171 patients. 全膝关节置换术后假体周围关节感染的细菌学是否随时间而改变？2171例患者的回顾性队列研究。

IF 3 4区医学

Hong Kong Medical Journal Pub Date : 2026-04-01 Epub Date: 2026-04-17 DOI: 10.12809/hkmj2310702

J R Khoo, P K Chan, J H Y Leung, V W K Chan, A Cheung, M H Luk, M H Cheung, H Fu, K Y Chiu

{"title":"Has the bacteriology of periprosthetic joint infection after total knee arthroplasty changed over time? A retrospective cohort study of 2171 patients.","authors":"J R Khoo, P K Chan, J H Y Leung, V W K Chan, A Cheung, M H Luk, M H Cheung, H Fu, K Y Chiu","doi":"10.12809/hkmj2310702","DOIUrl":"10.12809/hkmj2310702","url":null,"abstract":"Introduction: Periprosthetic joint infection (PJI) is an uncommon but serious complication of total knee arthroplasty (TKA). A previous retrospective cohort study at our institution reported a PJI incidence of 1.34% between 1993 and 2013. The present study aimed to determine whether the incidence of PJI after TKA has changed at our hospital and to evaluate changes in microbiological patterns between 2014 and 2021.Methods: In total, 2171 primary TKAs were performed at Queen Mary Hospital in Hong Kong between 1 January 2014 and 31 December 2021. All cases of PJI were identified using the Musculoskeletal Infection Society criteria. Patient demographics, PJI occurrence, and microbiological data were collected and compared with the previously published findings from the 1993-2013 PJI cohort.Results: The incidence of PJI after TKA was 0.64% between 2014 and 2021, representing a significant decrease from the incidence of 1.34% observed at our institution between 1993 and 2013 (P=0.018). There was no significant difference in the incidence of early-onset infection (P=0.095). Methicillin-sensitive Staphylococcus aureus was the most common causative organism, accounting for 57.1% (n=8) of our cohort and 26.5% (n=9) in the previous cohort.Conclusion: The incidence of PJI decreased significantly from 1.34% to 0.64% between the two study periods, suggesting the effectiveness of infection-reduction measures implemented at our institution. Minimal differences were observed in the microbiological patterns of PJI between the cohorts.","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":" ","pages":"114-120"},"PeriodicalIF":3.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validation of EuroSCORE II in post-cardiac surgery patients in a tertiary institution in Hong Kong. 在香港一所高等教育机构对心脏手术后患者进行EuroSCORE II的验证。

IF 3 4区医学

Hong Kong Medical Journal Pub Date : 2026-04-01 Epub Date: 2026-04-13 DOI: 10.12809/hkmj2514125

K H L Ng, K Wang, T Fujikawa, M W T Kwok, J Y K Ho, S C Y Chow, J W Y Chan, K Lim, A T C Chang, I C H Siu, R H L Wong

{"title":"Validation of EuroSCORE II in post-cardiac surgery patients in a tertiary institution in Hong Kong.","authors":"K H L Ng, K Wang, T Fujikawa, M W T Kwok, J Y K Ho, S C Y Chow, J W Y Chan, K Lim, A T C Chang, I C H Siu, R H L Wong","doi":"10.12809/hkmj2514125","DOIUrl":"10.12809/hkmj2514125","url":null,"abstract":"Introduction: This study aimed to assess the discriminatory ability and calibration performance of the European System for Cardiac Operative Risk Evaluation (EuroSCORE) II, a widely used risk prediction tool, in predicting postoperative mortality among patients undergoing cardiac surgery at Prince of Wales Hospital (PWH) in Hong Kong.Methods: Complete data from 4180 patients who underwent cardiac surgery at PWH between 2013 and 2023 were available for validation of EuroSCORE II and comparison of its discriminatory ability with the logistic EuroSCORE. Discriminatory performance was primarily assessed using the area under the receiver operating characteristic curve (AUROC). Calibration was evaluated using the Hosmer-Lemeshow test, coefficient of determination (R2), and normalised root mean square error (NRMSE).Results: EuroSCORE II demonstrated strong discrimination and good calibration for predicting 30-day mortality in the overall cohort (AUROC=0.829; Hosmer-Lemeshow P=0.155) and key subgroups: isolated coronary artery bypass grafting (CABG) [AUROC=0.847; P=0.113], isolated valve surgery (AUROC=0.810; P=0.162), and aortic surgery (AUROC=0.735; P=0.549). More than 85% of the variation in 30-day mortality (R2) was explained across these groups. Compared with the logistic EuroSCORE, EuroSCORE II showed improved discrimination and calibration, with higher AUROC values and lower NRMSE.Conclusion: EuroSCORE II demonstrates strong discriminatory ability and good calibration for predicting 30-day mortality among patients undergoing cardiac surgery and within key subgroups-isolated CABG, isolated valve surgery, and aortic surgery-in this cohort.","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":" ","pages":"126-134"},"PeriodicalIF":3.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147677767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of artificial intelligence in the Hong Kong Medical Licensing Examination. 人工智能在香港执业医师资格考试中的应用。

IF 2.6 4区医学

Hong Kong Medical Journal Pub Date : 2026-04-01 Epub Date: 2026-04-09 DOI: 10.12809/hkmj2514630

K K Yau, V W C Ma, V Y Y Li, S C L Au

引用次数: 0

Pericardial effusion with right atrial angiosarcoma differentiated from aortic dissection: a case report. 主动脉夹层分化为右心房血管肉瘤伴心包积液1例。

IF 2.6 4区医学

Hong Kong Medical Journal Pub Date : 2026-04-01 Epub Date: 2026-03-26 DOI: 10.12809/hkmj2513378

H Yang, F Zhang, X Zhang, Z Chen, Z Xu, G Zhang

引用次数: 0

Consensus statement on the use of Alzheimer's disease biomarkers and anti-amyloid therapies in Hong Kong. 在香港使用阿尔茨海默病生物标志物和抗淀粉样蛋白疗法的共识声明。

IF 3 4区医学

Hong Kong Medical Journal Pub Date : 2026-04-01 Epub Date: 2026-04-13 DOI: 10.12809/hkmj2514198

C K Shum, Y F Shea, T W Au Yeung, C C Y Chan, W C Chan, W K Cheng, N Y F Cheung, D H Y Cho, T K Chow, G C Y Fong, B Y M Ip, J S H Kwok, B M H Lai, L C W Lam, A T C Lee, C M Lok, K Y Mok, D K K Ng, D Y W Siu, P Y Yeung, S K F Tam

{"title":"Consensus statement on the use of Alzheimer's disease biomarkers and anti-amyloid therapies in Hong Kong.","authors":"C K Shum, Y F Shea, T W Au Yeung, C C Y Chan, W C Chan, W K Cheng, N Y F Cheung, D H Y Cho, T K Chow, G C Y Fong, B Y M Ip, J S H Kwok, B M H Lai, L C W Lam, A T C Lee, C M Lok, K Y Mok, D K K Ng, D Y W Siu, P Y Yeung, S K F Tam","doi":"10.12809/hkmj2514198","DOIUrl":"10.12809/hkmj2514198","url":null,"abstract":"Alzheimer's disease (AD) is the most common aetiology of cognitive impairment worldwide and in Hong Kong. There have been rapid advances in the use of biomarkers for the diagnosis of AD and in the availability of anti-amyloid therapies (AAT) to slow cognitive and functional decline. At present, there is no consensus in Hong Kong regarding the application of AD biomarkers or the use of AAT. A multidisciplinary group of 20 medical specialists from five professional societies discussed issues related to the application of biomarkers for the diagnosis of AD pathology and the use of AAT, and reviewed the evidence in the context of local experience to inform recommendations. A modified Delphi approach was adopted to finalise the recommendations. Consensus was defined as ≥75% agreement on a 9-point Likert scale among panellists. The panel finalised 26 consensus statements addressing the use of AD biomarkers, including neuroimaging and fluid biomarkers, as well as the use of AAT, including inclusion criteria, serial neuroimaging monitoring during treatment, and management of infusion reactions. These recommendations are relevant to the Hong Kong healthcare setting and may serve as guidance for doctors across specialties to facilitate appropriate management of AD.","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":" ","pages":"144-154"},"PeriodicalIF":3.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147677857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Medical history of Hong Kong Introduction-Anatomy of a city: why Hong Kong's history of medicine matters now. 香港医学史导论——剖析一个城市：为什么香港医学史对现在很重要。

IF 2.6 4区医学

Hong Kong Medical Journal Pub Date : 2026-02-01 DOI: 10.12809/hkmj-SA202602

R Sinha

引用次数: 0

The Hong Kong Hospital Authority reform: a historical perspective. Part 2: From reform blueprint to practice. 香港医院管理局改革：历史透视。第二部分：从改革蓝图到改革实践。

IF 2.6 4区医学

Hong Kong Medical Journal Pub Date : 2026-02-01 DOI: 10.12809/hkmj-hc202602

W S W Ho

引用次数: 0