Hong Kong Medical Journal最新文献

{"title":"Progressively enlarged Caesarean section scar endometriosis during pregnancy: case report and literature review.","authors":"Y Wu, X Li, J Shi, Y Li, J Leng, Y Dai","doi":"10.12809/hkmj2513208","DOIUrl":"https://doi.org/10.12809/hkmj2513208","url":null,"abstract":"","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147786372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Creamy clues to monogenic hypertriglyceridaemia.","authors":"A Fu, C Chan","doi":"10.12809/hkmj2513857","DOIUrl":"10.12809/hkmj2513857","url":null,"abstract":"","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":" ","pages":"174.e1-175.e2"},"PeriodicalIF":2.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147640365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The first Hong Kong-made three-dimensional-printed sternal implant for metastatic follicular thyroid carcinoma: a case report.","authors":"Y Luk, M M H Fung, K Y Sit, C X Fang, B H H Lang","doi":"10.12809/hkmj2513613","DOIUrl":"10.12809/hkmj2513613","url":null,"abstract":"","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":" ","pages":"164-167"},"PeriodicalIF":2.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147647185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obesity-driven thyroid cancer burden in middle-aged and older populations: temporal trends and projected trajectories based on the Global Burden of Disease study.","authors":"B Jiang, J Li, X Sun, J Qu, J Li, L Li, D Cai, Y Zhao, J Tian, J Lian, X Liu, C Zhang, S Niu, Y Yu, J Han","doi":"10.12809/hkmj2513477","DOIUrl":"10.12809/hkmj2513477","url":null,"abstract":"<p><strong>Introduction: </strong>High body mass index (BMI) in middle-aged and older individuals (≥40 years) is a leading risk factor for thyroid cancer-related morbidity and mortality; however, the quantifiable impact of elevated BMI on disability-adjusted life years (DALYs) and mortality in ageing populations remains underexplored. This study comprehensively evaluated the global burden of thyroid cancer attributable to elevated BMI by integrating past epidemiological trends, demographic variability and risk attribution models, and provided relevant projected trajectories using data from the Global Burden of Disease (GBD) study.</p><p><strong>Methods: </strong>We analysed mortality, DALYs, years of life lost (YLLs) and years lived with disability (YLDs). Temporal trends in disease burden from 1990 to 2021 were examined using linear regression models. Cluster analysis was used to assess region-specific burdens across GBD study regions. Finally, projections of future disease burden from 2022 to 2050 were generated using autoregressive integrated moving average and exponential smoothing models.</p><p><strong>Results: </strong>In 2021, high BMI contributed to 5255 thyroid cancer-related deaths (age-standardised mortality rate: 0.06 per 100 000) and 144 955 DALYs (age-standardised rate: 1.68 per 100 000); women and low-middle Socio-demographic Index regions were identified as high-risk subgroups. Projections indicate continued increases in mortality and overall disease burden through 2050.</p><p><strong>Conclusion: </strong>Substantial geographical heterogeneity in thyroid cancer burden was observed across GBD regions. Interventions targeting high-risk demographic groups and regions should be prioritised to reduce this growing disease burden.</p>","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":" ","pages":"135-143"},"PeriodicalIF":2.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147693122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New frontiers in rectal cancer treatment: implementing Watch and Wait in Hong Kong.","authors":"T M Y Yeung, K Futaba, S S M Ng","doi":"10.12809/hkmj2513415","DOIUrl":"10.12809/hkmj2513415","url":null,"abstract":"","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":" ","pages":"155-158"},"PeriodicalIF":2.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147692829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Descriptive analysis of platelet-rich plasma injection therapy in chronic musculoskeletal pain.","authors":"M H M Chu, W S Chan, A C Y Li, H M K Wong, H L Wong, K M Ho","doi":"10.12809/hkmj2514061","DOIUrl":"10.12809/hkmj2514061","url":null,"abstract":"<p><strong>Introduction: </strong>Platelet-rich plasma (PRP) injections have been used to manage various chronic pain conditions. However, evidence remains limited due to poor standardisation across practices. In this descriptive study, we aimed to characterise current PRP practice patterns at a university-affiliated private pain clinic in Hong Kong, focusing on case mix and treatment outcomes in patients with chronic musculoskeletal pain.</p><p><strong>Methods: </strong>This retrospective descriptive study included patients with diverse chronic musculoskeletal pain conditions aged 18 years or older who attended the CUHK Medical Centre Peter Hung Pain Specialist Clinic and received PRP injection therapy between January 2023 and December 2024. Improvements in pain and changes in oral analgesic use were recorded.</p><p><strong>Results: </strong>In total, 248 patients were included. Prior to PRP treatment, over 70% required multiple oral analgesics for pain control, including 55.6% taking antidepressants, 41.5% gabapentin or pregabalin, and 25.8% oral opioids. At first follow-up (median: 4 weeks, range: 1-20), more than 60% reported 'moderate' or 'much' improvement in pain symptoms. By 12 months post-treatment, fewer than 10% of patients in each category continued to require oral opioids, antidepressants, gabapentin, or pregabalin. Of the 26 patients (10.5%) who required a second PRP session, only one reported no improvement.</p><p><strong>Conclusion: </strong>These results highlight the potential utility of PRP in managing chronic musculoskeletal pain and underscore the need for randomised controlled trials to confirm its long-term impact on quality of life of patients.</p>","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":" ","pages":"121-125"},"PeriodicalIF":2.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147692851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of mild and major neurocognitive disorders in community and residential care homes in Hong Kong: considerations for multidimensional risk factor evaluation and intervention in primary care.","authors":"L C W Lam, W C Chan, A T C Lee, Z Huo, V C Lin, A W T Fung, S L Ma, C P W Cheng, S T Cheng, F H Y Lai, B H K Yip, S Y S Wong","doi":"10.12809/hkmj2412656","DOIUrl":"10.12809/hkmj2412656","url":null,"abstract":"<p><strong>Introduction: </strong>Given the rapid population ageing, the cognitive healthcare needs of older adults warrant attention. This study reports on the findings of the Hong Kong Mental Morbidity Survey for Older People (HKMMSOP), which evaluated the prevalence of neurocognitive disorders (NCD) and associated health factors that may inform primary care risk assessment and intervention.</p><p><strong>Methods: </strong>The HKMMSOP recruited 4871 participants aged 60 years or above through random sampling in Hong Kong during 2019 and 2023, including 4368 community-dwelling and 503 residential care home residents. Participants were assessed for cognitive function and mental status and completed health and lifestyle questionnaires. The prevalence of NCD and associated factors were evaluated with reference to the 2022 Hong Kong population.</p><p><strong>Results: </strong>The age- and gender-adjusted prevalences of mild and major NCD were 21.8% and 9.7%, respectively, among adults aged 60 years or above in Hong Kong. Approximately 70% of residents in long-term care (LTC) institutions had major NCD. Chronic diseases, sarcopenia risk, sensory impairments, and specific lifestyle habits were associated with cognitive function in logistic regression analyses adjusted for demographic confounders (P<0.05). Specialised medical services, including psychiatric care, were used by approximately 40% of community participants with major NCD.</p><p><strong>Conclusion: </strong>A range of NCD is prevalent in both community and LTC settings, with the highest rates observed among the oldest-old. To improve functional independence, community primary healthcare should prioritise early cardiovascular disease management, physical health maintenance, correction of sensory impairments, and promotion of intellectual and social engagement. For effective healthcare planning for frail older adults living in LTC institutions, the complex needs of nursing home residents with NCD should be addressed.</p>","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":" ","pages":"98-113"},"PeriodicalIF":2.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medical history of Hong Kong. Part I: Controlling fertility: the intrauterine device and biopolitics in Hong Kong, 1963-1974.","authors":"C C L Tsang","doi":"10.12809/hkmj-SA202604","DOIUrl":"https://doi.org/10.12809/hkmj-SA202604","url":null,"abstract":"","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":"32 2","pages":"179-182"},"PeriodicalIF":2.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147786422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reflecting on the past and looking to the future: an interview with Mr Thomas Chung-ching Chan, JP.","authors":"C Yang, N Su","doi":"10.12809/hkmj-hc202604","DOIUrl":"https://doi.org/10.12809/hkmj-hc202604","url":null,"abstract":"","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":"32 2","pages":"183-185"},"PeriodicalIF":2.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147786404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiple acyl-coenzyme A dehydrogenase deficiency presenting with myopathy and hypoglycaemia: a case report.","authors":"S S L Yeow, T S Wong, G W K Poon, G Yuan","doi":"10.12809/hkmj2512906","DOIUrl":"10.12809/hkmj2512906","url":null,"abstract":"","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":" ","pages":"159-160"},"PeriodicalIF":2.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147677774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}