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Effect of Wuzi Yanzong on semen quality in subfertile men: a double-blind, randomised, placebo-controlled trial (abridged secondary publication). 五子炎宗对不育男性精液质量的影响：一项双盲、随机、安慰剂对照试验。
IF 3.1 4区 医学
Hong Kong Medical Journal Pub Date : 2025-06-01
T C Li, R C C Wang, Z X Lin, G W S Kong, J P W Chung, H W Lok, D Y L Chan
{"title":"Effect of Wuzi Yanzong on semen quality in subfertile men: a double-blind, randomised, placebo-controlled trial (abridged secondary publication).","authors":"T C Li, R C C Wang, Z X Lin, G W S Kong, J P W Chung, H W Lok, D Y L Chan","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":"31 Suppl 3 3","pages":"40"},"PeriodicalIF":3.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144555474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Machine learning models for hip fracture prediction using electronic medical records: abridged secondary publication. 使用电子医疗记录预测髋部骨折的机器学习模型：次要出版物节略。
IF 3.1 4区 医学
Hong Kong Medical Journal Pub Date : 2025-06-01
G H Y Li, C L Cheung, K C B Tan, T C Y Kwok, W C Y Lau
{"title":"Machine learning models for hip fracture prediction using electronic medical records: abridged secondary publication.","authors":"G H Y Li, C L Cheung, K C B Tan, T C Y Kwok, W C Y Lau","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":"31 Suppl 3 3","pages":"4-11"},"PeriodicalIF":3.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144555479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Survival estimate models of cancer patients with spinal metastases: big data analytics to aid daily clinical practice (abridged secondary publication). 脊柱转移癌患者的生存评估模型：大数据分析以辅助日常临床实践（次要出版物节略）。
IF 3.1 4区 医学
Hong Kong Medical Journal Pub Date : 2025-06-01
K Y H Kwan, C L Cheung, K M C Cheung, R Luo, D M C Poon, T W Lam, T C Lam
{"title":"Survival estimate models of cancer patients with spinal metastases: big data analytics to aid daily clinical practice (abridged secondary publication).","authors":"K Y H Kwan, C L Cheung, K M C Cheung, R Luo, D M C Poon, T W Lam, T C Lam","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":"31 Suppl 3 3","pages":"12-13"},"PeriodicalIF":3.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144555484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adrenal insufficiency due to etomidate inhalation via electronic cigarettes: three local cases. 电子烟吸入依托咪酯致肾上腺功能不全3例。
IF 3.1 4区 医学
Hong Kong Medical Journal Pub Date : 2025-06-01 Epub Date: 2025-06-04 DOI: 10.12809/hkmj2412244
Y K Chung, Y T Cheung, C S Y Chan, C C Wong, A C C Fu, Y Y Lam, C Y Lee
{"title":"Adrenal insufficiency due to etomidate inhalation via electronic cigarettes: three local cases.","authors":"Y K Chung, Y T Cheung, C S Y Chan, C C Wong, A C C Fu, Y Y Lam, C Y Lee","doi":"10.12809/hkmj2412244","DOIUrl":"10.12809/hkmj2412244","url":null,"abstract":"","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":" ","pages":"229-232"},"PeriodicalIF":3.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144217313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of nerve sparing on erectile dysfunction and urinary incontinence in robot-assisted radical prostatectomy. 神经保留对机器人辅助根治性前列腺切除术中勃起功能障碍和尿失禁的影响。
IF 3.1 4区 医学
Hong Kong Medical Journal Pub Date : 2025-06-01 Epub Date: 2025-06-10 DOI: 10.12809/hkmj2411709
O W K Tsui, K C H Shing, A P M Lam, S L Ng, S Chun, C F Tsang, T C T Lai, R Na, H L Wong, B S H Ho, A T L Ng
{"title":"Effects of nerve sparing on erectile dysfunction and urinary incontinence in robot-assisted radical prostatectomy.","authors":"O W K Tsui, K C H Shing, A P M Lam, S L Ng, S Chun, C F Tsang, T C T Lai, R Na, H L Wong, B S H Ho, A T L Ng","doi":"10.12809/hkmj2411709","DOIUrl":"10.12809/hkmj2411709","url":null,"abstract":"<p><strong>Introduction: </strong>In 2020, there were >1.4 million new prostate cancer cases and >370 000 related deaths reported globally. Robot-assisted radical prostatectomy (RARP) is a surgical method used to eradicate localised prostate cancer. However, erectile dysfunction (ED) and urinary incontinence (UI) are common side-effects. This retrospective cohort study investigated erectile function, urinary continence, and oncological outcomes of nerve sparing (NS) in RARP.</p><p><strong>Methods: </strong>In total, 431 patients who underwent RARP in our institution between January 2018 and April 2023 were recruited; all had attended postoperative follow-up. Regarding ED outcome, patients with a preoperative International Index of Erectile Function-5 (IIEF-5) score of 7 or below 7 were excluded from analysis. Patient demographics, 1-hour pad test results, IIEF-5 questionnaire results, and pathological parameters were analysed.</p><p><strong>Results: </strong>Patients with bilateral NS had a higher mean postoperative IIEF-5 score after 2 months (7.60 vs 3.19 in non-NS patients, P=0.037; 7.60 vs 2.50 in unilateral NS patients, P=0.020) and 3 months (7.40 vs 2.06 in unilateral NS patients; P=0.027). They also had lower mean urine leakage volume in the 1-hour pad test after 1 month (16.40 g vs 49.44 g in non-NS patients, P<0.001; 16.40 g vs 50.82 g in unilateral NS patients, P=0.010) and 2 months (13.60 g vs 35.45 g in non-NS patients; P=0.009). No significant differences were observed in ED or UI between non-NS and unilateral or bilateral NS at 6 and 12 months. There was no correlation between positive surgical margin and NS.</p><p><strong>Conclusion: </strong>Bilateral NS had significant short-term effects on early recovery of erectile function and urinary continence, relative to unilateral NS and non-NS groups, without compromising oncological outcomes.</p>","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":" ","pages":"218-224"},"PeriodicalIF":3.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advancing next-generation sequencing access: aspirations for next-generation sequencing policy and patient access in Hong Kong. 推进新一代测序获取：对香港新一代测序政策和患者获取的期望。
IF 3.1 4区 医学
Hong Kong Medical Journal Pub Date : 2025-06-01 Epub Date: 2025-06-13 DOI: 10.12809/hkmj255177
J Au, R Mok, C Fung, M Tham, Y S Teh, A Sen, W Brown, M C S Wong
{"title":"Advancing next-generation sequencing access: aspirations for next-generation sequencing policy and patient access in Hong Kong.","authors":"J Au, R Mok, C Fung, M Tham, Y S Teh, A Sen, W Brown, M C S Wong","doi":"10.12809/hkmj255177","DOIUrl":"10.12809/hkmj255177","url":null,"abstract":"","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":" ","pages":"186-189"},"PeriodicalIF":3.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144286922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glass ionomer sealant versus fluoride varnish in preventing occlusal caries among preschool children: a randomised controlled trial (abridged secondary publication). 玻璃离子密封剂与氟化物清漆在预防学龄前儿童牙合龋齿中的作用：一项随机对照试验（节略的二次出版物）。
IF 3.1 4区 医学
Hong Kong Medical Journal Pub Date : 2025-06-01
C K Y Yiu, E C M Lo, G H M Lee
{"title":"Glass ionomer sealant versus fluoride varnish in preventing occlusal caries among preschool children: a randomised controlled trial (abridged secondary publication).","authors":"C K Y Yiu, E C M Lo, G H M Lee","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":"31 Suppl 3 3","pages":"27-29"},"PeriodicalIF":3.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144555476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Promoting advance care planning in people with early dementia and their family caregivers. 促进早期痴呆患者及其家庭照护者的预先照护规划。
IF 3.1 4区 医学
Hong Kong Medical Journal Pub Date : 2025-06-01
C Y Yeung, H Y L Chan
{"title":"Promoting advance care planning in people with early dementia and their family caregivers.","authors":"C Y Yeung, H Y L Chan","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":"31 Suppl 3 3","pages":"23-26"},"PeriodicalIF":3.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144555482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fragile X syndrome: genetic and clinical profile in the Hong Kong Chinese population. 脆性X染色体综合征：香港华人的遗传和临床特征。
IF 3.1 4区 医学
Hong Kong Medical Journal Pub Date : 2025-06-01 Epub Date: 2025-06-05 DOI: 10.12809/hkmj2411942
C W M Au, H M Luk, S Ho, S W Cheng, S T S Lam, B H Y Chung, S C Chong, I F M Lo
{"title":"Fragile X syndrome: genetic and clinical profile in the Hong Kong Chinese population.","authors":"C W M Au, H M Luk, S Ho, S W Cheng, S T S Lam, B H Y Chung, S C Chong, I F M Lo","doi":"10.12809/hkmj2411942","DOIUrl":"10.12809/hkmj2411942","url":null,"abstract":"<p><strong>Introduction: </strong>Fragile X syndrome (FXS) is a common inherited cause of intellectual disability, and FXS testing is recommended as a first-line genetic investigation for global developmental delay or intellectual disability. This retrospective study evaluated the diagnostic yield of FXS testing and clinical features in Chinese patients in Hong Kong.</p><p><strong>Methods: </strong>From 1993 to 2022, 7291 patients referred to the Clinical Genetic Service for neurodevelopmental conditions (eg, developmental delay, autism spectrum disorder, and intellectual disability) underwent FXS testing. In total, 103 individuals from 61 families were confirmed to have an <i>FMR1</i> full mutation, including 59 index cases and 44 family members. Clinical features of 70 Chinese patients with FXS, including growth, neurobehavioural features, and other co-morbidities, were evaluated.</p><p><strong>Results: </strong>The diagnostic yield of FXS testing was 0.8%. The median age at diagnosis for index cases was 4.1 years, with a trend towards earlier diagnosis in recent years. In 27 families (44.2%), multiple members carried a full mutation. Prenatal diagnosis was arranged in 11% of families. Developmental delay was observed in all males, compared with 45.0% of females. Intellectual disability affected 86.0% of males but only 30.0% of females. Common co-morbidities included obesity, autism spectrum disorder, attention-deficit/hyperactivity disorder, epilepsy, gastrointestinal problems, and sleep disturbances. Features such as strabismus, scoliosis, and mitral valve prolapse were rarely reported.</p><p><strong>Conclusion: </strong>Fragile X syndrome is more than a pure neurodevelopmental disorder. Our findings highlight the importance of early diagnosis and subsequent management, with awareness of relevant surveillance and management guidelines.</p>","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":" ","pages":"199-207"},"PeriodicalIF":3.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144227303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rethink personalised sudden cardiac death risk assessment in non-dilated left ventricular cardiomyopathy: a case report. 重新考虑非扩张型左室心肌病个体化心源性猝死风险评估：1例报告。
IF 3.1 4区 医学
Hong Kong Medical Journal Pub Date : 2025-06-01 Epub Date: 2025-04-14 DOI: 10.12809/hkmj2412128
K W C Lun, J C Y Lee, E C Y Wong, M K Y Lee, D P H Lee
{"title":"Rethink personalised sudden cardiac death risk assessment in non-dilated left ventricular cardiomyopathy: a case report.","authors":"K W C Lun, J C Y Lee, E C Y Wong, M K Y Lee, D P H Lee","doi":"10.12809/hkmj2412128","DOIUrl":"10.12809/hkmj2412128","url":null,"abstract":"","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":" ","pages":"236-239"},"PeriodicalIF":3.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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