Hong Kong Medical Journal最新文献

{"title":"Normalising high-stakes innovation: insights from Hong Kong's first intraoperative magnetic resonance imaging service.","authors":"C K M Lam, P Y S Lee, W N Ho, S T Wong, B C P Cheng, I Y C Wong","doi":"10.12809/hkmj2514258","DOIUrl":"10.12809/hkmj2514258","url":null,"abstract":"","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":" ","pages":"297-299"},"PeriodicalIF":3.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148537366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence and predictors of radiation proctitis or radiation cystitis after radiotherapy in patients with prostate cancer.","authors":"I C H Ko, C H T Mok, D K W Leung, C H M Wong, J H C Chow, A Mok, A Q Liu, B W H Siu, S K K Yuen, C H Yee, P K F Chiu, J Y C Teoh, K Wong, C F Ng","doi":"10.12809/hkmj2412691","DOIUrl":"10.12809/hkmj2412691","url":null,"abstract":"<p><strong>Introduction: </strong>This study evaluated the cumulative incidences of radiation cystitis (RC) and radiation proctitis (RP) after radiotherapy (RT) for localised and metastatic prostate cancer (PCa). It also analysed potential risk factors associated with resultant emergency admissions.</p><p><strong>Methods: </strong>Between January 2001 and January 2023, 762 patients who underwent primary RT for localised PCa and low-volume metastatic hormone-sensitive PCa, as well as salvage or adjuvant RT after prostatectomy, were retrospectively analysed. The severities of RC and RP were assessed using the Common Terminology Criteria for Adverse Events version 5.0. Severe events were defined as grade 3 or higher.</p><p><strong>Results: </strong>The median follow-up time was 59 months. The 5-year/10-year cumulative incidences of RC and severe RC were 11%/20% and 6.3%/12%, respectively. Among 58 patients with severe RC, 11 (19.0%) required endoscopic haemostasis. The 5-year/10-year cumulative incidences of RP and severe RP were 20%/21% and 7.5%/8.4%, respectively. Among 57 patients with severe RP, 38 (67%) required endoscopic haemostasis. Multivariable Cox regression analysis identified adjuvant or salvage RT as a predictor of RC; primary RT was identified as a predictor of RP. A bladder volume receiving >60 Gy of >25% was identified as a predictor of RC and severe RC. A rectal volume receiving >70 Gy of >10% was identified as a predictor of RP and severe RP. Antiplatelet medication was a significant risk factor for RC, RP, and severe events.</p><p><strong>Conclusion: </strong>Radiation cystitis and RP are common complications of RT in patients with PCa. Comprehensive counselling regarding these potential long-term adverse effects is imperative.</p>","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":" ","pages":"225-233"},"PeriodicalIF":3.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148266466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mysterious deaths of monkeys in the Hong Kong Zoological and Botanical Gardens and anxious parents: paediatricians' perspectives and health education opportunities.","authors":"K L Hon, A K C Leung, G P G Fung, J S C Kung, L L Ooi, K K Y Leung","doi":"10.12809/hkmj2512899","DOIUrl":"10.12809/hkmj2512899","url":null,"abstract":"","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":" ","pages":"263-267"},"PeriodicalIF":3.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148266471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hantavirus infection: emerging global public health concerns.","authors":"M Y W Kwan, M C S Wong, I F N Hung","doi":"10.12809/hkmj265193","DOIUrl":"10.12809/hkmj265193","url":null,"abstract":"","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":" ","pages":"197-199"},"PeriodicalIF":3.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148254129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Hong Kong Hospital Authority reform: a historical perspective. Part 3: From organisation reform to improving clinical quality and population health.","authors":"W S W Ho","doi":"10.12809/hkmj-hc202606","DOIUrl":"https://doi.org/10.12809/hkmj-hc202606","url":null,"abstract":"","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":"32 3","pages":"271-278"},"PeriodicalIF":3.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148320132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pre-donation screening for blood safety: comparison between 3- and 6-month deferral of men who have sex with men and the incorporation of individual risk assessment.","authors":"S L Chung, N S Wong, J N S Leung, C K Lee, S S Lee","doi":"10.12809/hkmj2412681","DOIUrl":"10.12809/hkmj2412681","url":null,"abstract":"<p><strong>Introduction: </strong>Advances in blood donor screening have supported the shortening of deferral intervals and incorporation of individual risk assessment. This study investigated the potential impacts of comparing 3‑ and 6‑month deferral periods for men who have sex with men and introducing a behaviour‑based individual risk assessment policy in Hong Kong, particularly on donor eligibility and blood safety.</p><p><strong>Methods: </strong>A cross-sectional study was conducted in March 2024, recruiting individuals who had successfully donated blood in October 2023 in Hong Kong. Participants completed a survey on transfusion-transmissible infection risk-related deferrable behaviours, as described in the pre-donation screening questionnaire, and the United States Food and Drug Administration-proposed individual risk assessment items within 6 months before donation. Bivariable and multivariable (backward) logistic regression analyses were performed to identify factors associated with non-compliance. Presumptive non-compliance rates were calculated based on the timing of the most recent reported risk behaviour.</p><p><strong>Results: </strong>Of 2268 responses received, 1720 (median age=46 years; 50.8% male) were analysed. The non-compliance rate under the prevailing 6-month deferral policy was 4.01% (95% confidence interval [95% CI]=3.16%-5.02%). Non-compliant donors were more likely to be male (adjusted odds ratio [aOR]=2.049, 95% CI=1.216-3.451) and to perceive themselves as healthy (aOR=1.248, 95% CI=1.024-1.521), but less likely to believe in personal responsibility for blood safety (aOR=0.846, 95% CI=0.766-0.935). Presumptive non-compliance rates were 2.79% for 3-month deferral under the prevailing policy and 2.27% for 3-month deferral incorporating individual risk assessment. Of the five individuals who would have been deferred for male-to-male sexual activities under the prevailing policy with a 3-month deferral period, two would have become eligible under individual risk assessment.</p><p><strong>Conclusions: </strong>Shortening deferral intervals had modest effects on donor compliance. Incorporating individual risk assessment could improve identification of potential donors with higher-risk sexual behaviours while moderately expanding the donor pool.</p>","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":" ","pages":"208-216"},"PeriodicalIF":3.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148273410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uncovering the elusive nature of C3 glomerulopathy: a case report.","authors":"T H M Wu, F T W Ho, E Y L Au, E Y H Chan, A L T Ma","doi":"10.12809/hkmj2513327","DOIUrl":"10.12809/hkmj2513327","url":null,"abstract":"","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":" ","pages":"258-261"},"PeriodicalIF":3.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148151293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medical history of Hong Kong. Part II: Healers in the maze: unravelling the myths of Kowloon Walled City practitioners.","authors":"S C P Wu","doi":"10.12809/hkmj-SA202606","DOIUrl":"https://doi.org/10.12809/hkmj-SA202606","url":null,"abstract":"","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":"32 3","pages":"268-270"},"PeriodicalIF":3.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148320115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Progressively enlarged Caesarean section scar endometriosis during pregnancy: case report and literature review.","authors":"Y Wu, X Li, J Shi, Y Li, J Leng, Y Dai","doi":"10.12809/hkmj2513208","DOIUrl":"10.12809/hkmj2513208","url":null,"abstract":"","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":" ","pages":"246-248"},"PeriodicalIF":3.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147786372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative implications of Hong Kong's Advance Decision on Life-sustaining Treatment Ordinance.","authors":"V N M Lau, A K M Chan","doi":"10.12809/hkmj265191","DOIUrl":"10.12809/hkmj265191","url":null,"abstract":"","PeriodicalId":48828,"journal":{"name":"Hong Kong Medical Journal","volume":" ","pages":"192-195"},"PeriodicalIF":3.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148260149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}