Diego Grinman , Pamela Dann , Marya Shanabrough , Tamas Horvath , John Wysolmerski
{"title":"Cancer-associated hypercalcemia signals through the hindbrain to cause anorexia","authors":"Diego Grinman , Pamela Dann , Marya Shanabrough , Tamas Horvath , John Wysolmerski","doi":"10.1016/j.jbo.2024.100535","DOIUrl":"https://doi.org/10.1016/j.jbo.2024.100535","url":null,"abstract":"","PeriodicalId":48806,"journal":{"name":"Journal of Bone Oncology","volume":"45 ","pages":"Article 100535"},"PeriodicalIF":3.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212137424000150/pdfft?md5=d4f19e1bec9ff1c1eed0506e0f613455&pid=1-s2.0-S2212137424000150-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140641230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lijun Yao , Julia T. Wang , Reyka G. Jayasinghe , Julie O'Neal , Chia-Feng Tsai , Michael P. Rettig , Yizhe Song , Ruiyang Liu , Yanyan Zhao , Omar M. Ibrahim , Mark A. Fiala , Julie M. Fortier , Siqi Chen , Leah Gehrs , Fernanda Martins Rodrigues , Michael C. Wendl , Daniel Kohnen , Andrew Shinkle , Song Cao , Steven M. Foltz , John F. DiPersio
{"title":"#15. Single-cell discovery and multi-omic characterization of therapeutic targets in multiple myeloma","authors":"Lijun Yao , Julia T. Wang , Reyka G. Jayasinghe , Julie O'Neal , Chia-Feng Tsai , Michael P. Rettig , Yizhe Song , Ruiyang Liu , Yanyan Zhao , Omar M. Ibrahim , Mark A. Fiala , Julie M. Fortier , Siqi Chen , Leah Gehrs , Fernanda Martins Rodrigues , Michael C. Wendl , Daniel Kohnen , Andrew Shinkle , Song Cao , Steven M. Foltz , John F. DiPersio","doi":"10.1016/j.jbo.2024.100553","DOIUrl":"https://doi.org/10.1016/j.jbo.2024.100553","url":null,"abstract":"","PeriodicalId":48806,"journal":{"name":"Journal of Bone Oncology","volume":"45 ","pages":"Article 100553"},"PeriodicalIF":3.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212137424000332/pdfft?md5=fe41ee42fbdff8ce028e6a10ee8d9718&pid=1-s2.0-S2212137424000332-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140641234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"#48. N-cadherin in tumor-associated Osx+ cells is anti-tumorigenic","authors":"Toshi Sugatani, Roberto Civitelli","doi":"10.1016/j.jbo.2024.100586","DOIUrl":"https://doi.org/10.1016/j.jbo.2024.100586","url":null,"abstract":"","PeriodicalId":48806,"journal":{"name":"Journal of Bone Oncology","volume":"45 ","pages":"Article 100586"},"PeriodicalIF":3.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212137424000666/pdfft?md5=536a4928c72288906eda81387e5cfb01&pid=1-s2.0-S2212137424000666-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140641268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shuzhong Liu , Xi Zhou , Yong Liu , Jianguo Zhang , Weibo Xia
{"title":"Preoperative evaluation and orthopedic surgical strategies for tumor-induced osteomalacia","authors":"Shuzhong Liu , Xi Zhou , Yong Liu , Jianguo Zhang , Weibo Xia","doi":"10.1016/j.jbo.2024.100600","DOIUrl":"https://doi.org/10.1016/j.jbo.2024.100600","url":null,"abstract":"<div><p>Tumor-induced osteomalacia (TIO), also known as oncogenic osteomalacia, is very rare, with about 1000 reported cases globally. Removing most TIO culprit tumors requires the evaluation and intervention of orthopedic doctors. However, orthopedic doctors often have a poor understanding of the optical treatment of TIO due to its rarity. In addition, most TIO patients lack specific clinical manifestations. Also, the clinical localization and qualitative diagnosis of TIO are difficult and thus can easily be misdiagnosed and mistreated. Furthermore, the true incidence rate of TIO may be underestimated. Although many breakthroughs have been made in exploring the pathogenesis, clinical diagnosis, and treatment of TIO, rational and standardized orthopedic surgical treatment experience summary and sorting for TIO patients are lacking. In this article, the recent experience and progress in the field of orthopedic surgical treatment for TIO globally have been summarized, providing a theoretical basis and new clinical practice guidance for the rational treatment of TIO patients.</p></div>","PeriodicalId":48806,"journal":{"name":"Journal of Bone Oncology","volume":"45 ","pages":"Article 100600"},"PeriodicalIF":3.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212137424000800/pdfft?md5=33b6d95aeef87894de1a0b6f75140758&pid=1-s2.0-S2212137424000800-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140330734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Richard Laforest , Anchal Ghai , Tyler J. Fraum , Reiko Oyama , Jennifer Frye , Helen Kaemmerer , Greg Gaehle , Tom Voller , Cedric Mpoy , Buck E. Rogers , Mark Fiala , Kooresh I. Shoghi , Samuel Achilefu , Michael Rettig , Ravi Vij , John F. DiPersio , Sally Schwarz , Monica Shokeen , Farrokh Dehdashti
{"title":"#27. First-in-human evaluation of safety and dosimetry of 64Cu-LLP2A for PET imaging","authors":"Richard Laforest , Anchal Ghai , Tyler J. Fraum , Reiko Oyama , Jennifer Frye , Helen Kaemmerer , Greg Gaehle , Tom Voller , Cedric Mpoy , Buck E. Rogers , Mark Fiala , Kooresh I. Shoghi , Samuel Achilefu , Michael Rettig , Ravi Vij , John F. DiPersio , Sally Schwarz , Monica Shokeen , Farrokh Dehdashti","doi":"10.1016/j.jbo.2024.100565","DOIUrl":"https://doi.org/10.1016/j.jbo.2024.100565","url":null,"abstract":"","PeriodicalId":48806,"journal":{"name":"Journal of Bone Oncology","volume":"45 ","pages":"Article 100565"},"PeriodicalIF":3.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212137424000459/pdfft?md5=a8d5340fa39732645f4bc066c2421f4e&pid=1-s2.0-S2212137424000459-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140641266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"#11. Bone marrow adipocyte-induced increases in lipid content and fatty acid binding proteins may support proliferation in myeloma cells","authors":"Heather Fairfield , Mariah Farrell , Kristen Krip , Patricia Kayoyo Masengo , Michaela Reagan","doi":"10.1016/j.jbo.2024.100549","DOIUrl":"https://doi.org/10.1016/j.jbo.2024.100549","url":null,"abstract":"","PeriodicalId":48806,"journal":{"name":"Journal of Bone Oncology","volume":"45 ","pages":"Article 100549"},"PeriodicalIF":3.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212137424000290/pdfft?md5=b2ce0f860fc59431e7568f3af79ca1fd&pid=1-s2.0-S2212137424000290-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140640765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shiyu Yuan , Nathan K. Hoggard , Noriko Kantake , Blake E. Hildreth III , Thomas J. Rosol
{"title":"#34. The effect of dickkopf-1 (DKK-1) on prostate cancer growth and bone metastasis using the canine osteoblastic Probasco cell line","authors":"Shiyu Yuan , Nathan K. Hoggard , Noriko Kantake , Blake E. Hildreth III , Thomas J. Rosol","doi":"10.1016/j.jbo.2024.100572","DOIUrl":"https://doi.org/10.1016/j.jbo.2024.100572","url":null,"abstract":"","PeriodicalId":48806,"journal":{"name":"Journal of Bone Oncology","volume":"45 ","pages":"Article 100572"},"PeriodicalIF":3.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212137424000526/pdfft?md5=da5a26feb6e458f2a41ed2df4b91be59&pid=1-s2.0-S2212137424000526-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140640909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katherine Clifton , Jingqin Rosy Luo , Roberto Civitelli , Stefanie Geisler , Qamar Khan , Ciara O'Sullivan , Ajay Aggarwal , Sheila Stewart , Cynthia Ma
{"title":"#31. A Phase I/II trial of ATI-2231 with Phase Ia in advanced soild tumor malignancies followed by Phase Ib/II in combination with capecitabine in patients with hormone receptor-positive (HR+) and HER2-negative metastatic breast cancer","authors":"Katherine Clifton , Jingqin Rosy Luo , Roberto Civitelli , Stefanie Geisler , Qamar Khan , Ciara O'Sullivan , Ajay Aggarwal , Sheila Stewart , Cynthia Ma","doi":"10.1016/j.jbo.2024.100569","DOIUrl":"https://doi.org/10.1016/j.jbo.2024.100569","url":null,"abstract":"","PeriodicalId":48806,"journal":{"name":"Journal of Bone Oncology","volume":"45 ","pages":"Article 100569"},"PeriodicalIF":3.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212137424000496/pdfft?md5=76dd55d3f600fbe76e47aa88d2548ea1&pid=1-s2.0-S2212137424000496-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140641023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"#7. Downstream effects of Gli2 targeting on tumor-immune cell crosstalk in bone metastatic breast cancer","authors":"Natalie Bennett , Julie Rhoades","doi":"10.1016/j.jbo.2024.100545","DOIUrl":"https://doi.org/10.1016/j.jbo.2024.100545","url":null,"abstract":"","PeriodicalId":48806,"journal":{"name":"Journal of Bone Oncology","volume":"45 ","pages":"Article 100545"},"PeriodicalIF":3.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212137424000253/pdfft?md5=ac7f34c3222cf90bd8acd5fd94eb9f8e&pid=1-s2.0-S2212137424000253-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140641201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}