Lancet Psychiatry最新文献

{"title":"US FDA premarket approval of tDCS depression treatment is not yet scientifically justified.","authors":"Jana Klaus,Fenne M Smits,André Aleman,Chris Baeken,Philip van Eijndhoven,Odile A van den Heuvel,Dennis J L G Schutter","doi":"10.1016/s2215-0366(26)00092-1","DOIUrl":"https://doi.org/10.1016/s2215-0366(26)00092-1","url":null,"abstract":"","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"14 1","pages":""},"PeriodicalIF":64.3,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147719383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to Lancet Psychiatry 2025; 12: 44–53","authors":"","doi":"10.1016/s2215-0366(26)00115-x","DOIUrl":"https://doi.org/10.1016/s2215-0366(26)00115-x","url":null,"abstract":"","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"24 1","pages":""},"PeriodicalIF":64.3,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147680945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Screening-to-intervention pathway for child anxiety problems alongside usual school practice versus usual school practice only (iCATSi2i): a cluster-randomised, controlled trial in primary schools in England","authors":"Tessa Reardon, Obioha C Ukoumunne, Lucy Taylor, Susan Ball, Mara Violato, Michael Larkin, Jennifer Fisk, Gemma Halliday, Shuye Yu, Victoria Williamson, Tamsin Ford, Alastair Gray, Claire Hill, Bec Jasper, Ian Macdonald, Fran Morgan, Jack Pollard, Michelle Sancho, Falko F Sniehotta, Susan H Spence, Cathy Creswell","doi":"10.1016/s2215-0366(26)00064-7","DOIUrl":"https://doi.org/10.1016/s2215-0366(26)00064-7","url":null,"abstract":"<h3>Background</h3>Screening for anxiety problems in primary schools and offering parent-led cognitive behavioural therapy (CBT) via online and telephone support for those who screen positive could address key barriers to effective early intervention for some of the most prevalent child mental disorders. We aimed to evaluate outcomes from a screening-to-intervention pathway for child anxiety problems alongside usual school provision compared with assessment and usual school provision only.<h3>Methods</h3>iCATSi2i was a pragmatic, parallel-group, superiority, cluster-randomised, controlled trial in 84 primary and junior schools in England with at least two year-4 classes. Children aged 8–9 years in participating classes who were not opted out by their parent were eligible to participate. After baseline assessments, schools (clusters) were randomly assigned (1:1) to screening, feedback, and intervention, alongside usual school practice (intervention group) or assessment and usual school practice only (control group), stratified by school-level deprivation. Before allocation, schools were ordered by the number of children who screened positive for anxiety problems at baseline (target population). Block randomisation was used with block sizes of two and four. Trial statisticians were masked to group allocation until datasets were ready for final analysis. In schools in the intervention group all parents in sampled classes were invited to complete a two-item screening questionnaire (iCATS-2) at baseline and received feedback on the screening outcome (after randomisation); parents of children who screened positive for anxiety problems (target population) were offered parent-led CBT delivered via online and telephone support, using the Online Support and Intervention for Child Anxiety (OSI) platform (and this was available for other families on request); a single whole-class session on identifying and managing fears and worries was also provided. In both groups, assessments (including the screening questionnaire) were completed and schools continued with usual provision. The primary outcome was screen-negative for anxiety problems (score 0–2 on the parent-reported iCATS-2) versus screen-positive (score 3–6) in the target population at 12 months. Primary analyses were conducted in the intention-to-treat population, with missing data imputed. Adverse events were monitored and recorded throughout. The trial was registered with the ISRCTN registry, ISRCTN76119074, and the study is complete. The study management group included individuals with relevant lived experience.<h3>Findings</h3>We recruited participants and collected baseline assessments between Jan 6, and Nov 30, 2022. Parents of 1459 children (27% of 5335 children in participating classes) completed the screening questionnaire, and 409 screened positive (target population). On the basis of parent report, 222 (54%) of 408 children who screened positive were female, 185 (45%) were male, and one (<","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"21 1","pages":""},"PeriodicalIF":64.3,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147655845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clozapine rechallenge after neutropenia: a retrospective cohort study in the UK","authors":"Ebenezer Oloyede DPhil, Olubanke Dzahini MSc, Prof James MacCabe PhD, Cecilia Casetta MD, Dominic Oliver PhD, Prof Sukhi Shergill PhD, Prof Dan Siskind PhD, Prof Philip McGuire PhD, Eromona Whiskey PhD, Prof David Taylor PhD","doi":"10.1016/s2215-0366(26)00061-1","DOIUrl":"https://doi.org/10.1016/s2215-0366(26)00061-1","url":null,"abstract":"Clozapine is contraindicated in patients with a history of neutropenia suspected to be clozapine-induced agranulocytosis. Under exceptional circumstances, patients may be rechallenged with clozapine under an off-licence agreement. The evidence regarding clozapine rechallenge after suspected clozapine-induced neutropenia remains sparse and conflicting. In this observational study, we aimed to review the outcomes of patients rechallenged with clozapine using data from the two largest clozapine manufacturers in the UK.","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"21 1","pages":""},"PeriodicalIF":64.3,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147642194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Poetry as externalisation after corporal punishment.","authors":"Awu Isaac Oben","doi":"10.1016/s2215-0366(26)00067-2","DOIUrl":"https://doi.org/10.1016/s2215-0366(26)00067-2","url":null,"abstract":"","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"85 1","pages":"289-290"},"PeriodicalIF":64.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147490048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental health needs and personality disorders in humanitarian settings.","authors":"Peter Ventevogel,Raghda Sleit,Esubalew Haile,Sarah Harrison,Zeinab Hijazi,Phiona Naserian Koyiet,Claire M Whitney,Fahmy Hanna","doi":"10.1016/s2215-0366(26)00050-7","DOIUrl":"https://doi.org/10.1016/s2215-0366(26)00050-7","url":null,"abstract":"","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"13 1","pages":"287-288"},"PeriodicalIF":64.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147490049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Embodied delusions in the cultural-ecosocial niche.","authors":"Wei-Hsiang Liao","doi":"10.1016/s2215-0366(26)00052-0","DOIUrl":"https://doi.org/10.1016/s2215-0366(26)00052-0","url":null,"abstract":"","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"27 1","pages":"287"},"PeriodicalIF":64.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147490051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Joint statement by the World Psychiatric Association, the American Psychiatric Association, the European Psychiatric Association, and the Global Expert Task Force on ECT on the portrayal of electroconvulsive therapy in the WHO Guidance on Mental Health Policy and Strategic Action Plans","authors":"David Zilles-Wegner, Danuta Wasserman, Thomas G Schulze, Oliver Pogarell, Theresa Miskimen, Mark H Rapaport, Paul Summergrad, Andrea Fiorillo, Celso Arango, Global Expert Task Force on ECT, Alexander Sartorius","doi":"10.1016/s2215-0366(26)00059-3","DOIUrl":"https://doi.org/10.1016/s2215-0366(26)00059-3","url":null,"abstract":"The World Psychiatric Association, the American Psychiatric Association, the European Psychiatric Association, and the Global Expert Task Force on ECT welcome the WHO's emphasis on rights-based, person-centered, and recovery-oriented mental health policies. However, they express concern that the WHO Guidance contains scientifically inaccurate and misleading statements particularly regarding electroconvulsive therapy (ECT). These portray ECT as inherently dangerous and advocate for its restriction or prohibition, thereby reinforcing stigma and potentially limiting access to evidence-based care for severely ill patients. Substantial scientific evidence shows that ECT is an effective, safe, and well-tolerated treatment, supported by decades of research and international clinical guidelines. Although acknowledging global variations in regulation and access, the associations stress that denying ECT in life-threatening situations, including in children and adolescents or in patients who lack decision-making capacity, would be unethical. The authors call on WHO to integrate robust scientific evidence and lived experience into future guidance.","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"2 1","pages":""},"PeriodicalIF":64.3,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147587621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Setting priorities for research in addiction","authors":"Anne Lingford-Hughes, Toto Gronlund, Eilish Gilvarry, James Lind Alliance Priority Setting Partnership for Addiction","doi":"10.1016/s2215-0366(26)00023-4","DOIUrl":"https://doi.org/10.1016/s2215-0366(26)00023-4","url":null,"abstract":"","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"15 1","pages":""},"PeriodicalIF":64.3,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147587622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to Lancet Psychiatry 2026; 13: 140–61","authors":"","doi":"10.1016/s2215-0366(26)00094-5","DOIUrl":"https://doi.org/10.1016/s2215-0366(26)00094-5","url":null,"abstract":"<em>Schuster AM, Alwan NA, Callard F, et al. The implications of the COVID-19 pandemic for clinical mental health care.</em> Lancet Psychiatry <em>2026;</em> 13: <em>140–61</em>—In this Series paper, Prof Eric Yu Hai Chen, Prof Stephani L Hatch, Prof Ayana Jordan, and Prof Martin Knapp's professorships were not listed. This correction has been made to the online version as of March 26, 2026.","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"31 1","pages":""},"PeriodicalIF":64.3,"publicationDate":"2026-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147519136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}