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Improving mental health care in Iran 改善伊朗的精神卫生保健
IF 64.3 1区 医学
Lancet Psychiatry Pub Date : 2025-04-24 DOI: 10.1016/s2215-0366(25)00104-x
Rahim Badrfam, Atefeh Zandifar
{"title":"Improving mental health care in Iran","authors":"Rahim Badrfam, Atefeh Zandifar","doi":"10.1016/s2215-0366(25)00104-x","DOIUrl":"https://doi.org/10.1016/s2215-0366(25)00104-x","url":null,"abstract":"No Abstract","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"8 1","pages":""},"PeriodicalIF":64.3,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143872855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bridging gaps in autism spectrum disorder care 弥合自闭症谱系障碍护理方面的差距
IF 64.3 1区 医学
Lancet Psychiatry Pub Date : 2025-04-24 DOI: 10.1016/s2215-0366(25)00093-8
Ajeng Ayu Widiastuti, Adi Atmoko, Nur Eva, Eunike Milasari Listyaningrum, Trivena Dyah Wijayanti
{"title":"Bridging gaps in autism spectrum disorder care","authors":"Ajeng Ayu Widiastuti, Adi Atmoko, Nur Eva, Eunike Milasari Listyaningrum, Trivena Dyah Wijayanti","doi":"10.1016/s2215-0366(25)00093-8","DOIUrl":"https://doi.org/10.1016/s2215-0366(25)00093-8","url":null,"abstract":"No Abstract","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"136 1","pages":""},"PeriodicalIF":64.3,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143872646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A novel discovery platform for targeted drug repurposing: application for psychiatric disorders 靶向药物再利用的新发现平台：精神疾病的应用
IF 64.3 1区 医学
Lancet Psychiatry Pub Date : 2025-04-23 DOI: 10.1016/s2215-0366(25)00066-5
Michael Berk, Jee Hyun Kim, Lana J Williams, Zoe S J Liu, Dan Siskind, Bruna Panizzutti, Alison R Yung, Ken Walder
{"title":"A novel discovery platform for targeted drug repurposing: application for psychiatric disorders","authors":"Michael Berk, Jee Hyun Kim, Lana J Williams, Zoe S J Liu, Dan Siskind, Bruna Panizzutti, Alison R Yung, Ken Walder","doi":"10.1016/s2215-0366(25)00066-5","DOIUrl":"https://doi.org/10.1016/s2215-0366(25)00066-5","url":null,"abstract":"Existing pharmacotherapies and psychotherapies are often inadequate, and discovery for new pharmacological treatments in psychiatry is slow. Existing pharmacotherapies are, however, often inadequate. Few truly novel pharmacotherapies have emerged in the past four decades, largely due to the absence of a known pathophysiology for each disorder. In this Personal View, we describe the platform we have adopted that enables targeted drug repurposing. With this approach, patient-derived stem cells are used to detect transcriptomic targets to identify existing drugs that address these targets. These drugs are then validated in non-human animal models and pharmacoepidemiological studies before being tested in clinical trials. Our targeted drug repurposing platform bypasses the absence of known pathophysiology. Validation steps bring greater scientific rigour and mechanistic insights to drug repurposing to allow only drug candidates with the strongest mechanistic evidence to be tested in clinical trials.","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"17 6 1","pages":""},"PeriodicalIF":64.3,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143866274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
LGBTQ+ mental health in the wake of USA politics LGBTQ+在美国政治之后的心理健康
IF 64.3 1区 医学
Lancet Psychiatry Pub Date : 2025-04-23 DOI: 10.1016/s2215-0366(25)00096-3
Matthew J Mimiaga, Elizabeth A Yonko
{"title":"LGBTQ+ mental health in the wake of USA politics","authors":"Matthew J Mimiaga, Elizabeth A Yonko","doi":"10.1016/s2215-0366(25)00096-3","DOIUrl":"https://doi.org/10.1016/s2215-0366(25)00096-3","url":null,"abstract":"No Abstract","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"69 1","pages":""},"PeriodicalIF":64.3,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143866275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Priorities for addressing mental health conditions and substance use disorders in prisons in sub-Saharan Africa: expert consensus from a Delphi panel 解决撒哈拉以南非洲监狱精神健康状况和药物使用障碍的优先事项：德尔菲小组专家共识
IF 64.3 1区 医学
Lancet Psychiatry Pub Date : 2025-04-15 DOI: 10.1016/s2215-0366(25)00067-7
Helen E Jack, Aish Lovett, Hiwot Weldemariam, Atalay Alem, Serge Dali, Sakios Muduma, Murugi Micheni, Letitia Pienaar, Charlene Sunkel, Zoë Senter, Maryia Shaban, Lydia Chwastiak, Sarah Walker, Adegboyega Ogunwale
{"title":"Priorities for addressing mental health conditions and substance use disorders in prisons in sub-Saharan Africa: expert consensus from a Delphi panel","authors":"Helen E Jack, Aish Lovett, Hiwot Weldemariam, Atalay Alem, Serge Dali, Sakios Muduma, Murugi Micheni, Letitia Pienaar, Charlene Sunkel, Zoë Senter, Maryia Shaban, Lydia Chwastiak, Sarah Walker, Adegboyega Ogunwale","doi":"10.1016/s2215-0366(25)00067-7","DOIUrl":"https://doi.org/10.1016/s2215-0366(25)00067-7","url":null,"abstract":"People who are incarcerated in Africa are not a focus of global mental health research, and incarceration is absent from many international mental health guidelines. Given the dearth of knowledge and services, priorities for research and practice should be established. The Delphi method was used to identify priority challenges related to mental health and substance use disorders among people who are incarcerated in sub-Saharan Africa. Experts in the field completed four iterative electronic surveys. The first survey was an open-ended question about priorities. In subsequent surveys participants used a Likert scale to rate the importance of each priority. 97 experts from 27 countries (20 in sub-Saharan Africa) completed the first survey (64% of those targeted). The 38 priority challenges fell into ten thematic areas: pathways for care during incarceration; the health-care workforce; alternatives to incarceration; the specific needs of women; acute conditions; involvement of non-health-care staff; policy; infrastructure and carceral conditions conditions; re-entry into the community; and people awaiting trial. These priority challenges can guide the efforts of practitioners, policy makers, and researchers to address mental health conditions and substance use disorders among people in prisons in sub-Saharan Africa. Investment in the health-care workforce, policies, and prison infrastructure, as well as developing non-carceral solutions, are needed to support behavioural health in people who are incarcerated.","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"1 1","pages":""},"PeriodicalIF":64.3,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143836859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does ADHD treatment inefficacy question its diagnostic validity? ADHD治疗无效是否质疑其诊断有效性？
IF 64.3 1区 医学
Lancet Psychiatry Pub Date : 2025-04-15 DOI: 10.1016/s2215-0366(25)00045-8
Gin S Malhi, Kinga Szymaniak, Erica Bell
{"title":"Does ADHD treatment inefficacy question its diagnostic validity?","authors":"Gin S Malhi, Kinga Szymaniak, Erica Bell","doi":"10.1016/s2215-0366(25)00045-8","DOIUrl":"https://doi.org/10.1016/s2215-0366(25)00045-8","url":null,"abstract":"No Abstract","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"110 1","pages":""},"PeriodicalIF":64.3,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143836864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bipolar depression management needs randomised controlled trial evidence 双相抑郁症的治疗需要随机对照试验证据
IF 64.3 1区 医学
Lancet Psychiatry Pub Date : 2025-04-15 DOI: 10.1016/s2215-0366(25)00087-2
Chien Cheng, Tien-Wei Hsu, Yu-Chen Kao, Mu-Hong Chen, Chih-Sung Liang
{"title":"Bipolar depression management needs randomised controlled trial evidence","authors":"Chien Cheng, Tien-Wei Hsu, Yu-Chen Kao, Mu-Hong Chen, Chih-Sung Liang","doi":"10.1016/s2215-0366(25)00087-2","DOIUrl":"https://doi.org/10.1016/s2215-0366(25)00087-2","url":null,"abstract":"No Abstract","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"218 1","pages":""},"PeriodicalIF":64.3,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143836867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does ADHD treatment inefficacy question its diagnostic validity? – Authors' reply ADHD治疗无效是否质疑其诊断有效性？-作者回复
IF 64.3 1区 医学
Lancet Psychiatry Pub Date : 2025-04-15 DOI: 10.1016/s2215-0366(25)00088-4
Edoardo G Ostinelli, Andrea Cipriani, Samuele Cortese
{"title":"Does ADHD treatment inefficacy question its diagnostic validity? – Authors' reply","authors":"Edoardo G Ostinelli, Andrea Cipriani, Samuele Cortese","doi":"10.1016/s2215-0366(25)00088-4","DOIUrl":"https://doi.org/10.1016/s2215-0366(25)00088-4","url":null,"abstract":"No Abstract","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"2 1","pages":""},"PeriodicalIF":64.3,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143836865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bipolar depression management needs randomised controlled trial evidence – Authors' reply 双相抑郁症的治疗需要随机对照试验证据——作者回复
IF 64.3 1区 医学
Lancet Psychiatry Pub Date : 2025-04-15 DOI: 10.1016/s2215-0366(25)00089-6
Cagatay Ermis, Heidi Taipale, Jari Tiihonen
{"title":"Bipolar depression management needs randomised controlled trial evidence – Authors' reply","authors":"Cagatay Ermis, Heidi Taipale, Jari Tiihonen","doi":"10.1016/s2215-0366(25)00089-6","DOIUrl":"https://doi.org/10.1016/s2215-0366(25)00089-6","url":null,"abstract":"No Abstract","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"2 1","pages":""},"PeriodicalIF":64.3,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143836866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accurate prevalence estimates needed for youth common mental disorders – Authors' reply 需要对青少年常见精神障碍进行准确的患病率估计——作者的答复
IF 64.3 1区 医学
Lancet Psychiatry Pub Date : 2025-04-15 DOI: 10.1016/s2215-0366(25)00090-2
Ellie M Robson, Susan M Sawyer
{"title":"Accurate prevalence estimates needed for youth common mental disorders – Authors' reply","authors":"Ellie M Robson, Susan M Sawyer","doi":"10.1016/s2215-0366(25)00090-2","DOIUrl":"https://doi.org/10.1016/s2215-0366(25)00090-2","url":null,"abstract":"No Abstract","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"66 1","pages":""},"PeriodicalIF":64.3,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143836863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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