Anaesthesia Critical Care & Pain Medicine最新文献

{"title":"Optimal brain perfusion pressure derived from the continuous monitoring of cerebral autoregulation status during neonatal heart surgery under cardiopulmonary bypass in relation to brain injury: An observational study","authors":"Pierre Bourgoin ,&nbsp;Erta Beqiri ,&nbsp;Peter Smielewski ,&nbsp;Alexis Chenouard ,&nbsp;Aurélie Gaultier ,&nbsp;Flavie Sadones ,&nbsp;Ugo Gouedard ,&nbsp;Nicolas Joram ,&nbsp;Pascal Amedro","doi":"10.1016/j.accpm.2025.101509","DOIUrl":"10.1016/j.accpm.2025.101509","url":null,"abstract":"<div><h3>Background</h3><div>Understanding cerebral blood flow regulation and later optimizing brain perfusion is part of neuroprotection during cardiopulmonary bypass (CPB) in neonates.</div></div><div><h3>Methods</h3><div>A total of 38 neonates undergoing CPB were monitored using near-infrared spectrometry and mean arterial pressure (MAP). Cerebral autoregulation (CAR) was assessed through the continuous measurement of the Cerebral Oxygenation Index (COx), and CAR-derived metrics were determined by plotting averaged COx values by MAP: Optimal MAP (MAPopt), lower limit of CAR (LLA), upper limit of CAR (ULA).</div></div><div><h3>Results</h3><div>Out of 38, 17 (45%) neonates exhibited moderate to severe brain lesions post-operatively. The onset of CPB was associated with CAR disruption (mean COx pre-CPB = 0.16 ± 0.11; during CPB: 0.39 ± 0.37, <em>p</em> &lt; 0.001). A LLA was identified in 31 out of 38 (82%), 23 out of 38 (61%), and 14 out of 38 (37%) patients before, during, and after CPB, respectively. An ULA was identified in 29 out of 38 (76%), 22 out of 38 (58%), and 14 out of 38 (37%) patients in the same time frames. Patients with abnormal post-operative brain MRI spent more time below the LLA during CPB: 28.3% [17.1–32.9] <em>versus</em> 9.9% [6.9–18.5] in patients without detected brain injury, <em>p</em> = 0.039. No differences were observed regarding the time spent above the upper limit of autoregulation.</div></div><div><h3>Conclusion</h3><div>The study provides valuable insights into the intricate relationship between intraoperative cerebral hemodynamics and post-operative brain injury. Further research is warranted to explore potential interventions based on CAR-derived metrics during CPB in neonates.</div></div><div><h3>Clinical trial registration number</h3><div>Not applicable.</div></div><div><h3>Prior presentation</h3><div>Not applicable.</div></div>","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":"44 3","pages":"Article 101509"},"PeriodicalIF":3.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative analysis of patient and family satisfaction in Spanish Intensive Care Units: A cross-sectional study of the impact of diagnosis","authors":"Eva de Miguel-Balsa ,&nbsp;Esther Rios-Albert ,&nbsp;Beatriz Quevedo-Sánchez ,&nbsp;Angela Jorda-Miñana ,&nbsp;Cristina Portillo-Requena ,&nbsp;Sonia Perez-Quesada ,&nbsp;Elena Alfaro-Garcia ,&nbsp;Adoración Alcalá-López","doi":"10.1016/j.accpm.2025.101515","DOIUrl":"10.1016/j.accpm.2025.101515","url":null,"abstract":"<div><h3>Background</h3><div>Analysing relatives and patients experiences and satisfaction can highlight areas for improving Intensive Care Units (ICUs) care. Patients and families may differ about satisfaction and experience, depending on the diagnosis and procedures. We aimed to compare the experience and satisfaction of patients according to diagnosis, severity, and the procedures received, and also between relatives and patients.</div></div><div><h3>Methods</h3><div>Prospective analysis of voluntary responses to the FS (Family Satisfaction)- ICU 24 R questionnaire from surviving ICU patients and their relatives (January-April 2023) in four Spanish hospitals, according to diagnostic groups. Responses were scored on a Likert scale (0: worst score; 100: best score), and means and standard deviations were compared.</div></div><div><h3>Results</h3><div>185 responses were analysed, mostly acute cardiac pathology patients (91, 50.83%), followed by septic shock patients (22.9%). Patients rated the team performance higher than their relatives (98.79 ± 5.37 vs 89.68 ± 18.43; <em>p</em> &lt; 0.0001), also symptom management such as pain (95.62 ± 9.52 vs 89.64 ± 17.24; p = 0.0001, and dyspnoea (94.23 ± 12.27 vs 88.09 ± 17.87; <em>p</em> = &lt;0.001), the information process (91.50 ± 13.43 vs 83.17 ± 21.00; p &lt; 0.001), and decision-making (80.38 ± 13.60 vs 65.84 ± 23.60; <em>p</em> &lt; 0.001). Patients found visits to be scarce (43.75 ± 20.79), although their families were satisfied with their involvement in care (85.49 ± 19.64). Patients with sepsis and septic shock rated pain management the lowest compared to other diagnostic groups (sepsis/septic shock 89.58 ± 12.5 vs 98.61 ± 5.89; <em>p</em> &lt; 0.001).</div></div><div><h3>Conclusions</h3><div>Open visiting policies and enhancing the protocols for conscious sedation/analgesia in invasive procedures are opportunities to improve the satisfaction and experience of ICU patients and their families.</div></div>","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":"44 3","pages":"Article 101515"},"PeriodicalIF":3.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143895269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Norepinephrine infusion for preventing hypotension during hepatic exteriorization in Kasai portoenterostomy in infants with biliary atresia: A randomized controlled trial","authors":"Khaled Sarhan,&nbsp;Nehal Ashraf,&nbsp;Ahmed Hasanin,&nbsp;Marwa Zayed,&nbsp;Reham Saleh,&nbsp;Manal Elgohary,&nbsp;Ramy Alkonaiesy,&nbsp;Kareem Nawwar","doi":"10.1016/j.accpm.2025.101519","DOIUrl":"10.1016/j.accpm.2025.101519","url":null,"abstract":"<div><h3>Background</h3><div>Hepatic exteriorization during Kasai portoenterostomy is usually associated with profound hypotension. This study aimed to assess the role of prophylactic norepinephrine infusion in maintaining blood pressure in infants undergoing Kasai portoenterostomy operation.</div></div><div><h3>Methods</h3><div>Thirty-two infants scheduled for Kasai portoenterostomy operation were randomly assigned to one of two groups: Norepinephrine group: this group received prophylactic intraoperative norepinephrine infusion, Control group: this group received placebo saline infusion. The primary outcome was the incidence of hypotension during liver exteriorization, defined as a persistent reduction of the mean arterial pressure (MAP) ≥20% of the baseline reading requiring release of the liver. Other outcomes included: the frequency of stoppage of surgery and release of the liver, liver function variables, arterial blood gases parameters, total volume of intraoperative infused fluids, and incidence of bradycardia and hypertension.</div></div><div><h3>Results</h3><div>The incidence of persistent hypotension (defined as the need for liver release after administering IV fluid and vasopressor boluses) during liver exteriorization, was 12.5% (2 patients) in the norepinephrine group compared to 75% (12 patients) in the control group, relative risk (95% confidence interval [CI]): 0.17 (0.04−0.63), <em>p</em> =  0.001. Rescue norepinephrine boluses were used in 3 patients (18.8%) in the norepinephrine group compared to 13 patients (81.3%) in the control group, relative risk (95% CI): 0.23 (0.08−0.66), <em>p</em> =  0.001.</div></div><div><h3>Conclusion</h3><div>Among infants with biliary atresia undergoing Kasai portoenterostomy operation, norepinephrine infusion significantly reduced the incidence of persistent severe hypotension during hepatic exteriorization requiring liver release.</div></div><div><h3>Clinical trial identifier</h3><div><span><span>NCT05521152</span><svg><path></path></svg></span>.</div></div><div><h3>Registration URL</h3><div><span><span>https://clinicaltrials.gov/study/NCT05521152</span><svg><path></path></svg></span>.</div></div>","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":"44 3","pages":"Article 101519"},"PeriodicalIF":3.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143903374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Post-induction hypotension during rapid sequence intubation in the operating room: A post hoc analysis of the randomized controlled REMICRUSH trial","authors":"Nicolas Grillot ,&nbsp;Victoire Gonzalez ,&nbsp;Romain Deransy ,&nbsp;Armine Rouhani ,&nbsp;Guillaume Cintrat ,&nbsp;Paul Rooze ,&nbsp;Edouard Naux ,&nbsp;Christelle Volteau ,&nbsp;Marwan Bouras ,&nbsp;Raphael Cinotti ,&nbsp;Antoine Roquilly","doi":"10.1016/j.accpm.2025.101502","DOIUrl":"10.1016/j.accpm.2025.101502","url":null,"abstract":"<div><h3>Background</h3><div>We explored the risk factors of post-induction hypotension during rapid sequence intubation.</div></div><div><h3>Methods</h3><div>We performed an ancillary analysis of a multicenter randomized clinical trial comparing remifentanil <em>versus</em> neuromuscular blockers associated with hypnotic in patients at risk for aspiration who underwent tracheal intubation in the operating room. The primary outcome was post-induction hypotension, defined as an episode of hypotension (MBP ≤ 55 mmHg and/or SBP ≤ 80 mmHg) within 10 min after anesthetic induction.</div></div><div><h3>Results</h3><div>From 15 hospitals, 1137 adult patients were included, and 291 (26%) had post-induction hypotension. Propofol was used in 1117 (98%) patients and was associated with low doses of ketamine in 209 (18 %) patients. The independent risk factors associated with post-induction hypotension were age (OR 1.03, 95% CI [1.02; 1.04] <em>p</em> &lt; 0.0001), baseline heart rate (<em>p</em> = 0.0068), bowel occlusion requiring nasogastric tube placement before intubation (OR 1.96, 95% CI [1.33; 2.87] <em>p</em> = 0.0006) and use of remifentanil (OR 3.54, 95%CI (2.61; 4.81) <em>p</em> &lt; 0.0001). Use of low doses of ketamine (OR 0.61, 95% CI [0.41; 0.92] <em>p</em> = 0.0175) and basal SBP (OR 0.98, 95% CI [0.97; 0.99] <em>p</em> &lt; 0.0001) were protective factors. The precision of the final model including the above-mentioned variables gave an AUC of 0.74 [95% CI 0.71; 0.77] for post-induction hypotension prediction.</div></div><div><h3>Conclusions</h3><div>Post-induction hypotension was frequent during rapid sequence intubation. Sedation associating propofol with low doses of ketamine was associated with a low risk of post-induction hypotension. Further studies are required to demonstrate a causal effect.</div></div><div><h3>Registration</h3><div>ClinicalTrials.gov NCT03960801</div></div>","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":"44 3","pages":"Article 101502"},"PeriodicalIF":3.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adjuvant nefopam versus standard of care in mechanically ventilated surgical critically ill patients: A randomized, double-blind controlled study","authors":"Mohammed Gamal Abdelraouf ,&nbsp;Samar Farghali Farid ,&nbsp;Ahmed Mohammed Mukhtar ,&nbsp;Nirmeen Ahmed Sabry","doi":"10.1016/j.accpm.2025.101518","DOIUrl":"10.1016/j.accpm.2025.101518","url":null,"abstract":"<div><h3>Background</h3><div>Multimodal analgesia, through combining different classes of analgesia that target pain pathways with different mechanisms reduces opioid consumption. This study aimed to determine the impact of adjunct nefopam infusion on opiate consumption when added to standard-of-care analgesia and sedation in mechanically ventilated critically ill patients.</div></div><div><h3>Methods</h3><div>This was a prospective, randomized, active control, double-blind study. Patients admitted to the ICU, being mechanically ventilated and candidates for analgesia and sedation protocols were randomized to the intervention group (<em>n</em> = 30) or to the control group (<em>n</em> = 30).</div><div>The primary outcome was the cumulative dose of fentanyl in the first 24 h after inclusion. The secondary outcomes were the proportion of patients with positive pain scores, change in mean arterial pressure (MAP), heart rate (HR), ICU mortality, and others.</div></div><div><h3>Results</h3><div>A total of 60 patients were included in the final analysis; median (Q1, Q3) cumulative fentanyl consumption mcg/24 h was significantly (<em>p</em> = 0.001) lower in the intervention group compared to the control group 1300 (575, 2087.5) <em>vs.</em> 2400 (1612.5, 2665) mcg/24 h respectively. Pain and sedation scores were comparable between the two study groups. ICU mortality was 25 (83.3%) in the intervention group <em>vs</em>. 20 (66.7%) in the control group (<em>P</em> = 0.136).</div></div><div><h3>Conclusions</h3><div>Nefopam was found to be an effective non-opioid option for analgesia in mechanically ventilated surgical and trauma critically ill patients, and more studies are needed to evaluate its safety.</div></div><div><h3>Clinical trial registry and number</h3><div><span><span>ClinicalTrials.gov</span><svg><path></path></svg></span> (identifier: <span><span>NCT05071352</span><svg><path></path></svg></span>).</div></div>","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":"44 3","pages":"Article 101518"},"PeriodicalIF":3.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143904496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The sodium-glucose cotransporter 2 inhibitors in perioperative and intensive care settings","authors":"Marc-Olivier Fischer ,&nbsp;Pierre-Grégoire Guinot","doi":"10.1016/j.accpm.2025.101511","DOIUrl":"10.1016/j.accpm.2025.101511","url":null,"abstract":"","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":"44 3","pages":"Article 101511"},"PeriodicalIF":3.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early extubations in children intubated prior to arrival in Paediatric Burn ICU: A single center retrospective study over 1520 admissions","authors":"Sébastien Lebrun ,&nbsp;Nicolas Louvet ,&nbsp;Nada Sabourdin ,&nbsp;Isabelle Constant","doi":"10.1016/j.accpm.2025.101500","DOIUrl":"10.1016/j.accpm.2025.101500","url":null,"abstract":"<div><h3>Background</h3><div>In adult burns intensive care units, more than 30% of patients arriving intubated, are extubated within 2 days (potentially unnecessary intubation, PUNI). Such data are lacking in paediatric populations. Exploring this paediatric PUNI rate was the primary aim of the study.</div></div><div><h3>Methods</h3><div>Data from all the admissions to our paediatric burn intensive care unit were retrospectively analyzed over an 8-years period. Extubations within the first two days among patients arriving intubated were assessed as the primary outcome (PUNI rate). Using a univariate logistic regression and a multivariate model, we analyzed factors associated with intubation lasting more than 2 days (potentially necessary intubation, PNI). Finally, we developed a score to predict the probability of PNI.</div></div><div><h3>Results</h3><div>Among the 1520 admitted children (age: 0–17; Percentage of Total Body Surface Area (%TBSA): 1%–97%), 56 (4%) arrived intubated, 20 (36%) of whom were considered PUNI. These patients had smaller %TBSA burned compared to those having PNI (24% ± 17% <em>vs</em>. 48% ± 24%, <em>p</em> = 0.002). We developed a score based on factors independently associated with PNI: %TBSA burned (OR = 1.12 [1.09–1.15] for each additional per cent), flame burns (OR = 4.43 [1.64–11.6]) and facial burns (OR = 12.28 [3.41–67.4]). Seven children (&lt;0.5%) were intubated after admission.</div></div><div><h3>Conclusion</h3><div>Intubation before admission to a burn intensive care unit was less frequent in children. The paediatric rate of PUNI, however, was close to findings reported in adults: approximately one-third of intubated children were extubated within 2 days.</div></div>","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":"44 3","pages":"Article 101500"},"PeriodicalIF":3.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Weaning from external ventricular drainage after non-traumatic subarachnoid hemorrhage: Rapid vs. gradual weaning and predicting closure trial failure. The SEVDVE retrospective multicenter cohort study","authors":"Henri Lomo ,&nbsp;Joseph Brasselet ,&nbsp;Hélène Gohel ,&nbsp;Simon Praud ,&nbsp;Vincent Roux ,&nbsp;Julie Faule ,&nbsp;Tiphaine Bernard ,&nbsp;Karim Lakhal ,&nbsp;Yoann Launey ,&nbsp;Etienne Botquelen ,&nbsp;Claire Dahyot-Fizelier ,&nbsp;Antoine Roquilly ,&nbsp;Maeva Campfort ,&nbsp;Maxime Leger ,&nbsp;Sigismond Lasocki ,&nbsp;for ATLANREA study Group","doi":"10.1016/j.accpm.2025.101508","DOIUrl":"10.1016/j.accpm.2025.101508","url":null,"abstract":"<div><h3>Background</h3><div>Weaning from external ventricular drainage (EVD) following subarachnoid hemorrhage (SAH) typically requires an EVD closure trial, performed either straightforwardly (rapid weaning) or after gradual elevation of EVD (gradual weaning). We wanted to compare these two methods and build a sore to predict closure trial failure.</div></div><div><h3>Methods</h3><div>Among adult SAH patients, this multicenter (<em>n</em> = 5) retrospective study, compared rapid and gradual EVD weaning methods, and identified factors associated with EVD closure trial failure through logistic regressions. We developed a score to predict closure trial failure by splitting the dataset into training (2/3) and testing (1/3) sets.</div></div><div><h3>Results</h3><div>Among 1141 patients with an EVD between 01/01/2018 and 12/31/2022, 407 were hospitalized for SAH and had at least one EVD weaning attempt, 249 (61%) underwent gradual and 158 (39%) rapid weaning. Rapid weaning was associated with more failure (72 (46%) <em>vs.</em> 86 (35%), <em>p</em> = 0.044), but shorter length of stay (LOS) in both ICU and hospital. EVD closure trial failure was independently associated with prolonged EVD maintenance (<em>p</em> &lt; 0.001), prolonged ICU (<em>p</em> = 0.001) and hospital LOS (<em>p</em> = 0.05). We developed a failure closure score using the difference in intracranial pressures (from H0 to H3 after closure), time since EVD insertion, and EVD level. The model’s area under the receiver operating curve was 0.63 [0.53–0.74], indicating fair discrimination ability.</div></div><div><h3>Conclusions</h3><div>EVD weaning strategies vary across centres. Rapid weaning was associated with a high risk of closure trial failure, but shorter LOS. EVD closure trial failure was associated with worse outcomes. A simple 3-criteria score could help.</div></div>","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":"44 3","pages":"Article 101508"},"PeriodicalIF":3.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Promoting sustainability within intensive care nursing: Ten tips for environmental responsibility","authors":"Matthieu Bernat ,&nbsp;Heather Baid ,&nbsp;David Grimaldi ,&nbsp;Laurent Zieleskiewicz","doi":"10.1016/j.accpm.2025.101506","DOIUrl":"10.1016/j.accpm.2025.101506","url":null,"abstract":"","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":"44 2","pages":"Article 101506"},"PeriodicalIF":3.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reversing aminosteroid neuromuscular blocking drugs with sugammadex — Pipecuronium, rocuronium and vecuronium are not the same","authors":"Andrew Bowdle,&nbsp;Stephan R. Thilen","doi":"10.1016/j.accpm.2025.101496","DOIUrl":"10.1016/j.accpm.2025.101496","url":null,"abstract":"","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":"44 2","pages":"Article 101496"},"PeriodicalIF":3.7,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}