Anaesthesia Critical Care & Pain Medicine最新文献

{"title":"Finding the right balance - not just papering over the cracks. A broader system change is required not quotas alone.","authors":"Britta S von Ungern-Sternberg, Aine Sommerfield, Esther Pogatzki-Zahn, Karin Becke-Jakob","doi":"10.1016/j.accpm.2026.101970","DOIUrl":"https://doi.org/10.1016/j.accpm.2026.101970","url":null,"abstract":"","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":" ","pages":"101970"},"PeriodicalIF":5.4,"publicationDate":"2026-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149372005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraoperative desaturation: the anesthesiologist's routine, research's blind spot.","authors":"Martin Ruste, Aaron D Aguirre, Anaïs Caillard","doi":"10.1016/j.accpm.2026.101971","DOIUrl":"https://doi.org/10.1016/j.accpm.2026.101971","url":null,"abstract":"","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":" ","pages":"101971"},"PeriodicalIF":5.4,"publicationDate":"2026-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149372006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Authors reply.","authors":"Elettra Merola, Maria Pina Dore","doi":"10.1016/j.accpm.2026.101980","DOIUrl":"https://doi.org/10.1016/j.accpm.2026.101980","url":null,"abstract":"","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":" ","pages":"101980"},"PeriodicalIF":5.4,"publicationDate":"2026-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149358182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on: \"Enhanced Recovery after Distal Radius Fracture Surgery using Combined Short- and Long-Acting Nerve Blocks: A Randomized Controlled Trial\".","authors":"Chang Liu, Xue Chen, Hui Liu","doi":"10.1016/j.accpm.2026.101986","DOIUrl":"https://doi.org/10.1016/j.accpm.2026.101986","url":null,"abstract":"","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":" ","pages":"101986"},"PeriodicalIF":5.4,"publicationDate":"2026-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149358184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postoperative pain management: a national prospective study including 3879 patients.","authors":"Emile Daurel, Raïko Blondonnet, Olivier Ruinet, Benoit Vandenbunder, Cécile Faulcon, Marion Lebon, Sébastien Campard, Tommy Raveau, Julien De Guis, Frédéric Aubrun, Guillaume Rousseau, Florent Saintot, Philippe Cuvillon, Fabrice Ferre, Frédéric Adam, Jamie Elmawieh, Georges Daccache, Benjamin Brodaty, Aurélia Henin, Emilie Ellies, Jean-Charles Muller, Antoine Astier, Matthias Garot, Mehdi Henry, Martin Bonnassieux, Marie-Odile Roussat, Zanaidou Issa, Nathalie Douet, Nicolas Rocq, Bertrand Dousset, Franck Verdonk, Johannes Wolter, Vincent Royon, Sandrine Lopez, Clément Bouvet, Morgana Jeantieu, Paul Sacquin, Mathieu Fontaine, Sacha Meimoun, Marie Keyser, Ingrid Millot, Gilles Lebuffe, Augustin Schaefer, Stéphanie Sigaut, Alexandre Di Marco, Thibaut Pranal, Alexandre Uk Hel Chau, Mourad Lakhdari, Loïc Lefebvre, Jennifer Thinnes Rocher, Baptiste Trolonge, Christel Di Falco, Raghida Joseph, Elisa Klapka, Paul Vangreveninge, Mathilde Vernet, Grégoire Barthel, Morgane Brusc, Gilles Dawance, Marie-Madeleine Maintenant, Atanas Yavashev, Fabienne Teneur, Dimitri Verheeke, Sylvie Arnold, Gergana Nikolova, Tarik Arab, Sylvie Vrignaud, Charlotte Lacroix, Didier Lahitte, SeverineLaforet, Stefanie Koessler, Marine Coroir, Mohamed Adel, Axelle Eugene, Fabrice Daviaud, Marc Solier, Eklu Vossah, Chafia Daoui, Chloé Rousseau, Helene Beloeil, Pauline Rouxel","doi":"10.1016/j.accpm.2026.101977","DOIUrl":"https://doi.org/10.1016/j.accpm.2026.101977","url":null,"abstract":"<p><strong>Background: </strong>Postoperative pain management remains a critical issue in peri-operative medicine, but contemporary national data are lacking.</p><p><strong>Methods: </strong>AlgoSFAR 2 was a prospective, multicentre and observational study, conducted in randomly selected French surgical centres. Adult patients undergoing elective surgery were included. Pain was assessed at rest and during mobilization over the first three postoperative days. Secondary outcomes included postoperative opioid consumption and multimodal analgesia strategies defined as the use of at least two non-opioid strategies such as analgesics and/or regional anaesthesia.</p><p><strong>Results: </strong>A total of 3879 patients from 80 centres were analysed. While pre-operative and immediate postoperative pain levels at rest were low, pain peaked on day 1, with high interindividual variability, and 6% of patients reported severe pain. Two thirds (66%) did not need any rescue opioids postoperatively. Overall, 95% received multimodal analgesia.</p><p><strong>Conclusion: </strong>These results highlight a major change in postoperative pain management in France, with broad adoption of multimodal opioid-sparing strategies. Nonetheless, a minority of patients still experience severe pain, highlighting the need for personalized management.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov NCT06487442.</p>","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":" ","pages":"101977"},"PeriodicalIF":5.4,"publicationDate":"2026-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149358186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Population pharmacokinetics of fibrinogen in postpartum haemorrhage during Caesarean section: a secondary analysis of the TRACES trial.","authors":"Maxence Hureau, Julien Lanoiselée, Emilien Abraham, Bérangère Denys, Oliver Lukowiak, Emmanuelle Jeanpierre, Sophie Susen, Edouard Ollier, Anne-Sophie Bouthors","doi":"10.1016/j.accpm.2026.101958","DOIUrl":"https://doi.org/10.1016/j.accpm.2026.101958","url":null,"abstract":"<p><strong>Background: </strong>In severe postpartum haemorrhage (PPH), hypofibrinogenaemia is strongly associated with bleeding severity. To correct fibrinogen depletion, various fixed dosing regimens have been evaluated, but the optimal fibrinogen dosing regimen remains unknown. To date, fibrinogen pharmacokinetics have only been studied outside haemorrhagic settings (healthy or afibrinogenaemic patients) METHODS: This ancillary analysis of the TRACES trial assessed fibrinogen kinetics in 142 women with PPH > 800 ml during caesarean section, among which 31 received fibrinogen replacement. Plasma fibrinogen concentrations (n = 593) were measured using the Clauss method. A population pharmacokinetic model was developed using nonlinear mixed-effects modeling. Simulations were performed to estimate loading and maintenance doses required to achieve target fibrinogen concentrations.</p><p><strong>Results: </strong>A one-compartment logistic model adequately described plasma fibrinogen levels. Bleeding rate was identified as a key covariate to explain fibrinogen loss rate. Based on the estimated model, an optimised dosing regimen was derived to achieve and maintain predefined target fibrinogen levels. To achieve a target increase of 1 g.L^-¹ in plasma fibrinogen level, the required fibrinogen loading dose is at least 2.7 g for a body weight of 50 kg. To maintain plasma fibrinogen level at a target of 2 g.L^-¹ during a 1000 mL.h^-¹ bleeding rate, a fibrinogen infusion rate of 0.9 g.h^-¹ would be required.</p><p><strong>Conclusions: </strong>This work supports that an individualized target-controlled fibrinogen dosing strategy is probably required to effectively correct fibrinogen levels. Integrating such models as a clinical decision support tool into a multimodal strategy that also utilizes viscoelastic testing could optimize PPH management.</p>","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":" ","pages":"101958"},"PeriodicalIF":5.4,"publicationDate":"2026-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149358185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Associations of Pain, Analgesia Technique, and Psychological Factors with Central Sensitization after Childbirth\".","authors":"Sachin Kumar, Nirupma Gupta, Sujeet Kumar Singh, Hariharan Srinivasan, Varshini Vadhithala, Sushma Narsing Katkuri, Brajgopal Kushwaha","doi":"10.1016/j.accpm.2026.101983","DOIUrl":"https://doi.org/10.1016/j.accpm.2026.101983","url":null,"abstract":"","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":" ","pages":"101983"},"PeriodicalIF":5.4,"publicationDate":"2026-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149358183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibiotic prophylaxis in pancreaticoduodenectomy after biliary drainage: should local ecology and perioperative factors guide practice?","authors":"Hugo Doucet, Ahmet Ayav, Sandrine Henard, Marie-Reine Losser, Emmanuel Novy","doi":"10.1016/j.accpm.2026.101985","DOIUrl":"https://doi.org/10.1016/j.accpm.2026.101985","url":null,"abstract":"","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":" ","pages":"101985"},"PeriodicalIF":5.4,"publicationDate":"2026-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149358180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor: \"General Anesthesia Versus Non-General Anesthesia in Young Adults Undergoing Thrombectomy\".","authors":"Yu-Chen Huang, Chih-Yao Chiang, Cheng-Wei Lu","doi":"10.1016/j.accpm.2026.101979","DOIUrl":"https://doi.org/10.1016/j.accpm.2026.101979","url":null,"abstract":"","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":" ","pages":"101979"},"PeriodicalIF":5.4,"publicationDate":"2026-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149344154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to Comment on \"Associations of Pain, Analgesia Technique, and Psychological Factors with Central Sensitization after Childbirth\".","authors":"Shaohong Wang, Rehena Sultana, Chin Wen Tan, Ban Leong Sng","doi":"10.1016/j.accpm.2026.101982","DOIUrl":"https://doi.org/10.1016/j.accpm.2026.101982","url":null,"abstract":"","PeriodicalId":48762,"journal":{"name":"Anaesthesia Critical Care & Pain Medicine","volume":" ","pages":"101982"},"PeriodicalIF":5.4,"publicationDate":"2026-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149344157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}