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Clinics in Colon and Rectal Surgery最新文献

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Corrigendum: Current Position of Sacral Neuromodulation in Treatment of Fecal Incontinence. 更正：骶神经调控在治疗大便失禁中的当前地位。
IF 1.2 4区 医学
Clinics in Colon and Rectal Surgery Pub Date : 2024-07-20 eCollection Date: 2021-01-01 DOI: 10.1055/s-0044-1788698
Binit Katuwal, Jasneet Bhullar
{"title":"Corrigendum: Current Position of Sacral Neuromodulation in Treatment of Fecal Incontinence.","authors":"Binit Katuwal, Jasneet Bhullar","doi":"10.1055/s-0044-1788698","DOIUrl":"https://doi.org/10.1055/s-0044-1788698","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1055/s-0040-1714247.].</p>","PeriodicalId":48754,"journal":{"name":"Clinics in Colon and Rectal Surgery","volume":"34 1","pages":"e1"},"PeriodicalIF":1.2,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11260210/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141735436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current Trends in the Management of a Complex Polyp: Endoscopy versus Surgery 复杂息肉治疗的当前趋势：内镜与手术
IF 1.4 4区 医学
Clinics in Colon and Rectal Surgery Pub Date : 2024-07-03 DOI: 10.1055/s-0044-1787892
Mahnoor Khan, Kavel Visrodia, Amrita Sethi
{"title":"Current Trends in the Management of a Complex Polyp: Endoscopy versus Surgery","authors":"Mahnoor Khan, Kavel Visrodia, Amrita Sethi","doi":"10.1055/s-0044-1787892","DOIUrl":"https://doi.org/10.1055/s-0044-1787892","url":null,"abstract":"<p>Many colorectal cancers arise from either adenomatous polyps or sessile serrated lesions. However, due to the implementation of screening guidelines at the age of 45 years and the ability to perform therapeutic endoscopic polyp resections, the incidence and mortality of colorectal cancer has been decreasing in the United States. Polyps can be distinguished not only by pathology, but characterized by their complexity depending on the size, location, and morphology. Historically, polyps that were endoscopically more challenging to resect were referred for surgical resection. However, due to rapid advancement in endoscopic techniques and availability of tools, many of these complex polyps can be safely and effectively resected endoscopically. In this section, we review the different methods and potential challenges associated with endoscopic resection techniques including endoscopic mucosal resection, endoscopic submucosal dissection, or endoscopic full-thickness resection of a complex polyp.</p> ","PeriodicalId":48754,"journal":{"name":"Clinics in Colon and Rectal Surgery","volume":"61 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141548570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hereditary Colorectal Cancer: From Diagnosis to Surgical Options 遗传性结直肠癌：从诊断到手术选择
IF 1.4 4区 医学
Clinics in Colon and Rectal Surgery Pub Date : 2024-07-03 DOI: 10.1055/s-0044-1787884
Rami James N. Aoun, Matthew F. Kalady
{"title":"Hereditary Colorectal Cancer: From Diagnosis to Surgical Options","authors":"Rami James N. Aoun, Matthew F. Kalady","doi":"10.1055/s-0044-1787884","DOIUrl":"https://doi.org/10.1055/s-0044-1787884","url":null,"abstract":"<p>Hereditary colorectal cancer (CRC) syndromes account for up to 5% of CRC. Patients have an increased risk of CRC and extracolonic cancers, both of which develop at an early age. The main polyposis syndromes include familial adenomatous polyposis, MYH-associated polyposis, Peutz-Jeghers syndrome, juvenile polyposis syndrome, and PTEN hamartoma syndrome. The non-polyposis syndromes include Lynch syndrome and familial colorectal cancer type X. Each of the syndromes have distinct but sometimes overlapping phenotypes. Clinical evaluation and ultimately the underlying germline genetic pathogenic variants define the syndromes. Each syndrome has polyp, CRC, and extracolonic risks and management is based on early and timely surveillance with therapeutic and often extended prophylactic surgery. Surgical intervention strategies are individualized, considering not only the earlier onset of malignancies and heightened risks for metachronous cancers but also the patient's needs and quality of life. This article reviews the different diagnostic approaches to hereditary CRC and highlights subsequent disease-specific management and surgical decision-making strategies.</p> ","PeriodicalId":48754,"journal":{"name":"Clinics in Colon and Rectal Surgery","volume":"31 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141548571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Young: Early-Onset Colon Cancer 年轻人早期结肠癌
IF 1.4 4区 医学
Clinics in Colon and Rectal Surgery Pub Date : 2024-07-02 DOI: 10.1055/s-0044-1787883
David Cohen, Caitlin Rogers, Joel Gabre, Beatrice Dionigi
{"title":"The Young: Early-Onset Colon Cancer","authors":"David Cohen, Caitlin Rogers, Joel Gabre, Beatrice Dionigi","doi":"10.1055/s-0044-1787883","DOIUrl":"https://doi.org/10.1055/s-0044-1787883","url":null,"abstract":"<p>Early-onset colorectal cancer (EO-CRC), characterized by diagnosis before the age of 50 years, has emerged as a significant healthcare challenge with increasing global incidence. While traditional risk factors such as family history and inherited syndromes contribute to EO-CRC, a substantial proportion of cases remain sporadic, necessitating further investigation into additional etiological factors. Molecular studies reveal heterogeneity in EO-CRC, with distinct mutational profiles compared to late-onset CRC. Clinical management presents unique considerations, including challenges in early detection and treatment strategies tailored to younger patients. Addressing EO-CRC requires a multidisciplinary approach integrating epidemiological, molecular, and clinical insights to improve prevention, diagnosis, and therapeutic outcomes. Emerging research avenues explore novel biomarkers and therapeutic targets, offering promise for advancing understanding and management of this disease in contemporary oncology practice.</p> ","PeriodicalId":48754,"journal":{"name":"Clinics in Colon and Rectal Surgery","volume":"39 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141530601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Old: Is There Any Role for Screening Colonoscopy after the Age of 75? The Surgeon's Perspective 老年人75 岁以后还需要进行结肠镜筛查吗？外科医生的视角
IF 1.4 4区 医学
Clinics in Colon and Rectal Surgery Pub Date : 2024-06-27 DOI: 10.1055/s-0044-1787893
Imran Khan, Mikhael Belkovsky, Emre Gorgun
{"title":"The Old: Is There Any Role for Screening Colonoscopy after the Age of 75? The Surgeon's Perspective","authors":"Imran Khan, Mikhael Belkovsky, Emre Gorgun","doi":"10.1055/s-0044-1787893","DOIUrl":"https://doi.org/10.1055/s-0044-1787893","url":null,"abstract":"<p>Guidelines recommend individualized decision making for screening colonoscopy for colorectal cancer (CRC) in patients after the age of 75 years due to low additional benefits. That should be taken with a grain of salt, as these recommendations are based on expert opinion and simulation models which do not consider (1) the differences in pathogenesis and cancer biology of CRC in elderly; (2) the risks of colonoscopy in this patient population; (3) and the impact of new surgical and nonsurgical therapies for CRC. In this review, our goal is to bring a surgeon's perspective to understand the role of screening colonoscopy in patients older than 75 years.</p> ","PeriodicalId":48754,"journal":{"name":"Clinics in Colon and Rectal Surgery","volume":"3 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141502493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Colon Cancer and Pregnancy 结肠癌与怀孕
IF 1.4 4区 医学
Clinics in Colon and Rectal Surgery Pub Date : 2024-06-26 DOI: 10.1055/s-0044-1787890
Olivia A. Sacks, Jennifer S. Davids
{"title":"Colon Cancer and Pregnancy","authors":"Olivia A. Sacks, Jennifer S. Davids","doi":"10.1055/s-0044-1787890","DOIUrl":"https://doi.org/10.1055/s-0044-1787890","url":null,"abstract":"<p>As the incidence of colorectal cancer (CRC) in the younger population increases and women start their childbearing journey at later ages, CRC in pregnancy will become an increasingly relevant and decreasingly rare occurrence. Unfortunately, there is a dearth of data on this subject given its historical rarity. CRC is often diagnosed at a late stage in pregnancy because of the conflation of symptoms of pregnancy with symptoms of CRC. A major branch point for the diagnosis and treatment of CRC in pregnancy is whether it is diagnosed early or late in pregnancy. The workup for cancer is similar for pregnant and nonpregnant populations and includes endoscopy and staging computed tomography. Treatment is dependent on the stage of cancer and term of pregnancy. This review summarizes the current evidence for diagnosis, workup, and treatment of CRC during pregnancy and explores issues of fertility after a diagnosis of CRC.</p> ","PeriodicalId":48754,"journal":{"name":"Clinics in Colon and Rectal Surgery","volume":"79 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2024-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141502494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systemic Therapy for Metastatic Colon Cancer: New Frontiers 转移性结肠癌的系统疗法：新领域
IF 1.4 4区 医学
Clinics in Colon and Rectal Surgery Pub Date : 2024-06-25 DOI: 10.1055/s-0044-1787826
Yoanna S. Pumpalova
{"title":"Systemic Therapy for Metastatic Colon Cancer: New Frontiers","authors":"Yoanna S. Pumpalova","doi":"10.1055/s-0044-1787826","DOIUrl":"https://doi.org/10.1055/s-0044-1787826","url":null,"abstract":"<p>We have made steady gains in improving overall survival in patients with metastatic, unresectable, colon cancer in the last 5 to 10 years. The backbone of systemic treatment for most patients remains combination chemotherapy, but the field is becoming increasingly biomarker driven, with exciting new targeted therapies on the horizon. This review is organized in sections corresponding to currently relevant biomarkers in colon cancer and will summarize first-, second-, and third-line standard of care for metastatic, unresectable, colon cancer. The last section is intended to introduce the reader to promising agents and novel therapeutic strategies currently under investigation.</p> ","PeriodicalId":48754,"journal":{"name":"Clinics in Colon and Rectal Surgery","volume":"36 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141502497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Colorectal Cancer and Inflammatory Bowel Disease 大肠癌和炎症性肠病
IF 1.4 4区 医学
Clinics in Colon and Rectal Surgery Pub Date : 2024-06-24 DOI: 10.1055/s-0044-1787891
Maysoon Gamaleldin, Taha Qazi, Tracy Hull
{"title":"Colorectal Cancer and Inflammatory Bowel Disease","authors":"Maysoon Gamaleldin, Taha Qazi, Tracy Hull","doi":"10.1055/s-0044-1787891","DOIUrl":"https://doi.org/10.1055/s-0044-1787891","url":null,"abstract":"<p>Colorectal cancer (CRC) in patients with ulcerative colitis (UC) and Crohn's disease accounts for ∼5% of all cases of CRC. Although it only accounts for a fraction of CRC cases, inflammatory bowel disease (IBD)-related CRC is a serious consequence of chronic inflammation that needs attention. There is a better understanding today about the pathogenesis contributing to IBD-CRC and the role of genetics and gut microbiota. Guidelines recommend timely screening and surveillance of UC and Crohn's patients, and it is usually timed from the initial diagnosis. This helps with early detection of dysplasia and CRC in this subset of patients, thus allowing for earlier intervention. However, dysplasia is not always easy to discern and management of CRC in each patient may differ. A multidisciplinary approach should be adopted in managing CRC in IBD. Although the oncologic principles of managing sporadic CRC and IBD-CRC are the same, surgical resection should be tailored to each patient.</p> ","PeriodicalId":48754,"journal":{"name":"Clinics in Colon and Rectal Surgery","volume":"19 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141502496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Ugly: Metastatic Colon Cancer—Surgical Options 丑陋转移性结肠癌--手术选择
IF 1.4 4区 医学
Clinics in Colon and Rectal Surgery Pub Date : 2024-06-18 DOI: 10.1055/s-0044-1787825
Fahima Dossa, Martin R. Weiser
{"title":"The Ugly: Metastatic Colon Cancer—Surgical Options","authors":"Fahima Dossa, Martin R. Weiser","doi":"10.1055/s-0044-1787825","DOIUrl":"https://doi.org/10.1055/s-0044-1787825","url":null,"abstract":"<p>Over 50% of patients with colorectal cancer develop metastatic disease. Although systemic therapy remains the backbone of palliative treatment, select patients may be candidates for surgical resection with curative intent. Given increasing evidence of the association between metastasectomy and prolonged survival, surgery has acquired an increasingly central role in the management of liver, lung, and peritoneal metastases. This is compounded by accumulating advances in local and systemic treatments that have allowed for expansion of the resectability pool, bringing the potential for curative surgical treatment to increasing numbers of patients with stage IV disease. However, as the boundaries of resectability are pushed, patient selection and consideration of tumor-related and technical factors are imperative to the identification of patients for whom surgery would be of the greatest benefit.</p> ","PeriodicalId":48754,"journal":{"name":"Clinics in Colon and Rectal Surgery","volume":"5 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2024-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141502498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Closing the Gap: Approaches to Improving Colorectal Surgery Care for the Uninsured and Underinsured 缩小差距：改善无保险和保险不足人群结直肠外科护理的方法
IF 1.4 4区 医学
Clinics in Colon and Rectal Surgery Pub Date : 2024-05-15 DOI: 10.1055/s-0044-1786398
Erin Isenberg, Calista Harbaugh
{"title":"Closing the Gap: Approaches to Improving Colorectal Surgery Care for the Uninsured and Underinsured","authors":"Erin Isenberg, Calista Harbaugh","doi":"10.1055/s-0044-1786398","DOIUrl":"https://doi.org/10.1055/s-0044-1786398","url":null,"abstract":"<p>Health insurance plays a critical role in access to and delivery of health care in the United States. As the only industrialized nation without universal health coverage, Americans without adequate insurance (i.e., uninsured or underinsured individuals) face numerous obstacles to obtaining necessary health care. In this article, we review the mechanisms by which inadequate insurance leads to worse clinical outcomes in patients with common benign and malignant colorectal pathologies. We then discuss several evidence-based solutions for improving access to optimal colorectal care for these patients. These include increasing access to and affordability of health insurance, mitigating disparities between differently insured populations, strengthening the health care safety net, and tailoring outreach and clinical decision-making for the uninsured and underinsured. By exploring the nuance and impact of inadequate insurance coverage, we ultimately seek to highlight critical opportunities for future research and advocacy within the realm of insurance design and policy.</p> ","PeriodicalId":48754,"journal":{"name":"Clinics in Colon and Rectal Surgery","volume":"27 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141059996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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