憩室病的结构改变。

IF 1.1 4区医学 Q4 GASTROENTEROLOGY & HEPATOLOGY

Clinics in Colon and Rectal Surgery Pub Date : 2024-10-10 eCollection Date: 2025-07-01 DOI:10.1055/s-0044-1791283

Kerri Lopez, Lillias H Maguire

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引用次数: 0

摘要

当使用结肠镜导航狭窄、成角的结肠或在手术中切除僵硬、固定的乙状结肠时，临床医生重视憩室疾病的结构改变。对这些组织的检查显示平滑肌厚度增加，细胞外基质的数量和结构发生改变，结肠的运动性发生变化。现在，更复杂的技术使科学家能够解开这些变化与个体遗传背景之间的联系。本文探讨了憩室病的结构改变，包括胶原蛋白、平滑肌、肠神经系统和Cajal间质细胞。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Structural Alterations in Diverticular Disease.

Clinicians appreciate the structural alterations of diverticular disease when navigating narrow, angulated colons with a colonoscope or removing stiff, fixed sigmoid colons at surgery. Investigation of these tissues reveals increased thickness of smooth muscle, alterations in the amount and structure of the extracellular matrix, and changes to the motility of the colon. More sophisticated technologies now allow scientists to unravel the connections between these alterations and the individual genetic background. This article explores the structural alterations of diverticular disease including collagen, smooth muscle, the enteric nervous system, and the interstitial cells of Cajal.

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来源期刊

Clinics in Colon and Rectal Surgery GASTROENTEROLOGY & HEPATOLOGYSURGERY-SURGERY

CiteScore

2.60

自引率

7.10%

发文量

期刊介绍： Clinics in Colon and Rectal Surgery is a review journal that publishes topic-specific issues on diseases of the small bowel, colon, rectum, and anus. Designed for clinicians, researchers, and educators involved with diseases of the intestinal tract, the journal covers a broad spectrum of basic information, controversial clinical issues, and established and innovative diagnostic techniques. Issue topics comprehensively cover the entire specialty over a 3-4 year period, allowing the articles to serve as study material for educational programs and certifying examinations. The inclusion of research and clinical material also allows physicians to remain knowledgeable of current advances in the specialty.