Lancet Hiv最新文献

{"title":"Correction to Lancet HIV 2025; 12: e616–26","authors":"","doi":"10.1016/s2352-3018(26)00037-8","DOIUrl":"https://doi.org/10.1016/s2352-3018(26)00037-8","url":null,"abstract":"","PeriodicalId":48725,"journal":{"name":"Lancet Hiv","volume":"16 1","pages":""},"PeriodicalIF":16.1,"publicationDate":"2026-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147278862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Post-mortem characterisation of HIV-associated under-5 deaths in the CHAMPS network: population-based mortality surveillance","authors":"Inacio Mandomando, Zachary J Madewell, Portia C Mutevedzi, Kitiezo Aggrey Igunza, Dickens Onyango, Emily A Rogena, Joyce Were, Tacilta Nhampossa, David Torres-Fernandez, Rosauro Varo, Elisio G Xerinda, Ziyaad Dangor, Shabir A Madhi, Sana Mahtab, Gillian Sorour, Megan Dempster, Sulaiman Lakoh, Soter Ameh, Ikechukwu Udo Ogbuanu, Julius Ojulong, Solomon Samura, Adama Mamby Keita, Karen L Kotloff, Diakaridia Sidibe, Samba O Sow, Milagritos D Tapia, Nega Assefa, Daniel Demessie, Lola Madrid, J Anthony G Scott, Getahun Wakwaya, Shams El Arifeen, Emily S Gurley, Beth A Tippett Barr, Cynthia G Whitney, Dianna M Blau, Quique Bassat, Victor Akelo, Fatima Solomon, Hennie Lombaard, Jeannette Wadula, Karen Petersen, Martin Hale, Nelesh P. Govender, Peter J. Swart, Sanjay G. Lala, Sithembiso Velaphi, Richard Chawana, Yasmin Adam, Amy Wise, Nellie Myburgh, Sanwarul Bari, Shahana Parveen, Mohammed Kamal, A.S.M. Nawshad Uddin Ahmed, Mahbubul Hoque, Saria Tasnim, Ferdousi Islam, Farida Ariuman, Mohammad Mosiur Rahman, Ferdousi Begum, Mustafizur Rahman, Dilruba Ahmed, Meerjady Sabrina Flora, Tahmina Shirin, Mahbubur Rahman, Joseph Oundo, Alexander M. Ibrahim, Fikremelekot Temesgen, Tadesse Gure, Addisu Alemu, Melisachew Mulatu Yeshi, Mahlet Abayneh Gizaw, Stian MS Orlien, Solomon Ali, Peter Otieno, Peter Nyamthimba Onyango, Janet Agaya, Richard Oliech, Dickson Gethi, George Aol, Thomas Misore, Harun Owuor, Christopher Muga, Bernard Oluoch, Christine Ochola, Sharon M. Tennant, Carol L. Greene, J. Kristie Johnson, Brigitte Gaume, Rima Koka, Karen D. Fairchild, Diakaridia Kone, Doh Sanogo, Uma U. Onwuchekwa, Nana Kourouma, Seydou Sissoko, Cheick Bougadari Traore, Jane Juma, Kounandji Diarra, Awa Traore, Tiéman Diarra, Kiranpreet Chawla, Zara Manhique, Sibone Mocumbi, Clara Menéndez, Khátia Munguambe, Ariel Nhacolo, Maria Maixenchs, Andrew Moseray, Fatmata Bintu Tarawally, Martin Seppeh, Ronald Mash, Babatunde Duduyemi, James Bunn, Alim Swaray-Deen, Joseph Bangura, Amara Jambai, Margaret Mannah, Okokon Ita, Cornell Chukwuegbo, Princewill Nwajiobi, Dickens Kowuor, Erick Kaluma, Oluseyi Balogun, Carrie Jo Cain, Samuel Pratt, Francis Moses, Tom Sesay, James Squire, Joseph Kamanda Sesay, Osman Kaykay, Binyam Halu, Hailemariam Legesse, Francis Smart, Sartie Kenneh","doi":"10.1016/s2352-3018(25)00330-3","DOIUrl":"https://doi.org/10.1016/s2352-3018(25)00330-3","url":null,"abstract":"","PeriodicalId":48725,"journal":{"name":"Lancet Hiv","volume":"18 1","pages":""},"PeriodicalIF":16.1,"publicationDate":"2026-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147278873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hope for every child: ending paediatric HIV mortality by 2030","authors":"Irene Njuguna, Grace John-Stewart","doi":"10.1016/s2352-3018(26)00003-2","DOIUrl":"https://doi.org/10.1016/s2352-3018(26)00003-2","url":null,"abstract":"","PeriodicalId":48725,"journal":{"name":"Lancet Hiv","volume":"51 1","pages":""},"PeriodicalIF":16.1,"publicationDate":"2026-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147278861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recommendations from the 2nd Consensus Workshop on Analytical Treatment Interruption in HIV Research Trials","authors":"Prof Thumbi Ndung'u PhD, Krista L Dong MD, Donn J Colby MD, Prof Steven G Deeks MD, Prof Mark F Cotton MD, Karine Dubé DrPH, Prof Philip J Goulder MD, Boris Julg MD, Moses Nsubuga, Gbolahan Ajibola MD, Katharine J Bar MD, Nomonde Bengu MD, Mutsa Bwakura-Dangarembizi PhD, Prof Marina Caskey MD, Gabriela Cromhout MD, Adeodata R Kekitiinwa MBChB, William Kilembe MBChB, Prof Louise Kuhn PhD, Udom Likhitwonnawut BA, Nyaradzo M Mgodi MBChB, Prof Deborah Persaud MD, Michael J Peluso MD, Thomas A Rasmussen MD, Matthew Romo PharmD, Carlo Sacdalan MD, Wadzanai Samaneka MD, Prof Roger Shapiro MD, Ole S Søgaard MD, Prof Gareth Tudor-Williams MBBS, Charity Wambui MBChB, Randall Tressler MD, Prof Sharon R Lewin MD, Trevor A Crowell MD, Victoria O Kasprowicz PhD, Lydie Trautmann PhD, 2nd ATI Consensus Workshop","doi":"10.1016/s2352-3018(25)00373-x","DOIUrl":"https://doi.org/10.1016/s2352-3018(25)00373-x","url":null,"abstract":"Analytical treatment interruption (ATI) is an important tool to evaluate interventions designed to achieve HIV eradication or long-term control without antiretroviral therapy. We convened a stakeholder workshop to update the published recommendations for the conduct of ATI studies. Important changes to the recommendations include more lenient entry criteria on CD4 count, CD4 nadir, and past medical history, and allowance for greater variation based on regional standards. As the mechanism of potential HIV remission might rely on immune control, the criteria for antiretroviral therapy resumption now allow for longer periods of viraemia at higher levels to stimulate a more robust immune response. Greater emphasis is placed on the importance of psychosocial monitoring and support, the prevention of HIV transmission to partners during ATI, and the integration of sociobehavioural research into ATI studies. Recommendations for the conduct of paediatric and adolescent ATI trials, absent from previous guidelines, are now included. These recommendations, based on current available data, expert opinion, and community consultation, aim to help steer the safe and ethical implementation of the next generation of ATI trials as we continue the search for an HIV cure.","PeriodicalId":48725,"journal":{"name":"Lancet Hiv","volume":"17 1","pages":""},"PeriodicalIF":16.1,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147278229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-acting PrEP and equitable HIV prevention in Brazil","authors":"Silvia Maria da Silva Sant'Ana Rodrigues, Lucindo José Quintans-Júnior, Adriano Antunes de Souza Araújo, Paulo Ricardo Martins-Filho","doi":"10.1016/s2352-3018(26)00029-9","DOIUrl":"https://doi.org/10.1016/s2352-3018(26)00029-9","url":null,"abstract":"","PeriodicalId":48725,"journal":{"name":"Lancet Hiv","volume":"128 1","pages":""},"PeriodicalIF":16.1,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147278228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and immunogenicity of a single dose of Ad26.COV2.S, BNT162b2, or SARS-CoV-2-rS-protein-nanoparticle in previously vaccinated and unvaccinated adults living with and without HIV in South Africa: a phase 2a randomised, observer-blind trial","authors":"Vaneshree Govender, Tarylee Reddy, Pholo Maenetje, Trevor Beattie, Tania Adonis, Tanya Nielson, Jayajothi Moodley, John Mdluli, Aruna Bhoola, Stacey Angelo, Ravindre Panchia, Kathy Mngadi, Craig Innes, William Brumskine, Mandla Mlotshwa, Lindiwe Nhlangulela, Itai Ncube, Thandeka Moyo-Gwete, Penny L Moore, Roanne S Keeton, Wendy Burgers, Kapil Kumar, Neha Garg, Alok Tripathi, Sharfuddin Sayed, Katleho Matsimela, Nobuhle Mchunu, Robert Wallis, Vinodh A Edward, Gavin J Churchyard, Mamothedi Tebatso Tshwana, Keitumetsi Moreki, Zithelo Zikalala, Magotso Pearl Makola, Nondumiso Vester Masango, Precious Nomsa Mofokeng, Louise Pretorius, Mponeng Mathobela Molepo, Fortune Mokhomola, Aifheli Marcia Masevhe, Manasa Mapendere, Mogafe Lucia Mokaba, Hanlie Veldsman, Carita Marx, Amukelani Tshabalala, Malebo Pertunia Mahlalela, Mpho Netshongolwe, Mpho Tshabalala, Letlhogonolo Rosemary Moleoa, Poelano Hope Mashile, Duduzile Gumede, Trisha Munsamy, Mandisa Nkosi, Lindelwa Nkangane, Bonolo Mntungwa, Monicah Thabisile Mbonani, Johan Riaan Jordaan, Maporene Andries Sebopa, Thandiwe Rosemary Maseko, Rose Ntavasi Nkanyane, Jerlyn Benyera, Thompho Mugwena, Emily Kekana, Ephriam Mmalekutu Pilusa, Sizakele Christobel Dlamini, Pardon Kamogelo Kgaladi, Malobisa Sylvester Magwasha, Samkelo Moloi, Themba Phakathi, Tlhago Elias Ngwanto, Dapheney Tiyiselani Mashele, Rirhandzu Pollet Rikhotso, Nhlamulo Baloyi, Christinah Nthathane Nke, Elizabeth Barbara Janse Van Rensburg, Amanda Van Aswegen, Madile Lillian Batsietseng, Mmanare Maria Tlhapi, Oteng Letlape, Tebogo Rampai, Pontsho Motsatse, Nthabiseng Mofube, Lebogang Moletashope, Primrose Mothaga, Precious Lebatsi, Lucky Letlhogonolo Dhlamini, Tshohanyetso Mosoahle, Thelma Goliath, Letlhogonolo Seabela, Seleke Maroo, Thapelo Chele, Marelize Collignon, Adriane Kock, Immaculate Mabasa, James Craig Innes, Thato Cherity Mohlala, Aphiwe Tshwati, Ken Clarke, Nondumiso Langa, Palesa Mosweu, Maditaba Anna Ramokanate, Tshepo Baba, Temoso Masenya, Aneesa Lakhi, Mgcini Moyo, Lezaan-Marie Smit, Kesenogile Baepanye, Welhemina Jonkane, Selvy Samoele Matshego, Thandiwe Papalagae, Busisiwe Xhamagele, Lindiwe Rosetta Nhlangulela, Graciano Market, Obakeng Violet Mokotedi, Nkosinathi Charles Mabuza, Moleboheng Belina Motsiri, Keatlegile Phumlani Motswenyane, Katlego Mooketsi, Masabata Veronica Sekgonyane, Tanya Nielson, Marthinette Taljaard, William Lawrence Brumskine, Ni Ni Sein, Tiro Amos Dinake, Phillip Mafori Mphahlele, Siyabonga Nhlapo, Ireen Lesebang Mosweu, Lesego Lucky Molosiwa, Themba Phakathi, Chantal Onkgopotse Molotsi, Kabelo Mabeleng, Gloria Keitumetse Kolobe, Patient Madidimalo Machaba, Dipuo Sebese, Mabika Christian Kasongo, Sifiso Cornelius Shezi, Caroline Mokhoko, Karabo Believer Morebodi, Tshegofatso Dorah Moloatsi, Lethabo Colleen Theko, Ellen Matsane, Mando Mmakhora Thaba, Lerato Julia Block, Seasebeng Pertunia Mothobi, Perfect Tiisetso Malope, Tshegofatso Magnus Ramatlhape, Precy Mashele, Gloria Mmoge Mataboge, Joan Nyanghongo, Emilia de Klerk, Banyana Olga Motlagomang, Kgomotso Abegail Mokotedi, Nisha Naidoo, Rendani Helen Ngwagwe, Susan Vermaak, Sefolo Moses Kgaphola, Bonolo Pearl Mabebe, Melissa Neo Senne, Brenda Modisaotsile, Kgothatso Precious Tau, Engela du Plooy, Aluwani Adolf Thovhakale, Kamogelo Fortunate Matlhase, Mmarona Elizabeth Lekalakala, Boikago Lekotloane Lekalakala, Boitumelo Modisaotsile, Likhapha Monica Pule, Esme Venter, Zwelethu Zwane, Nicole Glover, Liezl Nel, Henriette Bam, Innocent Shibambo, Queen Thaba, Nkateko Maringa, Rebaona Legoale, Molebogeng Nkete, Tsholofelo Moagi, Thilivhali Mulaudzi, Thandeka Mpontshane, Dinah Pambo, Refiloe Masemola, Mandisa Nyanya, Kathryn Therese Mngadi, Anja Nanine Henning, Mashudu Brian Mahlangu, Sabiha Shaik, Rujeko Mashingaidze, Yajna Duki, Sibekezelo Msomi, Tshiamo Moela, Calvin Kgaphol, Kgopotso Mojela, Nomagugu Sibanda, Abram Nhlapo, Thando Mkhaliphi, Zanele Rachel Skosana, Nolwazi Mahlangu, Mashudu Siebani, Pule Msibi, Vincent Tshikovhi, Sizakele Christobel Dlamini, Happiness Thulile Mthalane, Elia Motwanama, Elliot Lesiba Ramokolo, Sindisiwe Sibiya, Nontsikelelo Hamnca, Zandiswa Kula, Nelisa Mboto, Bontle Mapoma, Dineo Rammutla, Nthabiseng Khoza, Pardon Kamogelo Kgaladi, Tumelo Moorosi, Moyahabo Faith Molapo, Tshifaro Nedzingahe, Busisiwe Mpila, Khuthadzo Hlongwane, Emily Lebotsa, Paballo Mosala, Maxine A Höft, Millicent A Omondi, Rofhiwa Nesamari, Ntombi Benede, Richard Baguma, Asiphe S Besethi, Siyabulela FJ Magugu, Amkele Ngomti, Anathi A Nkayi, Avril Walters, Sashkia R Balla, Qiniso Mkhize, Anbalagan Anantharaj, Parveen Singh, Pooja Kumari Shashi, Akshita Garg, Josephine H Cox, Wayne C Koff, Rym Ben Othman, Arnaud Marchant, Coralie Henin, John Altin, Heather Mead, Erin Kelley, Phillip Felgner, Rie Nakajima, Rafael Ramiro De Assis","doi":"10.1016/s2352-3018(25)00275-9","DOIUrl":"https://doi.org/10.1016/s2352-3018(25)00275-9","url":null,"abstract":"","PeriodicalId":48725,"journal":{"name":"Lancet Hiv","volume":"85 1","pages":""},"PeriodicalIF":16.1,"publicationDate":"2026-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146160437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety, acceptability, and adherence to dapivirine vaginal ring and oral pre-exposure prophylaxis for HIV prevention in the second trimester of pregnancy: a multicountry, open-label, phase 3b randomised trial","authors":"Felix G Mhlanga, Daniel W Szydlo, Ashley J Mayo, Katherine Bunge, Lee Fairlie, Clemensia Nakabiito, Petina Musara, Nyaradzo M Mgodi, Sufia Dadabhai, Rachel Scheckter, Peter L Anderson, Mark A Marzinke, Catherine Chappell, Luis A Gadama, Barbra A Richardson, Jeanna M Piper, Sharon L Hillier, Bonus Makanani, Luis Gadama, Linly Seyama, Taha E Taha, Mary Glenn Fowler, Carlotta Mabuza, Hermien Gous, Petina Musara, Z. Mike Chirenje, Naana Cleland, Roberta Black, Nahida Chakhtoura, Dianne M Rausch, Teri Senn, James F Rooney, Zeda Rosenberg, Craig Hendrix, Lisa Noguchi, Abraham Johnson, Cheryl Blanchette, Jontraye Davis, Tara McClure, Lisa Levy, Richard H. Beigi, Sharon A Riddler, Devika Singh, Edward Livant, Lisa Rossi, Luis Duran, Mei Song, Ariana Katz, Alinda Young, Elizabeth Montgomery, Imogen Hawley, Marie Stoner, Ariane van der Straten, Ivan Balan, Barbra Richardson, Jennifer Balkus, Lena Kemel, Maricel Manalo, Tanya Harrell, Amanda Brown","doi":"10.1016/s2352-3018(25)00307-8","DOIUrl":"https://doi.org/10.1016/s2352-3018(25)00307-8","url":null,"abstract":"","PeriodicalId":48725,"journal":{"name":"Lancet Hiv","volume":"394 1","pages":""},"PeriodicalIF":16.1,"publicationDate":"2026-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146152769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preventing tuberculosis in advanced HIV disease","authors":"Rubeshan Perumal, Kogieleum Naidoo","doi":"10.1016/s2352-3018(25)00277-2","DOIUrl":"https://doi.org/10.1016/s2352-3018(25)00277-2","url":null,"abstract":"","PeriodicalId":48725,"journal":{"name":"Lancet Hiv","volume":"304 1","pages":""},"PeriodicalIF":16.1,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146134183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inpatient initiation of tuberculosis preventive therapy with 1 month of isoniazid and rifapentine for adults with advanced HIV disease and cryptococcal meningitis (IMPROVE): a non-inferiority, randomised controlled trial","authors":"Jayne Ellis, Gila Hale, Laura J Nsangi, Abduljewad Wele, Enos Kigozi, Jane Gakuru, Enock Kagimu, Timothy Mugabi, Suzan Namombwe, Sarah Kimuda, Faizo Ssekindi, Jane F Ndyetukira, Alisat Sadiq, Asmus Tukundane, Wilber Bakka, Thomas S Harrison, Emmanuel Mande, Conrad Muzoora, David A J Moore, David B Meya, Katherine Fielding, David R Boulware, Joseph N Jarvis","doi":"10.1016/s2352-3018(25)00246-2","DOIUrl":"https://doi.org/10.1016/s2352-3018(25)00246-2","url":null,"abstract":"","PeriodicalId":48725,"journal":{"name":"Lancet Hiv","volume":"92 1","pages":""},"PeriodicalIF":16.1,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146134182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thank you to The Lancet HIV's statistical and peer reviewers in 2025","authors":"","doi":"10.1016/s2352-3018(26)00001-9","DOIUrl":"https://doi.org/10.1016/s2352-3018(26)00001-9","url":null,"abstract":"","PeriodicalId":48725,"journal":{"name":"Lancet Hiv","volume":"17 1","pages":""},"PeriodicalIF":16.1,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146134184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}