Lancet Hiv最新文献

{"title":"Embedding mental health and SRHR in HIV–UHC strategies","authors":"Kaymarlin Govender, Olivier Mukuku, Jesper Sundewall","doi":"10.1016/s2352-3018(26)00030-5","DOIUrl":"https://doi.org/10.1016/s2352-3018(26)00030-5","url":null,"abstract":"","PeriodicalId":48725,"journal":{"name":"Lancet Hiv","volume":"25 1","pages":""},"PeriodicalIF":16.1,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146110019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to Lancet HIV 2025; 12: e616-26.","authors":"","doi":"10.1016/S2352-3018(26)00008-1","DOIUrl":"https://doi.org/10.1016/S2352-3018(26)00008-1","url":null,"abstract":"","PeriodicalId":48725,"journal":{"name":"Lancet Hiv","volume":"13 2","pages":"e84"},"PeriodicalIF":13.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146133400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AI integration into HIV care.","authors":"The Lancet Hiv","doi":"10.1016/S2352-3018(26)00009-3","DOIUrl":"https://doi.org/10.1016/S2352-3018(26)00009-3","url":null,"abstract":"","PeriodicalId":48725,"journal":{"name":"Lancet Hiv","volume":"13 2","pages":"e71"},"PeriodicalIF":13.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146133415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thailand's progress toward long-acting PrEP.","authors":"Rossaphorn Kittiyawamarn, Pongtorn Chatpituck, Phalin Kamolwat, Opass Putcharoen, Anchalee Avihingsanon","doi":"10.1016/S2352-3018(26)00005-6","DOIUrl":"https://doi.org/10.1016/S2352-3018(26)00005-6","url":null,"abstract":"","PeriodicalId":48725,"journal":{"name":"Lancet Hiv","volume":"13 2","pages":"e79-e80"},"PeriodicalIF":13.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146133495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cigarette smoking in PrEP recipients: a challenge and an opportunity","authors":"Jonathan Shuter, Nancy A Rigotti, Krishna P Reddy, Uriel R Felsen, Andrea H Weinberger, Amanda L Graham, Rochelle P Walensky","doi":"10.1016/s2352-3018(25)00372-8","DOIUrl":"https://doi.org/10.1016/s2352-3018(25)00372-8","url":null,"abstract":"","PeriodicalId":48725,"journal":{"name":"Lancet Hiv","volume":"17 1","pages":""},"PeriodicalIF":16.1,"publicationDate":"2026-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146089583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Linguistic equity for inclusive care in HIV guidelines","authors":"Ralph Hurley O'Dwyer, Diego García Rodríguez, Ashwin Delmonte Sen, Giovanni Villa","doi":"10.1016/s2352-3018(25)00334-0","DOIUrl":"https://doi.org/10.1016/s2352-3018(25)00334-0","url":null,"abstract":"","PeriodicalId":48725,"journal":{"name":"Lancet Hiv","volume":"93 1","pages":""},"PeriodicalIF":16.1,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146072277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using art to promote HIV prevention and highlight inequalities","authors":"Tony Kirby","doi":"10.1016/s2352-3018(26)00011-1","DOIUrl":"https://doi.org/10.1016/s2352-3018(26)00011-1","url":null,"abstract":"","PeriodicalId":48725,"journal":{"name":"Lancet Hiv","volume":"36 1","pages":""},"PeriodicalIF":16.1,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146071544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the effectiveness of a depression-integrated model in adult HIV care in Uganda (the HIV+D trial): a cluster-randomised controlled trial.","authors":"Eugene Kinyanda,Leticia Kyohangirwe,Richard S Mpango,Isaac Sekitoleko,Wilber Ssembajjwe,Christine Tusiime,Joshua Ssebunnya,Kenneth Katumba,Barbra Elsa Kiconco,Yoko Laurence,Patrick Tenya,Joy Turyahabwa,Patrick Katana,Ian Ross,Anna Vassall,Giulia Greco,James Mugisha,Geoffrey Taasi,Hafsa Sentongo,Dickens Akena,Wilson W Muhwezi,Helen A Weiss,Melissa Neuman,Birthe L Knizek,Jonathan Levin,Pontiano Kaleebu,Ricardo Araya,Vikram Patel","doi":"10.1016/s2352-3018(25)00232-2","DOIUrl":"https://doi.org/10.1016/s2352-3018(25)00232-2","url":null,"abstract":"BACKGROUNDAlthough depression is common in people with HIV, mental health interventions are not available to the vast majority of people with HIV in Africa. We aimed to test the effectiveness of the HIV+D collaborative stepped care depression intervention in adult HIV care in Uganda.METHODSA cluster-randomised controlled trial was done at 40 randomly selected primary HIV care centres (clusters) at public health-care facilities in three districts in Uganda. The 40 clusters were randomly allocated (1:1) to enhanced usual care only (EUC arm) or to HIV+D intervention plus EUC, with the randomisation stratified by level of health facility. We recruited adults (aged 18 years or older) with HIV with depression, defined by the locally validated version of the Patient Health Questionnaire 9 (PHQ-9). Participants were consecutively recruited into the study clinics until there was a maximum of 30 participants per cluster. HIV+D was coordinated by a lay counsellor and involved four sequential steps of psychoeducation, behavioural activation, antidepressant medication, and referral. EUC comprised sharing screening results with the HIV clinic physician and training on the WHO guidelines for depression management in routine care. The primary outcome was PHQ-9 scores at 3 months. The trial is registered with the ISRCTN registry (ISRCTN86760765) and is completed.FINDINGS8441 people with HIV were referred to the trial, and 1115 (13%) were enrolled between May 3 and Dec 31, 2021. The mean age was 38 years, 859 (77%) were female, 535 were enrolled in the EUC group, and 580 were enrolled in the HIV+D plus EUC group. Primary outcome data were available for 1097 (98%) participants. We observed high levels of fidelity, with 290 (92%) of 316 participants in the HIV+D plus EUC intervention group receiving the recommended 4-10 sessions of behavioural activation. At 3 months, the mean PHQ-9 scores were lower in the HIV+D plus EUC group, at 3middot;0 (SD 3middot;2) compared with the EUC group, at 7middot;6 (SD 4middot;2; adjusted mean difference 4middot;4; 95% CI 3middot;4-5middot;5; p<0middot;0001; effect size [d]=1middot;34). This effect was sustained, although attenuated, at 12 months (adjusted mean difference 1middot;9; 95% CI 1middot;0-2middot;8; p<0middot;0001; d=0middot;81). Baseline depression severity scores moderated the HIV+D plus EUC intervention effect, with the intervention having stronger effects for those with baseline scores in the severe range (≥20) than for those whose scores were in the moderate range (10-19) both at 3 and 12 months (p values for effect modification were <0middot;001 and 0middot;005, respectively). There was no evidence of effect modification by sex nor baseline HIV viral load. One participant in the HIV+D plus EUC group was hospitalised because of severe depression.INTERPRETATIONThe HIV+D plus EUC intervention had a significant and sustained effect on depression compared with EUC. This intervention offers a scalable approach to integrate","PeriodicalId":48725,"journal":{"name":"Lancet Hiv","volume":"85 1","pages":""},"PeriodicalIF":16.1,"publicationDate":"2026-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145994976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"25 years of the Alliance for Public Health in Ukraine.","authors":"Ed Holt","doi":"10.1016/s2352-3018(26)00007-x","DOIUrl":"https://doi.org/10.1016/s2352-3018(26)00007-x","url":null,"abstract":"","PeriodicalId":48725,"journal":{"name":"Lancet Hiv","volume":"15 1","pages":""},"PeriodicalIF":16.1,"publicationDate":"2026-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145994977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lessons from Brazil's elimination of vertical HIV transmission.","authors":"Mauer Alexandre da Ascensão Gonçalves,Humberto Morais,Pedro Dos Reis Sousa E Almeida,Howard Lopes Ribeiro Junior","doi":"10.1016/s2352-3018(26)00002-0","DOIUrl":"https://doi.org/10.1016/s2352-3018(26)00002-0","url":null,"abstract":"","PeriodicalId":48725,"journal":{"name":"Lancet Hiv","volume":"83 1","pages":""},"PeriodicalIF":16.1,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145993048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}