Bio-Design and Manufacturing最新文献_第7页

Bionic lightweight design of limb leg units for hydraulic quadruped robots by additive manufacturing and topology optimization 通过增材制造和拓扑优化，为液压四足机器人设计仿生轻质肢腿单元

IF 7.9 1区医学

Bio-Design and Manufacturing Pub Date : 2023-12-09 DOI: 10.1007/s42242-023-00256-0

Huaizhi Zong, Junhui Zhang, Lei Jiang, Kun Zhang, Jun Shen, Zhenyu Lu, Ke Wang, Yanli Wang, Bing Xu

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引用次数: 1

Transfer film effects induced by 3D-printed polyether-ether-ketone with excellent tribological properties for joint prosthesis 具有优异摩擦学性能的3d打印聚醚酮诱导关节假体转移膜效应

IF 7.9 1区医学

Bio-Design and Manufacturing Pub Date : 2023-11-28 DOI: 10.1007/s42242-023-00258-y

Yang Li, Jibao Zheng, Changning Sun, Dichen Li

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引用次数: 0

A novel integrated microfluidic chip for on-demand electrostatic droplet charging and sorting 一种用于静电液滴按需充电和分选的新型集成微流控芯片

IF 7.9 1区医学

Bio-Design and Manufacturing Pub Date : 2023-11-25 DOI: 10.1007/s42242-023-00257-z

Jinhui Yao, Chunhua He, Jianxin Wang, Canfeng Yang, Ye Jiang, Zhiyong Liu, Guanglan Liao, Tielin Shi

{"title":"A novel integrated microfluidic chip for on-demand electrostatic droplet charging and sorting","authors":"Jinhui Yao, Chunhua He, Jianxin Wang, Canfeng Yang, Ye Jiang, Zhiyong Liu, Guanglan Liao, Tielin Shi","doi":"10.1007/s42242-023-00257-z","DOIUrl":"https://doi.org/10.1007/s42242-023-00257-z","url":null,"abstract":"<p>On-demand droplet sorting is extensively applied for the efficient manipulation and genome-wide analysis of individual cells. However, state-of-the-art microfluidic chips for droplet sorting still suffer from low sorting speeds, sample loss, and labor-intensive preparation procedures. Here, we demonstrate the development of a novel microfluidic chip that integrates droplet generation, on-demand electrostatic droplet charging, and high-throughput sorting. The charging electrode is a copper wire buried above the nozzle of the microchannel, and the deflecting electrode is the phosphate buffered saline in the microchannel, which greatly simplifies the structure and fabrication process of the chip. Moreover, this chip is capable of high-frequency droplet generation and sorting, with a frequency of 11.757 kHz in the drop state. The chip completes the selective charging process via electrostatic induction during droplet generation. On-demand charged microdroplets can arbitrarily move to specific exit channels in a three-dimensional (3D)-deflected electric field, which can be controlled according to user requirements, and the flux of droplet deflection is thereby significantly enhanced. Furthermore, a lossless modification strategy is presented to improve the accuracy of droplet deflection or harvest rate from 97.49% to 99.38% by monitoring the frequency of droplet generation in real time and feeding it back to the charging signal. This chip has great potential for quantitative processing and analysis of single cells for elucidating cell-to-cell variations.</p><h3 data-test=\"abstract-sub-heading\">Graphic abstract</h3>\u0000","PeriodicalId":48627,"journal":{"name":"Bio-Design and Manufacturing","volume":"32 1","pages":""},"PeriodicalIF":7.9,"publicationDate":"2023-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138534680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biomanufacturing in Japan: frontier research from 2018 to 2023 日本生物制造:2018 - 2023年前沿研究

1区医学

Bio-Design and Manufacturing Pub Date : 2023-11-07 DOI: 10.1007/s42242-023-00261-3

Qing Cao, Yangqianhui Zhang, Runyi Deng, Kai Ren, Huayong Yang, Dong Han

引用次数: 0

What’s next toward the bio-design and manufacturing field? 生物设计和制造领域的下一步是什么?

1区医学

Bio-Design and Manufacturing Pub Date : 2023-10-26 DOI: 10.1007/s42242-023-00260-4

Liang Ma, Huayong Yang

引用次数: 0

Rapid printing of 3D porous scaffolds for breast reconstruction 乳房重建用3D多孔支架的快速打印

1区医学

Bio-Design and Manufacturing Pub Date : 2023-10-14 DOI: 10.1007/s42242-023-00253-3

Pengcheng Zhao, Biling Wang, Lu Wang, Zexin Fu, Jun Hu, Yande Liu, Ji Wang, Yong He

引用次数: 0

Highly specific characterization and discrimination of monosodium urate crystals in gouty arthritis based on aggregation-induced emission luminogens 基于聚集诱导发射发光素的痛风性关节炎尿酸钠晶体的高度特异性表征和鉴别

1区医学

Bio-Design and Manufacturing Pub Date : 2023-10-13 DOI: 10.1007/s42242-023-00252-4

Wenjuan Wang, Guiquan Zhang, Ziyi Chen, Hanlin Xu, Bohan Zhang, Rong Hu, Anjun Qin, Yinghui Hua

引用次数: 0

Design and realization of lung organoid cultures for COVID-19 applications 新型冠状病毒肺炎肺类器官培养的设计与实现

1区医学

Bio-Design and Manufacturing Pub Date : 2023-10-03 DOI: 10.1007/s42242-023-00255-1

Bing Ren, Tryanni R. Chiaravalloti, Nadine L. Belony, Diana I. Romero, Wenxuan Chai, Christopher Leon, Lizi Wu, Nazarius S. Lamango, Ite A. Offringa, Yong Huang

引用次数: 0

Fusobacterium nucleatum FabG 3-ketoacyl-acyl carrier protein reductase: purification, crystallization, and X-ray crystallographic analysis 核梭杆菌FabG 3-酮酰基酰基载体蛋白还原酶:纯化、结晶和x射线晶体学分析

1区医学

Bio-Design and Manufacturing Pub Date : 2023-09-30 DOI: 10.34184/kssb.2023.11.3.50

Shanru He, Yongbin Xu

引用次数: 0

Candida auris Aldo-keto reductase AldO: purification, crystallization, and X-ray crystallographic analysis 耳念珠菌醛酮还原酶:纯化、结晶和x射线晶体学分析

1区医学

Bio-Design and Manufacturing Pub Date : 2023-09-30 DOI: 10.34184/kssb.2023.11.3.45

Jie Zhang, Xue Bai, Shanru He, Yongbin Xu

引用次数: 0