Dr. Mahmoud A. El-Emam, Prof. Ling Zhou, Eman Yasser
{"title":"Numerical Investigation of Cyclone Separators: Physical Mechanisms and Theoretical Algorithms","authors":"Dr. Mahmoud A. El-Emam, Prof. Ling Zhou, Eman Yasser","doi":"10.1002/cben.202300052","DOIUrl":"10.1002/cben.202300052","url":null,"abstract":"<p>Gas-particle aero-type cyclones have revolutionized biochemical processes, engineering industries, and environmental pollution protection by effectively separating particles from gas. These devices rely on gravitational energy and centrifugal force to dissipate particle phase energy, but achieving optimal energy efficiency while minimizing pressure drop remains challenging. This has led to the development of various cyclone designs in commercial industries, each with unique energy efficiency characteristics. The intricate gas-particle flow inside cyclones is a critical issue impacted by cyclone geometry, operating conditions, and media parameters. Advanced numerical simulations have been employed to understand this complex flow pattern better, offering researchers valuable insights into the mechanisms of different cyclone separators. This comprehensive review explores the available numerical methods in the literature on cyclones and their corresponding validations. Computational numerical modeling is a promising technique for predicting cyclone energy efficiency, gas-particle behavior, and overall performance. This investigation delves into the progress and numerical forms of gas-particle flow cyclones, examining how different parameters impact cyclone performance and flow patterns within the two-phase flow. The future developments and challenges that may further promote the development of aero-type cyclone separators, providing theory and engineering support for future cyclone designs, are also covered. As a result, it can confidently be reported that aero-type cyclone separators remain a critical component in various industrial sectors, offering energy-efficient solutions for mitigating environmental pollutants and gas-particle separation systems. With continued development and research, these devices will undoubtedly shape the future of energy processes and engineering industries, ushering in a new era of sustainability and efficiency.</p>","PeriodicalId":48623,"journal":{"name":"ChemBioEng Reviews","volume":"11 2","pages":"299-338"},"PeriodicalIF":4.8,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139484003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dr. Bahar Aslanbay Guler, Ugur Tepe, Dr. Esra Imamoglu
{"title":"Sustainable Point of View: Life Cycle Analysis for Green Extraction Technologies","authors":"Dr. Bahar Aslanbay Guler, Ugur Tepe, Dr. Esra Imamoglu","doi":"10.1002/cben.202300056","DOIUrl":"10.1002/cben.202300056","url":null,"abstract":"<p>Microalgae have emerged as a promising source of renewable energy and natural bioproducts since they show high biomass productivity, offer carbon dioxide fixation, and exhibit a rich content of compounds. Recent efforts have focused on green extraction technologies that utilize green solvents to further promote sustainability and minimize the environmental impact of the microalgal process. At this point, life cycle analysis (LCA) provides valuable insights into the environmental impacts of specific products and techniques. A comprehensive overview of the life cycle environmental and energy assessments conducted for the extraction of metabolites from microalgae is presented. Special attention is given to using green extraction technologies, i.e., supercritical fluid extraction, pressurized liquid extraction, microwave-assisted extraction, ultrasound-assisted extraction, and pulsed-electric field extraction, and solvents to ensure sustainability. Additionally, the main principles, historical development, tools, and challenges of LCA are discussed. By addressing these aspects, the paper attracts attention to the environmental impacts associated with green extraction techniques for obtaining microalgal metabolites.</p>","PeriodicalId":48623,"journal":{"name":"ChemBioEng Reviews","volume":"11 2","pages":"348-362"},"PeriodicalIF":4.8,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cben.202300056","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139411543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Haruna Abdulbakee Muhammed, Dr. Mohammad Shahadat, Saleh Ali Tweib, Dr. Shehu Sa'ad Abdullahi, Dr. Mohammad Amir Qureshi, Dr. Yahaya Abdulrazaq, Dr. Abdullahi Haruna Birniwa, Dr. Ajaz Ahmad Wani, Dr. Ahmad Hussaini Jagaba, Dr. Rania Edrees Adam Mohammad, Dr. Mohd R. Razali, Dr. Saleh O. Alaswad
{"title":"Harvesting of Atmospheric Water Using Polymer-Based Hybrid Hydrogels","authors":"Haruna Abdulbakee Muhammed, Dr. Mohammad Shahadat, Saleh Ali Tweib, Dr. Shehu Sa'ad Abdullahi, Dr. Mohammad Amir Qureshi, Dr. Yahaya Abdulrazaq, Dr. Abdullahi Haruna Birniwa, Dr. Ajaz Ahmad Wani, Dr. Ahmad Hussaini Jagaba, Dr. Rania Edrees Adam Mohammad, Dr. Mohd R. Razali, Dr. Saleh O. Alaswad","doi":"10.1002/cben.202300032","DOIUrl":"10.1002/cben.202300032","url":null,"abstract":"<p>Atmospheric water harvesting (AWH) is an important parallel or supplemental freshwater production technique to liquid water resource-based technologies due to the availability of moisture resources regardless of location and the possibility of realizing decentralized applications. Recent developments to regulate the characteristic features and nanostructures of moisture-harvesting materials demonstrate new opportunities to improve device efficiency. Focusing on the design of water harvesting materials and the optimization of the overall system, this review sums up the most recent developments in this area and presents prospects for the future development of AWH. An overview of the processes involved in water sorption by various sorbents and the characteristics and functionality of the polyaniline-based hydrogels developed for AWH is given. Newly reported hydrogel sorbents used for AWH are evaluated, focusing on their benefits, drawbacks, and design methodologies. Several AWH-specific water harvesters are described and the impact of the system's mass and heat transfer on its operational effectiveness is explored. Finally, potential roadmaps for the development of this technology are detailed and the challenges in this subject from both a basic research and practical application perspective are discussed.</p>","PeriodicalId":48623,"journal":{"name":"ChemBioEng Reviews","volume":"11 2","pages":"197-214"},"PeriodicalIF":4.8,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139057025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enzymatic Catalysts for Hydroxamic Acid Formation: A Mini-Review","authors":"Dr. Rahul Vikram Singh","doi":"10.1002/cben.202300059","DOIUrl":"10.1002/cben.202300059","url":null,"abstract":"<p>In recent years, biocatalysts have emerged as crucial tool in organic synthesis, particularly for the production of drug intermediates and precursors, e.g., the synthesis of hydroxamic acids. Traditionally, hydroxamic acids were synthesized using organic chemistry methods. However, with the growing emphasis on sustainable and environment-friendly practices, the chemical industry has increasingly turned towards green synthesis approaches. The significance of hydroxamic acids in medicinal chemistry has also contributed to the changing trends. Following the approval of certain hydroxamic acids as histone deacetylase (HDAC) inhibitors for cancer treatment by the Food and Drug Administration (US-FDA), there has been a renewed focus on their synthesis and the development of derivatives with improved properties. As an alternative route, amidases have emerged as promising biocatalysts for hydroxamic acid synthesis through their acyltransferase activity. Recent advancements in the synthesis approaches for hydroxamic acids are reviewed. The biocatalytic routes are explored, emphasizing the use of amidases and their acyltransferase activity. The scope and potential applications of this chemoenzymatic approach in synthesizing various hydroxamic acids and their derivatives are discussed. Such advancements have the potential to revolutionize the production of these important compounds, making the synthesis process more sustainable, efficient, and economically viable.</p>","PeriodicalId":48623,"journal":{"name":"ChemBioEng Reviews","volume":"11 2","pages":"339-347"},"PeriodicalIF":4.8,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138826510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Najihah Mohd Noor, Ts. Dr. Amal A. M. Elgharbawy, Assoc. Prof. Dr. Muhammad Moniruzzaman, Prof. Masahiro Goto
{"title":"Unlocking the Anticancer Potential of Ionic Liquids","authors":"Najihah Mohd Noor, Ts. Dr. Amal A. M. Elgharbawy, Assoc. Prof. Dr. Muhammad Moniruzzaman, Prof. Masahiro Goto","doi":"10.1002/cben.202300051","DOIUrl":"10.1002/cben.202300051","url":null,"abstract":"<p>Despite advances in cancer treatment, many types of cancer still have high mortality rates, and the existing therapies can cause considerable side effects. Therefore, discovering new therapies, especially ones with fewer side effects, is desirable to improve the outcomes for cancer patients. Ionic liquids (ILs) have emerged as potential candidates for cancer treatment because of their particular physicochemical properties, which can be tailored for specific applications. In recent years, interest in exploring the potential of ILs in cancer treatment has been growing, and several studies have demonstrated the effectiveness of ILs in inhibiting cancer-cell growth. This review provides insight into the anticancer potential of ILs, exploring the diverse applications and the underlying mechanisms behind the cytotoxicity toward cancer cells of ILs. Understanding the mechanisms behind the cytotoxicity of ILs can aid in the design and optimization of IL-based cancer therapies. By focusing on specific pathways and targets, IL-based cancer therapies may be developed that offer new possibilities for treating this devastating disease.</p>","PeriodicalId":48623,"journal":{"name":"ChemBioEng Reviews","volume":"11 2","pages":"231-252"},"PeriodicalIF":4.8,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138631339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Hemavathi, Dr. Srinivas Srirama, Dr. A. S. Prakash
{"title":"Present and Future Generation of Secondary Batteries: A Review","authors":"S. Hemavathi, Dr. Srinivas Srirama, Dr. A. S. Prakash","doi":"10.1002/cben.202200040","DOIUrl":"10.1002/cben.202200040","url":null,"abstract":"<p>Major support for the future energy storage and application will benefit from lithium-ion batteries (LIBs) with high energy density and high power. LIBs are currently the most common battery type for most applications, but soon a broader range of battery types and higher energy densities will be available. In the near future, hundreds of millions of electric vehicles are expected to be on the road, and a large amount of cobalt will be depleted. Various kinds of batteries are developed today to store energy, including Li-ion, lead-acid, Ni-MH, redox flow, Na-ion, Mg-ion, Li-air, Al-ion, Li/S, NC-based batteries, Al-based batteries, metal-air batteries, solid-state batteries, etc. There are several types of battery components, such as electrodes, electrolytes, separators, etc. Cell chemistry and component diversity will continue to increase with future generations of batteries. Next-generation LIBs and sodium-ion batteries are explored for their ability to reduce active ion loss and increase energy density by pre-lithiation. To maximize the electrochemical system's performance, various scientific and technological approaches are needed to maximize the potential of battery chemistry.</p>","PeriodicalId":48623,"journal":{"name":"ChemBioEng Reviews","volume":"10 6","pages":"1123-1145"},"PeriodicalIF":4.8,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138533572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abir Lal Bose, Debapriya Bhattacharjee, Dr. Debajyoti Goswami
{"title":"Process Parameters Influence Product Yield and Kinetic Parameters in Lipase Catalysis","authors":"Abir Lal Bose, Debapriya Bhattacharjee, Dr. Debajyoti Goswami","doi":"10.1002/cben.202300035","DOIUrl":"10.1002/cben.202300035","url":null,"abstract":"<p>Effects of process parameters like enzyme concentration, concentration and type of substrate, pH, temperature, speed of agitation, and pressure on lipase catalysis are reviewed. The enzyme concentration controls its interfacial presence and consequently the rate of reaction. A change in substrate concentration alters lipase kinetics. Substrate-lipase interaction varies with substrate type and pH. Water concentration and agitation affect the extent of interfacial area. Temperature impacts the rate and thermal denaturation of enzymes. Statistical optimization can solve the problem of controlling a variable's effect by other variables. Immobilization support and nonionic surfactant altered the significance of enzyme concentration. The lipase type controlled the impact of concentrations of enzyme, substrate, and water. The water content was important during lipase-catalyzed hydrolysis and esterification. The mode of agitation influenced the significance of enzyme concentration and temperature. Time had a remarkable impact during hydrolysis. Temperature, substrate type, and chain length notably controlled kinetic parameters. This work paves the way for similar studies on other enzymes.</p>","PeriodicalId":48623,"journal":{"name":"ChemBioEng Reviews","volume":"11 2","pages":"178-196"},"PeriodicalIF":4.8,"publicationDate":"2023-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138533571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}