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Air Quality and Health Impacts of Onshore Oil and Gas Flaring and Venting Activities Estimated Using Refined Satellite-Based Emissions 利用基于卫星的精细排放估算陆上油气燃烧和排放活动对空气质量和健康的影响
IF 4.8 2区 医学
Geohealth Pub Date : 2024-03-06 DOI: 10.1029/2023GH000938
Huy Tran, Erin Polka, Jonathan J. Buonocore, Ananya Roy, Beth Trask, Hillary Hull, Saravanan Arunachalam
{"title":"Air Quality and Health Impacts of Onshore Oil and Gas Flaring and Venting Activities Estimated Using Refined Satellite-Based Emissions","authors":"Huy Tran,&nbsp;Erin Polka,&nbsp;Jonathan J. Buonocore,&nbsp;Ananya Roy,&nbsp;Beth Trask,&nbsp;Hillary Hull,&nbsp;Saravanan Arunachalam","doi":"10.1029/2023GH000938","DOIUrl":"https://doi.org/10.1029/2023GH000938","url":null,"abstract":"<p>Emissions from flaring and venting (FV) in oil and gas (O&amp;G) production are difficult to quantify due to their intermittent activities and lack of adequate monitoring and reporting. Given their potentially significant contribution to total emissions from the O&amp;G sector in the United States, we estimate emissions from FV using Visible Infrared Imaging Radiometer Suite satellite observations and state/local reported data on flared gas volume. These refined estimates are higher than those reported in the National Emission Inventory: by up to 15 times for fine particulate matter (PM<sub>2.5</sub>), two times for sulfur dioxides, and 22% higher for nitrogen oxides (NO<sub>x</sub>). Annual average contributions of FV to ozone (O<sub>3</sub>), NO<sub>2</sub>, and PM<sub>2.5</sub> in the conterminous U.S. (CONUS) are less than 0.15%, but significant contributions of up to 60% are found in O&amp;G fields with FV. FV contributions are higher in winter than in summer months for O<sub>3</sub> and PM<sub>2.5</sub>; an inverse behavior is found for NO<sub>2</sub>. Nitrate aerosol contributions to PM<sub>2.5</sub> are highest in the Denver basin whereas in the Permian and Bakken basins, sulfate and elemental carbon aerosols are the major contributors. Over four simulated months in 2016 for the entire CONUS, FV contributes 210 additional instances of exceedances to the daily maximum 8-hr average O<sub>3</sub> and has negligible contributions to exceedance of NO<sub>2</sub> and PM<sub>2.5</sub>, given the current form of the national ambient air quality standards. FV emissions are found to cause over $7.4 billion in health damages, 710 premature deaths, and 73,000 asthma exacerbations among children annually.</p>","PeriodicalId":48618,"journal":{"name":"Geohealth","volume":"8 3","pages":""},"PeriodicalIF":4.8,"publicationDate":"2024-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1029/2023GH000938","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140043191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impacts of Deforestation on Childhood Malaria Depend on Wealth and Vector Biology 森林砍伐对儿童疟疾的影响取决于财富和病媒生物学
IF 4.8 2区 医学
Geohealth Pub Date : 2024-02-28 DOI: 10.1029/2022GH000764
Tafesse Kefyalew Estifanos, Brendan Fisher, Gillian L. Galford, Taylor H. Ricketts
{"title":"Impacts of Deforestation on Childhood Malaria Depend on Wealth and Vector Biology","authors":"Tafesse Kefyalew Estifanos,&nbsp;Brendan Fisher,&nbsp;Gillian L. Galford,&nbsp;Taylor H. Ricketts","doi":"10.1029/2022GH000764","DOIUrl":"https://doi.org/10.1029/2022GH000764","url":null,"abstract":"<p>Ecosystem change can profoundly affect human well-being and health, including through changes in exposure to vector-borne diseases. Deforestation has increased human exposure to mosquito vectors and malaria risk in Africa, but there is little understanding of how socioeconomic and ecological factors influence the relationship between deforestation and malaria risk. We examined these interrelationships in six sub-Saharan African countries using demographic and health survey data linked to remotely sensed environmental variables for 11,746 children under 5 years old. We found that the relationship between deforestation and malaria prevalence varies by wealth levels. Deforestation is associated with increased malaria prevalence in the poorest households, but there was not significantly increased malaria prevalence in the richest households, suggesting that deforestation has disproportionate negative health impacts on the poor. In poorer households, malaria prevalence was 27%–33% larger for one standard deviation increase in deforestation across urban and rural populations. Deforestation is also associated with increased malaria prevalence in regions where <i>Anopheles gambiae</i> and <i>Anopheles funestus</i> are dominant vectors, but not in areas of <i>Anopheles arabiensis</i>. These findings indicate that deforestation is an important driver of malaria risk among the world's most vulnerable children, and its impact depends critically on often-overlooked social and biological factors. An in-depth understanding of the links between ecosystems and human health is crucial in designing conservation policies that benefit people and the environment.</p>","PeriodicalId":48618,"journal":{"name":"Geohealth","volume":"8 3","pages":""},"PeriodicalIF":4.8,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1029/2022GH000764","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139993878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tracking Progress Toward Urban Nature Targets Using Landcover and Vegetation Indices: A Global Study for the 96 C40 Cities 利用土地覆盖物和植被指数跟踪城市自然目标的进展情况:针对 96 个 C40 城市的全球研究
IF 4.8 2区 医学
Geohealth Pub Date : 2024-02-26 DOI: 10.1029/2023GH000996
Greta K. Martin, Katelyn O’Dell, Patrick L. Kinney, Marcia Pescador-Jimenez, David Rojas-Rueda, Robert Canales, Susan C. Anenberg
{"title":"Tracking Progress Toward Urban Nature Targets Using Landcover and Vegetation Indices: A Global Study for the 96 C40 Cities","authors":"Greta K. Martin,&nbsp;Katelyn O’Dell,&nbsp;Patrick L. Kinney,&nbsp;Marcia Pescador-Jimenez,&nbsp;David Rojas-Rueda,&nbsp;Robert Canales,&nbsp;Susan C. Anenberg","doi":"10.1029/2023GH000996","DOIUrl":"https://doi.org/10.1029/2023GH000996","url":null,"abstract":"<p>Access to urban natural space, including blue and greenspace, is associated with improved health. In 2021, the C40 Cities Climate Leadership Group set 2030 Urban Nature Declaration (UND) targets: “Quality Total Cover” (30% green area within each city) and “Equitable Spatial Distribution” (70% of the population living close to natural space). We evaluate progress toward these targets in the 96 C40 cities using globally available, high-resolution data sets for landcover and normalized difference vegetation index (NDVI). We use the European Space Agency (ESA)'s WorldCover data set to define greenspace with discrete landcover categories and ESA's Sentinel-2A to calculate NDVI, adding the “open water” landcover category to characterize total natural space. We compare 2020 levels of urban green and natural space to the two UND targets and predict the city-specific NDVI level consistent with the UND targets using linear regressions. The 96-city mean NDVI was 0.538 (range: 0.148, 0.739). Most (80%) cities meet the Quality Total Cover target, and nearly half (47%) meet the Equitable Spatial Distribution target. Landcover-measured greenspace and total natural space were strong (mean <i>R</i><sup>2</sup> = 0.826) and moderate (mean <i>R</i><sup>2</sup> = 0.597) predictors of NDVI and our NDVI-based natural space proximity measure, respectively. The 96-city mean predicted NDVI value of meeting the UND targets was 0.478 (range: 0.352–0.565) for Quality Total Cover and 0.660 (range: 0.498–0.767) for Equitable Spatial Distribution. Our translation of the area- and access-based metrics common in urban natural space targets into the NDVI metric used in epidemiology allows for quantifying the health benefits of achieving such targets.</p>","PeriodicalId":48618,"journal":{"name":"Geohealth","volume":"8 3","pages":""},"PeriodicalIF":4.8,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1029/2023GH000996","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139976529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Satellite Remote Sensing: A Tool to Support Harmful Algal Bloom Monitoring and Recreational Health Advisories in a California Reservoir 卫星遥感:支持加利福尼亚州水库有害藻华监测和娱乐健康警告的工具
IF 4.8 2区 医学
Geohealth Pub Date : 2024-02-23 DOI: 10.1029/2023GH000941
Brittany N. Lopez Barreto, Erin L. Hestir, Christine M. Lee, Marc W. Beutel
{"title":"Satellite Remote Sensing: A Tool to Support Harmful Algal Bloom Monitoring and Recreational Health Advisories in a California Reservoir","authors":"Brittany N. Lopez Barreto,&nbsp;Erin L. Hestir,&nbsp;Christine M. Lee,&nbsp;Marc W. Beutel","doi":"10.1029/2023GH000941","DOIUrl":"https://doi.org/10.1029/2023GH000941","url":null,"abstract":"<p>Cyanobacterial harmful algal blooms (cyanoHABs) can harm people, animals, and affect consumptive and recreational use of inland waters. Monitoring cyanoHABs is often limited. However, chlorophyll-<i>a</i> (chl-<i>a</i>) is a common water quality metric and has been shown to have a relationship with cyanobacteria. The World Health Organization (WHO) recently updated their previous 1999 cyanoHAB guidance values (GVs) to be more practical by basing the GVs on chl-<i>a</i> concentration rather than cyanobacterial counts. This creates an opportunity for widespread cyanoHAB monitoring based on chl-<i>a</i> proxies, with satellite remote sensing (SRS) being a potentially powerful tool. We used Sentinel-2 (S2) and Sentinel-3 (S3) to map chl-<i>a</i> and cyanobacteria, respectively, classified chl-<i>a</i> values according to WHO GVs, and then compared them to cyanotoxin advisories issued by the California Department of Water Resources (DWR) at San Luis Reservoir, key infrastructure in California's water system. We found reasonably high rates of total agreement between advisories by DWR and SRS, however rates of agreement varied for S2 based on algorithm. Total agreement was 83% for S3, and 52%–79% for S2. False positive and false negative rates for S3 were 12% and 23%, respectively. S2 had 12%–80% false positive rate and 0%–38% false negative rate, depending on algorithm. Using SRS-based chl-<i>a</i> GVs as an early indicator for possible exposure advisories and as a trigger for in situ sampling may be effective to improve public health warnings. Implementing SRS for cyanoHAB monitoring could fill temporal data gaps and provide greater spatial information not available from in situ measurements alone.</p>","PeriodicalId":48618,"journal":{"name":"Geohealth","volume":"8 2","pages":""},"PeriodicalIF":4.8,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1029/2023GH000941","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139937310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Health-Damaging Climate Events Highlight the Need for Interdisciplinary, Engaged Research 损害健康的气候事件凸显跨学科参与研究的必要性
IF 4.8 2区 医学
Geohealth Pub Date : 2024-02-16 DOI: 10.1029/2024GH001022
Jennifer D. Stowell, Susan Anenberg, Benjamin F. Zaitchik, Daniel Q. Tong, Claire J. Horwell, Dennis P. Stolle, Rita R. Colwell, Christine McEntee
{"title":"Health-Damaging Climate Events Highlight the Need for Interdisciplinary, Engaged Research","authors":"Jennifer D. Stowell,&nbsp;Susan Anenberg,&nbsp;Benjamin F. Zaitchik,&nbsp;Daniel Q. Tong,&nbsp;Claire J. Horwell,&nbsp;Dennis P. Stolle,&nbsp;Rita R. Colwell,&nbsp;Christine McEntee","doi":"10.1029/2024GH001022","DOIUrl":"https://doi.org/10.1029/2024GH001022","url":null,"abstract":"<p>In 2023 human populations experienced multiple record-breaking climate events, with widespread impacts on human health and well-being. These events include extreme heat domes, drought, severe storms, flooding, and wildfires. Due to inherent lags in the climate system, we can expect such extremes to continue for multiple decades after reaching net zero carbon emissions. Unfortunately, despite these significant current and future impacts, funding for research in climate and health has lagged behind that for other geoscience and biomedical research. While some initial efforts from funding agencies are evident, there is still a significant need to increase the resources available for multidisciplinary research in the face of this issue. As a group of experts at this important intersection, we call for a more concerted effort to encourage interdisciplinary and policy-relevant investigations into the detrimental health effects of continued climate change.</p>","PeriodicalId":48618,"journal":{"name":"Geohealth","volume":"8 2","pages":""},"PeriodicalIF":4.8,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1029/2024GH001022","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139745052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reflections on a Century of Extreme Heat Event-Related Mortality Reporting in Canada 对加拿大一个世纪以来极端高温事件相关死亡率报告的反思
IF 4.8 2区 医学
Geohealth Pub Date : 2024-02-16 DOI: 10.1029/2023GH000895
Liv Yoon, Gregory R. A. Richardson, Melissa Gorman
{"title":"Reflections on a Century of Extreme Heat Event-Related Mortality Reporting in Canada","authors":"Liv Yoon,&nbsp;Gregory R. A. Richardson,&nbsp;Melissa Gorman","doi":"10.1029/2023GH000895","DOIUrl":"https://doi.org/10.1029/2023GH000895","url":null,"abstract":"<p>Climate change is causing more frequent and severe extreme heat events (EHEs) in Canada, resulting in significant loss of life. However, patterns across mortality reporting for historical EHEs have not been analyzed. To address this gap, we studied deaths in Canadian EHEs from 1936 to 2021, identifying trends and challenges. Our analysis revealed inconsistencies in mortality data, discrepancies between vulnerable populations identified, difficulties in determining the cause of death, and inconsistent reporting on social vulnerability indicators. We provide some observations that could help inform solutions to address the gaps and challenges, by moving toward more consistent and comprehensive reporting to ensure no population is overlooked. Accurately accounting for affected populations could help better target evidence-based interventions, and reduce vulnerability to extreme heat.</p>","PeriodicalId":48618,"journal":{"name":"Geohealth","volume":"8 2","pages":""},"PeriodicalIF":4.8,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1029/2023GH000895","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139745053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identification of Neighborhood Hotspots via the Cumulative Hazard Index: Results From a Community-Partnered Low-Cost Sensor Deployment 通过累积危害指数识别邻里热点:社区合作的低成本传感器部署成果
IF 4.8 2区 医学
Geohealth Pub Date : 2024-02-14 DOI: 10.1029/2023GH000935
Sakshi Jain, Rivkah Gardner-Frolick, Nika Martinussen, Dan Jackson, Amanda Giang, Naomi Zimmerman
{"title":"Identification of Neighborhood Hotspots via the Cumulative Hazard Index: Results From a Community-Partnered Low-Cost Sensor Deployment","authors":"Sakshi Jain,&nbsp;Rivkah Gardner-Frolick,&nbsp;Nika Martinussen,&nbsp;Dan Jackson,&nbsp;Amanda Giang,&nbsp;Naomi Zimmerman","doi":"10.1029/2023GH000935","DOIUrl":"https://doi.org/10.1029/2023GH000935","url":null,"abstract":"<p>The Strathcona neighborhood in Vancouver is particularly vulnerable to environmental injustice due to its close proximity to the Port of Vancouver, and a high proportion of Indigenous and low-income households. Furthermore, local sources of air pollutants (e.g., roadways) can contribute to small-scale variations within communities. The aim of this study was to assess hyperlocal air quality patterns (intra-neighborhood variability) and compare them to average Vancouver concentrations (inter-neighborhood variability) to identify possible disparities in air pollution exposure for the Strathcona community. Between April and August 2022, 11 low-cost sensors (LCS) were deployed within the neighborhood to measure PM<sub>2.5</sub>, NO<sub>2</sub>, and O<sub>3</sub> concentrations. The collected 15-min concentrations were down-averaged to daily concentrations and compared to greater Vancouver region concentrations to quantify the exposures faced by the community relative to the rest of the region. Concentrations were also estimated at every 25 m grid within the neighborhood to quantify the distribution of air pollution within the community. Using population information from census data, cumulative hazard indices (CHIs) were computed for every dissemination block. We found that although PM<sub>2.5</sub> concentrations in the neighborhood were lower than regional Vancouver averages, daily NO<sub>2</sub> concentrations and summer O<sub>3</sub> concentrations were consistently higher. Additionally, although CHIs varied daily, we found that CHIs were consistently higher in areas with high commercial activity. As such, estimating CHI for dissemination blocks was useful in identifying hotspots and potential areas of concern within the neighborhood. This information can collectively assist the community in their advocacy efforts.</p>","PeriodicalId":48618,"journal":{"name":"Geohealth","volume":"8 2","pages":""},"PeriodicalIF":4.8,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1029/2023GH000935","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139739249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PM2.5 Is Insufficient to Explain Personal PAH Exposure PM2.5 不足以解释个人 PAH 暴露
IF 4.8 2区 医学
Geohealth Pub Date : 2024-02-10 DOI: 10.1029/2023GH000937
Lisa M. Bramer, Holly M. Dixon, Diana Rohlman, Richard P. Scott, Rachel L. Miller, Laurel Kincl, Julie B. Herbstman, Katrina M. Waters, Kim A. Anderson
{"title":"PM2.5 Is Insufficient to Explain Personal PAH Exposure","authors":"Lisa M. Bramer,&nbsp;Holly M. Dixon,&nbsp;Diana Rohlman,&nbsp;Richard P. Scott,&nbsp;Rachel L. Miller,&nbsp;Laurel Kincl,&nbsp;Julie B. Herbstman,&nbsp;Katrina M. Waters,&nbsp;Kim A. Anderson","doi":"10.1029/2023GH000937","DOIUrl":"https://doi.org/10.1029/2023GH000937","url":null,"abstract":"<p>To understand how chemical exposure can impact health, researchers need tools that capture the complexities of personal chemical exposure. In practice, fine particulate matter (PM<sub>2.5</sub>) air quality index (AQI) data from outdoor stationary monitors and Hazard Mapping System (HMS) smoke density data from satellites are often used as proxies for personal chemical exposure, but do not capture total chemical exposure. Silicone wristbands can quantify more individualized exposure data than stationary air monitors or smoke satellites. However, it is not understood how these proxy measurements compare to chemical data measured from wristbands. In this study, participants wore daily wristbands, carried a phone that recorded locations, and answered daily questionnaires for a 7-day period in multiple seasons. We gathered publicly available daily PM<sub>2.5</sub> AQI data and HMS data. We analyzed wristbands for 94 organic chemicals, including 53 polycyclic aromatic hydrocarbons. Wristband chemical detections and concentrations, behavioral variables (e.g., time spent indoors), and environmental conditions (e.g., PM<sub>2.5</sub> AQI) significantly differed between seasons. Machine learning models were fit to predict personal chemical exposure using PM<sub>2.5</sub> AQI only, HMS only, and a multivariate feature set including PM<sub>2.5</sub> AQI, HMS, and other environmental and behavioral information. On average, the multivariate models increased predictive accuracy by approximately 70% compared to either the AQI model or the HMS model for all chemicals modeled. This study provides evidence that PM<sub>2.5</sub> AQI data alone or HMS data alone is insufficient to explain personal chemical exposures. Our results identify additional key predictors of personal chemical exposure.</p>","PeriodicalId":48618,"journal":{"name":"Geohealth","volume":"8 2","pages":""},"PeriodicalIF":4.8,"publicationDate":"2024-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1029/2023GH000937","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139720151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spatio-Temporal Pattern of Tuberculosis Distribution in Romania and Particulate Matter Pollution Associated With Risk of Infection 罗马尼亚结核病分布的时空模式以及与感染风险相关的颗粒物污染
IF 4.8 2区 医学
Geohealth Pub Date : 2024-02-06 DOI: 10.1029/2023GH000972
D. Peptenatu, A. M. Băloi, O. Andronic, A. Bolocan, N. Cioran, A. K. Gruia, A. Grecu, T. C. Panciu, L. Georgescu, I. Munteanu, A. Pistol, F. Furtunescu, I. R. Strâmbu, E. Ibrahim, D. Băiceanu, G. G. Popescu, D. Păduraru, V. Jinga, B. Mahler
{"title":"Spatio-Temporal Pattern of Tuberculosis Distribution in Romania and Particulate Matter Pollution Associated With Risk of Infection","authors":"D. Peptenatu,&nbsp;A. M. Băloi,&nbsp;O. Andronic,&nbsp;A. Bolocan,&nbsp;N. Cioran,&nbsp;A. K. Gruia,&nbsp;A. Grecu,&nbsp;T. C. Panciu,&nbsp;L. Georgescu,&nbsp;I. Munteanu,&nbsp;A. Pistol,&nbsp;F. Furtunescu,&nbsp;I. R. Strâmbu,&nbsp;E. Ibrahim,&nbsp;D. Băiceanu,&nbsp;G. G. Popescu,&nbsp;D. Păduraru,&nbsp;V. Jinga,&nbsp;B. Mahler","doi":"10.1029/2023GH000972","DOIUrl":"https://doi.org/10.1029/2023GH000972","url":null,"abstract":"<p>The study proposes a dynamic spatio-temporal profile of the distribution of tuberculosis incidence and air pollution in Romania, where this infectious disease induces more than 8,000 new cases annually. The descriptive analysis for the years 2012–2021 assumes an identification of the structuring patterns of mycobacterium tuberculosis risk in the Romanian population, according to gender and age, exploiting spatial modeling techniques of time series data. Through spatial autocorrelation, the degree of similarity between the analyzed territorial systems was highlighted and the relationships that are built between the analysis units in spatial proximity were investigated. By modeling the geographical distribution of tuberculosis, the spatial correlation with particulate matter (PM<sub>2.5</sub>) pollution was revealed. The identification of clusters of infected persons is an indispensable step in the construction of efficient tuberculosis management systems. The results highlight the link between the distribution of tuberculosis, air pollution and socio-economic development, which requires a detailed analysis of the epidemiological data obtained in the national tuberculosis surveillance and control program from the perspective of geographical distribution.</p>","PeriodicalId":48618,"journal":{"name":"Geohealth","volume":"8 2","pages":""},"PeriodicalIF":4.8,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1029/2023GH000972","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139695318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial Space Weathering to Mimic Solar Wind Enhances the Toxicity of Lunar Dust Simulants in Human Lung Cells 模拟太阳风的人工太空风化增强了月球尘埃模拟物在人类肺细胞中的毒性
IF 4.8 2区 医学
Geohealth Pub Date : 2024-02-01 DOI: 10.1029/2023GH000840
J. H. M. Chang, Z. Xue, J. Bauer, B. Wehle, D. A. Hendrix, T. Catalano, J. A. Hurowitz, H. Nekvasil, B. Demple
{"title":"Artificial Space Weathering to Mimic Solar Wind Enhances the Toxicity of Lunar Dust Simulants in Human Lung Cells","authors":"J. H. M. Chang,&nbsp;Z. Xue,&nbsp;J. Bauer,&nbsp;B. Wehle,&nbsp;D. A. Hendrix,&nbsp;T. Catalano,&nbsp;J. A. Hurowitz,&nbsp;H. Nekvasil,&nbsp;B. Demple","doi":"10.1029/2023GH000840","DOIUrl":"10.1029/2023GH000840","url":null,"abstract":"<p>During NASA's Apollo missions, inhalation of dust particles from lunar regolith was identified as a potential occupational hazard for astronauts. These fine particles adhered tightly to spacesuits and were unavoidably brought into the living areas of the spacecraft. Apollo astronauts reported that exposure to the dust caused intense respiratory and ocular irritation. This problem is a potential challenge for the Artemis Program, which aims to return humans to the Moon for extended stays in this decade. Since lunar dust is “weathered” by space radiation, solar wind, and the incessant bombardment of micrometeorites, we investigated whether treatment of lunar regolith simulants to mimic space weathering enhanced their toxicity. Two such simulants were employed in this research, Lunar Mare Simulant-1 (LMS-1), and Lunar Highlands Simulant-1 (LHS-1), which were added to cultures of human lung epithelial cells (A549) to simulate lung exposure to the dusts. In addition to pulverization, previously shown to increase dust toxicity sharply, the simulants were exposed to hydrogen gas at high temperature as a proxy for solar wind exposure. This treatment further increased the toxicity of both simulants, as measured by the disruption of mitochondrial function, and damage to DNA both in mitochondria and in the nucleus. By testing the effects of supplementing the cells with an antioxidant (N-acetylcysteine), we showed that a substantial component of this toxicity arises from free radicals. It remains to be determined to what extent the radicals arise from the dust itself, as opposed to their active generation by inflammatory processes in the treated cells.</p>","PeriodicalId":48618,"journal":{"name":"Geohealth","volume":"8 2","pages":""},"PeriodicalIF":4.8,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1029/2023GH000840","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139663626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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