Yale Journal of Biology and Medicine最新文献_第4页

Perspectives of Chronic Kidney Disease Patients on Readiness for Advance Care Planning at Komfo Anokye Teaching Hospital, Ghana. 加纳 Komfo Anokye 教学医院慢性肾病患者对预先护理规划准备情况的看法。

IF 2.5 3区工程技术

Yale Journal of Biology and Medicine Pub Date : 2024-06-28 eCollection Date: 2024-06-01 DOI: 10.59249/NZCS6192

Abigail S Boakye, Gladys Dzansi, Rasheed Ofosu-Poku, Michael O Ansah, Alfred K Owusu, Gladys Anyane, Juliana Addai, Alberta D Dzaka, Yakubu Salifu

{"title":"Perspectives of Chronic Kidney Disease Patients on Readiness for Advance Care Planning at Komfo Anokye Teaching Hospital, Ghana.","authors":"Abigail S Boakye, Gladys Dzansi, Rasheed Ofosu-Poku, Michael O Ansah, Alfred K Owusu, Gladys Anyane, Juliana Addai, Alberta D Dzaka, Yakubu Salifu","doi":"10.59249/NZCS6192","DOIUrl":"10.59249/NZCS6192","url":null,"abstract":"This study examined the impact of advance care planning (ACP) on the quality of life for patients with chronic kidney disease (CKD) at Komfo Anokye Teaching Hospital in Ghana. It specifically investigated patients' perspectives on their readiness for ACP. Utilizing a qualitative descriptive design, one-on-one interviews were conducted with CKD patients at the renal clinic, employing a semi-structured interview guide for thematic analysis of audio data. The findings revealed a gap in understanding among CKD patients, with participants acknowledging their vulnerability to renal failure, often linked to a medical history of diabetes and hypertension. Despite recognizing potential outcomes such as dialysis dependency or death, some patients retained hope for a cure, relying on faith. The initial kidney failure diagnosis induced shock and distress, leading many patients to prefer the comfort and familiarity of home-based care, including dialysis. Meanwhile, a minority favored hospital care to protect their children from psychological trauma. Most patients deemed legal preparations unnecessary, citing limited assets or a lack of concern for posthumous estate execution. These insights emphasize the necessity for targeted education and support in ACP to enhance patient outcomes in chronic kidney disease care and end-of-life planning.","PeriodicalId":48617,"journal":{"name":"Yale Journal of Biology and Medicine","volume":"97 2","pages":"115-124"},"PeriodicalIF":2.5,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11202105/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Natural Bioactive Compounds from Macroalgae and Microalgae for the Treatment of Alzheimer's Disease: A Review. 从大型藻类和微型藻类中提取天然生物活性化合物用于治疗阿尔茨海默氏症：综述。

IF 2.5 3区工程技术

Yale Journal of Biology and Medicine Pub Date : 2024-06-28 eCollection Date: 2024-06-01 DOI: 10.59249/JNKB9714

Jia Yee Lee, Chiew Yen Wong, Rhun Yian Koh, Chooi Ling Lim, Yih Yih Kok, Soi Moi Chye

{"title":"Natural Bioactive Compounds from Macroalgae and Microalgae for the Treatment of Alzheimer's Disease: A Review.","authors":"Jia Yee Lee, Chiew Yen Wong, Rhun Yian Koh, Chooi Ling Lim, Yih Yih Kok, Soi Moi Chye","doi":"10.59249/JNKB9714","DOIUrl":"10.59249/JNKB9714","url":null,"abstract":"Neuroinflammation, toxic protein aggregation, oxidative stress, and mitochondrial dysfunction are key pathways in neurodegenerative diseases like Alzheimer's disease (AD). Targeting these mechanisms with antioxidants, anti-inflammatory compounds, and inhibitors of Aβ formation and aggregation is crucial for treatment. Marine algae are rich sources of bioactive compounds, including carbohydrates, phenolics, fatty acids, phycobiliproteins, carotenoids, fatty acids, and vitamins. In recent years, they have attracted interest from the pharmaceutical and nutraceutical industries due to their exceptional biological activities, which include anti-inflammation, antioxidant, anticancer, and anti-apoptosis properties. Multiple lines of evidence have unveiled the potential neuroprotective effects of these multifunctional algal compounds for application in treating and managing AD. This article will provide insight into the molecular mechanisms underlying the neuroprotective effects of bioactive compounds derived from algae based on in vitro and in vivo models of neuroinflammation and AD. We will also discuss their potential as disease-modifying and symptomatic treatment strategies for AD.","PeriodicalId":48617,"journal":{"name":"Yale Journal of Biology and Medicine","volume":"97 2","pages":"205-224"},"PeriodicalIF":2.5,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11202106/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Therapeutic Potential of Nitrogen-Doped Rutin-Bound Glucose Carbon Dots for Alzheimer's Disease. 掺氮芦丁结合葡萄糖碳点对阿尔茨海默病的治疗潜力

IF 2.5 3区工程技术

Yale Journal of Biology and Medicine Pub Date : 2024-06-28 eCollection Date: 2024-06-01 DOI: 10.59249/EWOI2166

Sana Khan, Faria Hasan Jatala, Alveena Muti, Noor Afza, Aneeqa Noor, Sara Mumtaz, Saima Zafar

{"title":"Therapeutic Potential of Nitrogen-Doped Rutin-Bound Glucose Carbon Dots for Alzheimer's Disease.","authors":"Sana Khan, Faria Hasan Jatala, Alveena Muti, Noor Afza, Aneeqa Noor, Sara Mumtaz, Saima Zafar","doi":"10.59249/EWOI2166","DOIUrl":"10.59249/EWOI2166","url":null,"abstract":"The blood-brain barrier (BBB) prevents the use of many drugs for the treatment of neurological disorders. Recently, nitrogen-doped carbon dots (NCDs) have emerged as promising nanocarriers to cross BBB. The primary focus of our study was to evaluate the effectiveness of NCDs for the symptomatic treatment of Alzheimer's disease (AD). In this study, we developed and characterized NCDs bound to rutin, a flavonoid with known benefits for AD. Despite its benefits, the transportation of rutin via NCDs for AD therapy has not been explored previously. We characterized the particles using FTIR and UV-visible spectroscopy followed by atomic force microscopy. Once the design was optimized and validated, we performed in vivo testing via a hemolytic assay to optimize the dosage. Preliminary in vitro testing was performed in AlCl3-induced rat models of AD whereby a single dose of 10 mg/kg NCDs-rutin was administered intraperitoneally. Interestingly, this single dose of 10 mg/kg NCDs-rutin produced the same behavioral effects as 50 mg/kg rutin administered intraperitoneally for 1 month. Similarly, histological and biomarker profiles (SOD2 and TLR4) also presented significant protective effects of NCDs-rutin against neuronal loss, inflammation, and oxidative stress. Hence, NCDs-rutin are a promising approach for the treatment of neurological diseases.","PeriodicalId":48617,"journal":{"name":"Yale Journal of Biology and Medicine","volume":"97 2","pages":"153-164"},"PeriodicalIF":2.5,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11202111/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chronic Pain and Joint Hypermobility: A Brief Diagnostic Review for Clinicians and the Potential Application of Infrared Thermography in Screening Hypermobile Inflamed Joints. 慢性疼痛与关节过度活动：为临床医生提供的简明诊断综述以及红外热成像技术在筛查过度活动的发炎关节中的潜在应用》。

IF 2.5 3区工程技术

Yale Journal of Biology and Medicine Pub Date : 2024-06-28 eCollection Date: 2024-06-01 DOI: 10.59249/WGRS1619

João Alberto de Souza Ribeiro, Guilherme Gomes, Alexandre Aldred, Ivan Cesar Desuó, Luciana Aparecida Giacomini

{"title":"Chronic Pain and Joint Hypermobility: A Brief Diagnostic Review for Clinicians and the Potential Application of Infrared Thermography in Screening Hypermobile Inflamed Joints.","authors":"João Alberto de Souza Ribeiro, Guilherme Gomes, Alexandre Aldred, Ivan Cesar Desuó, Luciana Aparecida Giacomini","doi":"10.59249/WGRS1619","DOIUrl":"10.59249/WGRS1619","url":null,"abstract":"Joint hypermobility syndromes, particularly chronic pain associated with this condition, including Hypermobile Ehlers-Danlos Syndrome (hEDS) and Hypermobility Spectrum Disorders (HSD), present diagnostic challenges due to their multifactorial origins and remain poorly understood from biomechanical and genomic-molecular perspectives. Recent diagnostic guidelines have differentiated hEDS, HSD, and benign joint hypermobility, providing a more objective diagnostic framework. However, incorrect diagnoses and underdiagnoses persist, leading to prolonged journeys for affected individuals. Musculoskeletal manifestations, chronic pain, dysautonomia, and gastrointestinal symptoms illustrate the multifactorial impact of these conditions, affecting both the physical and emotional well-being of affected individuals. Infrared thermography (IRT) emerges as a promising tool for joint assessment, especially in detecting inflammatory processes. Thermal distribution patterns offer valuable insights into joint dysfunctions, although the direct correlation between pain and inflammation remains challenging. The prevalence of neuropathies among hypermobile individuals accentuates the discordance between pain perception and thermographic findings, further complicating diagnosis and management. Despite its potential, the clinical integration of IRT faces challenges, with conflicting evidence hindering its adoption. However, studies demonstrate objective temperature disparities between healthy and diseased joints, especially under dynamic thermography, suggesting its potential utility in clinical practice. Future research focused on refining diagnostic criteria and elucidating the underlying mechanisms of hypermobility syndromes will be essential to improve diagnostic accuracy and enhance patient care in this complex and multidimensional context.","PeriodicalId":48617,"journal":{"name":"Yale Journal of Biology and Medicine","volume":"97 2","pages":"225-238"},"PeriodicalIF":2.5,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11202108/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reevaluating Biota Alteration: Reframing Environmental Influences on Chronic Immune Disorders and Exploring Novel Therapeutic Opportunities. 重新评估生物群变化：重塑环境对慢性免疫疾病的影响，探索新的治疗机会。

IF 2.5 3区工程技术

Yale Journal of Biology and Medicine Pub Date : 2024-06-28 eCollection Date: 2024-06-01 DOI: 10.59249/VUNF1315

William Parker, Kateřina Jirků, Esha Patel, Lauren Williamson, Lauren Anderson, Jon D Laman

{"title":"Reevaluating Biota Alteration: Reframing Environmental Influences on Chronic Immune Disorders and Exploring Novel Therapeutic Opportunities.","authors":"William Parker, Kateřina Jirků, Esha Patel, Lauren Williamson, Lauren Anderson, Jon D Laman","doi":"10.59249/VUNF1315","DOIUrl":"10.59249/VUNF1315","url":null,"abstract":"Environmental mismatches are defined as changes in the environment that induce public health crises. Well known mismatches leading to chronic disease include the availability of technologies that facilitate unhealthy diets and sedentary lifestyles, both factors that adversely affect cardiovascular health. This commentary puts these mismatches in context with biota alteration, an environmental mismatch involving hygiene-related technologies necessary for avoidance of infectious disease. Implementation of hygiene-related technologies causes a loss of symbiotic helminths and protists, profoundly affecting immune function and facilitating a variety of chronic conditions, including allergic disorders, autoimmune diseases, and several inflammation-associated neuropsychiatric conditions. Unfortunately, despite an established understanding of the biology underpinning this and other environmental mismatches, public health agencies have failed to stem the resulting tide of increased chronic disease burden. Both biomedical research and clinical practice continue to focus on an ineffective and reactive pharmaceutical-based paradigm. It is argued that the healthcare of the future could take into account the biology of today, effectively and proactively dealing with environmental mismatch and the resulting chronic disease burden.","PeriodicalId":48617,"journal":{"name":"Yale Journal of Biology and Medicine","volume":"97 2","pages":"253-263"},"PeriodicalIF":2.5,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11202117/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Examining the Impact of Social Support on Psychological Well-Being Among Canadian Individuals With COPD: Implications for Government Policies. 研究社会支持对加拿大慢性阻塞性肺病患者心理健康的影响：对政府政策的启示。

IF 2.5 3区工程技术

Yale Journal of Biology and Medicine Pub Date : 2024-06-28 eCollection Date: 2024-06-01 DOI: 10.59249/OKAB8606

Rosina E Mete

{"title":"Examining the Impact of Social Support on Psychological Well-Being Among Canadian Individuals With COPD: Implications for Government Policies.","authors":"Rosina E Mete","doi":"10.59249/OKAB8606","DOIUrl":"10.59249/OKAB8606","url":null,"abstract":"Chronic obstructive pulmonary disease (COPD) is a significant respiratory disease and is globally ranked as the third leading cause of death. In Canada, the direct healthcare costs associated with COPD are estimated to be $1.5 billion annually. This study utilized quantitative analyses to examine the impact of specific dimensions of social support, namely, guidance, reliable alliance, reassurance of worth, attachment, and social integration within a clinically identified population of individuals with COPD who exhibit symptoms of depression and anxiety. The study was based on the Social Provisions Theory and stress-buffering hypothesis, utilizing large-scale population data from Statistics Canada's 2012 Canadian Community Health Survey (CCHS) Mental Health component. On a national scale, individuals were more likely to report a decreased sense of belonging to a group of friends (social integration) and struggle to depend on others in stressful times (reliable alliance) while experiencing symptoms of anxiety and depression. These findings underscore the potential benefits of integrating peer support, socialization initiatives, and caregiver training into clinical programs designed for individuals with COPD.","PeriodicalId":48617,"journal":{"name":"Yale Journal of Biology and Medicine","volume":"97 2","pages":"125-139"},"PeriodicalIF":2.5,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11202116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Suppressor of Cytokine Signaling Proteins 3 and 5 Potentially Delineate Polarization of Th cells in Chronic Rhinosinusitis. 细胞因子信号转导抑制蛋白 3 和 5 有可能划定慢性鼻炎 Th 细胞的极化。

IF 2.5 3区工程技术

Yale Journal of Biology and Medicine Pub Date : 2024-06-28 eCollection Date: 2024-06-01 DOI: 10.59249/HZFN2950

Babak Ghalehbaghi, Hossein Aazami, Majid Khoshmirsafa, Alireza Mohebbi, Pegah Babaheidarian, Nesa Rashidi, Kobra Mokhtarian, Reza Ahmadi, Monireh Kamali, Majid Ponour, Ayda Sanaei, Farhad Seif, Maryam Jalessi

{"title":"Suppressor of Cytokine Signaling Proteins 3 and 5 Potentially Delineate Polarization of Th cells in Chronic Rhinosinusitis.","authors":"Babak Ghalehbaghi, Hossein Aazami, Majid Khoshmirsafa, Alireza Mohebbi, Pegah Babaheidarian, Nesa Rashidi, Kobra Mokhtarian, Reza Ahmadi, Monireh Kamali, Majid Ponour, Ayda Sanaei, Farhad Seif, Maryam Jalessi","doi":"10.59249/HZFN2950","DOIUrl":"10.59249/HZFN2950","url":null,"abstract":"Background: Chronic rhinosinusitis (CRS) is an inflammatory condition classified into chronic rhinosinusitis with nasal polyps (CRSwNP) and chronic rhinosinusitis without nasal polyps (CRSsNP). Th cells manage inflammatory cells in CRS. Suppressor of Cytokine Signaling (SOCS) proteins regulate Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathway in Th cells by polarizing toward Th1, Th2, and Th17 cells. This study evaluated the levels of SOCS1,3,5 in CRS patients to find associations with Th cells. Methods: In this cross-sectional study, 20 CRSwNP patients, 12 CRSsNP patients, and 12 controls participated. The infiltration of CD4+ T cells was determined using immunohistochemistry. The expression of specific transcription factors and SOCS proteins was assessed using real-time PCR. Cytokine levels were evaluated using ELISA. SOCS protein levels were investigated using western blot analysis. Results: The expression of SOCS3 increased in the CRSwNP group compared to CRSsNP and control groups (p <0.001). SOCS3 protein levels increased in the CRSwNP group compared to CRSsNP (p <0.05) and control (p <0.001) groups. Although there was a significant difference in SOCS5 expression between CRSsNP and control groups, SOCS5 protein levels were significantly different between CRSsNP and control (p <0.001) and CRSwNP (p <0.05) groups. Conclusions: Targeted therapies may be suggested for CRS by modulating SOCS3 and SOCS5 proteins that are responsible for polarization of Th cells toward Th2 or Th1 cells, respectively. JAK-STAT pathway targeting, which encompasses numerous cells, can be limited to SOCS proteins to more effectively orchestrate Th cell differentiation.","PeriodicalId":48617,"journal":{"name":"Yale Journal of Biology and Medicine","volume":"97 2","pages":"165-177"},"PeriodicalIF":2.5,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11202107/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cancer to Cataracts: The Mechanistic Impact of Aldo-Keto Reductases in Chronic Diseases. 从癌症到白内障：慢性疾病中醛酮还原酶的机理影响。

IF 2.5 3区工程技术

Yale Journal of Biology and Medicine Pub Date : 2024-06-28 eCollection Date: 2024-06-01 DOI: 10.59249/VTBV6559

Anirudh P Shanbhag, Purnendu Bhowmik

引用次数: 0

Effect of Prenatal Care on Perinatal Outcomes of Pregnant Women with Diabetes Mellitus: A Systematic Review. 产前护理对糖尿病孕妇围产期结果的影响：系统回顾

IF 2.5 3区工程技术

Yale Journal of Biology and Medicine Pub Date : 2024-03-29 eCollection Date: 2024-03-01 DOI: 10.59249/WPTY4075

Letícia B G da Silva, Lenita Zajdenverg, Elisa Keating, Manoela Pereira Smith Silvestre, Beatriz M B Dos Santos, Cláudia Saunders

{"title":"Effect of Prenatal Care on Perinatal Outcomes of Pregnant Women with Diabetes Mellitus: A Systematic Review.","authors":"Letícia B G da Silva, Lenita Zajdenverg, Elisa Keating, Manoela Pereira Smith Silvestre, Beatriz M B Dos Santos, Cláudia Saunders","doi":"10.59249/WPTY4075","DOIUrl":"10.59249/WPTY4075","url":null,"abstract":"Objective: to evaluate the effect of prenatal care (PC) on perinatal outcomes of pregnant women with diabetes mellitus (DM). Methods: systematic review developed according to Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) 2020 guidelines and conducted through the population, intervention, control, and outcomes (PICO) strategy. Clinical trials and observational studies were selected, with adult pregnant women, single-fetus pregnancy, diagnosis of DM, or gestational DM and who had received PC and/or nutritional therapy (NT). The search was carried out in PubMed, Scopus, and BIREME databases. The quality of the studies was evaluated using the tools of the National Heart, Lung and Blood Institute-National Institutes of Health (NHLBI-NIH). Results: We identified 5972 records, of which 15 (n=47 420 pregnant women) met the eligibility criteria. The most recurrent outcomes were glycemic control (14 studies; n=9096 participants), hypertensive disorders of pregnancy (2; n=39 282), prematurity (6; n=40 163), large for gestational age newborns (4; n=1556), fetal macrosomia (birth weight >4kg) (6; n=2980) and intensive care unit admission (4; n=2022). Conclusions: The findings suggest that PC interferes with the perinatal outcome, being able to reduce the risks of complications associated with this comorbidity through early intervention, especially when the NT is an integral part of this assistance.","PeriodicalId":48617,"journal":{"name":"Yale Journal of Biology and Medicine","volume":"97 1","pages":"49-65"},"PeriodicalIF":2.5,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10964819/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140337257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Causes and Effects of COVID-19 Vaccine Hesitancy Among Pregnant Women and its Association with Adverse Maternal, Placental, and Perinatal Outcomes. 孕妇不接种 COVID-19 疫苗的原因和影响及其与孕产妇、胎盘和围产期不良结果的关联。

IF 2.5 3区工程技术

Yale Journal of Biology and Medicine Pub Date : 2024-03-29 eCollection Date: 2024-03-01 DOI: 10.59249/LPOQ5146

Kristen Lee Moriarty, Roselyn O Oyenuga, Olatoyosi Olafuyi, David A Schwartz

引用次数: 0