BMC Sports Science Medicine and Rehabilitation最新文献

{"title":"The effect of the menstrual cycle phases on back squat performance, jumping ability and psychological state in women according to their level of performance -a randomized three-arm crossover study.","authors":"Eduard Isenmann, Steffen Held, Stephan Geisler, Ulrich Flenker, Ian Jeffreys, Christoph Zinner","doi":"10.1186/s13102-024-01010-4","DOIUrl":"10.1186/s13102-024-01010-4","url":null,"abstract":"<p><strong>Objective: </strong>The influence of the menstrual cycle on practical power performance such as barbell back squats and jumping performance in women has not yet been fully investigated. In addition, the performance level of athletes has not been considered in previous studies. This study aimed to investigate the influence of different cycle phases on acute back squat performance, jumping ability and psychological state concerning the performance level.</p><p><strong>Methods: </strong>24 female strength athletes (age: 25.2 ± 3.3 years; height: 169.5 ± 3.4 cm; body weight: 67.7 ± 7.3 kg) were recruited for the study. Level of performance was classified according to Santos et al. (intermittent (n = 13), advanced (n = 6), highly advanced (n = 5)). Participants were tested for 1RM barbell back squat and jumping performance (countermovement and squat jump) as well as two questionnaires assessing their psychological states in the menses (M), late follicular phase (FP) and mid-luteal phase (LP) in three MC. Saliva estradiol and progesterone concentrations with a menstrual cycle diary were used to confirm a normal MC. A principal components analysis for power performance, well-being, relaxation and alertness was carried out and a linear mixed model was used for statistical evaluation.</p><p><strong>Results: </strong>No significant differences were found between the MC phases in performance scores (p > 0.05), readiness (p > 0.05) and alertness (p > 0.05). However, a high correlation between MC phases, performance level and back squat performance was detected. Correlation analyses indicate that a higher performance level results in a higher variation depending on the MC of the squat performance. For well-being, a significantly lower score was detected in M than in FP and LP.</p><p><strong>Conclusion: </strong>In general the performance score of the lower body is not influenced by the MC. If strength performance and jumping ability are considered separately, there are indications that strength capability is influenced at a higher performance level. In addition, individual variance was also observed, so this should also be considered. However, further studies are needed to confirm this assumption due to the small sample sizes of the individual performance levels.</p><p><strong>Trial registration: </strong>German registry for clinical studies (DRKS00034816, Date: 08/01/2024).</p>","PeriodicalId":48585,"journal":{"name":"BMC Sports Science Medicine and Rehabilitation","volume":"16 1","pages":"224"},"PeriodicalIF":2.1,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531699/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142564913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of genetic polymorphism on sports talent performance versus non-athletes: a systematic review and meta-analysis.","authors":"Cirley Pinheiro Ferreira, Valmir Oliveira Silvino, Rebeca Gonçalves Trevisano, Rayane Carvalho de Moura, Sandro Soares Almeida, Marcos Antonio Pereira Dos Santos","doi":"10.1186/s13102-024-01001-5","DOIUrl":"10.1186/s13102-024-01001-5","url":null,"abstract":"<p><strong>Background: </strong>Talented athletes exhibit remarkable skills and performance in their respective sports, setting them apart from their peers. It has been observed that genetic polymorphisms can influence variations in sports performance, leading to numerous studies aimed at validating genetic markers for identifying sports talents. This study aims to evaluate the potential contribution of genetic factors associated with athletic performance predisposition in identifying sports talents.</p><p><strong>Methods: </strong>A systematic review was conducted following the PRISMA framework, utilizing the PICO methodology to develop the research question. The search was limited to case-control studies published between 2003 and June 2024, and databases such as Medline, LILACS, WPRIM, IBECS, CUMED, VETINDEX, Web of Science, Science Direct, Scopus and Scielo were utilized. The STREGA tool was employed to assess the quality of the selected studies.</p><p><strong>Results: </strong>A total of 1,132 articles were initially identified, of which 119 studies were included in the review. Within these studies, 50 genes and 94 polymorphisms were identified, showing associations with sports talent characteristics such as endurance, strength, power, and speed. The most frequently mentioned genes were ACTN3 (27.0%) and ACE (11.3%).</p><p><strong>Conclusion: </strong>The ACE I/D and ACTN3 R577X polymorphisms are frequently discussed in the literature. Although athletic performance may be influenced by different genetic polymorphisms, limitations exist in associating them with athletic performance across certain genotypes and phenotypes. Future research is suggested to investigate the influence of polymorphisms in elite athletes from diverse backgrounds and sports disciplines.</p>","PeriodicalId":48585,"journal":{"name":"BMC Sports Science Medicine and Rehabilitation","volume":"16 1","pages":"223"},"PeriodicalIF":2.1,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11529235/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142559167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The investigation of ultrasound to assess lateral abdominal wall activation with different types of core exercises.","authors":"Nan Hu, Fengshan Huang, Rui Yu, Neil Chen Yi Lun MacAlevey, Yi Zeng, Ping Miao","doi":"10.1186/s13102-024-01009-x","DOIUrl":"10.1186/s13102-024-01009-x","url":null,"abstract":"<p><strong>Background: </strong>Core training is the foundation of physical exercise. The activation of the lateral abdominal wall (LAW) muscles in the core muscles, particularly the transversus abdominal (TrA) muscles, has a stabilizing effect on the chest and abdomen. Therefore, we need to focus on the training effect of the TrA. There are many ways to measure the LAW. Ultrasound can assess the effect of training in real time and intuitively. Therefore, we intend to evaluate the activation of the LAW in different types of core training using ultrasound, to determine the best movements that can activate the TrA and train the core muscles.</p><p><strong>Methods: </strong>22 healthy subjects (male 10, female 12, age 22.82 ± 0.98, BMI 20.78 ± 2.27) were included. The subjects were given the following instructions to perform breathing exercises at different positions: calm breathing and deep breathing at 0° hip flexion and 0° knee flexion; calm breathing, deep breathing, abdominal crunches and ball crunches at 45° hip flexion and 90° knee flexion; and calm breathing, deep breathing, abdominal crunches and ball crunches at 90° hip flexion and 90° knee flexion. The muscle thicknesses of the bilateral transversus abdominis (TrA), internal oblique (IO), external oblique (EO), and LAW muscles were measured using ultrasonography at the end of expiration during the above movements.</p><p><strong>Results: </strong>(1) The action with the greatest contraction ratio of the TrA was deep exhalation, which was significantly greater than crunch and ball crunch; (2) During deep exhalation, the TrA had the greatest contraction ratio, significantly greater than the IO and EO. (3) The TrA was thinnest during deep exhalation at 90°, followed by 45° and 0°.</p><p><strong>Conclusion: </strong>In healthy young people, deep expiration with 90° hip flexion and 90° knee flexion was the optimal action for activating the LAW, especially the TrA.</p>","PeriodicalId":48585,"journal":{"name":"BMC Sports Science Medicine and Rehabilitation","volume":"16 1","pages":"222"},"PeriodicalIF":2.1,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11514915/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142523409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lower limbs kinematic analysis during a jump landing task in soccer players with unilateral anterior cruciate ligament reconstruction.","authors":"Moosareza Ghorbani, Hamed Nouri, Mona Heydarian, Mohammad Mottaghitalab, Hamed Zarei","doi":"10.1186/s13102-024-01012-2","DOIUrl":"10.1186/s13102-024-01012-2","url":null,"abstract":"<p><strong>Background: </strong>Fatigue leads to an acute decline in muscle strength, altered patterns of lower extremity muscle activation, changes in hip and knee kinematics. In terms of the effects of fatigue on knee joint kinematics during plyometric training, there is still a lack of knowledge regarding kinematic differences between athletes who passed the ACL reconstructions rehabilitation period and healthy athletes. Therefore, this study aimed to compare lower limb joint kinematic parameters between reconstructed cruciate ligament and healthy control soccer players during jump landing in a fatigued setting.</p><p><strong>Methods: </strong>Lower limb kinematic parameters were recorded in 20 professional soccer players (age, 24.95 ± 2.92 years; body mass, 77.20 ± 12.88 kg; height, 1.77 ± 3.19 m) during jump landing task before and after the fatigue protocol. The control group consisted of healthy subjects and the experimental group consisted of subjects with ACL reconstruction by thigh transplantation. Kinematic data was recorded with 4 cameras to measure lower limb angles at first foot contact and maximum range of motion.</p><p><strong>Results: </strong>The results showed that before fatigue, there was only a significant difference between the two groups in the maximum range of motion of the non-involved hip joint (P = 0.022) and angle of the involved hip at first contact (P = 0.049). In other data on joint range of motion or initial contact angle, no significant difference was observed between the two groups (P > 0.05). After fatigue protocol, there was a significant difference in initial foot contact in non-involved (P = 0.030), and involved (P = 0.020) hip joint angles between the two groups. However, no significant difference in initial contact angle or range of motion of other joints was observed between the groups.</p><p><strong>Conclusions: </strong>This study shows that plyometric fatigue does not contribute to numerous changes in contact angles and range of motion in lower extremity joints in healthy soccer players and those with a history of cruciate ligament repairs.</p>","PeriodicalId":48585,"journal":{"name":"BMC Sports Science Medicine and Rehabilitation","volume":"16 1","pages":"221"},"PeriodicalIF":2.1,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health-related quality of life among lower limb amputees using prostheses in Nepal: a cross-sectional study.","authors":"Bibek Banskota, Rajan Bhusal, Niraj Bhattarai, Yam Prakash Gurung, Prakash Kumar Yadav, Ashok Kumar Banskota","doi":"10.1186/s13102-024-01008-y","DOIUrl":"https://doi.org/10.1186/s13102-024-01008-y","url":null,"abstract":"<p><strong>Introduction: </strong>Lower limb amputation significantly impacts individuals' quality of life, with prostheses playing a crucial role in rehabilitation and mobility restoration. In Nepal, where access to advanced medical care is limited, understanding the factors affecting the well-being of prosthesis users is essential for optimizing rehabilitation services. This study investigates the sociodemographic and health-related variables influencing the quality of life among lower-limb amputees using prostheses in Nepal.</p><p><strong>Methods: </strong>A cross-sectional study was conducted at a super-specialized disability care center within a tertiary care hospital. The study included 43 amputees who had received prostheses at least five years prior and were regular users. The sample was drawn from patients at the same hospital. The study collected data on sociodemographic characteristics, health components, and pain experiences. Health-related quality of life (HrQoL) was assessed using the SF-12 tool, with scores above 50 indicating high HrQoL on the Mental Component Summary (MCS) and Physical Component Summary (PCS). Scores below 50 indicated low HrQoL. Factors associated with these variables were analyzed using Chi-square (χ²) at a 95% confidence interval.</p><p><strong>Results: </strong>Our study assessed the health-related quality of life among lower limb amputees, finding that 76.74% of participants scored high in mental health and 81.40% in physical health. Significant associations were identified between age and marital status with the Mental Component Summary (MCS) and Physical Component Summary (PCS). Additionally, the reason for amputation and the experience of the Phantom pain were linked to the MCS. Factors like treatment for stump pain, perceived effectiveness of stump pain treatment, and residual stump pain were associated with both the PCS and MCS, while actions taken for stump pain and extremity dominance were associated significantly with the PCS. The level of amputation and treatment for phantom pain also showed significant association. All associations were significant (p > 0.05) at a 95% confidence interval.</p><p><strong>Conclusion: </strong>These findings indicate that age, marital status, extremity dominance, reason for amputation, stump pain treatment, and pain management are critical factors influencing the quality of life among lower limb amputees. The study underscores the need for comprehensive rehabilitation programs incorporating effective pain management, spouse support, and tailored interventions based on individual demographic and clinical characteristics.</p>","PeriodicalId":48585,"journal":{"name":"BMC Sports Science Medicine and Rehabilitation","volume":"16 1","pages":"220"},"PeriodicalIF":2.1,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11494901/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Studies of physical activity and COVID-19 during the pandemic: an updated scoping review.","authors":"Eduardo L Caputo, Danylo J S Costa, Igor M Mariano, Leticia G Lobo, Ana L A Ribeiro, Julia C Gonçalves, Matheus P Freitas, Priccila Zuchinali, Jeferson S Jeronimo, Paula A B Ribeiro, Felipe F Reichert","doi":"10.1186/s13102-024-00967-6","DOIUrl":"10.1186/s13102-024-00967-6","url":null,"abstract":"<p><strong>Background: </strong>This review is an update of the previous study aiming to identify the available evidence related to physical activity (PA) in the context of the coronavirus disease (COVID-19) pandemic.</p><p><strong>Methods: </strong>We searched 6 databases (PubMed, Embase, SPORTDiscus, Scopus, Web of Science, and CINAHL) in April 2024. Medical subject headings and keywords related to PA and COVID-19 were combined to conduct the online search, which covered the period from July 2020 to April 2024.</p><p><strong>Results: </strong>Overall, 49,579 articles were retrieved. After duplicate removal and title, abstract, and full-text screening, 1,976 articles were included in this update. Most of the studies were observational with a cross-sectional design (68.0%). Most of COVID-19 and PA studies came from high-income countries. Most studies explored the changes in PA levels due to the COVID-19 pandemic and its effects on mental health outcomes.</p><p><strong>Conclusion: </strong>Research on PA and COVID-19 prioritized online approach and cross-sectional designs. Most of the evidence identified a decrease in PA levels due to social distancing measures.</p>","PeriodicalId":48585,"journal":{"name":"BMC Sports Science Medicine and Rehabilitation","volume":"16 1","pages":"218"},"PeriodicalIF":2.1,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11492719/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of multicomponent exercise intervention on cardiometabolic risk factors in children and young adults with cerebral palsy: a multiple-baseline trial.","authors":"Tiina Savikangas, Pedro Valadão, Eero A Haapala, Taija Finni","doi":"10.1186/s13102-024-01006-0","DOIUrl":"10.1186/s13102-024-01006-0","url":null,"abstract":"<p><strong>Background: </strong>Adults with cerebral palsy (CP) have a high risk of cardiometabolic diseases. It is unknown whether this risk is elevated in young people with CP and whether exercise can reduce this risk. Therefore, we investigated the effects of the EXErcise for Cerebral Palsy (EXECP) intervention on cardiometabolic risk in children and young adults with CP and compared this risk to typically developing children and young adults (TDs).</p><p><strong>Methods: </strong>Ambulatory male and female participants with spastic CP, aged 9-24 years, and age- and sex-matched TDs without musculoskeletal disorders were recruited. Participants with CP were measured at baseline, after a three-month control period manifesting normal development, and after the three-month strength, gait, and flexibility training intervention. TDs were measured at baseline and after the control period. They did not attend the intervention. Cardiometabolic risk factors included body weight, body fat percentage, and skeletal muscle mass index assessed with bioimpedance; resting systolic and diastolic blood pressure and aortic pulse wave velocity assessed with a non-invasive oscillometric device; fasting plasma high-density and low-density lipoprotein cholesterol, triglyceride, and glucose levels. Data were analyzed with independent samples t-tests and linear mixed-effects models adjusted for sex and age.</p><p><strong>Results: </strong>The study involved 18 participants with CP (13 males, 9-22 year, mean 14.2 ± 4.4) and 17 TDs (12 males, 9-22 year, mean 14.6 ± 4.3). At baseline, participants with CP had a 1.0 (95% confidence interval (CI) [-2.0, -0.0]) kg/m² lower skeletal muscle mass index than TDs. During the control period, no statistically significant between-group differences were observed in the change of any outcome. In the CP group, body weight (β = 1.87, 95% CI [1.04, 2.70]), fat percentage (β = 1.22 [0.07, 2.37], and blood glucose (β = 0.19, 95% CI [0.01, 0.37]) increased, while diastolic blood pressure (β=-2.31, 95% CI [-4.55, -0.06]) and pulse wave velocity (β=-0.44, 95% CI [-0.73, -0.16]) decreased. In the TD group, only body weight increased (β = 0.85, 95% CI [0.01, 1.68]) statistically significantly. In the CP group, no changes were observed during the intervention.</p><p><strong>Conclusions: </strong>Young people with and without CP do not exhibit significant differences in most cardiometabolic risk factors. EXECP intervention may attenuate some adverse development trajectories occurring without the intervention but greater volume and intensity of aerobic exercise may be needed to reduce cardiometabolic risk.</p><p><strong>Trial registration: </strong>ISRCTN69044459; Registration date 21/04/2017.</p>","PeriodicalId":48585,"journal":{"name":"BMC Sports Science Medicine and Rehabilitation","volume":"16 1","pages":"219"},"PeriodicalIF":2.1,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11492564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of 4 weeks of foot exercise on subjective outcome and foot plantar pressure in elite adolescent dancers with hallux valgus: a pilot study.","authors":"Zijian Liu, Yicheng Zhong, Shuo Chen, Hirofumi Tanaka, Yanshu Li, Hirofumi Katsutani, Takumi Okunuki, Hiroki Yabiku, Tsukasa Kumai","doi":"10.1186/s13102-024-01003-3","DOIUrl":"https://doi.org/10.1186/s13102-024-01003-3","url":null,"abstract":"<p><strong>Background: </strong>Dancers have a higher prevalence of hallux valgus (HV) than the general population. However, no reports specifically addressing treatment strategies for HV in dancers, or their effectiveness have been published. This study aimed to determine the effects of 4 weeks of foot exercises on subjective clinical outcomes, the HV angle, and change of foot plantar pressure during specific dance techniques.</p><p><strong>Methods: </strong>Thirteen female elite adolescent dancesport athletes (age: 16.4 ± 3.3 years) completed the program. The HV angle was measured based on foot photographs. Clinical assessments were performed using the visual analog scale for first metatarsophalangeal (1st MTP) joint pain, and the Foot and Ankle Outcome Score. The changes in plantar pressure during two dance techniques (demi-pointe and plié) were measured. The plantar pressure was measured in six areas of the foot. All of these parameters were compared before and after the intervention by using chi-square tests and Student's paired t-test (statistical significance: p < 0.05).</p><p><strong>Results: </strong>The HV angle was significantly reduced from 20.1° to 15.4° after the intervention. Participants reported an average subjective completion rate of 70.3% ± 14.6% over 3 weeks, exhibiting no significant differences despite an apparent trend toward improvement. Significant changes were noted in 1st MTP joint pain and subjective outcomes, and toe function significantly improved in the \"paper\" movement. The foot-exercise program changed plantar pressure distribution during the demi-pointe and plié techniques, with increased hallux pressure and decreased 2nd-5th MTP joint pressure.</p><p><strong>Conclusions: </strong>In elite adolescent dancesport athletes, 4 weeks of foot-exercise rehabilitation reduced the HV angle and improved in subjective outcome and function during the two dance techniques. Coaches should consider utilizing foot-exercise training programs in a dancer training program for HV.</p>","PeriodicalId":48585,"journal":{"name":"BMC Sports Science Medicine and Rehabilitation","volume":"16 1","pages":"217"},"PeriodicalIF":2.1,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11476724/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erythrocyte nicotinamide adenine dinucleotide concentration is enhanced by systematic sports participation.","authors":"Barbara Pospieszna, Krzysztof Kusy, Ewa Maria Slominska, Jacek Zieliński, Monika Ciekot-Sołtysiak","doi":"10.1186/s13102-024-00999-y","DOIUrl":"https://doi.org/10.1186/s13102-024-00999-y","url":null,"abstract":"<p><strong>Background: </strong>Nicotinamide adenine dinucleotide (NAD+), nicotinamide adenine dinucleotide phosphate (NADP+), and their reduced forms (NADH and NADPH) are the vital cofactors for most cellular oxidation/reduction reactions and therefore influence most critical pathways in cellular metabolism. This study aimed to predict the trends of age-related changes in erythrocyte NAD+ and NADP+ concentrations in elite athletes compared to untrained controls and to assess whether life-long physical training stimulates favorable adaptations in erythrocyte NAD(P)+ concentrations.</p><p><strong>Methods: </strong>Erythrocyte concentrations of NAD+ and NADP+ were measured in 68 elite endurance runners (20-81 years), 58 elite sprinters (21-90 years), and 62 untrained individuals (20-68 years). Linear regression analyses were performed to estimate longitudinal relationships and cross-sectional rates of change between age and erythrocyte NAD+ and NADP+ levels. One-way analysis of variance was used to determine differences between the studied groups.</p><p><strong>Results: </strong>In all three groups, the erythrocyte NAD+ and NADP+ concentrations significantly decreased with advancing age, suggesting gradual deterioration of NAD-related regulatory functions in older individuals. However, the concentration of erythrocyte NAD(P)+, regardless of age category, was higher in the athletic groups compared to less active controls.</p><p><strong>Conclusions: </strong>Our research shows that systematic sports participation, especially of a sprint-oriented nature, can be treated as a natural and effective strategy promoting cellular NAD(P)+ anabolism and thus cells' energy and redox metabolism.</p><p><strong>Trial registration: </strong>The study was retrospectively registered in the clinical trials registry on 2021-11-09 (NCT05113914).</p>","PeriodicalId":48585,"journal":{"name":"BMC Sports Science Medicine and Rehabilitation","volume":"16 1","pages":"216"},"PeriodicalIF":2.1,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11476931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of serum 25-hydroxyvitamin D level on quadriceps strength: a systematic review and meta-analysis.","authors":"Michael Tim-Yun Ong, Kitson Chun-Kit Tsang, Victor Yan Zhe Lu, Stacy Lok Sze Yam, Wei Shen, Gene Chi-Wai Man, Patrick Shu-Hang Yung","doi":"10.1186/s13102-024-01007-z","DOIUrl":"https://doi.org/10.1186/s13102-024-01007-z","url":null,"abstract":"<p><strong>Background: </strong>Vitamin D deficiency has been linked to poor muscle function, cartilage degeneration, and the development of knee osteoarthritis. However, the impact of serum 25-hydroxyvitamin D [25(OH)D] level on quadriceps muscle strength remains inconclusive, largely due to variations in study designs, differences in study populations, and the influence of confounding factors such as co-supplementation with other vitamins. The existing literature presents mixed findings, highlighting the need for a comprehensive evaluation of the available evidence.</p><p><strong>Purpose: </strong>This systematic review and meta-analysis aim to summarise.</p><p><strong>Study design: </strong>Systematic review; Level of evidence, 4.</p><p><strong>Methods: </strong>Searches were conducted using Medline (Ovid), Embase (Ovid), CINAHL (EBSCOhost), and SPORTDiscus (EBSCOhost), which aimed to summarise recent (published after 2000 and before March 1st, 2024) studies reporting the effects of serum 25(OH)D levels on quadriceps strength. Appraisal tool for Cross-Sectional Studies (AXIS) for cross-sectional studies and Quality in Prognosis Studies (QUIPS) for longitudinal studies. Results from the AXIS and QUIPS tools were used for GRADE quality assessment. The review was carried out using PRIMSA guidelines and registered in PROSPERO (ID: CRD42022313240).</p><p><strong>Results: </strong>Four hundred studies were screened and 28 studies with 5752 participants were included. 28 published studies (24 cross-sectional and 4 longitudinal) were identified. Key results supported the significant positive correlation between serum 25(OH)D levels and isokinetic quadriceps strength at 180°/s in elderly and athletic populations with a correlation coefficient of 0.245 (95%CI: 0.078-0.398, p = 0.004). However, no significant correlation was found with isometric quadriceps strength or isokinetic strength at 60°/s (r = 0.190, p = 0.085). There was only a weak negative correlation with MVC.</p><p><strong>Conclusion: </strong>This review found a statistically significant positive correlation between serum 25(OH)D levels and isokinetic quadriceps strength. This has important clinical implications, especially in the elderly cohort, with higher 25(OH)D levels being associated with a reduced incidence of falls and fragility fractures.</p>","PeriodicalId":48585,"journal":{"name":"BMC Sports Science Medicine and Rehabilitation","volume":"16 1","pages":"215"},"PeriodicalIF":2.1,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11476103/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}