Behaviour Research and Therapy最新文献

{"title":"Should I stay or should I go? Investigating reward-based decision-making in anhedonic individuals","authors":"Lais B. Razza ,&nbsp;Maud Grol ,&nbsp;Campbell Le Heron ,&nbsp;Glen Boschmans ,&nbsp;Marie-Anne Vanderhasselt ,&nbsp;Rudi De Raedt","doi":"10.1016/j.brat.2025.104782","DOIUrl":"10.1016/j.brat.2025.104782","url":null,"abstract":"<div><h3>Background</h3><div>Anhedonia leads to reduced pleasure and interest, and may result from altered reward-based decision-making processes. Whereas research with anhedonic individuals typically focuses on tasks to choose between options, daily life involves situations where reward rate varies and decisions evolve over time. In this scenario, foraging models provide a framework in which individuals must consider the rewards they are currently receiving (foreground) and weigh them against potential rewards available elsewhere (background/environment).</div></div><div><h3>Methods</h3><div>In this study, we aimed to evaluate reward-based decision making of anhedonic (vs. non-anhedonic) individuals using a foraging task in which optimal decisions are described by a normative model, and investigate whether changes in reward environment could impact the decisions as a function of anhedonia, measured by leaving time and reward at the time of leaving.</div></div><div><h3>Results</h3><div>A total of 94 individuals (mean age = 24yo, SD = 7.85) were allocated to low anhedonic (n = 45; mean MADRS score = 22.1) and high anhedonic (n = 49; mean MADRS score = 36.7) groups. Findings indicate that individuals with higher levels of anhedonia show suboptimal decision-making processes in both leaving time (p = 0.005, η² = 0.064) and reward rate at leaving time (p = 0.005, η² = 0.12). However, contrary to initial hypotheses, these individuals did not demonstrate reduced sensitivity to environmental changes but rather displayed a consistent delay in leaving all patch types.</div></div><div><h3>Conclusion</h3><div>Results suggest that anhedonia is associated with underestimation of the value of the background reward environment, but preserved abilities to utilize reward information for making foraging decisions. This task might be valuable for measuring key constructs within the NIMH Positive Valence Systems domain, including Reward Responsiveness and Reward Valuation.</div></div>","PeriodicalId":48457,"journal":{"name":"Behaviour Research and Therapy","volume":"192 ","pages":"Article 104782"},"PeriodicalIF":4.2,"publicationDate":"2025-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144222810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expanding the toolset of experimental Psychopathology: The Trier Social Stress Test induces a personally relevant emotional memory","authors":"Inga Marie Freund,&nbsp;Jacqueline Peters,&nbsp;Arnold A.P. van Emmerik,&nbsp;Merel Kindt,&nbsp;Renée M. Visser","doi":"10.1016/j.brat.2025.104783","DOIUrl":"10.1016/j.brat.2025.104783","url":null,"abstract":"<div><div>Despite the remarkable progress in developing effective psychological interventions for emotional disorders, our understanding of the mechanisms driving therapeutic change remains strikingly limited. To bridge this gap, we need to refine experimental paradigms with high ecological validity and establish their clinical utility. In this study, we replicate and extend previous findings that the Trier Social Stress Test (TSST) can evoke persistent, sensory rich, and personally meaningful emotional memories. One week after the TSST, a student sample (<em>N</em> = 146) reported greater negative valence, arousal, and lack of control in response to TSST-related versus control cues. Participants reported intrusive memories, the content of which reflects the personal relevance, sensory richness, and emotionality of the TSST memory. Re-imagining the TSST through guided imagery evoked heightened emotional responses (skin conductance, heart rate, and self-report) and participants evaluated themselves more negatively due to the TSST. These effects correlated with trait anxiety. However, comparisons to a naïve sample that only experienced the TSST through guided imagery (<em>N</em> = 38) revealed that some findings, including changes in self-image, were not <em>memory</em>-induced. We conclude with concrete examples of how the paradigm can expand our toolset to further unravel mechanistic underpinnings of memory-focused interventions.</div></div>","PeriodicalId":48457,"journal":{"name":"Behaviour Research and Therapy","volume":"191 ","pages":"Article 104783"},"PeriodicalIF":4.2,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144167159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Network intervention analysis of a digital intervention for the prevention of depression in patients with chronic back pain","authors":"Isaac Moshe ,&nbsp;Jonas Haslbeck ,&nbsp;Yannik Terhorst ,&nbsp;Sarah Paganini ,&nbsp;Sandra Schlicker ,&nbsp;Harald Baumeister ,&nbsp;Lasse B. Sander","doi":"10.1016/j.brat.2025.104784","DOIUrl":"10.1016/j.brat.2025.104784","url":null,"abstract":"<div><div>Depression frequently co-occurs with chronic back pain (CBP), complicating treatment outcomes and increasing healthcare utilization. Digital interventions have demonstrated efficacy for the prevention of major depressive disorder (MDD) in individuals with CBP. However, little is known about how these interventions exert the effects at the symptom level. This was a secondary analysis of a RCT for the prevention of depression in patients with subclinical symptoms of depression and co-occurring CBP. N = 295 participants were randomized to a digital intervention lasting approximately 8 weeks or a treatment-as-usual control (TAU) group. Network analysis was used to examine the multimorbid symptom network structure and the symptom-specific treatment effects of the intervention. Depressive symptoms were assessed by the 9-item patient health questionnaire (PHQ-9) and pain-related disability was measured by the 10-item Oswestry Disability Index (ODI). Network analysis of the symptom networks prior to the intervention revealed that the depressive symptom “energy” was the strongest bridge connecting the communities of depression and pain disability symptoms. The largest influence of the intervention post-treatment was also on the “energy” symptom (PHQ4, -0.18). Additionally, the intervention directly improved “concentration” (PHQ7, -0.13), and “pain intensity” (ODI1, -0.09). The current study highlights the role that the symptom of “energy” may play in multimorbid depression and CBP. It also provides a hypothetical mechanism by which in intervention for the prevention of MDD in patients with CBP exerted its effects. Symptom-level approaches using network analysis may facilitate a deeper understanding of multimorbidity, as well as a framework for developing more targeted, effective interventions.</div></div>","PeriodicalId":48457,"journal":{"name":"Behaviour Research and Therapy","volume":"192 ","pages":"Article 104784"},"PeriodicalIF":4.2,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144205186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A mental imagery intervention targeting suicidal ideation in university students: An assessor-blind, randomised controlled feasibility trial","authors":"Jasper Palmier-Claus ,&nbsp;Paula Duxbury ,&nbsp;Dan Pratt ,&nbsp;Sophie Parker ,&nbsp;Chris Sutton ,&nbsp;Fiona Lobban ,&nbsp;Jane Moorhouse ,&nbsp;Eirian Kerry ,&nbsp;Chloe Russell ,&nbsp;Blessing Nyakutsikwa ,&nbsp;Richard Drake ,&nbsp;Steve Eccles ,&nbsp;Nathan Randles ,&nbsp;Rafeea Patel ,&nbsp;James Kelly ,&nbsp;Rosemary Tattersall ,&nbsp;Peter James Taylor","doi":"10.1016/j.brat.2025.104780","DOIUrl":"10.1016/j.brat.2025.104780","url":null,"abstract":"<div><div>The Broad-Minded Affective Coping (BMAC) intervention is a theory-driven cognitive therapy aiming to reduce suicidal ideation through guided positive mental imagery. We explored the feasibility and acceptability of a randomised controlled trial to evaluate the BMAC intervention in university students. The trial was a two-arm, randomised (ratio 1:1) controlled feasibility trial comparing risk assessment and signposting with or without the BMAC intervention (ISRCTN 13621293; <span><span>ClinicalTrials.gov</span><svg><path></path></svg></span> NCT05296538). Participants had recent suicidal ideation or behaviour. Feasibility outcomes concerned recruitment, retention, intervention adherence, completion of a suicidal ideation assessment, and the safety of the procedures. Clinical outcomes and putative mechanisms were recorded at baseline and after eight, 16, and 24-weeks. All feasibility criteria were met. Sixty-five participants were randomized (99 % of target sample). Retention to follow-up was high at all timepoints (89–91 %). In the treatment arm, 30 out of 33 participants (91 %) attended ≥2 sessions of the BMAC. Retained participants completed a suicidal ideation assessment with no missing data. There were 19 serious adverse events, but none were related to the trial procedures or intervention. Effect estimates for suicidal ideation favoured the intervention. The trial and intervention were acceptable, feasible, and safe. The efficacy of the intervention requires evaluation in a definitive trial.</div></div>","PeriodicalId":48457,"journal":{"name":"Behaviour Research and Therapy","volume":"191 ","pages":"Article 104780"},"PeriodicalIF":4.2,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144123855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examining the efficacy of the computerized anxiety sensitivity treatment in a guided, group format: A randomized controlled trial","authors":"Frederick T. Schubert,&nbsp;Danielle M. Morabito,&nbsp;Norman B. Schmidt","doi":"10.1016/j.brat.2025.104785","DOIUrl":"10.1016/j.brat.2025.104785","url":null,"abstract":"<div><div>Although traditional evidence-based treatments are efficacious in reducing clinical anxiety, many anxious individuals never receive them. Recently, brief technology-based interventions have been developed to overcome access related barriers. Despite their advantages, these interventions also face significant feasibility issues and are underutilized. Adapting digital interventions to be administered in guided, group formats may improve viability and utilization. The current study aimed to evaluate feasibility, acceptability, and efficacy of a brief Cognitive Anxiety Sensitivity Treatment (CAST; Schmidt et al., 2014) administered in groups with the guidance of a clinician. We hypothesized that CAST would be rated as highly acceptable, would significantly reduce anxiety sensitivity when compared to a control intervention, and would retain its mechanism of action on internalizing symptoms such that reductions in anxiety sensitivity (AS) would mediate reductions in symptoms of anxiety and depression. We recruited 73 participants in preexisting groups and groups consisting of individual participants to be randomly assigned to the CAST or control condition with assessments at pre-intervention, post-intervention, and 1-month follow-up. Multilevel linear mixed effect models were conducted to examine whether treatment condition predicts reductions in AS. Direct and indirect effects of intervention condition on internalizing symptoms through changes in AS were examined using regression and mediation models. Results suggest that this “Group CAST” is acceptable and efficacious in reducing AS. Findings suggest Group CAST may reduce depression and anxiety via AS reductions, as with previously studied versions of CAST. Results support a new group-based framework for improving the application of brief digital mental health treatments.</div></div><div><h3>Clinical trial number</h3><div>NCT06817473.</div></div>","PeriodicalId":48457,"journal":{"name":"Behaviour Research and Therapy","volume":"191 ","pages":"Article 104785"},"PeriodicalIF":4.2,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144146998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Direct and indirect effects of a digital Five Ways to Wellbeing intervention: A network intervention analysis","authors":"Monica Beer Prydz ,&nbsp;Ludvig Daae Bjørndal ,&nbsp;Nikolai Olavi Czajkowski ,&nbsp;Espen Røysamb ,&nbsp;Ragnhild Bang Nes","doi":"10.1016/j.brat.2025.104781","DOIUrl":"10.1016/j.brat.2025.104781","url":null,"abstract":"<div><div>While digital positive psychology interventions demonstrate effectiveness in promoting wellbeing and reducing illbeing in the general population, their pathways of change are relatively underexplored. The wellbeing promotive digital intervention, Five Ways to Wellbeing for All (5waysA), has been shown effective (Cohens’ <em>d</em> effect sizes from .20 to .49) in a large (N = 963) randomized controlled trial (Prydz et al., 2024). In the present study, network intervention analysis (NIA) was applied to identify putative direct and indirect effects linking the 5waysA intervention to a set of wellbeing outcomes. Following the 10-week intervention period, the NIA revealed that only positive emotions on an aggregate level were conditionally dependent on the treatment allocation variable. These findings suggest that the effectiveness of the 5waysA intervention primarily reflects the direct enhancement of positive emotions. Our findings provide insights of potential importance for advancing the theoretical framework of the Five Ways to Wellbeing and other mental health and wellbeing promoting interventions.</div></div>","PeriodicalId":48457,"journal":{"name":"Behaviour Research and Therapy","volume":"191 ","pages":"Article 104781"},"PeriodicalIF":4.2,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144131180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unravelling the knot: Investigating avoidance learning in anorexia nervosa","authors":"Michelle Spix,&nbsp;Anita Jansen","doi":"10.1016/j.brat.2025.104779","DOIUrl":"10.1016/j.brat.2025.104779","url":null,"abstract":"<div><div>Restrictive eating – a core symptom of anorexia nervosa (AN) - has been conceptualized as a learned avoidance behaviour driven by anorectic fears. The present study aims to unravel the learning processes contributing to food avoidance in individuals with AN. We expect that 1) individuals with AN acquire aversive conditioned responses for stimuli predicting food intake, 2) learned avoidance behaviours persist when no food is offered anymore and 3) avoidance behaviours initially reduce threat expectancies and fear but maintain conditioned responses long-term. 20 patients with AN and 23 healthy controls (HCs) completed an avoidance learning task with high-calorie food, monetary rewards, and an aversive scream as the unconditioned stimuli (US). Patients showed more avoidance, greater fear, reduced eating desires and less liking for the stimulus predicting food-intake than HCs. After learning that no food was delivered anymore, patients continued to use avoidance behaviours. This prevented a further reduction of US-expectancies and fear. Differences in learning between patients and HCs were specific to the US-food. These findings suggest that learned food avoidance is persistent and hinders the extinction of eating-related threat beliefs and fears. Consequently, interventions for AN focusing on the reduction of fear e.g., exposure therapy, should also address avoidance behaviours.</div></div>","PeriodicalId":48457,"journal":{"name":"Behaviour Research and Therapy","volume":"192 ","pages":"Article 104779"},"PeriodicalIF":4.2,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144204648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The benefit and neural mechanisms of computerized inhibitory control training for insomnia with short sleep duration phenotype: a rs-fMRI study","authors":"Haobo Zhang ,&nbsp;Zhangwei Lv ,&nbsp;Hanfei Chen ,&nbsp;Zijie Tang ,&nbsp;Xu Lei","doi":"10.1016/j.brat.2025.104776","DOIUrl":"10.1016/j.brat.2025.104776","url":null,"abstract":"<div><h3>Background</h3><div>Inhibitory control (IC) impairment is characteristic of insomnia disorder with short sleep duration (ISSD), but not with normal sleep duration (INSD). IC is critical for sleep-wake regulation. This study evaluates whether computerized IC training can improve sleep in ISSD and explores related neural mechanisms using resting-state fMRI (rs-fMRI).</div></div><div><h3>Methods</h3><div>Twenty ISSD patients participated in a three-week computerized IC training program (15 sessions), alongside a control group of 17 participants. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI) and the Insomnia Severity Index (ISI), complemented by objective measures from overnight EEG recordings. Neuroimaging analyses focused on changes in regional homogeneity (ReHo), fractional amplitude of low-frequency fluctuations (fALFF), and functional connectivity (FC) in brain regions associated with IC.</div></div><div><h3>Results</h3><div>Computerized IC training led to significant improvements in both subjective and objective sleep quality, demonstrated by reductions in PSQI and ISI scores, as well as decreased wake time during sleep. Neuroimaging revealed increased ReHo in the left medial orbitofrontal cortex (MOFC), elevated fALFF in the right middle frontal gyrus (MFG), and enhanced FC between the MOFC and the right rectus gyrus (RG), which correlated with improvements in sleep measures.</div></div><div><h3>Conclusion</h3><div>Computerized IC training appears to be an effective intervention for improving sleep in ISSD, likely by inducing functional changes in prefrontal cortex regions. These findings underscore the potential of IC-targeted treatments for ISSD and highlight the need for future research to evaluate the long-term effects of such interventions.</div></div><div><h3>Trial registration</h3><div>The study was prospectively registered on May 30, 2024, in Chinese Clinical Trials registry (ChiCTR2400085063).</div></div>","PeriodicalId":48457,"journal":{"name":"Behaviour Research and Therapy","volume":"191 ","pages":"Article 104776"},"PeriodicalIF":4.2,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144088797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maximizing benefits from evidence-based psychological treatments: Memory support and habit formation as key strategies","authors":"Allison G. Harvey","doi":"10.1016/j.brat.2025.104767","DOIUrl":"10.1016/j.brat.2025.104767","url":null,"abstract":"<div><div>Evidence-based psychological treatments (EBPTs) aim to reverse psychological processes that contribute to the development and/or maintenance of mental illness. Developed and rigorously tested through scientific research, EBPTs effectively address a broad range of mental health challenges, often as front-line treatments. However, there is potential to further improve outcomes. This paper examines two strategies for maximizing the benefits of EBPTs. The first addresses the concerning and well replicated finding that patients accurately recall only about one-third of the treatment points discussed during a session. This poor memory for treatment negatively impacts adherence to the EBPT and outcomes from the EBPT. The process of developing and testing the Memory Support Intervention (MSI), to improve patient memory for treatment, is described. The latter involved leveraging findings from cognitive psychology and education to develop memory support strategies to add to EBPTs, with the goal of improving EBPT outcomes. The second strategy for maximizing the benefits of EBPTs highlights the potential of habit formation principles to enhance EBPTs. While a core goal of EBPTs is to reduce unhelpful habits and encourage adaptive ones, the science of habit formation has not been fully integrated. The Habit-based Intervention (HABITs) was developed to explicitly incorporate habit formation elements into EBPTs. Both the MSI and HABITs are designed as adjunctive interventions, enhancing EBPTs without increasing the number or duration of sessions. This paper concludes by emphasizing the importance of leveraging insights from diverse fields of basic science to uncover new strategies for improving both the short- and long-term outcomes of EBPTs.</div></div>","PeriodicalId":48457,"journal":{"name":"Behaviour Research and Therapy","volume":"191 ","pages":"Article 104767"},"PeriodicalIF":4.2,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144088859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"It's the content of the feedback that matters, not the person giving it: An experimental study on change of negative performance expectations","authors":"Tobias Kube ,&nbsp;Winfried Rief ,&nbsp;Anna Seewald","doi":"10.1016/j.brat.2025.104768","DOIUrl":"10.1016/j.brat.2025.104768","url":null,"abstract":"<div><div>Previous research on biased expectation change has mainly focused on the mechanisms underlying the deficient processing of novel positive information at the individual level. Yet, it is less clear whether also characteristics of the person who provides new learning experiences influence the modification of negative expectations. To approach this question, we tested whether the perceived warmth and competence of a person who provides positive performance feedback influences the extent to which performance expectations change. Participants from a non-clinical sample (<em>N</em> = 146) were randomly assigned to one of three experimental conditions which manipulated the experimenter's interpersonal behaviour in terms of warmth and competence: augmented, limited, control group (minimal physical contact). All participants received the same positive feedback for their performance in an emotion recognition test. Warmth and competence were successfully manipulated, with large effects, but this did not lead to differences in expectation change. Instead, positive post-feedback expectations were associated with low cognitive immunisation and high perceived cognitive value of the feedback across groups. The findings suggest that changing negative performance expectations through positive feedback is possible and mainly depends on the perception of the content of the feedback, while characteristics of the feedback-providing person are less relevant.</div></div>","PeriodicalId":48457,"journal":{"name":"Behaviour Research and Therapy","volume":"191 ","pages":"Article 104768"},"PeriodicalIF":4.2,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143949108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}