{"title":"Bilateral Male Breast Cancer : A Report Case","authors":"","doi":"10.54289/jcrmh2400147","DOIUrl":"https://doi.org/10.54289/jcrmh2400147","url":null,"abstract":"Breast cancer occurs in men, and its rate of incidence has increased recently. The main particularity of men's breast cancer is that its prognosis is usually worse than that of women, because it is diagnosed late and hence at advanced stage. Bilateral involvement has been reported only in rare cases. We report a case of a bilateral breast cancer, in a 47 year old patient , with no family history of breast cancer , who presented with a bilateral breast mass. Histopathological biopsy showed a bilateral invasive carcinoma, Luminal B, HER 2 negative . The extension PET scan showed no distant metastases. Bilateral mastectomy and bilateral sentinel lymph node were performed. The final histopathological exam confirmed the previous biopsy diagnostic, the tumors were mutually classified T2N0M0 of the TNM breast cancer classification. The surgical treatment was followed by tamoxifen hormonotherapy and an oncological semestriel follow-up. No recurrences or relapses were reported. The aim of our current work is to draw attention to this pathology in men, in order to contribute to its early diagnosis and therefore to improve its prognosis.","PeriodicalId":484263,"journal":{"name":"Journal of Case Reports and Medical History","volume":" 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141829259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acute Myeloblastic Leukemia Discovered in the 3rd Trimester of Pregnancy","authors":"","doi":"10.54289/jcrmh2400148","DOIUrl":"https://doi.org/10.54289/jcrmh2400148","url":null,"abstract":"Acute leukemia (AL) rarely occurs during pregnancy. Its incidence is estimated at 1/100 000 pregnancies. In 2/3 of the cases, it is acute myeloblastic leukemia (AML). The dilemma is between chemotherapy which should not be delayed for a better therapeutic prognosis and a foetus at risk of malformation or morbidity and mortality by induced prematurity. We report the observation of a 25-year-old patient in whom we diagnosed AML occurring during a pregnancy at 35 weeks of amenorrhea, and who benefited from obstetrical management then chemotherapy.","PeriodicalId":484263,"journal":{"name":"Journal of Case Reports and Medical History","volume":" 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141830260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Conjoined Thoracopagus Siames Twins : A Case Report from the Casablanca University Hospital","authors":"","doi":"10.54289/jcrmh2400138","DOIUrl":"https://doi.org/10.54289/jcrmh2400138","url":null,"abstract":"Conjoined twins are a particularly rare condition, requiring perfect understanding of their anatomy and multidisciplinary intervention to free them from their attachments. Thoracopagus twins are connected by the chest and umbilicus and are the most common of all variants, but have a low survival rate. We report the case of a 18-year-old female patient, pregnant at 12 weeks amenorrhoea, who consulted in the maternity emergency department with a clinical picture of a miscarriage in the process of expulsion of a conjoined thoracopagus siames twins.","PeriodicalId":484263,"journal":{"name":"Journal of Case Reports and Medical History","volume":" 42","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141827883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Rare Case of an Autoimmune Polyglandular Syndrome Type 2 During Pregnancy","authors":"","doi":"10.54289/jcrmh2400135","DOIUrl":"https://doi.org/10.54289/jcrmh2400135","url":null,"abstract":"Autoimmune polyglandular syndromes (APS) are a rare heterogeneous disorders characterized by combining two or more organ-specific endocrinopathies. During pregnancy, only a few cases of these syndromes have been described. We report a case of autoimmune polyglandular syndrome type 2 presenting during pregnancy and complicated in the immediate postpartum by a severe polyserositis.","PeriodicalId":484263,"journal":{"name":"Journal of Case Reports and Medical History","volume":" 26","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141829750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ovarian Torsion During A 14 Weeks Pregnancy: A Case Report","authors":"","doi":"10.54289/jcrmh2400141","DOIUrl":"https://doi.org/10.54289/jcrmh2400141","url":null,"abstract":"Ovarian torsion during pregnancy is a relatively uncommon emergency presenting with acute pelvic pain, the torsion of the ovary during pregnancy is a rare complication. Clinical symptoms are often non-specific. Pelvic ultrasound remains the gold standard investigation. Laparoscopy is recommended in young pregnancies. We report the case of a 23-year-old female patient, pregnant at 14 weeks amenorrhoea, who presented with pain in the right iliac fossa and who was found to have a torsion of the right ovary on pelvic ultrasound. Exploration showed an increased torsion of the right ovary around the pedicle at 360°, an oophoropexy was performed.","PeriodicalId":484263,"journal":{"name":"Journal of Case Reports and Medical History","volume":" 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141829063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Synchronous Endometrial and Ovarian Cancers: One Case Report","authors":"","doi":"10.54289/jcrmh2400146","DOIUrl":"https://doi.org/10.54289/jcrmh2400146","url":null,"abstract":"Synchronous ovarian and endometrial cancer (SEOC) is a rare instance butit accounts for 50–70% of all synchronous female genital tract tumors We report a case of a woman that was diagnosed with SEOC and underwent surgical staging. Patients with synchronous cancers have better prognosis than those with single disseminated cancer. Their detection in a relatively early stage suggests diagnosis may be facilitated by early symptoms from the endometrial carcinoma, and that these lesions are biologically of relatively low grade. The first symptoms reported by our patients and the course of the disease were concordant with data from the literature.","PeriodicalId":484263,"journal":{"name":"Journal of Case Reports and Medical History","volume":" 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141832511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Ocular Chloramphenicol Story","authors":"","doi":"10.54289/jcrmh2400131","DOIUrl":"https://doi.org/10.54289/jcrmh2400131","url":null,"abstract":"Chloramphenicol eye drops and ointment are the most used ocular antibiotic worldwide. Chloramphenicol was discovered in 1947 and was only the third antibiotic to successfully be produced and only the first antibiotic suitable for large-scale commercial production. By the 1950s, the drug had been developed into drop and ointment forms. The broad spectrum of anti-bacterial activity of Chloramphenicol led to widespread use. Ocular Chloramphenicol remains an important weapon in the ophthalmic armamentarium despite emergence of evidence of possible side effects in the 1970s. This is a short review of the remarkable story of the discovery, development and tribulations of ocular Chloramphenicol. Keywords: History; Chloramphenicol Abbreviations: FDA: Food and Drug Administration","PeriodicalId":484263,"journal":{"name":"Journal of Case Reports and Medical History","volume":"39 29","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141103720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"COVID-19 in Patients with CVID: Retrospective Study During the Pandemic","authors":"","doi":"10.54289/jcrmh2400132","DOIUrl":"https://doi.org/10.54289/jcrmh2400132","url":null,"abstract":"Common Variable Immunodeficiency (CVID) is a genetic disorder characterized by impaired function of T and B lymphocytes, leading to reduced antibody production and immune deficiency. Patients experience recurrent severe infections due to their weakened immune system. The article presents a retrospective study on patients with CVID during the COVID-19 pandemic. The study revealed that patients with CVID, with an average age of 27 years and a male majority, presented varied COVID-19 symptoms, ranging from classic flu-like syndrome to more severe respiratory symptoms. Although 40% of patients received two doses of COVID-19 vaccine, none required hospitalization, and all recovered favorably. Treatments administered included azithromycin, paracetamol, vitamin D, and zinc, in addition to regular immunoglobulins.","PeriodicalId":484263,"journal":{"name":"Journal of Case Reports and Medical History","volume":"31 39","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141104151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acute Pyelonephritis with Renal Vein and Inferior Vena Cava Thrombosis: A Case Report","authors":"","doi":"10.54289/jcrmh2400133","DOIUrl":"https://doi.org/10.54289/jcrmh2400133","url":null,"abstract":"Acute pyelonephritis might be complicated by the formation of renal and perirenal abscesses and very rarely by renal vein thrombosis (RVT), which is a life-threatening condition. We report a case of 35-year-old female with no significant past medical history, who presented a week history of fever, hematuria, flank pain, and lower urinary tract symptoms. Physical examination showed a shivering young woman with fever 39°C of temperature, left flank pain and tenderness was observed on palpation. Laboratory test results showed elevated CRP level at 210 mg/L, white blood cell count at 23000/mm3 with 14000/mm3 neutrophil. Urinalysis showed pyuria, bacteriuria and nitrites presence. Urine cultures grew Escherichia coli and blood cultures were sterile. Unfortunately, after 2 days of antibiotic therapy the patient flank pain worsened, and further imaging evaluation with Abdominal CT scan showed extensive thrombosis of the left renal vein and its branches protruding to the inferior vena cava. The patient improved after intravenous antibiotics and anticoagulation treatment. At 1-month follow-up, the patient was asymptomatic. At 3 months follow-up, CECT showed complete resolution of the IVCT and attenuated renal vein with atrophic small kidney. In conclusion, renal venous thrombosis secondary to acute pyelonephritis is very rare. It is very important to treat it rapidly because it can lead to pulmonary embolism, thrombosis of the inferior vena cava or renal failure, thus jeopardizing the patient's vital and functional prognosis.","PeriodicalId":484263,"journal":{"name":"Journal of Case Reports and Medical History","volume":"69 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141110325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bilateral High-Riding Jugular Bulb and Jugular Diverticulum Dehiscents into the Mastoid cells and Trautmann’s Triangle","authors":"","doi":"10.54289/jcrmh2400105","DOIUrl":"https://doi.org/10.54289/jcrmh2400105","url":null,"abstract":"High-riding jugular bulb is a common abnormality that involves the jugular bulb. It corresponds to a jugular bulb higher than a specific anatomical landmark, which is still controversial. A diverticulum may grow up from the jugular bulb dome in different directions. The jugular bulb may be well-corticated or, on the contrary, dehiscent when the bony cover is deficient. All these anatomical conditions may still be asymptomatic or provoke debilitating symptoms or surgical complications. In this case report, we present a 30-year-old man who suffered from debilitating vertigo and pulsatile tinnitus that hindered his quality of life. Temporal bone high-resolution computed tomography revealed bilateral high-riding jugular bulb, right jugular diverticulum, and right-side dehiscence into the mastoid cells and Trautmann’s triangle. The patient was managed conservatively but without significant symptom relief. This case report highlights an uncommon presentation of dehiscent high-riding jugular bulb and jugular diverticulum that, to the best of our knowledge, has not been reported before.","PeriodicalId":484263,"journal":{"name":"Journal of Case Reports and Medical History","volume":"4 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139439273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}