COVID-19 in Patients with CVID: Retrospective Study During the Pandemic

Abstract

Common Variable Immunodeficiency (CVID) is a genetic disorder characterized by impaired function of T and B lymphocytes, leading to reduced antibody production and immune deficiency. Patients experience recurrent severe infections due to their weakened immune system. The article presents a retrospective study on patients with CVID during the COVID-19 pandemic. The study revealed that patients with CVID, with an average age of 27 years and a male majority, presented varied COVID-19 symptoms, ranging from classic flu-like syndrome to more severe respiratory symptoms. Although 40% of patients received two doses of COVID-19 vaccine, none required hospitalization, and all recovered favorably. Treatments administered included azithromycin, paracetamol, vitamin D, and zinc, in addition to regular immunoglobulins.