Research in Social & Administrative Pharmacy最新文献

{"title":"Health Belief Model Interventions in Pre-exposure Prophylaxis (PrEP): Untapped intervention in the pharmacy arena","authors":"Alina Cernasev ,&nbsp;Holly Angell ,&nbsp;Karen Derefinko ,&nbsp;Santosh Kumar ,&nbsp;Theodore Cory","doi":"10.1016/j.sapharm.2025.09.005","DOIUrl":"10.1016/j.sapharm.2025.09.005","url":null,"abstract":"<div><div>The human immunodeficiency virus (HIV) epidemic continues to be a major public health crisis in the United States. Although pre-exposure prophylaxis (PrEP) has emerged as an effective tool to prevent HIV transmission, its uptake and adherence remain suboptimal, especially among high-risk populations. This article explores how the Health Belief Model (HBM) can serve as a guiding framework for pharmacists and other healthcare professionals to enhance PrEP delivery and patient engagement.</div><div>Recent literature highlights persistent barriers to PrEP use, including stigma, perceived risk, misinformation, and healthcare access challenges. The five core components of the HBM—perceived severity, perceived susceptibility, perceived benefits, perceived barriers, and cues to action—have been used to understand and design interventions across multiple health behaviors. Studies suggest these components are useful in explaining patient behavior and provider limitations around PrEP, particularly in marginalized communities. While few studies directly apply HBM to PrEP adherence, evidence from related fields supports its predictive power.</div><div>The HBM offers a promising lens through which pharmacy-based interventions can be developed to address patient beliefs, reduce stigma, and increase PrEP uptake and adherence. Pharmacists, given their accessibility and trusted role in the community, are uniquely positioned to lead these efforts. Incorporating culturally responsive, HBM-informed strategies in pharmacy practice can significantly improve health outcomes in populations most affected by HIV.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"22 1","pages":"Pages 171-177"},"PeriodicalIF":2.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145208063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and psychometric evaluation of knowledge, attitude, and behavior questionnaire on fall risk–increasing drugs (KABQ-FRID)","authors":"Laksmi Maharani ,&nbsp;Adi Yugatama ,&nbsp;Dedik Sulistiawan ,&nbsp;Shu-Chun Lee","doi":"10.1016/j.sapharm.2025.08.013","DOIUrl":"10.1016/j.sapharm.2025.08.013","url":null,"abstract":"<div><h3>Background</h3><div>Fall risk–increasing drugs (FRIDs) increase the risks of falls, injuries, and fractures among older adults. However, limited evidence exists on how older adults perceive and manage FRID use, particularly in Indonesia.</div></div><div><h3>Objective</h3><div>This study developed and psychometrically evaluated a questionnaire for assessing knowledge, attitudes, and behaviors (KABs) related to FRID use (hereafter KABQ-FRID) among older adults.</div></div><div><h3>Methods</h3><div>KABQ-FRID was developed through a three-stage process. The first stage involved defining a conceptual framework and generating items based on a literature review, team discussions, and expert meeting. The second stage included an expert panel review and assessment of face validity. The third stage involved psychometric testing with 100 older adults receiving medications from a public health center in Surakarta City, Indonesia. Data analysis included Mokken scale analysis, confirmatory factor analysis (CFA), construct validity assessment, and reliability testing.</div></div><div><h3>Results</h3><div>The final KABQ-FRID comprised 21 items across 3 dimensions: knowledge (7 items), attitude (5 items), and behavior (9 items). Psychometric evaluation demonstrated acceptable scalability for all items (Loevinger's H ≥ 0.30) and strong reliability (Cronbach's α &gt; 0.7; intraclass correlation coefficient &gt;0.9). CFA results revealed a χ²/df of 2.0, suggesting a reasonable model fit; all dimensions exhibited satisfactory loadings. Construct validity testing demonstrated strong convergent validity; 90.5 % of the items had a correlation coefficient of &gt;0.4, and 100 % of the items had stronger correlations within their dimensions than with other constructs.</div></div><div><h3>Conclusion</h3><div>KABQ-FRID is a reliable and valid instrument for assessing KAB related to FRID use among community-dwelling older adults.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"22 1","pages":"Pages 152-161"},"PeriodicalIF":2.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145030885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How are prescribing cascades defined in the literature? A scoping review","authors":"Kieran Dalton ,&nbsp;Perrine Evrard ,&nbsp;Frank Moriarty ,&nbsp;Aislinn O'Mahony ,&nbsp;Rachael Horan ,&nbsp;Stephen Byrne ,&nbsp;Lisa M. McCarthy","doi":"10.1016/j.sapharm.2025.07.001","DOIUrl":"10.1016/j.sapharm.2025.07.001","url":null,"abstract":"<div><h3>Introduction</h3><div>Prescribing cascades are important medication-related issues to be aware of, particularly for multimorbid older adults with polypharmacy. These cascades were initially defined as phenomena where side effect misinterpretation results in the prescribing of additional medications. This definition has been debated though, particularly on whether side effects may be misinterpreted or recognised/unrecognised, and consequently whether cascades are intentional/unintentional. Given these inconsistencies, this scoping review aimed to map how prescribing cascades have been defined and described in the published literature.</div></div><div><h3>Methods</h3><div>Seven electronic databases were searched from inception to October 2024. Full-text publications in English that mentioned prescribing cascade (or a synonym) in the title or abstract and provided a prescribing cascade definition/description in the full text were included. Specific terminology and images used to define/describe prescribing cascades were extracted, and the findings were narratively synthesised.</div></div><div><h3>Results</h3><div>Of the 139 included publications, less than half directly aligned with the original definition by containing descriptions of prescribing cascades that indicated side effect misinterpretation (48.9%). One quarter indicated side effects could be recognised or unrecognised (24.5%), 37.4% addressed cascade appropriateness or inappropriateness, and 8.6% referenced their intentional or unintentional nature. One fifth (20.9%) included an image or map to describe a prescribing cascade.</div></div><div><h3>Conclusion</h3><div>This review has uniquely mapped how prescribing cascades have been described in the literature, finding substantial heterogeneity between publications. By highlighting this inconsistent terminology use, this review emphasises the need to develop consensus definitions to aid in the future recognition, measurement, education, and prevention of prescribing cascades.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"21 12","pages":"Pages 1042-1049"},"PeriodicalIF":2.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of pharmacist-led interventions in improving gout outcomes: A systematic review","authors":"Maria Tanveer ,&nbsp;Azhar Hussain Tahir ,&nbsp;Sunil Shrestha ,&nbsp;Muhammad Zawwad Raza ,&nbsp;Ali Ahmed","doi":"10.1016/j.sapharm.2025.06.108","DOIUrl":"10.1016/j.sapharm.2025.06.108","url":null,"abstract":"<div><h3>Background</h3><div>Pharmacists are core members of the healthcare team, offering essential support beyond dispensing of medications. They play a crucial role in managing and educating patients, particularly those with chronic diseases. Although numerous studies have reported the involvement of pharmacists in the care of people living with gout, the overall evidence remains limited and is not well defined.</div></div><div><h3>Objectives</h3><div>This systematic review aims to evaluate the impact of pharmacist-led interventions in improving gout outcomes in people living with gout, specifically focusing on serum uric acid levels, medication adherence, and patient education.</div></div><div><h3>Methods</h3><div>A comprehensive search was conducted on multiple electronic databases including PubMed, Ovid Embase and Cochrane (library) central to identify relevant studies published up to April 2025. The studies eligible for this review included randomized controlled trials (RCTs), and non-randomized studies (non-RCTs), including pre-post studies and cohort designs that assessed pharmacist-led interventions in the management of gout. Outcomes of interest were reductions in serum uric acid levels, prevention of gout flares, absolute serum uric acid reductions, required dosage to achieve target serum uric acid level, improvements in patient education and frequency of clinic visits. The risk of bias for RCTs was assessed by utilizing the ROB-2 tool, while non-randomized studies were assessed with the ROBINS-I tool.</div></div><div><h3>Results</h3><div>Five studies involving a total of 1805 people living with gout were included in this review. In these studies, pharmacists delivered interventions such as provided interventions; enhancing patient education or providing pharmaceutical care either alone or in collaboration with other healthcare team members were included. Two studies were RCTs, while three were non-RCTs. Pharmacist-led interventions contributed to achieving target serum uric acid levels, determining appropriate the dose of urate lowering therapy needed to attain target levels, improving adherence, and reducing gout flares. The randomized trials were found to have lower risk compared to non-randomized studies.</div></div><div><h3>Conclusion</h3><div>The findings suggested that pharmacist involvement in gout management can considerably enhance disease control and improve the overall quality of life for patients. Further research is warranted to identify the most effective components of pharmacist-led interventions and to evaluate their effect on gout outcomes.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"21 12","pages":"Pages 975-990"},"PeriodicalIF":2.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144561555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacist prescribing in cancer services: A scoping review","authors":"L. Johnson ,&nbsp;S. Khattab ,&nbsp;J. Strawbridge ,&nbsp;C. Cadogan ,&nbsp;D. Stewart ,&nbsp;A.M. De Frein ,&nbsp;J. Eustace-Cook ,&nbsp;M.A. Lowrey ,&nbsp;A.M. Brady ,&nbsp;S. Harding ,&nbsp;J. O'Connell ,&nbsp;C. Ryan","doi":"10.1016/j.sapharm.2025.05.004","DOIUrl":"10.1016/j.sapharm.2025.05.004","url":null,"abstract":"<div><h3>Background</h3><div>Pharmacist prescribing (PP) is embedded in clinical practice in various countries, and for a range of clinical conditions. PP occurs in cancer services, but there is limited information describing its extent and impact.</div></div><div><h3>Aim</h3><div>This scoping review aimed to explore PP in cancer services, prescribing models used, impact on patient outcomes and stakeholders’ views.</div></div><div><h3>Method</h3><div>The Joanna Briggs Institute's scoping review guidelines were followed. The population-concept-context framework guided inclusion (population: patients with cancer; concept: pharmacist prescribing; context: cancer services in any care setting). All research articles were eligible for inclusion. Case reports/series, commentaries, articles not in English, were excluded.</div><div>Embase, Scopus, Google Scholar, Web of Science and CINAHL were searched using a combination of search terms e.g. ‘pharmacist prescribing’, ‘nonmedical prescribing’, ‘cancer’, ‘oncology. Titles, abstracts and full texts were reviewed independently by two researchers, disagreements were resolved by discussion and results were narratively synthesised.</div></div><div><h3>Results</h3><div>2453 titles and abstracts were screened, 461 full-texts were reviewed, 41 were included, published between 2008 and 2023. When setting was described, PP was described in tertiary (n = 35), primary (n = 2) and secondary care (n = 1). Various PP models were described, including collaborative prescribing models (PP within protocols agreed with a physician), independent prescribing and supplementary prescribing (PP within a clinical management plan agreed by a physician and patient). All models demonstrated improvement in patient outcomes, adherence, and patient experiences (e.g. reduced time in clinic). Patients and physicians expressed initial reservation, but were largely supportive. Pharmacists reported enhanced job satisfaction. In order to effect change in prescribing practices, regulatory changes, advanced education and training and stakeholder engagement were required.</div></div><div><h3>Conclusion</h3><div>Collaborative prescribing models are the most commonly described PP models used in cancer services. There is potential for expanding pharmacists’ scope of practice in cancer services where this is not routine.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"21 12","pages":"Pages 951-974"},"PeriodicalIF":2.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insights into community pharmacists’ behavioural intention towards providing safe medication disposal service using the theory of planned behaviour","authors":"Sheng Yuan Hiew ,&nbsp;Bee Yean Low ,&nbsp;Kian Wah Liew ,&nbsp;Wah Yun Low ,&nbsp;Kang Nee Ting ,&nbsp;Matthew Boyd","doi":"10.1016/j.sapharm.2025.06.111","DOIUrl":"10.1016/j.sapharm.2025.06.111","url":null,"abstract":"<div><h3>Background</h3><div>Household pharmaceutical waste disposal in Malaysia is inadequate, largely due to limited awareness and a lack of safe disposal facilities. Community pharmacies are not legally required to collect unused or expired medications and face various challenges in offering disposal services. Therefore, it is essential to investigate the factors influencing community pharmacists’ intention to provide safe medication disposal.</div></div><div><h3>Objectives</h3><div>This study aims to identify the attitude, subjective norm and perceived behavioural control affecting Malaysian community pharmacists’ intention to provide medication take-back service and to identify the predictors of this intention.</div></div><div><h3>Methods</h3><div>A cross-sectional survey was conducted with a stratified random sample of 424 community pharmacists in the Klang Valley. The Theory of Planned Behaviour (TPB) served as the theoretical framework, with constructs measured using a 4-point Likert scale. Partial Least Squares Structural Equation Modeling (PLS-SEM) was used to analyse how TPB constructs and external factors influence pharmacists' intention.</div></div><div><h3>Results</h3><div>Of the 424 surveys, 310 responses were received (response rate: 73.1 %). The PLS-SEM model explained 66 % of the variance in pharmacists' intention (R² = 0.662, adjusted R² = 0.656). While attitude was not a significant predictor, subjective norm e.g. patient demand and external factors e.g. business competitiveness were significant positive predictors. Conversely, perceived behavioural control factors, including workload, costs, space and authority negatively impacted intention.</div></div><div><h3>Conclusions</h3><div>This study identifies key constructs influencing community pharmacists' intention to offer medication take-back service. A multifaceted approach involving clear regulatory frameworks, government support and pharmaceutical industry participation, and public education is necessary to enhance this intention.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"21 12","pages":"Pages 1059-1069"},"PeriodicalIF":2.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144601921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancing pharmaceutical practice: Promoting organizational health literacy to improve medication use through an intersectoral model based on the preventive medicine framework","authors":"Francisco Javier Ferreira-Alfaya,&nbsp;Yasmin Cura,&nbsp;María José Zarzuelo-Romero","doi":"10.1016/j.sapharm.2025.08.003","DOIUrl":"10.1016/j.sapharm.2025.08.003","url":null,"abstract":"<div><h3>Background</h3><div>Health Literacy remains insufficiently developed in many populations, leading to suboptimal health outcomes and increased socio-economic burden. Despite lying at the intersection of educational and healthcare sectors, Health Literacy interventions are hindered by persistent institutional disconnect. Pharmacists, due to their accessibility and expertise in medication use, are well-positioned to bridge this gap and support intersectoral strategies to improve patient outcomes.</div></div><div><h3>Objectives</h3><div>This study proposes a pharmacist-led model of Organizational Health Literacy, grounded in current recommendations and identified systemic gaps.</div></div><div><h3>Methods</h3><div>A pharmacist-led model was developed through a narrative synthesis of the literature, incorporating current recommendations, conceptual frameworks, and identified gaps in the implementation of Organizational Health Literacy across healthcare and educational systems. The preventive medicine model by Leavell and Clark was adapted to structure the intersectoral approach.</div></div><div><h3>Results</h3><div>The proposed model outlines four interconnected domains of pharmaceutical intervention: (1) integration of pharmacists into formal health education settings, (2) systematic assessment and support of patients' Health Literacy during pharmacy encounters, (3) outreach to vulnerable populations excluded from formal education systems, and (4) alignment of medication information with users’ actual Health Literacy levels to support rational medication use.</div></div><div><h3>Conclusions</h3><div>This proposed model underscores the transformative potential of pharmacy practice by expanding pharmacists’ roles as health educators and intersectoral communicators. By repositioning pharmacists as connectors between educational and healthcare systems, it offers a strategic framework to address systemic Health Literacy barriers and promote appropriate and informed medication use.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"21 12","pages":"Pages 1096-1105"},"PeriodicalIF":2.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144862480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital educational interventions for antimicrobial stewardship: A systematic review","authors":"Michela Monaci ,&nbsp;Antonia Rake ,&nbsp;Marta Acampora ,&nbsp;Serena Barello","doi":"10.1016/j.sapharm.2025.07.003","DOIUrl":"10.1016/j.sapharm.2025.07.003","url":null,"abstract":"<div><h3>Background</h3><div>Antimicrobial Stewardship programs (ASPs) help reduce antimicrobial resistance (AMR) by promoting responsible antibiotic use. However, implementation is often inconsistent, especially in low-resource settings. Digital health technologies (DHTs) provide scalable and flexible means to enhance ASPs, particularly through targeted educational interventions for clinicians, students, and the public.</div></div><div><h3>Aim</h3><div>This systematic review aimed to evaluate the effectiveness of digital educational within ASPs by enhancing knowledge and driving behavior change, with a specific focus on the educational strategies employed, their theoretical underpinnings, and their differential impact across populations and settings.</div></div><div><h3>Method</h3><div>This review followed PRISMA and Joanna Briggs Institute (JBI) guidelines, with a protocol registered in PROSPERO. A comprehensive search of four databases (PubMed, Web of Science, Scopus, and CINAHL) was conducted to identify primary peer-reviewed studies published in English that quantitatively evaluated digital educational ASPs. Risk of bias was assessed using standardized appraisal tools.</div></div><div><h3>Results</h3><div>Twenty-three studies, conducted in diverse contexts and targeting different stakeholders, were included in the review. All interventions reported positive impacts on knowledge enhancement and behavior change. Engagement-driven approaches, such as interactive modules, real-time feedback, and case-based simulations, were most common, and strategies were tailored to the specific target groups. However, theoretical underpinnings were rarely reported, with only two studies explicitly grounded in behavior change theory. Few studies included long-term follow-up assessments, and most lacked rigorous designs such as randomization. Risk of bias was assessed and varied across studies. The interventions varied widely in duration, frequency, and delivery format, limiting comparability.</div></div><div><h3>Conclusion</h3><div>Digital educational ASPs show strong promise in improving knowledge and driving behavior change across a wide range of settings and stakeholder groups. Their adaptability, scalability, and user-centered design underscore their potential as valuable tools in the global effort to combat antimicrobial resistance. To maximize their long-term impact, future interventions should be informed by behavioral theory, include follow-up beyond six months, and address contextual needs in low-resource settings.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"21 12","pages":"Pages 991-1012"},"PeriodicalIF":2.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New program theory in pharmacist-led patient-centered medication review in general practice: A qualitative pilot study","authors":"Susanne Kaae ,&nbsp;Sara Sommer Holst ,&nbsp;Johanne Mølby Hansen ,&nbsp;Charlotte Vermehren","doi":"10.1016/j.sapharm.2025.07.002","DOIUrl":"10.1016/j.sapharm.2025.07.002","url":null,"abstract":"<div><h3>Background</h3><div>Pharmacists are increasingly engaged in general practice to contribute to rational prescribing and to reduce the workloads. To further improve patients' outcomes, a new <em>patient-centered</em> medication review (MR) model in primary care for polypharmacy patients was developed. This model involves patients in an initial ‘problem detection meeting’ with the pharmacist and in a meeting with the pharmacist and the General Practitioner (GP) to discuss MR findings.</div></div><div><h3>Objectives</h3><div>To pilot test the new MR model to supplement existing program theory.</div></div><div><h3>Methods</h3><div>Qualitative descriptive nonparticipatory observations of the MR model were carried out in two general practices in Denmark to identify Context elements and determine how the Intervention was enacted. Semistructured interviews with GPs, patients and the pharmacist were conducted to establish Outcomes. Through principles of realist evaluation, Mechanisms, i.e., links connecting Context, Intervention and Outcomes, were inferred.</div></div><div><h3>Results</h3><div>The new model led to satisfaction among patients and GPs. Three central mechanisms were: 1) alignment between the pharmacist and the GP in their understanding of MR work; 2) investment in relational work; and 3) flexibility, allowing the model to fulfill the needs of GPs despite differences in experiences with polypharmacy, working styles, and knowledge of enrolled patients.</div></div><div><h3>Conclusion</h3><div>The new model illustrates how pharmacists can support GPs. New program theory regards the importance of compatible perspectives between pharmacists and GPs on appropriate polypharmacy work, i.e., ‘shared mental models’, the ways GPs can develop their mental models when interacting with pharmacists, and the usefulness of relational work when the models clash.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"21 12","pages":"Pages 1070-1078"},"PeriodicalIF":2.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144761806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of medication therapy management on medication adherence and health-related quality of life among non-dialysis chronic kidney disease patients","authors":"Shivaprasad Sirimalla ,&nbsp;Uday Venkat Mateti ,&nbsp;Pradeep Shenoy ,&nbsp;C.S. Shastry ,&nbsp;Shraddha Shetty","doi":"10.1016/j.sapharm.2025.08.002","DOIUrl":"10.1016/j.sapharm.2025.08.002","url":null,"abstract":"<div><h3>Background</h3><div>Chronic kidney disease (CKD) is a progressive disease, often associated with poor medication adherence and reduced health related quality of life (HRQoL). Medication therapy management (MTM) is a range of services provided to patients and has been shown to enhance medication adherence and HRQoL, yet its impact on non-dialysis CKD patients remains underexplored. So, the study was aimed to see the impact of MTM on medication adherence and HRQoL among non-dialysis CKD patients.</div></div><div><h3>Methodology</h3><div>The prospective, open-labelled randomization-controlled study was conducted among CKD non-dialysis patients. HRQoL was assessed using KDQoL-36 questionnaire. Medication adherence was assessed using the medication adherence scale. Both were assessed at baseline; 6^th and 12^th month follow up. MTM group received clinical pharmacist's MTM services along with usual care (UC). UC group received the hospital team's general care from the Doctors, Nurses, and other health care professionals.</div></div><div><h3>Results</h3><div>A total of 220 CKD patients has been enrolled into the both groups in 1:1 ratio. At baseline, most of the patients were having medium adherence in both MTM 82 (74.54) and UC 77 (70) groups, followed by low adherence with p value 0.131. At 6^th and 12^th month follow-up. Medication adherence was increased in the MTM group compared to the UC group with p value &lt;0.001. In the baseline, the more HRQoL score was found in the domain \"symptoms and problems list\" in both MTM 70.4 and UC groups 71.5 with the p value &gt;0.05. The HRQoL scores of 5 domains were significantly increased at the 6th month and 12th month in the MTM group compared to the UC group with p value &lt;0.05.</div></div><div><h3>Conclusion</h3><div>Study concluded, MTM services increased the medication adherence and HR-QoL of CKD non dialysis patients in MTM group compared to UC group. In future, MTM services can be implemented in healthcare settings.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"21 12","pages":"Pages 1090-1095"},"PeriodicalIF":2.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144849402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}