{"title":"Impact of medication therapy management on medication adherence and health-related quality of life among non-dialysis chronic kidney disease patients","authors":"Shivaprasad Sirimalla , Uday Venkat Mateti , Pradeep Shenoy , C.S. Shastry , Shraddha Shetty","doi":"10.1016/j.sapharm.2025.08.002","DOIUrl":"10.1016/j.sapharm.2025.08.002","url":null,"abstract":"<div><h3>Background</h3><div>Chronic kidney disease (CKD) is a progressive disease, often associated with poor medication adherence and reduced health related quality of life (HRQoL). Medication therapy management (MTM) is a range of services provided to patients and has been shown to enhance medication adherence and HRQoL, yet its impact on non-dialysis CKD patients remains underexplored. So, the study was aimed to see the impact of MTM on medication adherence and HRQoL among non-dialysis CKD patients.</div></div><div><h3>Methodology</h3><div>The prospective, open-labelled randomization-controlled study was conducted among CKD non-dialysis patients. HRQoL was assessed using KDQoL-36 questionnaire. Medication adherence was assessed using the medication adherence scale. Both were assessed at baseline; 6<sup>th</sup> and 12<sup>th</sup> month follow up. MTM group received clinical pharmacist's MTM services along with usual care (UC). UC group received the hospital team's general care from the Doctors, Nurses, and other health care professionals.</div></div><div><h3>Results</h3><div>A total of 220 CKD patients has been enrolled into the both groups in 1:1 ratio. At baseline, most of the patients were having medium adherence in both MTM 82 (74.54) and UC 77 (70) groups, followed by low adherence with p value 0.131. At 6<sup>th</sup> and 12<sup>th</sup> month follow-up. Medication adherence was increased in the MTM group compared to the UC group with p value <0.001. In the baseline, the more HRQoL score was found in the domain \"symptoms and problems list\" in both MTM 70.4 and UC groups 71.5 with the p value >0.05. The HRQoL scores of 5 domains were significantly increased at the 6th month and 12th month in the MTM group compared to the UC group with p value <0.05.</div></div><div><h3>Conclusion</h3><div>Study concluded, MTM services increased the medication adherence and HR-QoL of CKD non dialysis patients in MTM group compared to UC group. In future, MTM services can be implemented in healthcare settings.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"21 12","pages":"Pages 1090-1095"},"PeriodicalIF":2.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144849402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chloe Maxwell-Smith , Hayley Breare , Alejandro Dominguez Garcia , Tin Fei Sim , Krysten Blackford , Barbara A. Mullan
{"title":"Pharmacists’ barriers and enablers to delivering health behaviour recommendations for patients with behavioural determinants of disease: Application of the COM-B model","authors":"Chloe Maxwell-Smith , Hayley Breare , Alejandro Dominguez Garcia , Tin Fei Sim , Krysten Blackford , Barbara A. Mullan","doi":"10.1016/j.sapharm.2025.07.004","DOIUrl":"10.1016/j.sapharm.2025.07.004","url":null,"abstract":"<div><h3>Background</h3><div>Pharmacists are among the most trusted and accessible health professionals in Australia. Community pharmacists are well positioned to deliver brief health recommendations to reduce risk factors of communicable and non-communicable disease during patient interactions. However, effective facilitation of these interactions in pharmacy practice should be considered. The Capability, Opportunity, Motivation and Behaviour (COM-B) model provides a framework to map understanding of the factors affecting pharmacists’ delivery of health behaviour recommendations to patients, with the aim of reducing disease risk factors.</div></div><div><h3>Methods</h3><div>Thirteen semi-structured interviews were conducted with Australian community pharmacists (<em>M</em><sub><em>age</em></sub> = 38.7 years, <em>SD</em> = 15.6). Participants described their barriers and enablers to delivering brief health behaviour change recommendations during patient counselling. Transcripts were analysed using reflexive thematic analysis, with the COM-B model as a guiding framework.</div></div><div><h3>Results</h3><div>Three themes were identified: ‘<em>Perceptions of patient willingness’, ‘Professional Role and Identity’,</em> and <em>‘Structural constraints in pharmacy practice</em>.<em>’</em> Pharmacists reported being motivated to engage with patients about behaviour change but felt inhibited by retail-models of pharmacy, time constraints, and lack of experiential learning. A patient-centred pharmacy model, theoretical knowledge of behaviour change, proprietor support, and patient interest appeared to be instrumental in the effective facilitation of behaviour change advice.</div></div><div><h3>Discussion</h3><div>Pharmacists are reportedly motivated to engage with patients about health risk factors and disease management. However, external barriers to recommendations and lack of time may only be reduced with management support. Findings necessitate pharmacy model-level initiatives to effectively overcome barriers, such as educating pharmacists about the benefits of behavioural medicine, and training in brief behaviour change techniques through professional development opportunities. Behavioural medicine can enhance pharmacists’ capacity to support individuals in managing chronic and communicable disease, but this may need to be incorporated and prioritised early in pharmacy training, including throughout tertiary pharmacy curricula.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"21 12","pages":"Pages 1079-1089"},"PeriodicalIF":2.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mentorship in entry-to-practice pharmacy programs: A scoping review","authors":"Emelith Cerbito , Abrar Abdelrahman , Safa Tahar, Baleegh Abdulmajeed, Alla El-Awaisi","doi":"10.1016/j.sapharm.2025.07.006","DOIUrl":"10.1016/j.sapharm.2025.07.006","url":null,"abstract":"<div><h3>Background</h3><div>Mentorship is a well-established educational strategy with demonstrated benefits across health professions education, including pharmacy. However, there remains paucity with regards to understanding mentorship in entry-to-practice pharmacy programs. This scoping review aims to identify and describe mentorship models used in mentoring pharmacy students in entry-level pharmacy, outcomes, characteristics of an effective mentorship, and gaps in current literature on mentorship in pharmacy.</div></div><div><h3>Methods</h3><div>A systematic literature search was initially conducted in early 2022 across PubMed, Embase, EBSCO, and Scopus, using a combination of keywords and MeSH terms related to mentorship in entry-level pharmacy education. The search was updated in May 2025 to include studies published between 2022 and 2024. Two independent reviewers screened all titles, abstracts, and full texts. Data were extracted on study characteristics and outcome's, and findings were synthesized using Hamlin and Sage's conceptual framework for effective mentoring.</div></div><div><h3>Results</h3><div>Out of the 1726 identified records, 25 studies met the inclusion criteria. Most were conducted in the United States (80 %, n = 20). Most studies aimed to assess the impact of mentorship on mentees' attitude and development. Several studies incorporated traditional mentoring (n = 8), group mentoring (n = 5), hybrid mentoring (n = 7), and peer mentoring (n = 3). Five recurring elements were found to support effective mentorship in pharmacy programs robust recruitment process and training, clear goals, effective communication, mentor-mentee matching, and regular feedback/evaluation.</div></div><div><h3>Conclusion</h3><div>Mentorship is a valuable component of pharmacy education, with demonstrated benefits for both mentees and mentors. The findings highlight the need for structured mentorship frameworks, standardized evaluation tools, and greater global representation in future research. Implementing evidence-informed mentorship programs may support student success and contribute to the advancement of the pharmacy profession.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"21 12","pages":"Pages 1024-1041"},"PeriodicalIF":2.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144761805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aimee Denver-Wason, Emma Dunlop, Natalie Weir, Marion Bennie
{"title":"Prioritising tool(s) for measuring chronic pain-related outcomes as part of the pharmacotherapy service in Scotland: a patient consensus study","authors":"Aimee Denver-Wason, Emma Dunlop, Natalie Weir, Marion Bennie","doi":"10.1016/j.sapharm.2025.06.004","DOIUrl":"10.1016/j.sapharm.2025.06.004","url":null,"abstract":"<div><h3>Background</h3><div>Pharmacist-led pharmacotherapy services in Scotland play a crucial role in managing people's chronic pain. Exploring patient preferences regarding pain-specific and quality of life assessment tools is essential for delivering patient-centred care. However, the current evidence base remains limited.</div></div><div><h3>Objectives</h3><div>To obtain patient consensus on their preferred tools appropriate for measuring chronic pain outcomes as part of the pharmacist-led pharmacotherapy service in Scotland; and to obtain patient perspectives on the interpretability, comprehensibility and accessibility of tool(s).</div></div><div><h3>Methods</h3><div>A predominantly convenience sampling strategy recruited patients with experience of chronic pain in Scotland. An online modified nominal group technique (NGT) was conducted. This involved reviewing five outcomes tools, round robin feedback, discussions, ranking, and a final consensus exercise. Ranking results were used to identify the most preferable tool for use in practice. Discussions throughout the NGT were thematically analysed to explore the comprehensibility, interpretability, and accessibility of the tools.</div></div><div><h3>Result</h3><div>Seven patients participated, from 6 of 14 Scottish health boards. Consensus identified the Brief Pain Inventory as the most preferable tool, with the EQ-5D-5L and Short-Form McGill Pain Questionnaire ranked joint second. Thematic analysis highlighted key areas for consideration related to tool comprehensibility and fundamental concepts surrounding the definition of pain and the subjectivity of the language used in tools. General comments included the importance of digital accessibility, and preferences around pain-specific vs HRQoL tools.</div></div><div><h3>Conclusions</h3><div>The findings will facilitate decision making regarding the delivery of pharmacotherapy chronic pain services in Scotland. There is a preference for a disease-specific tool, however a combination of the BPI and the more general EQ-5D-5L could be used to capture more insight into the impact of the service on patients. Future work should test these tools in diverse populations and explore the use of the EQ-5D-5L with condition-specific tools for patients with various chronic conditions.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"21 12","pages":"Pages 1050-1058"},"PeriodicalIF":2.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Adherence and persistence to heart failure guideline-directed medical therapy: A systematic review of studies based on electronic healthcare data","authors":"Nerea Báez-Gutiérrez , Cristina Galindo-García , Héctor Rodríguez-Ramallo , Susana Sánchez-Fidalgo","doi":"10.1016/j.sapharm.2025.07.005","DOIUrl":"10.1016/j.sapharm.2025.07.005","url":null,"abstract":"<div><h3>Background</h3><div>Heart failure (HF) significantly impacts global morbidity, mortality, and healthcare costs. Effective treatment involves multiple guideline-directed medical therapies, such as beta-blockers, angiotensin-converting enzyme inhibitors, and mineralocorticoid receptor antagonists, angiotensin receptor–neprilysin inhibitor and sodium-glucose cotransporter 2 inhibitors. However, medication adherence and persistence in HF patients are often suboptimal, negatively influencing clinical outcomes. This systematic review assesses medication adherence and persistence among HF patients and their relationship to clinical outcomes.</div></div><div><h3>Methods</h3><div>A systematic review following PRISMA guidelines was conducted, evaluating observational studies utilizing electronic healthcare databases published between 1990 and 2024. Studies reporting adherence or persistence to HF pharmacological treatments, measured by pharmacy claims or electronic health records, were included. Primary adherence (initial dispensing), secondary adherence (continued refilling), and persistence (duration until medication discontinuation) were analyzed.</div></div><div><h3>Results</h3><div>Fifty-two studies involving 2,001,178 HF patients were reviewed. No studies adequately assessed primary adherence. Secondary adherence was predominantly evaluated using Proportion of Days Covered or Medication Possession Ratio, with adherence generally below optimal levels (<80 %). Medication adherence declined significantly with increased regimen complexity and over extended periods. Persistence rates were notably lower in long-term follow-ups, especially with mineralocorticoid receptor antagonists. Higher medication adherence and persistence consistently correlated with reduced hospitalizations, emergency department visits, and mortality rates. Methodological heterogeneity across studies precluded the feasibility of a meta-analysis.</div></div><div><h3>Conclusions</h3><div>Medication adherence and persistence among HF patients remain suboptimal, particularly with complex, multi-drug regimens and prolonged treatments. Improved adherence was correlated with better clinical outcomes, underscoring the need for standardized adherence measures and targeted interventions to enhance patient outcomes.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"21 12","pages":"Pages 1013-1023"},"PeriodicalIF":2.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144683410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Health Belief Profiles and Nonadherence to Oral Anticancer Medication in Cancer Survivors: A Latent Profile Analysis","authors":"Meng-Jung Wen , Olayinka Shiyanbola","doi":"10.1016/j.sapharm.2025.03.020","DOIUrl":"10.1016/j.sapharm.2025.03.020","url":null,"abstract":"","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"21 11","pages":"Page e29"},"PeriodicalIF":2.8,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144925637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Counseling in Bulgarian pharmacies –Expectation vs Perception","authors":"Hristina Lebanova , Svetoslav Stoev , Elitsa Lalkova","doi":"10.1016/j.sapharm.2025.02.073","DOIUrl":"10.1016/j.sapharm.2025.02.073","url":null,"abstract":"","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"21 11","pages":"Page e24"},"PeriodicalIF":2.8,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144926155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luana Mifsud Buhagiar , Lara Giudice , Maria Mamo , Amar Abbas , Audrey Magri , Anthony Serracino Inglott
{"title":"Strengthening multidisciplinary approaches against antimicrobial resistance: A collaborative initiative reflecting on science, policy, regulatory and clinical practices","authors":"Luana Mifsud Buhagiar , Lara Giudice , Maria Mamo , Amar Abbas , Audrey Magri , Anthony Serracino Inglott","doi":"10.1016/j.sapharm.2025.02.035","DOIUrl":"10.1016/j.sapharm.2025.02.035","url":null,"abstract":"","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"21 11","pages":"Page e10"},"PeriodicalIF":2.8,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144926681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}