Učenye zapiski učreždeniâ obrazovaniâ "Vitebskaâ orderna "Znak početa" gosudarstvennaâ akademiâ veterinarnoj mediciny"最新文献_第3页

USE OF IMMUNOTROPIC DRUGS IN REALIZATION OF REPRODUCTIVE POTENTIAL ОF YOUNG STOCK PIGS 利用免疫药物实现繁殖潜力Оf幼猪

Učenye zapiski učreždeniâ obrazovaniâ "Vitebskaâ orderna "Znak početa" gosudarstvennaâ akademiâ veterinarnoj mediciny" Pub Date : 2023-01-01 DOI: 10.52368/2078-0109-2023-59-1-103-106

V.G. Tyurin, N.V. Rodionova, V.G. Semenov, D.A. Nikitin, L.P. Gladkikh, A.V. Kovalenko, Е.А. Kapitonova

{"title":"USE OF IMMUNOTROPIC DRUGS IN REALIZATION OF REPRODUCTIVE POTENTIAL ОF YOUNG STOCK PIGS","authors":"V.G. Tyurin, N.V. Rodionova, V.G. Semenov, D.A. Nikitin, L.P. Gladkikh, A.V. Kovalenko, Е.А. Kapitonova","doi":"10.52368/2078-0109-2023-59-1-103-106","DOIUrl":"https://doi.org/10.52368/2078-0109-2023-59-1-103-106","url":null,"abstract":"In the conditions of modern pig farming, the animal body experiences a high physiological load. Animals are constantly affected by various stress factors due to the peculiarities of the technology of maintenance. Since it is impossible to fully exclude the effect of stress factors, an important role in minimizing negative consequences is played by optimizing the conditions of housing, as well as increasing the resistance and ability of the animal organism to adapt. The purpose of this work is to realize the biopotential of the reproductive qualities of replacement pigs by the immune correction of the animal body with PigStim-V and PigStim-F preparations. For the experiment, 30 suckling pigs (females) were formed into 3 groups of 10 animals each. The pigs of the 1st experimental group were injected intramuscularly the immunotropic preparation PigStim-V at a dose of 1 ml per head three times, on the 15th, 20th and 25th days of life. Pigs of the 2nd experimental group were injected the immunotropic preparation PigStim-F by the similar scheme. No immunotropic drugs were injected to pigs of the control group. Insemination of pigs was carried out in the 4th estrus, at the age of 7.5-8 months and at the optimal live weight. A positive effect of the immunotropic preparations PigStim-V and PigStim-F on the reproductive qualities of replacement pigs was revealed. In the experimental groups, an earlier start of estrus, a decrease in the age of the first insemination, and an increase in its effectiveness have been noticed. Against the background of immune correction, the rate of prolificacy increased, the stillbirth rate, and the index of incidence of postpartum diseases (MMA) decreased, the safety and growth rate increased; in sows, the period from weaning to the onset of the heat reduced.","PeriodicalId":477320,"journal":{"name":"Učenye zapiski učreždeniâ obrazovaniâ \"Vitebskaâ orderna \"Znak početa\" gosudarstvennaâ akademiâ veterinarnoj mediciny\"","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135698874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

EFFECT OF THERAPEUTIC AND PREVENTIVE MEASURES IN THE DRY PERIOD ON THE EFFICIENCY OF ANTIBIOTIC THERAPY FOR MASTITIS IN LACTATING COWS 干期治疗和预防措施对哺乳期奶牛乳腺炎抗生素治疗效果的影响

Učenye zapiski učreždeniâ obrazovaniâ "Vitebskaâ orderna "Znak početa" gosudarstvennaâ akademiâ veterinarnoj mediciny" Pub Date : 2023-01-01 DOI: 10.52368/2078-0109-2023-59-2-22-24

M.S. Zhukov, A.V. Galkin

{"title":"EFFECT OF THERAPEUTIC AND PREVENTIVE MEASURES IN THE DRY PERIOD ON THE EFFICIENCY OF ANTIBIOTIC THERAPY FOR MASTITIS IN LACTATING COWS","authors":"M.S. Zhukov, A.V. Galkin","doi":"10.52368/2078-0109-2023-59-2-22-24","DOIUrl":"https://doi.org/10.52368/2078-0109-2023-59-2-22-24","url":null,"abstract":"A comparative study of the effect of preventive antibiotic treatment on the treatment efficiency of bovine mastitis was carried out. The experiment was carried out on lactating Holstein cows of 3-5 lactation with diagnosed subclinical mastitis. The cows were divided into 3 groups: Group 1 (n=13) – cows with no previous cases of mastitis and with no antibiotics given to prevent mastitis during the dry period; Group 2 (n=15) – cows with no previous cases of mastitis, which were injected azithromycin as preventive measures, and received a drug based on cefapirin intercisternally, within the drying off period; and Group 3 (n=11) – cows, that had previously undergone mastitis treatment (2-3 times). The animals from groups 1 and 2 were injected azithromycin and received a drug based on cefapirin intercisternally, within the drying off period, as well as cephalosporins of the 3rd generation injected during the postpartum period. It was found that the treatment efficacy of cows from group 1 was 84.6%, and in groups 2 and 3 was lower by 37.9 and 48.2%, respectively. Spearman's correlation analysis has shown that there is a significant inverse correlation between the presence of preventive antibiotic treatment and the efficacy of mastitis treatment (r = - 0.40; p = 0.011), indicating that preventive antibiotic treatment reduces the subsequent treatment efficacy of mastitis.","PeriodicalId":477320,"journal":{"name":"Učenye zapiski učreždeniâ obrazovaniâ \"Vitebskaâ orderna \"Znak početa\" gosudarstvennaâ akademiâ veterinarnoj mediciny\"","volume":"28 6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135699405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ANTIGENIC AND GENETIC COMPOSITION OF BOVINE RESPIRATORY SYNCYTIAL VIRUS 牛呼吸道合胞病毒的抗原和基因组成

Učenye zapiski učreždeniâ obrazovaniâ "Vitebskaâ orderna "Znak početa" gosudarstvennaâ akademiâ veterinarnoj mediciny" Pub Date : 2023-01-01 DOI: 10.52368/2078-0109-2023-59-1-92-95

P.P. Krasochka, K.V. Kalesnikovich

引用次数: 0

ANALYSIS OF HELMINTHIC INFESTATION IN ALIEN FISH SPECIES OF THE GOBIIDAE FAMILY FROM THE TERRITORY OF PSRER 中华人民共和国境内虾蛄科外来鱼类寄生虫侵染情况分析

Učenye zapiski učreždeniâ obrazovaniâ "Vitebskaâ orderna "Znak početa" gosudarstvennaâ akademiâ veterinarnoj mediciny" Pub Date : 2023-01-01 DOI: 10.52368/2078-0109-2023-59-2-41-46

N.G. Nadina, L.N. Akimova

引用次数: 0

MORPHOLOGICAL AND BIOCHEMICAL PARAMETERS OF BLOOD IN DRY COWS WHITH MEGASHANS-I AND MEGASHANS-II FEED ADDITIVES USED IN THEIR DIETS 饲粮中添加megashans - 1和megashans-ii饲料添加剂对干牛血液形态和生化参数的影响

Učenye zapiski učreždeniâ obrazovaniâ "Vitebskaâ orderna "Znak početa" gosudarstvennaâ akademiâ veterinarnoj mediciny" Pub Date : 2023-01-01 DOI: 10.52368/2078-0109-2023-59-2-103-107

M.M. Karpenia, V.V. Guyvan

引用次数: 0

PATHOMORPHOLOGICAL CHANGES IN FIRST-CALF HEIFERS IN CASE OF ASSOCIATIVE COURSE OF THE DISEASE CAUSED BY HEMOLYTIC STRAIN OF E. COLI AND BOVINE HERPES VIRUS 1 由大肠杆菌溶血株和牛疱疹病毒1引起的联合病程中初生牛犊的病理形态学变化

Učenye zapiski učreždeniâ obrazovaniâ "Vitebskaâ orderna "Znak početa" gosudarstvennaâ akademiâ veterinarnoj mediciny" Pub Date : 2023-01-01 DOI: 10.52368/2078-0109-2023-59-2-30-37

A.A. Mironova, L.P. Mironova, T.Sh. Khamidullin, N.G. Sidorenko, O.B. Pavlenko, O.A. Manzhurina

引用次数: 0

ECONOMIC AND PREVENTIVE EFFICIENCY OF INACTIVATED EMULSIFIED VACCINE FOR POULTRY SALMONELLOSIS PREVENTION 预防家禽沙门氏菌病灭活乳化苗的经济性和预防效果

Učenye zapiski učreždeniâ obrazovaniâ "Vitebskaâ orderna "Znak početa" gosudarstvennaâ akademiâ veterinarnoj mediciny" Pub Date : 2023-01-01 DOI: 10.52368/2078-0109-2023-59-2-18-22

I.A. Darouskikh

引用次数: 0

PHYSIOLOGICAL FEATURES OF NATIVE AND CANNED SPERM OF CATS WITH DIFFERENT ANTIGENIC PROFILE OF ERYTHROCYTES 不同红细胞抗原谱猫精子的生理特性

Učenye zapiski učreždeniâ obrazovaniâ "Vitebskaâ orderna "Znak početa" gosudarstvennaâ akademiâ veterinarnoj mediciny" Pub Date : 2023-01-01 DOI: 10.52368/2078-0109-2023-59-2-50-54

A.V. Petryaeva, Yu.A. Vatnikov, A.V. Tkachev, O.L. Tkacheva

{"title":"PHYSIOLOGICAL FEATURES OF NATIVE AND CANNED SPERM OF CATS WITH DIFFERENT ANTIGENIC PROFILE OF ERYTHROCYTES","authors":"A.V. Petryaeva, Yu.A. Vatnikov, A.V. Tkachev, O.L. Tkacheva","doi":"10.52368/2078-0109-2023-59-2-50-54","DOIUrl":"https://doi.org/10.52368/2078-0109-2023-59-2-50-54","url":null,"abstract":"The presence of antisperm antibodies in the blood and secretions of the genital tract can inhibit the interaction of spermatozoa with eggs, and they can inhibit the development of zygotes after fertilization. Therefore, the identification and study of antigens that can reduce reproductive function is of great importance for understanding their relationship with infertility and with antisperm antibodies. The physiological features of native and frozen-thawed sperm of cats with different antigenic profile of erythrocytes by blood groups were established. The mobility of native spermatozoa was the lowest in cats of blood group AB, which is 6.45% less (P<0.001) than the mobility of spermatozoa in animals with blood group A and 6.73% less (P<0.001) than the activity of spermatozoa in cats with the blood group blood B. The concentration in all ejaculates was from 78 to 425 million / ml. The highest sperm concentration was in cats with blood type AB, which is 0.64 million/ml more than in blood group B and 32.57 million/ml more (P<0.01) in cats with blood type A. The largest number of pathological forms of spermatozoa were found by us in cats with blood type AB, which is 4.34% more (P<0.05) from blood group A and 5.15% more (P<0.05) from cats with blood type B. The data obtained allow us to conclude that for the creation of cryobanks of sperm production, cats with blood type A or B are most desirable. blood group B and 5.55% more (P<0.01) from animals with blood group AB. The data obtained allow us to state that the physiological usefulness of germ cells of cats of Russian selection is better in cats with blood type A or B. hours more (P<0.05) from blood group B and 0.68 hours more (P<0.001) from animals of blood group AB.","PeriodicalId":477320,"journal":{"name":"Učenye zapiski učreždeniâ obrazovaniâ \"Vitebskaâ orderna \"Znak početa\" gosudarstvennaâ akademiâ veterinarnoj mediciny\"","volume":"91 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135748968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

EXPRESSION LEVEL OF GENES OF PRO- AND ANTI-INFLAMMATORY CYTOKINES IN THE BLOOD OF COWS WITH OVARIAN HYPOFUNCTION AND THE USE OF DRUG BASED ON GM-CSF 促炎性和抗炎性细胞因子基因在卵巢功能低下奶牛血液中的表达水平及gm-csf药物的应用

Učenye zapiski učreždeniâ obrazovaniâ "Vitebskaâ orderna "Znak početa" gosudarstvennaâ akademiâ veterinarnoj mediciny" Pub Date : 2023-01-01 DOI: 10.52368/2078-0109-2023-59-2-55-60

E.M. Stepanov, V.I. Mikhalev, N.V. Pasko

{"title":"EXPRESSION LEVEL OF GENES OF PRO- AND ANTI-INFLAMMATORY CYTOKINES IN THE BLOOD OF COWS WITH OVARIAN HYPOFUNCTION AND THE USE OF DRUG BASED ON GM-CSF","authors":"E.M. Stepanov, V.I. Mikhalev, N.V. Pasko","doi":"10.52368/2078-0109-2023-59-2-55-60","DOIUrl":"https://doi.org/10.52368/2078-0109-2023-59-2-55-60","url":null,"abstract":"The article presents the material for studying the expression level of pro- and anti-inflammatory cytokine genes in the blood of cows with ovarian hypofunction and the use of the drug based on gm-csf (granulocyte-macrophage colony-stimulating factor). It has been established that disorders in the functional activity of the genital gonads in cows occur against the background of an increase in the relative expression level of genes of pro-inflammatory cytokines (IL-1β - by 1.56 and 2.11 times, IL-2 - by 1.41 and 2.29 times, TNFα - by 19.5 and 48.8%), while reducing anti-inflammatory ones (IL-4 - by 27.6 and 37.9%, IL-10 - by 8.3 and 36.1%). An imbalance between the expression level of pro- and anti-inflammatory cytokines in the blood of cows is one of the etiological factors leading to hormonal imbalance and the development of hypofunctional ovarian disorders. The administration of a drug based on gm-csf to cows during insemination once at a dose of 5.0 ml to normalize the functional activity of the ovaries in case of their hypofunctional state with anovulation phenomena contributed to a decrease in the expression level of IL-1β by 27.3%, IL-2 – by 16.7%, TNFα – by 8.2%, with an increase in the expression of IL-4 by 4.8%, IL-10 – by 6.1%, which ensured a clinical efficacy of 86.7%. The use of a drug based on gm-csf in the cows with ovarian hypofunction, manifested by anaphrodisia, twice with an interval of 7 days at a dose of 10.0 ml provided a decrease in the expression level of IL-1β - by 1.9 times, IL-2 – by 38.5%, TNFα – by 14.8%, with an increase in IL-4 - by 11.1%, IL-10 – by 39.1% and a clinical efficacy of 90.0%.","PeriodicalId":477320,"journal":{"name":"Učenye zapiski učreždeniâ obrazovaniâ \"Vitebskaâ orderna \"Znak početa\" gosudarstvennaâ akademiâ veterinarnoj mediciny\"","volume":"152 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135800264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0