Cardiovascular Revascularization Medicine最新文献

{"title":"Long-term outcomes of unselected patients undergoing coronary angiography according to the presence or absence of type II diabetes mellitus","authors":"Philipp Steinke ,&nbsp;Tobias Schupp ,&nbsp;Lasse Kuhn ,&nbsp;Mohammad Abumayyaleh ,&nbsp;Mohamed Ayoub ,&nbsp;Kambis Mashayekhi ,&nbsp;Thomas Bertsch ,&nbsp;Niklas Ayasse ,&nbsp;Mahboubeh Jannesari ,&nbsp;Fabian Siegel ,&nbsp;Daniel Dürschmied ,&nbsp;Michael Behnes ,&nbsp;Ibrahim Akin","doi":"10.1016/j.carrev.2024.12.001","DOIUrl":"10.1016/j.carrev.2024.12.001","url":null,"abstract":"<div><h3>Objective</h3><div>The study investigates long-term outcomes of unselected inpatients undergoing invasive coronary angiography (CA) with and without diabetes mellitus type II (T2DM).</div></div><div><h3>Background</h3><div>Due to continual shifts in demographics and advancements in treating cardiovascular disease, there has been a notable evolution in the types of patients undergoing CA over the past decades. Comprehensive data on the extended outcomes of CA patients, both with and without concurrent T2DM, remains scarce.</div></div><div><h3>Methods</h3><div>Consecutive inpatients undergoing invasive CA from 2016 to 2022 were included at one institution. The prognosis of T2DM in patients undergoing CA was investigated with regard to the risk rehospitalization for heart failure (HF), acute myocardial infarction (AMI) and coronary revascularization at 36 months of follow-up. Statistical analyses included Kaplan-Meier uni- and multivariable Cox proportional regression analyses.</div></div><div><h3>Results</h3><div>From 2016 to 2022, 7150 patients undergoing CA were included with a prevalence of T2DM of 31.2 %. Compared to non-diabetics, patients with T2DM had a higher prevalence (78.0 % vs. 64.3 %; <em>p</em> = 0.001) and extent (3-vessel disease: 36.9 % vs. 23.8 %; <em>p</em> = 0.001) of coronary artery disease (CAD). At 36 months, patients with T2DM had a higher risk rehospitalization for worsening HF (29.0 % vs. 18.2 %; <em>p</em> = 0.001), AMI (9.9 % vs. 6.6 %; p = 0.001), alongside with a higher need for coronary revascularization (10.7 % vs. 7.2 %; <em>p</em> = 0.001) compared to patients without. Even after multivariable adjustment, the risk of rehospitalization for HF (HR = 1.229; 95 % CI 1.099–1.374; <em>p</em> = 0.001), AMI (HR = 1.270; 95 % CI 1.052–1.534; <em>p</em> = 0.013) and coronary revascularization (HR = 1.457; 95 % CI 1.213–1.751; p = 0.001) was higher in patients with T2DM. Especially in patients with left ventricular ejection fraction (LVEF) ≥ 35 %, T2DM was associated with a higher risk of AMI- (HR = 1.395, 95 % CI: 1.104 – 1.763, p = 0.005) and PCI-related rehospitalization (HR = 1.442, 95 % CI: 1.185 – 1.775, p = 0.001).</div></div><div><h3>Conclusion</h3><div>In unselected patients undergoing CA, T2DM represents an independent predictor of HF-related rehospitalization, AMI- and for PCI- at 36 months.</div></div>","PeriodicalId":47657,"journal":{"name":"Cardiovascular Revascularization Medicine","volume":"78 ","pages":"Pages 73-79"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142882600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of pulmonary hypertension on short and long-term outcome after mitral transcatheter edge-to-edge repair: A meta-analysis","authors":"Sivaram Neppala ,&nbsp;Himaja Dutt Chigurupati ,&nbsp;Ayman Fath ,&nbsp;Gowthami Sai Kogilathota Jagirdhar ,&nbsp;Harigopal Sandhyavenu ,&nbsp;Jeffery Bolte ,&nbsp;Abdullah Naveed Muhammad ,&nbsp;Yasar Sattar ,&nbsp;Rupak Desai ,&nbsp;Ralph A. Defronzo ,&nbsp;Timir K. Paul ,&nbsp;Anand Prasad","doi":"10.1016/j.carrev.2024.12.012","DOIUrl":"10.1016/j.carrev.2024.12.012","url":null,"abstract":"<div><h3>Background</h3><div>Pulmonary hypertension (pHTN) has been associated with increased morbidity and mortality after mitral Transcatheter Edge-to-Edge Repair (TEER), but the association remains uncertain. This study aims to evaluate the impact of pHTN on cardiovascular outcomes following TEER.</div></div><div><h3>Methods</h3><div>We searched PubMed, Scopus, and Medline to identify studies reporting outcomes after TEER in individuals with pHTN. Utilizing a random-effects model, we ascertained a pooled odds ratio (OR) of clinical outcomes in patients with pulmonary artery systolic pressure (PASP &gt;50 mmHg) vs. without (PASP &lt;50 mmHg) severe pHTN.</div></div><div><h3>Results</h3><div>We included seven studies with 27,965 patients. The mean age was 79.9 (±5.2) years; 53 % were male, and 75 % were New York Heart Association (NYHA) class-III/IV with a median follow-up of 360 days. Patients with severe pHTN had higher odds of in-hospital all-cause mortality (OR: 1.99, 95 % CI: 1.69–2.34, <em>p</em> &lt; 0.00001) and Major adverse cardiovascular events (MACE) (OR: 1.38, 95 % CI: 1.22–1.56, p &lt; 0.00001) compared to patients without severe pHTN.</div></div><div><h3>Conclusions</h3><div>Severe pHTN is associated with increased risks of all-cause mortality, MACE, and higher heart failure rehospitalizations in patients undergoing mitral TEER. Prospective trials are necessary to validate the findings and determine if early intervention improves clinical outcomes.</div></div>","PeriodicalId":47657,"journal":{"name":"Cardiovascular Revascularization Medicine","volume":"78 ","pages":"Pages 88-96"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144676165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gender disparity in morbidity and mortality among patients with ST-elevation myocardial infarction due to spontaneous coronary artery dissection complicated by cardiogenic shock","authors":"Magdi Zordok ,&nbsp;Muhammad Etiwy ,&nbsp;Mohamed Abdelazeem ,&nbsp;Sourbha S. Dani ,&nbsp;Mariam Tawadros ,&nbsp;Hady T. Lichaa ,&nbsp;Jimmy L. Kerrigan ,&nbsp;Babar Basir ,&nbsp;Khaldoon Alaswad ,&nbsp;Michael Miedema ,&nbsp;Emmanouil S. Brilakis ,&nbsp;Michael Megaly","doi":"10.1016/j.carrev.2024.11.010","DOIUrl":"10.1016/j.carrev.2024.11.010","url":null,"abstract":"<div><h3>Background</h3><div>There is limited data on gender differences among patients with spontaneous coronary artery dissection<span> (SCAD) who present as ST-elevation myocardial infarction (STEMI) and develop cardiogenic shock (CS).</span></div></div><div><h3>Objectives</h3><div>To describe outcomes of SCAD patients presenting with STEMI and CS and outline the differences between men and women.</div></div><div><h3>Methods</h3><div>We queried the US Nationwide Readmissions Database (NRD) from January 2016 to December 2020 to identify patients with SCAD presenting with STEMI who developed CS. We compared the characteristics, trends, and outcomes between men and women in this cohort.</div></div><div><h3>Results</h3><div>Out of 582,633 hospitalizations with STEMI, 0.2 % (1176 patients) had SCAD, of which 346 (29.4 %) had CS. There was no difference in median age between men and women (64 years (IQR 57–71) vs. 63 years (IQR 49–72), <em>p</em> = 0.181). Men had a higher prevalence of prior myocardial infarction (MI) (14.2 % vs. 6.2 %, <em>p</em><span><span> = 0.021). The overall mortality rate of SCAD patients with AMI-CS was 28.2 %, with no difference between men and women. Patients with SCAD who had CS and underwent </span>CABG<span> had a mortality of 20.3 %. ECMO was used in 6.1 % of SCAD patients presenting with STEMI and CS, with a survival rate of 49.9 %.</span></span></div></div><div><h3>Conclusion</h3><div>There were no differences in the baseline characteristics, rates of revascularization, or in-hospital mortality between men and women who had SCAD complicated by CS (SCAD-CS). Patients with SCAD-CS patients who underwent CABG had around 80 % in-hospital survival. CABG should be considered as a method of revascularization in this patient cohort.</div></div>","PeriodicalId":47657,"journal":{"name":"Cardiovascular Revascularization Medicine","volume":"78 ","pages":"Pages 23-30"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142752014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Right ventricular-pulmonary arterial coupling in transcatheter structural heart interventions","authors":"Panagiotis Theofilis ,&nbsp;Panayotis K. Vlachakis ,&nbsp;Paschalis Karakasis ,&nbsp;Evangelos Oikonomou ,&nbsp;Athanasios Sakalidis ,&nbsp;Kyriakos Dimitriadis ,&nbsp;Konstantinos Tsioufis ,&nbsp;Dimitris Tousoulis","doi":"10.1016/j.carrev.2025.05.022","DOIUrl":"10.1016/j.carrev.2025.05.022","url":null,"abstract":"<div><div>Right ventricular–pulmonary arterial (RV–PA) coupling describes the interaction between right ventricular contractility<span><span> and pulmonary arterial afterload, offering a comprehensive assessment of right heart function. In the context of structural heart interventions such as transcatheter aortic valve implantation<span> (TAVI), transcatheter edge-to-edge mitral repair (TEER), and transcatheter tricuspid therapies, RV–PA coupling has emerged as a powerful prognostic indicator. Impaired coupling, typically defined using echocardiographic surrogates such as the tricuspid annular plane systolic excursion (TAPSE)/pulmonary artery systolic pressure (PASP) ratio, is consistently associated with increased mortality and heart failure hospitalization. RV–PA coupling also demonstrates dynamic behavior, with potential for improvement following intervention—though persistent uncoupling portends worse outcomes. Despite its clinical promise, significant limitations exist. Commonly used non-invasive indices, while practical, only moderately correlate with gold-standard invasive pressure-volume loop assessments and are subject to measurement variability and lack of standardization. Furthermore, current surrogates do not distinguish between the underlying drivers of uncoupling—whether impaired </span></span>contractility<span> or increased afterload—each with distinct therapeutic implications. As structural heart interventions expand to broader patient populations, a more refined understanding of RV–PA coupling may enhance risk stratification, procedural planning, and long-term management. Future research should focus on standardizing assessment techniques and establishing evidence-based thresholds to support its routine clinical use.</span></span></div></div>","PeriodicalId":47657,"journal":{"name":"Cardiovascular Revascularization Medicine","volume":"78 ","pages":"Pages 113-119"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of protamine sulfate following carotid artery stenting.","authors":"William Nicholson, Khaled I Alnahhal, John Han, Jacob Borenstein, Keivan Ranjbar, Stephanie D Talutis, Shivani Kumar, Payam Salehi","doi":"10.1016/j.carrev.2025.08.011","DOIUrl":"https://doi.org/10.1016/j.carrev.2025.08.011","url":null,"abstract":"<p><strong>Background: </strong>protamine sulfate is used to reduce bleeding risk after Carotid Artery Stenting (CAS), but its efficacy in personalized patient settings remains underexplored. This study aims to identify factors associated with greater benefits from protamine sulfate following CAS.</p><p><strong>Methods: </strong>A retrospective review of Vascular Quality Initiative (VQI) data (2016-2022) identified patients undergoing CAS, divided into Transfemoral CAS (TF-CAS) and Transcarotid artery revascularization (TCAR) groups. Multivariate analysis used to identify perioperative predictors of bleeding complications, and propensity score matching compared rates of death and thrombotic events (myocardial infarction (MI), stroke/transient ischemic attack (TIA)) between protamine and no protamine groups.</p><p><strong>Results: </strong>Among 51,473 patients (36.9 % females), 56.4 % underwent TCAR (Protamine: 85.6 %; No protamine: 14.4 %), and 43.6 % underwent TF-CAS (Protamine: 18.9 %; No protamine: 81.1 %). Protamine significantly reduced bleeding complications in female patients and those on ACE inhibitors in both groups. In the TF-CAS group, protamine was associated with lower all-cause mortality (7.9 % vs. 11.5 %; P < .001) without an increase in MI (0.5 % vs. 0.9 %) or stroke/TIA (2.8 % vs. 2.9 %; P > .05). In the TCAR group, protamine had similar rates of all-cause mortality (7.7 % vs. 7.3 %), MI (0.4 % vs. 0.3 %), and stroke/TIA (2.4 % vs. 2.9 %; P > .05).</p><p><strong>Conclusions: </strong>Protamine sulfate appears to be effective in reducing the bleeding complications in TCAR patients without increasing death or thrombotic complications. Its benefits are especially notable in females and those on ACE inhibitors, regardless of the CAS approach. Although protamine use in the TF-CAS cohort was associated with reduced all-cause mortality, it did not show an overall benefit in bleeding reduction. However, in TF-CAS, females and patients on ACE inhibitors did appear to benefit, supporting a more selective approach to its use.</p>","PeriodicalId":47657,"journal":{"name":"Cardiovascular Revascularization Medicine","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145030838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Young adults with acute coronary syndrome undergoing percutaneous coronary intervention: Insights from the Houston Methodist Young ACS-PCI Registry","authors":"Safi U. Khan ,&nbsp;Rody G. Bou Chaaya ,&nbsp;Taha Hatab ,&nbsp;Sahar Samimi ,&nbsp;Fatima Qamar ,&nbsp;Chloe Kharsa ,&nbsp;Hassaan B. Arshad ,&nbsp;Syed Zaid ,&nbsp;Joe Aoun ,&nbsp;Kershaw V. Patel ,&nbsp;Khurram Nasir ,&nbsp;Sadeer Al-Kindi ,&nbsp;William Zoghbi ,&nbsp;Sachin S. Goel ,&nbsp;Alpesh R. Shah ,&nbsp;Neal S. Kleiman","doi":"10.1016/j.carrev.2024.11.007","DOIUrl":"10.1016/j.carrev.2024.11.007","url":null,"abstract":"<div><h3>Background</h3><div>Limited data exist on the risk profile and prognosis of young patients undergoing percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS). This study sheds light on the burden of cardiovascular risk factors and outcomes in this population.</div></div><div><h3>Methods</h3><div>The Houston Methodist Young ACS-PCI registry is a retrospective analysis of young adults (18 to 50 years) undergoing PCI for ACS between 2010 and 2022. Outcomes of interest were major adverse cardiovascular events (MACE: all-cause mortality, myocardial infarction (MI), ischemic stroke) at one year.</div></div><div><h3>Results</h3><div><span>Among 629 patients (median age, 46 years, 23.5% women, and 65.3% White adults), 69.2% had Non-ST-Segment Elevation MI. A total of 22.7% had prior MI, 26.2% prior PCI, and 9.2% had prior coronary artery bypass graft<span> surgery. The prevalence of active smoking, dyslipidemia<span>, hypertension, and diabetes was 69.4%, 82.2%, 80.4%, and 39.6%, respectively. Age-adjusted diabetes rates increased over time, while dyslipidemia, hypertension, and obesity rates remained unchanged. The </span></span></span>femoral artery was the most common arterial access (85.2%), 72.7% had one vessel disease, 44.3% had the left anterior descending artery as the culprit vessel, and 78.5% of patients received one stent. At a median of 3.8 years, all-cause mortality was 28 deaths per 1000 person-years. At one year, 11.4% experienced MACE; racial and ethnic minority (Black, Hispanic, and Others), dialysis, prior MI, and stent diameter were independent predictors of MACE.</div></div><div><h3>Conclusions</h3><div>The study highlights a notable burden of cardiovascular risk factors and cardiovascular outcomes in young adults with ACS undergoing PCI, underscoring the need for strategies to enhance risk assessment and guide interventions among young adults.</div></div>","PeriodicalId":47657,"journal":{"name":"Cardiovascular Revascularization Medicine","volume":"78 ","pages":"Pages 15-22"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142696009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: Comparison of FFRangio sizing tool and IVUS measurements - So how does it measure up?","authors":"Krystyna Bronchard ,&nbsp;Edward Ha ,&nbsp;Yuhei Kobayashi","doi":"10.1016/j.carrev.2025.04.037","DOIUrl":"10.1016/j.carrev.2025.04.037","url":null,"abstract":"","PeriodicalId":47657,"journal":{"name":"Cardiovascular Revascularization Medicine","volume":"78 ","pages":"Pages 86-87"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144041466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evoque transcatheter tricuspid valve replacement in a patient with multiple right-sided leads using intracardiac echocardiography alone with the “Back-Bend” technique","authors":"Deven R. Rajagopal ,&nbsp;Rishab Jayanthi ,&nbsp;James P. Stewart ,&nbsp;Hassan S. Sayegh ,&nbsp;Peter B. Flueckiger ,&nbsp;Sara Mobasseri ,&nbsp;Mani A. Vannan ,&nbsp;Vinod H. Thourani ,&nbsp;Pradeep K. Yadav","doi":"10.1016/j.carrev.2025.03.010","DOIUrl":"10.1016/j.carrev.2025.03.010","url":null,"abstract":"","PeriodicalId":47657,"journal":{"name":"Cardiovascular Revascularization Medicine","volume":"78 ","pages":"Pages 108-110"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anticoagulation alone versus large-bore mechanical thrombectomy in acute intermediate-risk pulmonary embolism","authors":"Robert S. Zhang ,&nbsp;Eugene Yuriditsky ,&nbsp;Peter Zhang ,&nbsp;Hannah P. Truong ,&nbsp;Yuhe Xia ,&nbsp;Muhammad H. Maqsood ,&nbsp;Allison A. Greco ,&nbsp;Vikramjit Mukherjee ,&nbsp;Radu Postelnicu ,&nbsp;Nancy E. Amoroso ,&nbsp;Thomas S. Maldonado ,&nbsp;Carlos L. Alviar ,&nbsp;James M. Horowitz ,&nbsp;Sripal Bangalore","doi":"10.1016/j.carrev.2025.03.023","DOIUrl":"10.1016/j.carrev.2025.03.023","url":null,"abstract":"<div><h3>Background</h3><div><span>Patients with intermediate-risk pulmonary embolism<span> (PE) have outcomes worse than uncomplicated ST elevation myocardial infarction. Yet, no large-scale study has compared the outcomes of large-bore </span></span>mechanical thrombectomy<span> (LBMT) with anticoagulation alone (AC). The aim of this study was to compare the clinical outcomes among patients receiving LBMT vs AC alone.</span></div></div><div><h3>Methods</h3><div><span>This was a two-center retrospective study that included patients with intermediate-risk PE from October 2016 – October 2023 from the institution's Pulmonary Embolism Response Team (PERT) database. The primary outcome was a composite of 30-day mortality, resuscitated cardiac arrest or </span>hemodynamic<span> decompensation. Inverse probability of treatment weighting (IPTW) was used to balance covariates; Kaplan Meir curves and IPTW multivariable Cox regression were used to assess the relationship between treatment groups and outcomes.</span></div></div><div><h3>Results</h3><div>Of the 273 patients included in the analysis, 192 (70 %) patients received AC alone and 81 (30 %) patients received LBMT and AC. A total of 30 (10.9 %) patients experienced the primary composite outcome over a median follow-up of 30 days. The primary composite outcome was significantly lower in the group that received LBMT compared to those on AC alone (1.2 % vs 15.1 %, log-rank <em>p</em> &lt; 0.001; adjusted HR: 0.02; 95 % CI: 0.002–0.17, p &lt; 0.001) driven by a lower rate of 30-day all-cause mortality (0 % vs 7.3 %, log-rank <em>p</em> = 0.01), resuscitated cardiac arrest (0 % vs 6.8 %, log-rank <em>p</em> = 0.016) and new or worsening hemodynamic instability (4 % vs 11.1 %, log-rank <em>p</em> = 0.007).</div></div><div><h3>Conclusion</h3><div>In this largest cohort to date comparing LBMT versus AC alone in acute intermediate-risk PE, LBMT had a significantly lower rate of the primary composite outcome including a lower rate of all-cause mortality when compared to AC alone. Ongoing randomized trials will test these associations.</div></div>","PeriodicalId":47657,"journal":{"name":"Cardiovascular Revascularization Medicine","volume":"78 ","pages":"Pages 47-54"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcatheter treatment of dual aortic-mitral pathology using transcatheter aortic valve replacement and transcatheter mitral edge-to-edge repair","authors":"Andres Cordova Sanchez,&nbsp;Rony N. Lahoud,&nbsp;Peter VanBuren,&nbsp;Harold L. Dauerman,&nbsp;Tanush Gupta","doi":"10.1016/j.carrev.2025.04.003","DOIUrl":"10.1016/j.carrev.2025.04.003","url":null,"abstract":"","PeriodicalId":47657,"journal":{"name":"Cardiovascular Revascularization Medicine","volume":"78 ","pages":"Pages 111-112"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}