Special Care in Dentistry最新文献

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Comment on "Eating and Swallowing Issues in Students Enrolled in Special Education Schools for Intellectual Disabilities". 评《智障特殊教育学校学生进食及吞咽问题》
IF 1.4
Special Care in Dentistry Pub Date : 2026-07-01 DOI: 10.1111/scd.70208
Deepti M Sati, Vanashri Dhananjay Shinde, Chhaya Agarwal
{"title":"Comment on \"Eating and Swallowing Issues in Students Enrolled in Special Education Schools for Intellectual Disabilities\".","authors":"Deepti M Sati, Vanashri Dhananjay Shinde, Chhaya Agarwal","doi":"10.1111/scd.70208","DOIUrl":"https://doi.org/10.1111/scd.70208","url":null,"abstract":"","PeriodicalId":47470,"journal":{"name":"Special Care in Dentistry","volume":"46 4","pages":"e70208"},"PeriodicalIF":1.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148346928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Qualitative Evaluation of the Autism Awareness of Pediatric Dentistry Residents of a Public University in Istanbul, Turkiye. 土耳其伊斯坦布尔一所公立大学儿科牙科住院医师自闭症认知的定性评价。
IF 1.4
Special Care in Dentistry Pub Date : 2026-07-01 DOI: 10.1111/scd.70234
Melda Karavuş, Hatice Büşra Arısın, Ezgi Didem Bakırkaynak, Zeynep Akkuzugil, Selin Ece Tahan, Mehmet Emre Kekeç, Emre Akkuş, Şevket Girgin, Nimet Emel Lüleci, Seyhan Hıdıroğlu
{"title":"Qualitative Evaluation of the Autism Awareness of Pediatric Dentistry Residents of a Public University in Istanbul, Turkiye.","authors":"Melda Karavuş, Hatice Büşra Arısın, Ezgi Didem Bakırkaynak, Zeynep Akkuzugil, Selin Ece Tahan, Mehmet Emre Kekeç, Emre Akkuş, Şevket Girgin, Nimet Emel Lüleci, Seyhan Hıdıroğlu","doi":"10.1111/scd.70234","DOIUrl":"10.1111/scd.70234","url":null,"abstract":"<p><strong>Aims: </strong>This study aimed to qualitatively evaluate the awareness, knowledge levels, and clinical approaches of dental residents regarding the dental management and characteristics of individuals with Autism Spectrum Disorder (ASD).</p><p><strong>Methods and results: </strong>Using a phenomenological qualitative design, data were collected through semi-structured, in-depth interviews with dental residents at a public university in Istanbul, Türkiye. Transcripts were analyzed via ATLAS-ti software to identify themes and sub-themes. Residents recognized key ASD traits such as repetitive behaviors, sensory sensitivities, and communication barriers. The theme \"Experience During Examination\" highlighted significant challenges, including patients' difficulty following instructions and fear of the clinical setting. Results indicated that residents utilize behavioral management strategies, such as providing isolated, low-stimulus environments and using visual aids or relaxing music. While some managed difficulties through adapted interactions, others reported a need to refer patients for conscious sedation or general anesthesia for invasive procedures.</p><p><strong>Conclusion: </strong>Although dental residents demonstrate a foundational awareness of ASD, they face practical challenges in clinical examination and treatment. Enhancing specialized training in behavioral management and providing low-stimulus clinical settings are essential to improve oralhealthcare outcomes for patients with ASD.</p>","PeriodicalId":47470,"journal":{"name":"Special Care in Dentistry","volume":"46 4","pages":"e70234"},"PeriodicalIF":1.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13471873/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148725733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High-Power Surgical Laser for Treatment of Oral Manifestations of Mucopolysaccharidosis VI: A Case Report. 高功率激光手术治疗口腔粘多糖病1例。
IF 1.4
Special Care in Dentistry Pub Date : 2026-07-01 DOI: 10.1111/scd.70224
Regina Maria Raffaele, Mario Eduardo Baldo, Bianca Ribeiro Marques, Stefan Gabriel Gonçalves Martiniano, Gleyson Kleber do Amaral Silva, Rafael Ferreira
{"title":"High-Power Surgical Laser for Treatment of Oral Manifestations of Mucopolysaccharidosis VI: A Case Report.","authors":"Regina Maria Raffaele, Mario Eduardo Baldo, Bianca Ribeiro Marques, Stefan Gabriel Gonçalves Martiniano, Gleyson Kleber do Amaral Silva, Rafael Ferreira","doi":"10.1111/scd.70224","DOIUrl":"10.1111/scd.70224","url":null,"abstract":"<p><p>Mucopolysaccharidosis type VI (MPS VI), a rare metabolic disorder, results from glycosaminoglycan accumulation in tissues, frequently leading to hyperplastic gingival alterations that necessitate comprehensive intervention. An 11-year-old male patient diagnosed with MPS VI required hospitalization due to complications associated with a ventriculoperitoneal shunt (VPS) valve. A dental evaluation identified bone malformation in the maxillomandibular complex accompanied by pronounced gingival hyperplasia. The surgical team performed a gingivoplasty in the operating room under general anesthesia, employing a combined technique involving manual scalpels and a diode laser to excise hyperplastic gingival tissue and cauterize bleeding sites. The patient exhibited an uneventful postoperative recovery, with no hemorrhagic or infectious complications. The diode laser demonstrated safety and efficacy in removing gingival tissue in this patient with MPS VI, facilitating local tissue repair, enhancing the aesthetic and functional profile, and ultimately improving the patient's oral health and quality of life.</p>","PeriodicalId":47470,"journal":{"name":"Special Care in Dentistry","volume":"46 4","pages":"e70224"},"PeriodicalIF":1.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13452063/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148698167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of an Educational Intervention on Oral Health Knowledge Among Nursing Staff Caring for Hospitalized Patients in a Brazilian Hospital: A Quasi-Experimental Study. 教育干预对巴西某医院护理人员口腔健康知识影响的准实验研究
IF 1.4
Special Care in Dentistry Pub Date : 2026-07-01 DOI: 10.1111/scd.70239
Geisiane Garcias Moreira, William Vinícius Oliveira Dos Santos, Lilian Rigo
{"title":"Impact of an Educational Intervention on Oral Health Knowledge Among Nursing Staff Caring for Hospitalized Patients in a Brazilian Hospital: A Quasi-Experimental Study.","authors":"Geisiane Garcias Moreira, William Vinícius Oliveira Dos Santos, Lilian Rigo","doi":"10.1111/scd.70239","DOIUrl":"https://doi.org/10.1111/scd.70239","url":null,"abstract":"<p><strong>Aim: </strong>To assess the effect of an educational intervention on nursing professionals' knowledge of hospital oral hygiene and associated factors.</p><p><strong>Methods: </strong>A single-group quasi-experimental study was conducted in a hospital in southern Brazil, including 138 nursing professionals (mean age: 35.46 ± 9.49 years). The intervention comprised three stages: a pre-test, a protocol-based educational session delivered by two dental surgeons, and a post-test. Data were analyzed using descriptive statistics, McNemar's test, and Pearson's chi-square test (α = 0.05).</p><p><strong>Results: </strong>Before the intervention, 19.6% of participants had never received academic instruction on oral hygiene, 59.4% had not received institutional training, and 37.7% were unaware of an institutional protocol. After the intervention, correct answers reached ≥95% in 15 of 19 items and 100% in four items (p < 0.001). The greatest improvements were observed for oral hygiene before bathing intubated patients (43.5% to 85.5%), and toothbrush use in hospital settings (52.9% to 85.5%). Higher baseline knowledge was associated with the presence of an institutional oral hygiene protocol (p < 0.05).</p><p><strong>Conclusion: </strong>The educational intervention improved nursing professionals' knowledge of hospital oral hygiene. Institutional protocols were associated with higher baseline knowledge, reinforcing the importance of continuing education and standardized protocols to support safe, evidence-based care.</p>","PeriodicalId":47470,"journal":{"name":"Special Care in Dentistry","volume":"46 4","pages":"e70239"},"PeriodicalIF":1.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13495651/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148799609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Non-Invasive Management of Osteoradionecrosis With Intra- and Extraoral Fistulas Using Combined Photodynamic and Photobiomodulation Therapy: A Case Report. 应用光动力和光生物调节联合治疗口内口外瘘伴放射性骨坏死1例。
IF 1.4
Special Care in Dentistry Pub Date : 2026-07-01 DOI: 10.1111/scd.70214
Alyne Simões, Fabio de Abreu Alves, Caio Camargo Calarga, Luciane Hiramatsu Azevedo, Claudia Carrara Cotomacio
{"title":"Non-Invasive Management of Osteoradionecrosis With Intra- and Extraoral Fistulas Using Combined Photodynamic and Photobiomodulation Therapy: A Case Report.","authors":"Alyne Simões, Fabio de Abreu Alves, Caio Camargo Calarga, Luciane Hiramatsu Azevedo, Claudia Carrara Cotomacio","doi":"10.1111/scd.70214","DOIUrl":"10.1111/scd.70214","url":null,"abstract":"<p><strong>Aims: </strong>Osteoradionecrosis (ORN) is a severe late complication of head and neck radiotherapy, often refractory to conventional treatment. Photobiomodulation therapy (PBMT) and photodynamic therapy (PDT) have shown regenerative, analgesic, and antimicrobial effects. This report aims to describe the non-invasive management of extensive mandibular ORN with intra- and extraoral fistulas using a combined PBMT-PDT protocol.</p><p><strong>Case report: </strong>A 72-year-old man previously treated with chemoradiation for laryngeal carcinoma developed chronic mandibular ORN after third molar extraction, complicated by a pathologic fracture, persistent suppuration, and failure of surgery, hyperbaric oxygen, antibiotics, and curettage. Clinical evaluation revealed intra- and extraoral suppurative fistulas and radiographic bone sequestration. A conservative regimen was initiated, consisting of weekly PBMT and PDT sessions following chlorhexidine irrigation. Over approximately one year (50 sessions), the patient reported progressive pain relief and reduced analgesic use. Complete closure of both fistulas was achieved, with recovery of soft-tissue sensitivity and radiographic resolution of sequestration. No adverse effects occurred, and the planned surgical debridement was canceled.</p><p><strong>Conclusion: </strong>Combined PBMT and PDT promoted complete resolution of extensive, refractory mandibular ORN using a fully non-invasive approach. This case highlights the synergistic potential of dual phototherapy as a safe and effective alternative when surgery is contraindicated or declined. Further studies are warranted to clarify underlying mechanisms and optimize treatment parameters.</p>","PeriodicalId":47470,"journal":{"name":"Special Care in Dentistry","volume":"46 4","pages":"e70214"},"PeriodicalIF":1.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13358455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148431301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of Oral Health Status, Oral Health Beliefs, and Tobacco Habits Among the Katkari Tribe in Goa, India: A Cross-Sectional Study. 印度果阿Katkari部落的口腔健康状况、口腔健康信念和吸烟习惯评估:一项横断面研究。
IF 1.4
Special Care in Dentistry Pub Date : 2026-07-01 DOI: 10.1111/scd.70197
Apurva Prashant Deshpande, Fhelen Da Costa, Vinayak Kamath, Amita Kenkre Kamat, Ridhima Gaunkar, Akshatha Gadiyar
{"title":"Assessment of Oral Health Status, Oral Health Beliefs, and Tobacco Habits Among the Katkari Tribe in Goa, India: A Cross-Sectional Study.","authors":"Apurva Prashant Deshpande, Fhelen Da Costa, Vinayak Kamath, Amita Kenkre Kamat, Ridhima Gaunkar, Akshatha Gadiyar","doi":"10.1111/scd.70197","DOIUrl":"https://doi.org/10.1111/scd.70197","url":null,"abstract":"<p><strong>Background: </strong>The Katkari tribe in Goa, India, faces significant oral health challenges due to cultural beliefs, poor access to healthcare, and high tobacco consumption. This study aims to assess the oral health status, oral health beliefs, and tobacco habits within this isolated community.</p><p><strong>Methods: </strong>A descriptive cross-sectional study was conducted among 101 participants from tribal settlements in North and South Goa between October and December 2023. A structured questionnaire was used to collect data on sociodemographics, oral hygiene practices, myths about oral health, and tobacco use. Participants underwent clinical examination using the WHO Oral Health Assessment Form. Data analysis was performed using IBM SPSS version 20, with descriptive statistics and Chi-Square test and Fisher's exact test to explore associations between variables.</p><p><strong>Results: </strong>The mean age of participants was 28.9 years, with 57.4% females. Most participants had low educational levels, and 64.35% reported using toothbrushes for oral hygiene. However, brushing habits were suboptimal, with 64.4% using incorrect brushing techniques. Myths such as \"clove oil relieves toothache\" (68.3%) and \"tobacco relieves toothache\" (51.5%) were prevalent. Tobacco use was high, with 66.3% consuming smokeless tobacco, and the most common reasons for use were family influence (37.6%) and peer pressure (28.7%). Education and occupation significantly influenced oral health behavior and tobacco habits.</p><p><strong>Conclusion: </strong>The study highlights the significant oral health challenges faced by the Katkari tribe, including poor hygiene practices, high tobacco use, and widespread myths. These issues are compounded by low education levels and limited healthcare access. Culturally sensitive health education, community-based interventions, and tobacco cessation programs are needed to address these challenges and improve the overall health of the community.</p>","PeriodicalId":47470,"journal":{"name":"Special Care in Dentistry","volume":"46 4","pages":"e70197"},"PeriodicalIF":1.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148346996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adverse Oral Mucosal Reaction to Sublingual Captopril: A Case Report With Exploratory Insights Into AI-Assisted Clinical Reasoning. 卡托普利舌下口腔黏膜不良反应:一例人工智能辅助临床推理的探索性见解
IF 1.4
Special Care in Dentistry Pub Date : 2026-07-01 DOI: 10.1111/scd.70228
Antônio Roberto Garcia Júnior, Catarina Melquiades Velane, Caroline Akemi Mendes Magario, Paulo Sergio Pina, Carina Domaneschi, Camilla Vieira Esteves
{"title":"Adverse Oral Mucosal Reaction to Sublingual Captopril: A Case Report With Exploratory Insights Into AI-Assisted Clinical Reasoning.","authors":"Antônio Roberto Garcia Júnior, Catarina Melquiades Velane, Caroline Akemi Mendes Magario, Paulo Sergio Pina, Carina Domaneschi, Camilla Vieira Esteves","doi":"10.1111/scd.70228","DOIUrl":"10.1111/scd.70228","url":null,"abstract":"<p><strong>Aims: </strong>To describe a probable oral mucosal injury associated with the off-label sublingual administration of captopril in a medically complex patient, and to illustrate the role of structured clinical reasoning in identifying route-related adverse drug reactions, with exploratory insights into AI-assisted reasoning.</p><p><strong>Methods and results: </strong>A 77-year-old patient presented with persistent burning pain and a progressive oral mucosal lesion on the floor of the mouth. Despite appropriate management of local infectious and mechanical factors, symptoms worsened over time. A consistent temporal relationship was observed between lesion exacerbation and repeated sublingual captopril use during hypertensive episodes. Structured clinical reasoning, including iterative causal analysis, supported identification of a probable route-related adverse drug reaction. Discontinuation of sublingual captopril, combined with topical corticosteroid therapy, resulted in complete resolution of the lesion. An exploratory interaction with a large language model was conducted to examine how structured clinical input may influence the coherence and clinical relevance of AI-assisted reasoning.</p><p><strong>Conclusion: </strong>Sublingual administration of captopril may cause localized chemical injury to the oral mucosa, particularly in vulnerable patients with complex medical conditions. Recognition of route-specific adverse effects is essential to avoid unnecessary interventions and improve patient outcomes. This case also illustrates that AI-assisted reasoning is highly dependent on the structure and quality of clinical input, supporting its role as a complementary cognitive tool rather than an autonomous diagnostic system.</p>","PeriodicalId":47470,"journal":{"name":"Special Care in Dentistry","volume":"46 4","pages":"e70228"},"PeriodicalIF":1.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13401081/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148585620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Expanding the Phenotypic Spectrum of Degcags Syndrome: Novel Craniofacial and Oral Findings. 扩大Degcags综合征的表型谱:颅面和口腔的新发现。
IF 1.4
Special Care in Dentistry Pub Date : 2026-07-01 DOI: 10.1111/scd.70232
Jeferson Paiva, Lucas Batista-Fontes, Janaína Taíza Araújo de Jesus, Kelly Fernanda Molena, Raquel Assed Bezerra da Silva, Kranya Victoria Diaz-Serrano, Francisco Wanderley Garcia de Paula-Silva, Alexandra Mussolino de Queiroz, Fabrício Kitazono de Carvalho
{"title":"Expanding the Phenotypic Spectrum of Degcags Syndrome: Novel Craniofacial and Oral Findings.","authors":"Jeferson Paiva, Lucas Batista-Fontes, Janaína Taíza Araújo de Jesus, Kelly Fernanda Molena, Raquel Assed Bezerra da Silva, Kranya Victoria Diaz-Serrano, Francisco Wanderley Garcia de Paula-Silva, Alexandra Mussolino de Queiroz, Fabrício Kitazono de Carvalho","doi":"10.1111/scd.70232","DOIUrl":"10.1111/scd.70232","url":null,"abstract":"<p><strong>Aims: </strong>Developmental delay with gastrointestinal, cardiovascular, genitourinary, and skeletal abnormalities (DEGCAGS) syndrome (OMIM #619488) is a rare autosomal recessive disorder caused by pathogenic variants in ZNF699 and characterized by developmental delay and multisystem involvement. Although several systemic and craniofacial manifestations have been described, oral findings have not yet been reported. This case report describes the craniofacial and oral features of a patient with DEGCAGS syndrome, contributing to the expansion of its phenotypic spectrum.</p><p><strong>Methods and results: </strong>A 10-year-old girl with a homozygous pathogenic variant in ZNF699 was referred for dental evaluation. Clinical examination revealed hair thinning, dolichocephaly, retromicrognathia, synophrys, smooth philtrum, thin upper lip, increased overjet, and deep bite. Intraoral findings included generalized spacing, gingivitis, active carious lesions, hypomineralization of primary molars, talon cusps on the maxillary central incisors, erosive tooth wear, and signs consistent with sleep bruxism. Radiographic evaluation revealed taurodontism, particularly in teeth 16 and 26, shortened roots in the mandibular incisors, and increased pericoronal space associated with developing teeth.</p><p><strong>Conclusion: </strong>These findings expand the oral phenotype of DEGCAGS syndrome and highlight the importance of dental evaluation in patients with rare genetic disorders. Further reports are needed to better characterize the oral manifestations associated with this condition.</p>","PeriodicalId":47470,"journal":{"name":"Special Care in Dentistry","volume":"46 4","pages":"e70232"},"PeriodicalIF":1.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13452067/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148698178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
When Surgical Intervention Becomes a Risk: Severe Drug-Induced Gingival Overgrowth and Clinical Decision-Making in Alpers-Huttenlocher Syndrome. 当手术干预成为一种风险:alpers - hutenlocher综合征的严重药物性牙龈过度生长和临床决策。
IF 1.4
Special Care in Dentistry Pub Date : 2026-07-01 DOI: 10.1111/scd.70241
Marcus Vinícius Bueno, Renata Zoraida Rizental Delgado, Karem Ortega, Juliana Bertoldi Franco
{"title":"When Surgical Intervention Becomes a Risk: Severe Drug-Induced Gingival Overgrowth and Clinical Decision-Making in Alpers-Huttenlocher Syndrome.","authors":"Marcus Vinícius Bueno, Renata Zoraida Rizental Delgado, Karem Ortega, Juliana Bertoldi Franco","doi":"10.1111/scd.70241","DOIUrl":"10.1111/scd.70241","url":null,"abstract":"<p><strong>Introduction: </strong>Alpers-Huttenlocher syndrome (AHS) is an ultra-rare, autosomal recessive mitochondrial encephalopathy caused by pathogenic POLG variants, characterized by refractory epilepsy, hepatic dysfunction, and progressive neurodegeneration. Drug-induced gingival overgrowth (DIGO) is a recognized complication of anticonvulsant and immunosuppressive therapy, particularly in medically complex patients. This report describes severe DIGO in a child with genetically confirmed AHS and explores the implications for multidisciplinary dental management.</p><p><strong>Methods: </strong>A CARE-compliant case analysis was conducted in a five-year-old girl with AHS, status post living-donor liver transplantation, chronically hospitalized in a long-term intensive care unit. Clinical findings, pharmacologic exposures, multidisciplinary decision-making, and conservative oral management strategies were systematically documented.</p><p><strong>Results: </strong>The patient, ventilator-dependent and gastrostomy-fed, had prolonged exposure to phenytoin, sodium valproate, topiramate, and tacrolimus without prior dental surveillance. Examination revealed severe fibrotic maxillary gingival overgrowth, delayed tooth eruption, and functional compromise. Given her profound systemic fragility, gingivoplasty under general anesthesia was contraindicated. A structured conservative protocol including 0.12% chlorhexidine, mucosal care, and continuous dental follow-up was implemented to reduce inflammatory and infectious burden.</p><p><strong>Conclusion: </strong>This case underscores the necessity of integrating dental care into the multidisciplinary management of rare mitochondrial disorders and represents, to our knowledge, the first reported association between AHS and severe DIGO.</p>","PeriodicalId":47470,"journal":{"name":"Special Care in Dentistry","volume":"46 4","pages":"e70241"},"PeriodicalIF":1.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13502216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148809438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bruxism in Autistic and Neurotypical Children: Associations With Medication Use and Sleep. 自闭症和神经正常儿童的磨牙症:与药物使用和睡眠的关系。
IF 1.4
Special Care in Dentistry Pub Date : 2026-07-01 DOI: 10.1111/scd.70217
Pedro Vitali Kammer, Natalia Goes Nascimento, Juliana da Silva Moro, Michele Bolan
{"title":"Bruxism in Autistic and Neurotypical Children: Associations With Medication Use and Sleep.","authors":"Pedro Vitali Kammer, Natalia Goes Nascimento, Juliana da Silva Moro, Michele Bolan","doi":"10.1111/scd.70217","DOIUrl":"10.1111/scd.70217","url":null,"abstract":"<p><strong>Objective: </strong>To examine whether medication use, sleep quality, and anxiety were associated with bruxism in autistic and neurotypical children.</p><p><strong>Methods and results: </strong>Cross-sectional parent-reported data were collected from 227 children aged 4-12 years, including 40 autistic and 187 neurotypical children. Associations with bruxism were examined using multivariable logistic regression, with stratified and exploratory subgroup analyses. Medication use was not associated with bruxism in the full sample or subgroup analyses. Agitated sleep was associated with higher odds of bruxism in the full sample (AOR = 2.23, p = 0.005) and the neurotypical subgroup (OR = 2.95, p = 0.002), but not in the autistic subgroup. Increasing age was inversely associated with bruxism (AOR = 0.74, p = 0.035). Autism diagnosis, sex, and anxiety were not independently associated with the outcome. Exploratory analyses within the autistic subgroup found no significant associations for sensory differences and support needs.</p><p><strong>Conclusions: </strong>Medication use was not associated with bruxism, whereas agitated sleep was associated with higher odds of bruxism in the full sample and neurotypical subgroup. Findings should be interpreted cautiously given the cross-sectional design, parent-reported measures, small and predominantly male autistic subgroup, and absence of medication dosage data.</p>","PeriodicalId":47470,"journal":{"name":"Special Care in Dentistry","volume":"46 4","pages":"e70217"},"PeriodicalIF":1.4,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13352304/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148425242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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